갑상선기능저하증 이환견에 대한 치료 증례

김혜원,이선희,임수정,박형진,김태신,송은식,송근호 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2009 動物醫科學硏究誌 Vol.16 No.1

A 10-year-old, male, poodle dog was referred to the Veterinary Medical Teaching Hospital of Chungnam National University because of continuous cough and cardiomegaly. Weight gain, lethargy, unwillingness to exercise and decreased activity was revealed on history. Obesty and alopecia was also observed on physical examination. Hypercholesterolemia and increased ALP was revealed on blood exam. So, evaluation of thyroid gland function was performed and cTSH concentration was increased. tT4 and fT4 concentrations was decreased. Results of a history, physical examination, blood exam, and thyroid gland fuction test support a diagnosis of hypothyroidism. Initial therapy with sodium levothyroxine was indicated. On 32 days after treatment of hypothyroidism, clinical signs was relieved and cTSH concentration was decreased, tT4 and fT4 concenctrations was increased.

흰쥐에서 척수신경 등쪽뿌리 절단후 척수 등쪽뿔의 substance P 및 calcitoningene-related peptide 함유 신경섬유에 대한 면역조직화학적 연구

이원택,이명식,이종은,박경아 대한해부학회 1994 Anatomy & Cell Biology Vol.27 No.3

진행된 원발성 간암의 방사선 치료와 병합된 온열요법

이형식,허원주 동아대학교의과대학 1992 동아의대학술지 Vol.4 No.1

랫드에서 인체 재조합 적혈구 조혈인자, rHuEPO의 13주 정맥투여 아만성독성에 관한 연구

김형식,곽승준,천선아,박현선,한하수,임소영,안미영,김원배,김병문,안병옥,홍성렬,이병무 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

A recombinant human erythropoietin (rHuEPO) was administered intravenously at dosage levels of 0, 100, 500, and 2500 IU/㎏/day for a period of 13 weeks. There were no observed clinical signs and deaths related to treatment in all groups tested. Decreases in body weight gain and food consumption were observed only in males of 2,500 IU/㎏ group after 2 weeks. In hematological parameters, erythrocyte content, hematocrit values and hemoglobin concentration were dose-dependently increased in rHuEPO treated groups. The ratio between kidney weight and whole body weight was significantly increased in females of 500 and 2,500 IU/㎏ groups. The spleen weight was also increased in both sexes of 500 and 2,500 IU/㎏ groups. However, the absolute weight change of other organs was not observed. In histopathological examinations, the renal tubular basophilia was observed only in males and females of 2,500 IU/㎏ groups. From these results, it is concluded that the no-observed adverse effect level(NOAEL) of rHuEPO is 100 IU/㎏ in rats in the present study.

LDPC부호화를 적용한 영상통신시스템설계

최태식,공형윤,최원호 울산대학교 2001 공학연구논문집 Vol.32 No.1

다양한 멀티미디어 통신이 발달함에 따라 채널부호화를 사용하여 오류를 정정하는 기술이 발달되어 왔다. 본 논문에서는 압축영상의 전송에서 LDPC 부호화를 이용하여 영상통신채널에서의 오류를 복원하고, 영상을 재구성할 수 있는 영상통신시스템을 제안한다. 제안된 영상통신시스템은 패리티검사행렬을 사용하여 가장 많은 오류를 발생하는 열과 가장적은 오류를 발생하는 열을 교환하는 방식을 사용하였고, 가우시안 노이즈를 가지는 통신채널의 신호 대 잡음비는 0dB에서 4dB의 범위로 설정하였다. 패리티 검사 행렬이 작은 경우 제시한 교환 방식을 사용하였을 때 사용하지 않은 경우보다 BER 성능이 우수함을 확인하였으며, 영상을 재구성한 경우에도 PSNR 성능이 우수함을 확인할 수 있었다. As a various multimedia communication has been developed, the error correction technique using the coding method was improved. In this paper, an image communication system using the LDPC decoding method for restoring the error and reconstructing the image in the image compression transmission is proposed. The proposed system has a parity check matrix that can alternate the least occurring error column with the most occurring error column. The signal to noise ratio of a communication channel with the gaussian noise was determined the range between 0dB 4dB. When a parity check matrix was a small size, the system's BER efficiency with the parity check alternating method was better than the parity check without it. Also in reconstructing image, the proposed system's PSNR efficiency was superior to system without alternating method.

總輸膽管 結紮術후 Hepatic Glycogen 變化에 관한 形態學的 硏究

李亨周,李永浩,朴景蘭,金源式 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.1

For the study on the changes of hepatic glycogen after common bile duct ligation, Sprague -Dawley rats (b.w. 250± 20gm, male) were used as experimental animal. In expermental group, at 3hrs, 6hrs, 9hrs, 12hrs, 24hrs, 48hrs, 72hrs, 96hrs, and 120hrs after ligation, the common bile duct at the point of about 1cm proximal portion from its duodenal opening, the liver specimens were collected under ether anesthesia. Simple laparotomy was performed in control rats. After fixation, the specimens were sectioned 5㎛ thickness and stained with Periodic Acid Schiff, and observed under light microscope. Also, transmission electron microscopic photos were obtained with H-7000(Hitachi Co.) TEM. The results were as followings: 1. PAS reactions were changed into negative 6hours after common bile duct ligation. 2. Glycogen depletion after common bile duct ligation was closely related with functional lobule, but not in simple laparotomized rats. 3. In the common bile duct ligated rats, PAS negativity continued in the zone I until 120hours after ligation.

