http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
방광외벽에 대한 영구적 생체이식장치의 코팅물질로서 Parylene-C의 생체적합성연구
이동섭,김수진,손동완,최범규,이문규,이승준,김세웅 대한남성과학회 2010 The World Journal of Men's Health Vol.28 No.3
Purpose: Development of an implantable bladder volume sensor that could reduce complications and improve the quality of life for neurogenic bladder patients is assignment task that falls in the field of urology. Nevertheless, there is lack of research on whether biomaterials are biocompatible to the urinary bladder or not. Polyethylene glycol (PEG), polydimethylsiloxane (PDMS) and parylene-C are well known biocompatible materials in other fields of medicine. Because PEG is biodegradable and PDMS has a relatively low affinity to substrate with less durability than parylene-C, we evaluated the biocompatibility of parylene-C to the urinary bladde,r comparing of it to PEG and PDMS. Materials and Methods: Nine rabbits were classified into three groups. Coin shaped aluminum substrates were affixed onto the external wall of the urinary bladder in each rabbit. At this point, the three rabbits which had substrates coated with PEG were assigned to group 1, those with PDMS were assigned to group 2 and those with parylene-C were assigned to group 3. In each group, one rabbit was sacrificed at one week, another rabbit was sacrificed at two weeks and the other rabbit was sacrificed at four weeks. At each time microscopic evaluation was done. To detect macrophages, we used fluorescence microscopy and applied MAC 387 staining. Results: At one week, macrophage accumulation was observed on the external surface of the urinary bladder adjacent to the device no matter which material was used as a coating, but it had almost disappeared by four weeks. In addition, the inflammatory reaction was limited at the external surface of the urinary bladder, and did not expand into the muscular layer. Conclusions: With respect to biocompatibility, there was no difference among the three biomaterials. With its characteristics of durability and easy affinity regardless of the type of substrate, parylene-C would make an excellent coating material for a bio-device implantable into the urinary bladder.
이동섭 한국항해항만학회 2013 한국항해항만학회 학술대회논문집 Vol.2013 No.춘계
2013년 11월 27일 구성된 제주 민군복합형 관광미항 크루즈 선박조종 시뮬레이션 시현 TF팀은 2013. 1. 17~18일 한국해양과학기술원에서 3차원 다기능 선박조종시뮬레이터(Full Mission Ship-Handling Simulator)을 이용하여 도선사 4명이 주, 야간 및 입선, 출선자세 접안 16개 시나리오를 가지고 시뮬레이션을 실시하였으며, 평가 기법은 "해사안전법"의 해상교통안전진단 시행지침(국토해양부 고시 제2012-129호(2012.3.21.), 해상교통시스템 적정성 평가(선박조종시뮬레이션, 통항안전성 및 접 이안안전성 평가)를 준용하였다. 시뮬레이션 평가 결과 근접도에 따른 충돌[침범] 확률이 $10^{-4}$ 수식 이미지미만이고, 운항자[주관적] 평가의 결과가 평균 -2.0 이하로 해상교통환경 변화에 따른 통항안전성 및 접이안 안전성 확보가 가능하다고 평가되었다.
선박통항 안전성에서의 주관적 평가의 정량화에 관한 기초연구
이동섭,윤점동,정태권 한국항해항만학회 1994 한국항해학회지 Vol.18 No.4
Assessment of the safety of ship's transit in the narrow channel consist of the maneuvering safety determined by the chance of running aground, the maneuvering difficulty determined by ship's workload and master's subjective evaluation. To examine the relation between master's subjective evaluation and maneuvering safety, this utilizes a real-time and full-mission shiphandling simulator in the Korea Marine Training & Research Institutes(KMTRI). The vessel chosen was 60,000-ton, Panamax-type ship. The findings regarding master's subjective evaluation were as follows: -Relation between master's subjective evaluation and common logarithms of stranding probability is linear. -Stranding probability with more than 0.001 is master's subjective evaluation with more than 5.