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이재홍,이상도,이일두,정주섭,노성민,박병엽,조현장,김승영 대한내과학회 1996 대한내과학회지 Vol.51 No.1
Actinomycosis is chronic suppurative and granulomatous disease caused by anaerobic, gram positive filamentous bacterium, The most common sites of involvement are the cervicofascial area, thorax, abdomen and pelvis. Primary hepatic actinomycosis is rare and presents a diagnostic challenge. A 57-year old man was admitted because of right upper quadrant abdominal pain and fever for 1 month. abdominal ultrasonography, computed tomography examination showed mass lesion in liver. Primary hepatic actinomycosis was confirmed by identification of sulfur granule, ultrasonography-guided percutaneous needle aspiration. We report a case of primary hepatic actinomycosis, emphasizing the role of imaging study followed by percutaneous liver biopsy in a condition which frequently requires laparotomy for diagnosis.
김용기,이재복,김인주,최철수,이일두 대한내분비학회 1993 Endocrinology and metabolism Vol.8 No.1
The multiple endocrine neoplasia (MEN) syndromes were classified into two broad categories, MEN type I (MEN I) and MEN type II(MEN II). The MEN II syndrome has been further subcategorized into two variants called MEN Iia and MEN Iib (formerly MEN III). There are a number of rare hereditary MEN syndromes which do not fit the MEN I or MEN II categories, which is called as mixed type. This mixed thpe MEN occurs very rarely. In 1978, Tateishi et al. Reported a case of bilateral pheochromocytoma associated with pancreatic islet cell tumor for the first time. Thereafter, only several cases of such mixed type MEN have been reported all over the world. However there was no case report of a mixed type MEN in Korea. Recently, we experienced qa case of familial pheochromocytoma associated with parcreatic islet cell tumor. A pancreatic islet cell tumor occurred in a 25-year old woman who received a bilateral adrenalectomy for pheochromocytoma 6 hears ago. She had family history of mother and younger sister diagnosed as having pancreaic head tumor, and younger brother who had been ooperated for pheochromocytoma and conifirmed hestologically. (J Kor Soc Endocrinol 8:100~105, 1993)
김동수,김용기,박인철,손덕현,이일두,정희,차광수,강필중,이정유 대한내과학회 1990 대한내과학회지 Vol.39 No.5
Rhinocerebral mucormycosis is a serious and commonly fatal fungal infection. The causative organism. ordinarily a saprophyte, becomes pathogenic in person who are made susceptible by coexisting. debilitating disease such as diabetic ketoacidosis and immunosup-pressed condition. We report a well-documented case of rhinocerebral mucormycosis in not controlled diabetic woman, Her condition rapidly deteriorated. The diagnosis was con- firmed by demonstration of the characteristic broad, branching, nonseptate hyphae by histopathology. And the mucormycete Rhizopus was isolated from the infected tissue culture.
Chloroquine저항성 유입 말라리아 14예에 대한 임상적 고찰
이재홍,노성민,이상도,이일두,박병엽,정주섭 대한감염학회 1994 감염 Vol.26 No.4
Recently the prevalence of malaria and chloroquine-resistant malaria has been increasing around the world and there is an increasing concern about exogenous malaria in non-endemic areas. We reported 14 cases of chloroquine-resistant imported malaria seen at the Hae Dong Hospital from 1992 to May 1994 with a review of the literatures. The following is a summary of the findings. 1) All cases were physically active men with a mean age of 38.6 years and were infected with chloroquine-resistant species. 2) The 11cases were Plasmodium falciparum infection and the other cases were undetermined. 3) The majority(93%) of patients had malaria imported from Africa. 4) All patients had fever, chill, generalized malaise. Gastrointestinal symptoms and hepatosplenomegaly were developed in 50% of patients. 5) About 20% of the patients had serious complications such as hemolytic anemia, acute renal failure and jaundice. 6) In the 3cases of severe malaria, intravenous quinine therapy was attempted and treated successfully. The other cases of chloroquine-resistant malaria were treated with quinine plus tetracycline combination therapy and Fansidar. In the cases, which can not be tolerable because of side effects and resist to above therapy, therapy was substituted to halofantrine. 7) Halofantrine is effective against chloroquine-resistant malaria and recommended the alternative therapy of multidrug resistant malaria.
Sjogren 증후군 동반한 류마토이드 관절염환자에서 원위부 신세뇨관성 산증
김영수,김성일,이준상,김무영,나하연,곽임수,양용석,이일두 대한신장학회 1993 Kidney Research and Clinical Practice Vol.12 No.4
Distal renal tubular acidosis is classified into primary and secondary. Primary distal RTA is hereditary. Secondary distal RTA associated with hereditary disease such as lithium, amphotericin B, toluene, Sjogren syndrome is chronic inflammatory autoimmune disease involving lacrimal, salivary gland and other connective tissues resulting in xerostomia and xerophtalmia. In Sjogren syndrom, many renal tubular defects occur and distal RTA is most common renal tubular defect. We expirenced a 39 year-old female patient who had distal RTA in Sjogren sydrome with Rheumatoid arthritis.