http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Hu Liangcong,Xie Xudong,Xue Hang,Wang Tiantian,Panayi Adriana C.,Lin Ze,Xiong Yuan,Cao Faqi,Yan Chengcheng,Chen Lang,Cheng Peng,Zha Kangkang,Sun Yun,Liu Guodong,Yu Chenyan,Hu Yiqiang,Tao Ranyang,Zhou 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-
MicroRNAs (miRNAs) broadly regulate normal biological functions of bone and the progression of fracture healing and osteoporosis. Recently, it has been reported that miR-1224-5p in fracture plasma is a potential therapy for osteogenesis. To investigate the roles of miR-1224-5p and the Rap1 signaling pathway in fracture healing and osteoporosis development and progression, we used BMMs, BMSCs, and skull osteoblast precursor cells for in vitro osteogenesis and osteoclastogenesis studies. Osteoblastogenesis and osteoclastogenesis were detected by ALP, ARS, and TRAP staining and bone slice resorption pit assays. The miR-1224-5p target gene was assessed by siRNA-mediated target gene knockdown and luciferase reporter assays. To explore the Rap1 pathway, we performed high-throughput sequencing, western blotting, RT-PCR, chromatin immunoprecipitation assays and immunohistochemical staining. In vivo, bone healing was judged by the cortical femoral defect, cranial bone defect and femoral fracture models. Progression of osteoporosis was evaluated by an ovariectomy model and an aged osteoporosis model. We discovered that the expression of miR-1224-5p was positively correlated with fracture healing progression. Moreover, in vitro, overexpression of miR-1224-5p slowed Rankl-induced osteoclast differentiation and promoted osteoblast differentiation via the Rap1-signaling pathway by targeting ADCY2. In addition, in vivo overexpression of miR-1224-5p significantly promoted fracture healing and ameliorated the progression of osteoporosis caused by estrogen deficiency or aging. Furthermore, knockdown of miRNA-1224-5p inhibited bone regeneration in mice and accelerated the progression of osteoporosis in elderly mice. Taken together, these results identify miR-1224-5p as a key bone osteogenic regulator, which may be a potential therapeutic target for osteoporosis and fracture nonunion.
An Improved Texture Feature Extraction Method for Recognizing Emphysema in CT Images
Peng, Shao-Hu,Nam, Hyun-Do The Korean Institute of IIIuminating and Electrica 2010 조명·전기설비학회논문지 Vol.24 No.11
In this study we propose a new texture feature extraction method based on an estimation of the brightness and structural uniformity of CT images representing the important characteristics for emphysema recognition. The Center-Symmetric Local Binary Pattern (CS-LBP) is first used to combine gray level in order to describe the brightness uniformity characteristics of the CT image. Then the gradient orientation difference is proposed to generate another CS-LBP code combining with gray level to represent the structural uniformity characteristics of the CT image. The usage of the gray level, CS-LBP and gradient orientation differences enables the proposed method to extract rich and distinctive information from the CT images in multiple directions. Experimental results showed that the performance of the proposed method is more stable with respect to sensitivity and specificity when compared with the SGLDM, GLRLM and GLDM. The proposed method outperformed these three conventional methods (SGLDM, GLRLM, and GLDM) 7.85[%], 22.87[%], and 16.67[%] respectively, according to the diagnosis of average accuracy, demonstrated by the Receiver Operating Characteristic (ROC) curves.
( Peng Hu ),( Shu Hou ),( Peng Fei Du ),( Jia Bin Li ),( Ying Ye ) 대한피부과학회 2012 Annals of Dermatology Vol.24 No.2
An 11-month-old male infant was admitted to our hospital with fever, fussiness, poor feeding, vomiting, and tachypnea for two days prior. Physical examination revealed sporadic papules and vesicles occurring on his hands, feet, face, and perianal mucosa. Enterovirus 71 was identified from both throat swab and vesicle fluid using virus isolation techniques. The patient`s heart rate fluctuated in a very narrow range from 180~210/beats/min regardless of his physiologic state. An electrocardiogram showed P-waves buried within or occurring just after regular, narrow, QRS complexes. The patient was diagnosed as having hand, foot, and mouth disease in combination with paroxysmal supraventricular tachycardia (PSVT). The child recovered well with symptomatic treatment, including intravenous administration of acyclovir, glucocorticoids, immunoglobulin, adenosine, and sotalol. PSVT was terminated within 36 hours of hospitalization. The skin lesions became crusted on the third day, and then proceeded to heal spontaneously. Here we report on this unusual case and review the associated literature. (Ann Dermatol 24(2) 200∼202, 2012)
A visual shape descriptor using sectors and shape context of contour lines
Peng, Shao-Hu,Kim, Deok-Hwan,Lee, Seok-Lyong,Chung, Chin-Wan Elsevier 2010 Information sciences Vol.180 No.16
<P><B>Abstract</B></P><P>This paper describes a visual shape descriptor based on the sectors and shape context of contour lines to represent the image local features used for image matching. The proposed descriptor consists of two-component feature vectors. First, the local region is separated into sectors and their gradient magnitude and orientation values are extracted; a feature vector is then constructed from these values. Second, local shape features are obtained using the shape context of contour lines. Another feature vector is then constructed from these contour lines. The proposed approach calculates the local shape feature without needing to consider the edges. This can overcome the difficulty associated with textured images and images with ill-defined edges. The combination of two-component feature vectors makes the proposed descriptor more robust to image scale changes, illumination variations and noise. The proposed visual shape descriptor outperformed other descriptors in terms of the matching accuracy: 14.525% better than SIFT, 21% better than PCA-SIFT, 11.86% better than GLOH, and 25.66% better than the shape context.</P>
Hu, Sheng-Peng,Xu, Cheng-Yan,Zhang, Bao-You,Pei, Yi,Zhen, Liang Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.10
Monodispersed $Bi_2O_2CO_3$ nanoplates with an average width of 320 nm and thicknesses of 50-90 nm were successfully synthesized by a simple solvothermal method in a mixture solution of polyethylene glycol and $H_2O$. The obtained nanoplates were characterized by means of XRD, FT-IR, SEM and TEM. The effect of surfactant sodium dodecyl benzene sulfonate on the morphology of $Bi_2O_2CO_3$ product was investigated. Under simulated solar light irradiation, $Bi_2O_2CO_3$ nanoplates exhibited superior photocatalytic activities towards the degradation of RhB as well as high chemical stability upon cycling photocatalytic test. The nanoplates also showed promising photodegradation ability for eliminating refractory pollutant of phenol. The excellent photocatalytic performance of $Bi_2O_2CO_3$ nanoplates as compared with P25-$TiO_2$ endows them as promising high efficiency photocatalysts.
