적외선 흡수 분광법에 의한 담석 분석 - 육안적 담석 분석과의 비교를 중심으로 -

이영철 ( Young Cheol Lee ),김동건 ( Dong Kun Kim ),김성 ( Sung Kim ),정경석 ( Kyung Suk Chung ),우영민 ( Young Min Woo ),김주섭 ( Joo Seop Kim ),조마해 ( Ma Hae Cho ),정봉화 ( Bong Wha Chung ) 대한소화기학회 1994 대한소화기학회지 Vol.26 No.5

N/A Among the various analytic methods of gallstones, infrared spectroscopy has gained popu- larity because of its benefits. Authors analysed 109 cases of gallstone by qualitative infrared spectroscopy and compared them with classification by visual inspection. Coincidence rate be- tween visual and infrared spectroscopic classification was 78% in four boardmen of general surgery and 64.9% in six residents. There was no difference between two groups(p>0.05). The stones classified as pure cholesterol stone by infrared spectroscopy were interpreted as all types of cholesterol stone by visual inspection. Sometimes it was difficult to differentiate calci- um bilirubinate stone frorn black pigment stone by both visual and infrared spectroscopic clas- sification, and it was not possible to differentiate calcium palmitate stone from calcium bilirubinate stone by visual inspection. While all stones containing calcium phosphate by infra- red spectroscopy were interpreted as black pigment stone by visual inspection, stones contain- ing calcium carbonate were interpreted as several types of gallstone. In conclusion, gallstone analysis by visual inspection alone is not perfect, so it is necessary to study and educate accurate interpretation of gallstone by visual inspection and other analysing methods of gallstone including infrared spectroscopy.(Korean J Gastroenterol 1994; 26: 850 858)

Clinical Application of Near-Infrared Spectroscopy in Neonates

전가원 대한신생아학회 2019 Neonatal medicine Vol.26 No.3

The incidence of cerebral palsy has not decreased despite advances in neonatal care. Preterm infants are at a high risk of cerebral palsy. Moreover, preterm infants might experience permanent neurological sequelae due to injury in the preterm brain. Although the etiology of preterm brain injury is not fully understood, preterm brain injury is strongly associated with abnormal cerebral perfusion and oxygenation. Monitoring systemic blood pressure or arterial oxygen saturation using pulse oximetry is not enough to guarantee proper cerebral perfusion or oxygenation. Early detection of improper cerebral perfusion can prevent irreversible cerebral damage. To decrease brain injury through the early detection of under-perfusion and deoxygenation, other diagnostic modalities are needed. Near-infrared spectroscopy can continuously and noninvasively monitor regional oxygen saturation (rSO2), which reflects the perfusion and oxygenation status of tissues at bedside. Near-infrared spectroscopy represents a balance between tissue oxygen supply and demand. Cerebral rSO2 monitoring has been used most frequently in neonatal cardiac surgery to monitor cerebral oxygenation and prevent hypoxic damage or shock. Recently, cerebral, renal, or splanchnic rSO2 in neonates is frequently monitored. The progression of a disease, brain injury, and death can be prevented by detecting changes in rSO2 values using near-infrared spectroscopy. In this article, the basic principles, usefulness, and applications of near-infrared spectroscopy in neonates are discussed.

Analysis of Carbonization Behavior of Hydrochar Produced by Hydrothermal Carbonization of Lignin and Development of a Prediction Model for Carbonization Degree Using Near-Infrared Spectroscopy(열수 탄화 공정을 거친 리그닌 하이드로차(hydrochar)의 탄화 거동 분석과 근적외선 분광법을 이용한 예측 모델 개발)

( Un Taek Hwang ),( Junsoo Bae ),( Taekyeong Lee ),( Sung-yun Hwang ),( Jong-chan Kim ),( Jinseok Park ),( In-gyu Choi ),( Hyo Won Kwak ),( Sung-wook Hwang ),( Hwanmyeong Yeo ) 한국목재공학회 2021 목재공학 Vol.49 No.3

