FEM and Experimental Study on Mechanical Property of Integrated Container Building

Yang Zuo,Xiaoxiong Zha 한국강구조학회 2018 International Journal of Steel Structures Vol.18 No.2

Recently, a growing number of the containers have been used in the building structures, therefore, the full size container stiff ness have been studied under the longitudinal load, including the 20 ft container, 40 ft container and the 20 ft combined container. Firstly, the full size container experiment has been studied, and then, the load–displacement curve and loadstress curve have been got. Secondly, based on the nonlinear fi nite element software of Abaqus, the container model has been established and analyzed. By comparing with the load–displacement curves and load-stress values of experiment, the fi nite element model has been verifi ed. Finally, based on the verifi ed fi nite element model, the parametric analysis of the corrugated sheeting size, corrugated sheeting cross section, elasticity modulus of top side beam, and every sheeting action for container stiff ness has been given, and the design advice of single and combined container has been given. The research results have made feasible in design and construction of container buildings and provided some references to corresponding specifi cation preparation.

Structure and electrical properties of Pr6O11-doped CaCu3Ti4O12 NTC ceramics

Zuo Yang,Tian Jian,Tian Yuxin,Miao Guangtan,Fu Peng 한국세라믹학회 2023 한국세라믹학회지 Vol.60 No.3

The xPr6O11–(1 − x)CaCu3Ti4O12 (CCTO) ceramics with perovskite structure were prepared by the solid-state reaction method. The effects of Pr 6O11 addition on the microstructure and electrical properties of the CCTO ceramics were studied. The addition of Pr 6O11 promoted the sintering of CCTO ceramics, and the mean grain sizes increased gradually from 2.13 to 5.08 μm with increasing Pr 6O11 content. All the samples had noticeable negative temperature coefficient (NTC) effect, and both the grain and grain boundary effects contributed to their NTC characteristics. The thermistor characteristic parameter B25/75 decreased from 6883 to 5291 K as Pr 6O11 contents increased from 0.00 to 0.08. The analysis shows that the conductivity of Pr 6O11–CCTO ceramics arises mainly from the electron hopping transport mechanism. The GB resistances are noticeably higher than grain resistances at the same Pr 6O11 content. All the samples showed electrical relaxation behavior. The above observations indicate that the structures and electrical properties of CCTO ceramics can be attuned precisely by adjusting the Pr 6O11 concentration.

FEM and Experimental Study on Mechanical Property of Container Building with Holes

Yang Zuo,Xiaoxiong Zha 한국강구조학회 2017 International Journal of Steel Structures Vol.17 No.1

Based on the finite element simulation and the experimental verification, the stiffness of container building with holes is studied. Firstly, through finite element software of the Abaqus, 20ft and 40ft container model are established, and the corresponding holes and stiffening members are considered. Through simulation, the stiffness and Mises stress contour of the container model are got. Secondly, a full size experiment of container with holes is studied, and then, through comparison of the loading-displacement curves and the loading-stress curves with finite element simulation, the finite element model is verified. Finally, based on the verified finite element model, the influence laws of the hole and the stiffening member is given, and the relevant design recommendations of the hole position, the hole area, the hole size ratio and the stiffening member form are given. Research results make feasible in design and construction of the container buildings and provide some references to the corresponding specification preparation.

Parkinson’s Disease with Fatigue: Clinical Characteristics and Potential Mechanisms Relevant to α-Synuclein Oligomer

Li-Jun Zuo,Shu-Yang Yu,Fang Wang,Yanghui Xia,Ying-Shan Piao,Yang Du,Teng-Hong Lian,Rui-Dan Wang,Qiu-Jin Yu,Ya-Jie Wang,Xiao-Min Wang,Piu Chan,Sheng-Di Chen,Yongjun Wang,Wei Zhang 대한신경과학회 2016 Journal of Clinical Neurology Vol.12 No.2

Background and Purpose The aim of this study was to identify the clinical characteristics and potential mechanisms relevant to pathological proteins in Parkinson’s disease (PD) patients who experience fatigue. Methods PD patients (n=102) were evaluated using a fatigue severity scale and scales for motor and nonmotor symptoms. The levels of three pathological proteins—α-synuclein oligomer, β-amyloid (Aβ)1-42, and tau—were measured in 102 cerebrospinal fluid (CSF) samples from these PD patients. Linear regression analyses were performed between fatigue score and the CSF levels of the above-listed pathological proteins in PD patients. Results The frequency of fatigue in the PD patients was 62.75%. The fatigue group had worse motor symptoms and anxiety, depression, and autonomic dysfunction. The CSF level of α-synuclein oligomer was higher and that of Aβ1-42 was lower in the fatigue group than in the non-fatigue group. In multiple linear regression analyses, fatigue severity was significantly and positively correlated with the α-synuclein oligomer level in the CSF of PD patients, after adjusting for confounders. Conclusions PD patients experience a high frequency of fatigue. PD patients with fatigue have worse motor and part nonmotor symptoms. Fatigue in PD patients is associated with an increased α-synuclein oligomer level in the CSF

RNA m5C modification upregulates E2F1 expression in a manner dependent on YBX1 phase separation and promotes tumor progression in ovarian cancer

Liu Xiaoyi,Wei Qinglv,Yang Chenyue,Zhao Hongyan,Xu Jie,Mobet Youchaou,Luo Qingya,Yang Dan,Zuo Xinzhao,Chen Ningxuan,Yang Yu,Li Li,Wang Wei,Yu Jianhua,Xu Jing,Liu Tao,Yi Ping 생화학분자생물학회 2024 Experimental and molecular medicine Vol.56 No.-