Peng Yingchuan,Zhao Jun,Sun Yang,Wan Peng,Hu Yanyue,Luo Guanghua,Qin Wenjing,Huang Shuijin 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.2
The ATP-binding cassette (ABC) proteins are involved in trans-cellular transport of substances at inverse con centrations. After ABC genes were discovered to be involved in multidrug resistance in humans, increased attention was paid to the role of insect ABC genes in pesticide resistance. Chilo suppressalis, the most important Lepidopteran pest in rice production, has developed resistance to the insecticide chlorantraniliprole. However, few of the ABC genes that contribute to chlorantraniliprole resistance have been studied. Here, 47 genes encoding ABC transporters were identified, including five CsABCA, seven CsABCB, ten CsABCC, two CsABCD, one CsABCE, three CsABCF, 15 CsABCG, and four CsABCH genes. The expression profiles of these transporter genes were determined in three chlorantraniliprole-resistant strains: R1, R2, and HR, with a resistance ratio of 38.8, 110.4, and 249.6, respectively. CsABCA1, -D2, and -H2 were up-regulated in all resistant strains, and the trend in the transcript levels of all 47 CsABC genes fitted a descending curve from R1 to HR. Unexpectedly, CsABCF1, -G11 and -G12 were significantly down-regulated in HR. These results provide new insights into the roles of ABC transporters in chlorantraniliprole resistance in C. suppressalis.
Hu, Tian-Peng,He, Xiang-Hui,Meng, Zhao-Wei,Jia, Qiang,Tan, Jian,Li, Xue Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.4
Background: The LigaSure vessel sealing system has been proposed to save operation time and reduce intraoperative blood loss for various surgeries. However, its usage for gastric cancer is still controversial. The aim of the present meta-analysis was to compare the effectiveness of LigaSure with conventional surgery in gastrectomy. Materials and Methods: Sources were retrieved from the Cochrane Library, MEDLINE, EMBASE, SCOPUS and Google Scholar until February, 2015. All randomized controlled trials comparing LigaSure with conventional surgery in curative gastric cancer resection were selected. After data extraction, statistics were performed by Review Manager 5.1 software. Results: Three eligible randomized controlled trials were evaluated, with a total of 335 patients. The quality of the included trials was good, yet some methodological and clinical heterogeneity existed. There were no significant differences between the LigaSure and conventional groups in operative time (weighted mean difference [WMD], -22.95 minutes; 95% confidence interval [CI], [-59.75, 13.85]; P = 0.22), blood loss (WMD, -45.8 ml; 95% CI, [-134.5, 42.90]; P = 0.31), nor the incidence of surgical complications (odds ratio, 1.18; 95% CI, [0.68, 2.05]; P = 0.54). But there was a longer duration of hospital stay in LigaSure group (WMD, 1.41 days; 95% CI, [0.14, 2.68]; P = 0.03). Conclusions: All available randomized evidence has been summarized. LigaSure does not confer significant advantage over conventional surgery for curative gastric cancer resection. The usefulness of the device may be limited in gastrectomy. But, more trials are needed for further assessment of the LigaSure system for gastric cancer.
Peng Hu,Yongle Li,C.S. Cai,Haili Liao,G.J. Xu 한국풍공학회 2013 한국풍공학회지 Vol.17 No.1
Modeling an equilibrium atmospheric boundary layer (ABL) in an empty computational domain has routinely been performed with the k-ε turbulence model. However, the research objects of structural wind engineering are bluff bodies, and the SST k-ω turbulence model is more widely used in the numerical simulation of flow around bluff bodies than the k-ε turbulence model. Therefore, to simulate an equilibrium ABL based on the SST k-ω turbulence model, the inlet profiles of the mean wind speed U, turbulence kinetic energy k, and specific dissipation rate ω are proposed, and the source terms for the U, k and ω are derived by satisfying their corresponding transport equations. Based on the proposed inlet profiles, numerical comparative studies with and without considering the source terms are carried out in an empty computational domain, and an actual numerical simulation with a trapezoidal hill is further conducted. It shows that when the source terms are considered, the profiles of U, k and ω are all maintained well along the empty computational domain and the accuracy of the actual numerical simulation is greatly improved. The present study could provide a new methodology for modeling the equilibrium ABL problem and for further CFD simulations with practical value.