In this paper, we investigated the carbonization characteristics of lignin hydrochar prepared by hydrothermal carbonization and established a model for predicting the carbonization degree using near-infrared spectroscopy and partial least squares regression. The carbon content of the hydrothermally carbonized lignin at the temperature of 200 ℃ was higher by approximately 3 wt% than that of the untreated sample, and the carbon content tended to gradually increase as the heating time increased. Hydrothermal carbonization made lignin more carbon-intensive and more homogeneous by eliminating the microparticles. The discriminant and predictive models using near-infrared spectroscopy and partial least squares regression approppriately determined whether hydrothermal carbonization has been applied and predicted the carbon content of hydrothermal carbonized lignin with high accuracy. In this study, we confirmed that we can quickly and nondestructively predict the carbonization characteristics of lignin hydrochar manufactured by hydrothermal carbonization using a partial least squares regression model combined with near-infrared spectroscopy. 본 논문에서는 열수 탄화(hydrothermal carbonization)에 의해 제조된 리그닌 하이드로차의 탄화 특성을 조사하였고, 근적외선 분광법과 부분 최소 제곱(partial least squares) 회귀를 이용하여 탄화 거동을 예측하기 위한 모델을 수립하였다. 온도 200℃에서 열수 탄화된 리그닌의 탄소 함량은 무처리 시료 보다 약 3 wt% 높았으며 가열 시간이 증가할수록 탄소 함량도 서서히 증가하는 경향이 나타났다. 열수 탄화는 리그닌을 더욱 탄소 집약적으로 변화시키고 마이크로 파티클을 제거하여 더욱 균질한 특성을 부여하였다. 근적외선 분광법과 부분 최소 제곱 회귀를 이용한 판별 및 예측 모델은 수열 탄화의 적용 여부를 완벽히 구분했으며 높은 정확도로 열수 탄화 리그닌의 탄소 함량을 예측하였다. 본 연구로부터 근적외선 분광법과 결합된 부분 최소 제곱 회귀 모델을 이용하여 열수 탄화에 의해 제조된 리그닌 하이드로차의 탄화 특성을 빠르고 비파괴적으로 예측할 수 있다는 것이 확인되었다.

Comparative nondestructive measurement of corn seed viability using Fourier transform near-infrared (FT-NIR) and Raman spectroscopy

Ambrose, A.,Lohumi, S.,Lee, W.H.,Cho, B.K. Elsevier Sequoia 2016 Sensors and actuators. B Chemical Vol.224 No.-

The commercialization of agriculture has driven the need to ascertain the quality of agricultural inputs, especially seeds in order to optimize output and increase economic returns. Seed viability is a critical consideration for ensuring a reasonably high harvest. More often than not, farmers experience losses after a significant percentage of seeds fail to germinate after planting. The loss of seed viability may be due to a number of reasons such as overheating during drying, physical damage during post-harvest processing, and ageing during storage. It is therefore critical for seed companies to sufficiently inspect their products and uphold them to acceptable seed quality standards in order to gain credibility and ensure business sustainability. In this study, the Fourier transform near-infrared (FT-NIR) and Raman spectroscopy techniques were used for evaluating seed viability to investigate their comparative advantages with regard to the corn viability test and classification. The techniques were applied to white, yellow, and purple corns with 300 samples in each category. The 300 sample corn seeds were divided into two groups of 150 seeds each; one group was heat-treated using microwaving, and the other was used as the control. Sample spectra from treated and untreated corn seeds were collected using an FT-NIR spectrometer in the wave range of 1000-2500nm, and then Raman spectrometer in the wave range of 170-3200cm<SUP>-1</SUP>. The collected spectra were divided into training and testing sets, corresponding to 70% and 30% of the total, respectively for calibration and validation of the techniques. Principal component analysis (PCA) and partial least squares-discriminant analysis (PLS-DA) were used to assess the spectral data from FT-NIR and Raman spectroscopy. The analysis results indicated that FT-NIR spectroscopy correctly classified viable and nonviable seeds for all the three categories of corns with a high accuracy of 100% and a predictive ability of more than 95%. Moreover, Raman spectroscopy demonstrated reasonably high classification accuracy with PLS-DA, but a significant number of seeds were overlapping when using PCA. In addition, an analysis of variance (ANOVA) indicated that the difference between treated and untreated corn seeds was not statistically significant (P<0.05). The study demonstrated that FT-NIR spectroscopy is superior to Raman spectroscopy in evaluating corn seed viability.

