비복신경 전도검사의 신뢰도

이경무,변재현,장요한 충북대학교 의과대학 충북대학교 의학연구소 2003 忠北醫大學術誌 Vol.13 No.2

연구목적: 임상 신경연구에 있어서 신경전도검사의 사용이 증가되고 의료비용 증가에 따른 의료행위의 질에 대한 관심이 높아진다는 관점에서 신경전도검사 결과치의 신뢰도에 대한 관심이 높아지고 있다. 이에 신경전도검사의 결과치 중에서 가장 신뢰도가 낮다고 알려진 비복신경에 대한 검사·재검사 및 검사자간 신뢰도와 정상 참고치를 알아보고자 하였다. 대상 및 방법: 말초 신경병증을 의심할 만한 임상증세가 없는 건강한 성인 30명을 대상으로 두 명의 검사자가 각각 한시간 간격으로 비복신경의 기시 잠시, 정점 잠시, 진폭을 구하였고, 첫 번째 검사자는 두 시간 후에 동일 대상을 한번 더 검사하였다. 피어슨 상관계수를 이용하여, 검사·재검사 및 검사자간 신뢰도를 구하였다. 결과: 검사·재검사와 검사자간 신뢰도 평가 결과 base to peak amplitude와 peak to peak amplitude는 신뢰도가 낮았고, 기시 잠시와 정점 잠시는 신뢰도가 높았다. 또한 peak to peak amplitude가 base to peak amplitude보다 신뢰도가 높았고, 기시 잠시가 정점 잠시보다 신뢰도가 높았다(P< 0.01). 정상 참고치는 peak to peak amplitude가 8.67 μV, 기시 잠시가 3.24 ms이었다. 결론: 비복신경 전도검사에서 잠시는 검사·재검사 및 검사자간에서 높은 신뢰도를 보여주었으나, 진폭은 잠시에 비하여 신뢰도가 낮았다. 따라서, 비복신경 전도검사시 신뢰도를 더욱 높이기 위한 표준화된 검사방법이 필요하리라고 생각된다. Purpose: Nerve conduction studies play an important role in clinical practice and research. Given their widespread use, reliability of tests merits careful attention. The objective of this study is to establish the Intra-tester and Inter-tester reliability and normal values of sural nerve conduction study. Materials and Methods: We assessed Intra-tester and Inter-tester reliability of sural nerve measures of amplitude, onset latency, and peak latency. Thirty healthy adults without the clinical signs and symptoms of peripheral neuropathy were evaluated with sural nerve conduction study. Tests were performed on one leg of each subject twice, once by each tester. Tests were performed by one of the two testers on once more 2 hours later. Reliability was assessed with Pearson correlation coefficient. Results: In the Intra-tester and Inter-tester examination, the latencies of the sural nerves showed high correlation. But, amplitudes showed poor correlation(P< 0.01). Normal values of the peak to peak amplitude and the onset latency were 8.67 μV and 3.24 ms. Conclusion: Measures of onset latency and peak latency had higher reliability than amplitude. Of the variables, the onset and peak latency of sural conduction can be used as reliable measures with reasonable Intra-tester and Inter-tester reliability.

흰쥐 Nucleus Raphe Magnus에 투여한 Morphine이 척수 Serotonin 유리에 미치는 영향에 관한 연구

이신재,임요한,최영님,김형룡,정동균 대한구강생물학회 1991 International Journal of Oral Biology Vol.15 No.1

It is known that the interaction between opioid neuron and serotonergic neuron in bulbospinal pathway has an important role on pain control. This experiment was perfomed to directly measure the release of serotonin into spinal cord superfusates before and after the microinjection of morphine and its antagonist, naloxone into the NRM of rats. High performance liquid chromatography with electrochemical detection was used to quantitate the amine. The injection of morphine into the NRM induced a significant increase in the amount of serotonin released in the spinal cord, which was reversed after the intraperitioneal injection of naloxone. These results support the proposal that : the analgesia produced by morphine microinjected into the NRM is mediated by the activation of spinally projecting serotonergic neuron.

플라즈마 용사법에 의한 지르코니아 5층 열장벽 피막의 고온마모 물성 및 접착강도에 관한 연구

한주철,송요승,이구현 한국항공대학교 1997 論文集 Vol.35 No.-

항공기나 자동차 에진의 내열 보호피막으로써 주목받아온 Thermal Barrier Coating(TBC)은 그 사용 영역이 디젤 엔진의 실린더 헤드나 피스톤 크라운 등으로 확대됨에 따라 고온에서의 내마모성능 또한 중요성이 커지고 있는 실정이다. 따라서 본 연구에서는 경사기능성 5층 지르코니아 열장벽의 미세구조를 비롯 고온 내마모성능, 부착강도를 시험하여 비교 평가하였다. TBC는 최상단에 100%세라믹의 단열층, 그 이하 75:25, 50:50, 25:75의 비율로 세라믹과 결합금속이 혼합된 3개의 경사기능성 중간층, 그리고 모재 직상에 피막과 모재와의 결합을 도모하기위한 100% 금속의 결합층 등, 총 5개층으로 구성하여 고온에서 발생할 수 있는 열응력을 최소화하고자 하였다. 세라믹 단열재로는 YSZ, MSZ 분말을, 결합금속으로는 NiCrAlY, Inconel 625 SUS 316을 사용하였다. 고온마모시험 결과, YSZ/NiCrAlY TBC가 600℃와 800℃에서 가장 우수한 내마모성능을 보여주었고, 400℃에서는 YSZ/Inconel TBC가 가장 적은 마모량을 나타내었다. 특히, YSZ/ NiCrAlY와 MSZ/NiCrAlY TBC의 경우, 600℃와 800℃의 마모량보다 400℃에서의 마모량이 적었으며, 이는 지르코니아의 저온열화현상에 의한 결과라 사료된다. The Thermal Barrier Coating(TBC) has been used to improve the heat barrier and wear resistant properties of the aircraft engine and the automobile engine in high temperature. Especially, the high temperature tribological properties of the cylinder head and the piston crown of diesel engine was emphasized. Therefore, the purpose of this work was to evaluate the micro structure, tribological property in high temperature and bonding strength of five layers functional gradient TBC for the application of TBC. The five layers were composed with 100% ceramic insulating layer, 75(ceramic):25(metal) layer, 50:50 layer, 25:75 layer and 100% metal bonding layer to reduce the thermal stress. The YSZ and MSZ powders were the insulation ceramics powders. The NiCrAlY, Inconel and SUS powders were the bonding and mixing powders for plasma spra process. According to the result of high temperature wear test, the wear resistance of YSZ/NiCrAlY system was most outstanding at 600 and 800℃. At 400℃, the wear resistance of YSZ/Inconel system was better than others. The amount of wear volume loss of YSZ/ NiCrAlY and MSZ/NiCrAlY TBC at 400℃ were much more than the amount of wear volume loss at other temperature because of the low temperature degradation. The bonding strength of TSZ/ NiCRAlY and YSZ/Inconel 5 layers system is better than others.