O-Cresolsulfonphthalein 誘導체 混合物의 Complementary Tristimulus Colorimetry에 依한 同時定量

崔遠馨,金忠植 慶星大學校 1981 부산수산대학 논문집 Vol.2 No.1

Application of Complementary tristimulus colorimetry to the simultaneous quantitative analysis of cresolsulfon-phthalein derivatives. The simultaneous quantitative analysis by the spectrophotometry of C. T. S method of the mixture which contains o-cresolsulfon-phthalein derivatives B.C.S.P and C.S.P shows that it is possible only in the dilute acidic solution. In Particular, this method is not in need of the procese of the separation and isolation of substances from their mixture. So it has wide appfication to industrial use as well as organic synthesis. In the present experiment the relative error stays within 1.8%. This results shows satisfactory agreement with those obtained by a mathematical calculations.

골격형 Ⅲ급 부정교합자의 경추와 수완부 골 성숙도에 관한 연구

이진형,양원식 대한치과교정학회 1990 대한치과교정학회지 Vol.20 No.1

This study was undertaken to investigate the interrelationships between the degrees of skeletal maturity of cervical vertebrae and the hand-and-wrist in skeletal Class Ⅲ malocclusions. In 185 skeletal Class Ⅲ malocclusions (male 62, female 123) having the lateral cephalogram and hand-wrist radiogram which were taken on the same day, 6 skeletal maturity stages of cervical vertebrae were compared with 11 skeletal maturity indicators of the hand-and-wrist. On the basis of findings of this study, the following results were obtained: 1. The stages of cervical vertebral maturity are one of the methods possible to assess the individual maturity. 2. Mean ages of male and female were obtained in each cervical vertebral stage. 3. Cervical vertebral stages 1 and 2 are considered to the accelerative growth phase, cervical vertebral stages 3 and 4 are corresponded to the peak height velocity, and cervical vertebral stages 5 and 6 were observed to occur during the decelerative phase of growth after peak height velocity in both sexes. 4. In cervical vertebral stages 1, 2, 3, 4, and 5, the degrees of skeletal maturity of cervical vertebrae in males were more retarded than females. 5. There was the high correlation between the degrees of skeletal maturity of cervical vertebrae and hand-and-wrist.

3-차원 블록인터리버기법의 터보코드를 이용한 영상통신시스템설계

최태식,공형윤,최원호 울산대학교 2001 공학연구논문집 Vol.32 No.1

본 논문에서는 3-차원 블록인터리버기법의 터보코드를 사용하여 무선 통신 환경 하에서 효과적으로 전송할 수 있는 영상 통신 시스템을 제안한다. 웨이브릿 변환과 벡터양자화를 영상의 압축알고리즘에 사용하였으며, 무선통신시스템의 코딩방식 중 하나인 터보코드를 사용하여 압축영상데이터의 통신에 사용하였다. 터보코드의 성능은 데이터율, 부호기의 구속장의 길이, 복호 방식, 순환복호의 횟수, 인터리버의 종류 및 블록크기에 의존되어 진다. 같은 비트 크기에서의 2차원 블록인터리버보다 비트간의 거리를 크게 하는 3차원 인터리빙알고리즘을 적용한 시스템이 영상통신에서 높은 성능을 얻었다. 컴퓨터 시뮬레이션을 이용하여 3차원 블록인터리버의 성능을 압축된 영상과 가우시안 잡음 채널 환경 하에서 비교분석 하였다. In this paper, an image communication system that can effectively work in wireless communication environment is proposed. The wavelet transform and the vector quantization are used to the compress images. The turbo code that is one of the coding methods in wireless communication is used for the compressed image data communication. The efficiency of turbo code depends on the data rate, the constraint length, the decoding algorithm, the number of decoding iteration, the type of interleavers and the block size. The system with 3-D interleaving algorithm whose bit distance is longer than the 2-D block interleaver in the same size had the higher performance in image transmission. To verify the performance of the proposed method, computer simulation was performed in Gaussian noise model.

다발성 대장암 간전이 환자의 간절제를 위한 새로운 시도

주종우,김형철,임철완,신응진,조규석,유기원,송옥평,홍대식,박성진,조준희,이혜경,김희경,권계원,고은석 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Multiple bilobar liver matastases (MBLM) are the main cause of low resectability in the colon cancer liver metastases. The authors experienced one case of initially non-resectable colon cancer liver metastases. He was curatively and safely treated with a two-stage hepatectomy using the new method of future remnant liver volume growing. A 54-year-old man was referred to our department with the sigmoid colon cancer combined with MBLM, which were checked in two small metastatic lesions in the left lobe and five large sized lesions in the right lobe in the computed tomogram (CT). A laparoscopic assisted anterior resection was primarily performed. We performed the 1^(st) stage hepatectomy 3 weeks after the colon resection. Intra-operative Ultrasonogram (US) found 9 small superficial metastatic lesions in the left lobe. All that lesions were completely removed by non-anatomical wedge resection. An occlusion ballon catheter was placed in the right portal vein through a small branch of the inferior mesenteric vein at that time. The future remnant liver volume was sufficiently increased 3 weeks after the 1^(st) hepatectomy. A right hepatectomy was safely performed 22 days after the 1^(st) hepatectomy. The patient received a regional chemotherapy (interleukin2 based immuno-chemotherapy through hepatic artery) for 4 months, then received 9 cycles of systemic chemotherapy (biweekly Oxaliplation, leucovorin, plus 5-fluorouracil) without any recurrence evidence.