식품 산업에서의 근적외선 분광법을 이용한 비파괴 분석법 동향

박종락 한국식품과학회 2022 식품과학과 산업 Vol.55 No.1

Near-infrared spectroscopy (NIRS) is one of the representative non-destructive and eco-friendly analysis methods used for rapid analysis of various ingredients in the food industry. To develop analysis model with NIRS, Chemometrics are applied after pre-treatment of spectrum. Many studies have been reviewed on the analysis of general and functional components for agricultural and livestock products. In the case of livestock products, some studies have been conducted for on-line analysis. This study investigated results on various samples and component applying near-infrared spectroscopy. Furthermore, the results according to sample condition were compared. It was confirmed that NIRS is applied to various fields in the food industry.

원적외선 영역에서 MAPbI3, MAPbBr3 에 대한 분광학적 연구

임재승,박상헌,서유성,이명훈,황정식 한국물리학회 2020 새물리 Vol.70 No.10

MAPbX3, is an organic-inorganic perovskite material system which can be applied in various areas such as magneto-optical data storage, solar cells, lasers, LEDs, etc. MAPbI3 and MAPbBr3 are known to undergo a cubic-to-tetragonal transition at temperatures of about 327 K and 220 K and a tetragonal-to-orthorhombic transition at about 150 K and 145 K, respectively. The transmittance spectra of pallet samples are measured in the far-infrared (FIR) region at various temperatures from room temperature to 80 K by using a Fourier transform infrared (FTIR) spectroscopy-type Bruker Vertex 80v spectrometer. The absorption coefficients are obtained and fitted by using the Drude-Lorentz model to obtain other optical constants including the electric permittivity, optical conductivity, and extinction coefficient. Then, the optical conductivity is fitted to obtain the position and damping coefficient of the longitudinal optical (LO) and the transverse optical (TO) phonons for the sample materials, which are used to calculate the electron-phonon coupling constants, polaron mass, and polaron radii. 페로브스카이트 구조를 가진 MAPbI3 는 유기물과 무기물이 혼합된 물질로 광-자기 데이터 보관장치, 태양전지, 레이저, LED 등 다양한 방면에 활용될 여지가 있는 물질이다. MAPbI3 과 MAPbBr3 각각 약 327 K와 220 K에서 입방격자에서 정방격자로의 전이, 150 K와 145 K에서 정방격자에서입방정계격자로의 구조전이가 일어난다고 알려져 있다. 시료 단결정을 분쇄하여 제작된 시료 펠릿을푸리에 변환 적외선 분광타입의 Bruker Vertex 80v 분광기를 사용하여 상온에서부터 80 K까지 온도를낮춰가며 원적외선 영역에서 투과율을 측정하였다. 흡수 계수를 Drude-Lorentz 모델을 이용한 피팅을수행하여 유전율, 광학전도도와 흡광계수를 포함한 광학상수를 얻었으며, 다시 얻은 광학적 전도도를피팅하여 샘플 물질의 LO와 TO 포논의 위치와 감쇠계수를 얻고, 해당 값을 이용해 전자-포논 결합상수와폴라론 질량, 폴라론 반지름을 얻었다.

Infrared spectroscopy characterization of normal and lung cancer cells originated from epithelium

So Yeong Lee,Kyong-Ah Yoon,장수화,Erdene Ochir Ganbold,Dembereldorj Uuriintuya,Sang-Mo Shin,류판동,주상우 대한수의학회 2009 JOURNAL OF VETERINARY SCIENCE Vol.10 No.4

The vibrational spectral differences of normal and lung cancer cells were studied for the development of effective cancer cell screening by means of attenuated total reflection infrared spectroscopy. The phosphate monoester symmetric stretching νs(PO32-) band intensity at ∼970 cm-1 and the phosphodiester symmetric stretching νs(PO2-) band intensity at ∼1,085 cm-1 in nucleic acids and phospholipids appeared to be significantly strengthened in lung cancer cells with respect to the other vibrational bands compared to normal cells. This finding suggests that more extensive phosphorylation occur in cancer cells. These results demonstrate that lung cancer cells may be prescreened using infrared spectroscopy tools.