소세포 폐암의 갑상선전이 1예

장리라,최영식,박요한,문대성,김자경,김성은,최인수,유찬희,남성진 고신대학교 의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.3

Metastasis to the thyroid gland is usually considered uncommon. The most frequent sites of the primary tumor include the kidney, breast and lung. Its presence often indicates poor prognosis. Metastases represent the advanced stage of the tumors and fine needle aspiration cytology is and important way of diagnosis in thyroid metastasis. we experienced a case of Metastatic Small cell Lung Carcinoma to the Thyroid Gland. A 58-year-old man with Graves' disease diagnosed pulmonary nodule in the left upper lung field on his chest X-ray film. The patient's thyroid gland was diffusely swollen, and elastic to hard. A thyroid ultrasonography showed 1cm sized hypodense nodule on the left thyroid gland. The patient underwent a ultrasonography guided fine needle aspiration cytology of the mass. Cytological diagnosis was a metastatic small cell carcinoma. Then Chemotherapy was administered to the patient. The authors report this rare case of metastatic small cell lung carcinoma to the thyroid with literature review.

[Abstracts] The Change of International Politico-Economy and East Asia Reginal Cooperation

Lee,Yo Han 고려대학교 아세아문제연구소 2000 亞細亞硏究 Vol.43 No.2

블록비교를 이용한 프렉탈 영상 압축의 계층적 해석에 관한 연구

이주용,서요한 서강정보대학 1999 論文集 Vol.18 No.-

This paper present a model and experimental results, in fractal image compression using quadtree partition. Fractal coding offers superior runtime performance, but suffers from the problem of long search time in the domain block pool. The output of the coder in fractals compression is IFS, and it is using for feature classification to speeding up the coding time. The encoding of IFS that is continuous blocks iteratively recombined. Before, Original image is devide into regular size called the Range block and A domain block size is double of range block. Here domain and range block consist of a collection for small size partition using fractal image compression. Each connected sets of small square image blocks, of which is a neighbor partitioning with a fractal code. They are selected for which except random neighoboring domain and range block on a fitness criterion. This approach showed as compared to quad tree partition.

만성 활동성 간염에 동반된 간소엽의 변화에 대한 조직학적 연구

李重達,朴耀翰,李昌弘 한양대학교 의과대학 1987 한양의대 학술지 Vol.7 No.2

The study of liver biopsy specimens taen from 67 Korean adults with B-viral chronic active hepatitis (CAH) revealed lobular inflammation which was seldom seen in European-American patients. These findings suggested that the morphologic difference may be indicative of the ultimate prognosis and pathogenesis for chronic hepatitis B in Korean. The author reviewed biopsy materials form the 67 patients with CAH and found 24 cases of labourlar inflammation of varying degree (35%). Serum aminotransferases (SGOT/SGPT) and hepatitis B viral markers (HBs Ag, Ab-HBs, Ab-HBc, Hbe Ag, Ab-Hbe) were tested at the time of liver biopsy. In view of pathogenesis of the lobular changes in CAH, correlation between histologic changes, SGOT/SGPT, and hepatitis B viral markers was discussed, and the results led to following conclusions. Lobular changes associated with CAH consisted of ballooning degeneration, acidophilic bodies, and spotty necrosis which were present mainly in the centrilobular zone around the terminal venules. No correlation was noted between the degree of lobular inflammation and piecemeal necrosis. Lobular changes in the severe degree, however, correlated to the corresponding degree of piecemeal necrosis. The severe degree of lobular inflammation corresponded with the value of serum aminotransferases. No correlation was, however, found between the mild degree of lobular changes and serum aminotransferase values. Of 20 CAH cases with lobular changes tested for hepatitis B viral markers, 18 wee positive for HBs Ag and 9 Hbe Ag. These findings were indicative of the high infectivity of the CAH with lobular changes.

북미에서 다이케스팅산업과 그 연구개발 동향

한요섭,이호인 한국주조공학회 2001 한국주조공학회지 Vol.21 No.6

ASEAN+3 형성의 정치경제적 변수와 ASEAN 대응 : ASEAN's Responses

이요한 한국외국어대학교 동남아연구소 2001 東南亞硏究 Vol.- No.10

고등학교 학교생활기록부의 도입.운영에 대한 교사,학부모,학생의 인식

이경렬,권요한 창원대학교 학생생활연구소 1999 학생생활연구 Vol.12 No.-