Study of molecular structure change of <small>D</small>- and <small>L</small>-glucose by proton irradiation using terahertz spectroscopy

Lee, Kyumin,Jeoung, Kiyoung,Lee, Dong-Kyu,Ji, Young Bin,Seo, Minah,Huh, Yong-Min,Suh, Jin-Suck,Oh, Seung Jae Elsevier 2018 Infrared physics & technology Vol.93 No.-

<P><B>Abstract</B></P> <P>We investigated molecular structure change of <SMALL>D</SMALL>- and <SMALL>L</SMALL>-glucose by proton beam irradiation of 7.8 MeV, using terahertz time-domain spectroscopy. Both glucose pellets exposed to the irradiation of 10<SUP>13</SUP>, 4 × 10<SUP>13</SUP>, 6 × 10<SUP>13</SUP>, and 8 × 10<SUP>13</SUP> particles/cm<SUP>2</SUP> of the particle’s fluence, were characterized using complex refractive indices in terahertz frequency region. We found that fingerprints of two types of glucose in terahertz frequency were disappeared above 8 × 10<SUP>13</SUP> particles/cm<SUP>2</SUP>. Crystallinity breaking and molecular structure change by proton irradiation was reaffirmed using X-ray diffraction (XRD) and Fourier transform infrared (FTIR) spectroscopy.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The structural changes of biochemical molecules by proton beams were measured the terahertz spectroscopy. </LI> <LI> The changes of molecular structure of glucose were investigated by FTIR and XRD method. </LI> </UL> </P>

Infrared Spectroscopy, X-ray Diffraction and Neutron Diffraction Study of BaFe$_{\text{12}\bm{-x}}$Al$_{\bm{x}}$O$_\text{19}$ Solid Solutions

R. E. Huseynov,A. I. Mammadov,R. Z. Mehdiyeva,A. V. Trukhanov,S. V. Trukhanov,V. A. Turchenko,T. P. Hoang,N.T. Dang,S. H. Jabarov 한국물리학회 2019 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.74 No.6

The influences of Al doping on the structural, magnetic and dynamical properties of BaFe$_{12-x}$Al$_x$O$_{19}$ solid solutions ($x = 0.1$--1.2) have been studied by using a combination of X-ray diffraction, neutron diffraction and infrared spectroscopy. The magnetic moment of every Fe atom, including combinations, has been defined, and the magnetic moment of Fe$^{3+}$ ions was found to decrease as the concentration of Al$^{3+}$ diamagnetic ions in the combinations increased. Studies carried out by using infrared spectroscopy showed that four oscillations under normal conditions in these combinations. The results obtained by using infrared spectroscopy for BaFe$_{12-x}$Al$_x$O$_{19}$ combinations were compared with the results obtained by using Raman spectroscopy.

적외선 흡수 분광법에 의한 간내 담석의 성분 분석

김영호(Young Ho Kim),윤용범(Yong Bum Yoon),최규완(Kyoo Wan Choi),김정룡(Chung Yong Kim),김용태(Yong Tae Kim) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.1

N/A Intrahepatic calculi are stones involving the right and left hepatic ducts, and their branches, peripheral to their junction at the hepatic hilum. The incidence of intrahepatic calculi is high throughout East Asia including Korea compaired with the West and the composition of intrahepatic calculi are different from each other in the different geographic areas. Therefore the analysis for the composition of intrahepatic calculi is important to understand the pathophysiology of intrahepatic calculi. However, there is no available data regarding the composition of intrahepatic calculi in Korea. So, we analyzed the compositions of 49 intrahepatic calculi removed through the T-tubes or PTBD tubes by infrared absorption spectroscopy. The principal component of intrahepatic calculi was calcium bilirubinate (48.1%), followed by calcium palmitate (12.5%) and cholesterol (11.1%). Neither calcium carbonate or calcium phosphate was found. The 28.5% of dry weight was not analyzed by infrared absorption spectroscopy. Among the 49 cases, 46 cases were pigment stones and 3 cases were cholesterol stones. By the analysis of the principal component, 45 cases were calcium bilirubinate stones, 3 cases were cholesterol stones and 1 case was a calcium palmitate stone. In conclusion, the major type of intrahepatic calculi in Korea is calcium bilirubinate stone and the presence of cholesterol stones sugested the possibility of dissolution therapy for intrahepatic calculi. Further studies for the unmeasured portion may be required to understand the nature of intrahepatic calculi.