5-Methylcytosine (m5C) is a common RNA modification that modulates gene expression at the posttranscriptional level, but the crosstalk between m5C RNA modification and biomolecule condensation, as well as transcription factor-mediated transcriptional regulation, in ovarian cancer, is poorly understood. In this study, we revealed that the RNA methyltransferase NSUN2 facilitates mRNA m5C modification and forms a positive feedback regulatory loop with the transcription factor E2F1 in ovarian cancer. Specifically, NSUN2 promotes m5C modification of E2F1 mRNA and increases its stability, and E2F1 binds to the NSUN2 promoter, subsequently reciprocally activating NSUN2 transcription. The RNA binding protein YBX1 functions as the m5C reader and is involved in NSUN2-mediated E2F1 regulation. m5C modification promotes YBX1 phase separation, which upregulates E2F1 expression. In ovarian cancer, NSUN2 and YBX1 are amplified and upregulated, and higher expression of NSUN2 and YBX1 predicts a worse prognosis for ovarian cancer patients. Moreover, E2F1 transcriptionally regulates the expression of the oncogenes MYBL2 and RAD54L, driving ovarian cancer progression. Thus, our study delineates a NSUN2-E2F1-NSUN2 loop regulated by m5C modification in a manner dependent on YBX1 phase separation, and this previously unidentified pathway could be a promising target for ovarian cancer treatment.

Full-length cDNA, Expression Pattern and Association Analysis of the Porcine FHL3 Gene

Zuo, Bo,Xiong, YuanZhu,Yang, Hua,Wang, Jun Asian Australasian Association of Animal Productio 2007 Animal Bioscience Vol.20 No.10

Four-and-a-half LIM-only protein 3 (FHL3) is a member of the LIM protein superfamily and can participate in mediating protein-protein interaction by binding one another through their LIM domains. In this study, the 5'- and 3'- cDNA ends were characterized by RACE (Rapid Amplification of the cDNA Ends) methodology in combination with in silico cloning based on the partial cDNA sequence obtained. Bioinformatics analysis showed FHL3 protein contained four LIM domains and four LIM zinc-binding domains. In silico mapping assigned this gene to the gene cluster MTF1-INPP5B-SF3A3-FHL3-CGI-94 on pig chromosome 6 where several QTL affecting intramuscular fat and eye muscle area had previously been identified. Transcription of the FHL3 gene was detected in spleen, liver, kidney, small intestine, skeletal muscle, fat and stomach, with the greatest expression in skeletal muscle. The A/G polymorphism in exon II was significantly associated with birth weight, average daily gain before weaning, drip loss rate, water holding capacity and intramuscular fat in a Landrace-derived pig population. Together, the present study provided the useful information for further studies to determine the roles of FHL3 gene in the regulation of skeletal muscle cell growth and differentiation in pigs.

The Influence of Construction Scheme of Asymmetric Three-Cabin Utility Tunnelling on the Surface Settlement Behaviour

Zuo Chun Li,Gui He Wang,Jun Wei Hao,Yao Zhou,Xiao Yang Wang,Heng Xuan,Feng Huang 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.9

The asymmetric three-cabin structure is one of the favourite choices in urban utility tunnel engineering, as it can provide a higher space utilization and clearer classification for pipelines. However, few work has been done on utility tunnel in such special cross-section during undercutting construction until now. Besides, as the loose soil layers such as sand and silt are often encountered during the utility tunnelling, its influence on surface settlement become one of the main concerns. This study focuses on the influence of the construction scheme on the surface settlement details for an asymmetric three-cabin utility tunnel. A 3D finite element method (FEM) model was established including both the stratum and a utility tunnel based on the Beijing Daxing International Airport (BDIA) Expressway Urban Utility Tunnel project. With this model, the behaviour of the surface settlement with the undercutting construction of the utility tunnel was investigated, and the causes and values of surface settlement in five construction stages were analyzed. By changing the construction spacing and sequence of mid and side cabins, the surface settlement and structural deformation were compared. The numerical results demonstrated a strong correlation between the cross-section shape and surface settlement characteristics. And the symmetry line of the surface settlement trough was offset by 1 m to the side with the larger cross-section. The second (excavation of upper bench in mid-cabin) and fourth (excavation of upper bench in side-cabin) stages caused the largest surface settlement, which were 41.9% and 18.07% of the total settlement, respectively. In addition, after optimizing the field tunnelling scheme, the surface settlement was reduced by 31.9% using the side-tunnel first construction sequence. The proposed numerical model is able to predict the settlement characteristics in each construction stage, which is important and provides a basis for further studies on the surface settlement mechanism and optimal design of the asymmetric three-cabin utility tunnelling scheme.

Haptic tele-driving of wheeled mobile robot over the internet via PSPM approach: theory and experiment

Yang, Hyunsoo,Zuo, Zhiyuan,Lee, Dongjun Informa UK (TaylorFrancis) 2018 Advanced robotics Vol.32 No.13

Nonlinear boundary parameter identification of bridges based on temperature-induced strains

Zuo-Cai Wang,Guo-Peng Zha,Wei-Xin Ren,Ke Hu,Hao Yang 국제구조공학회 2018 Structural Engineering and Mechanics, An Int'l Jou Vol.68 No.5

Temperature-induced responses, such as strains and displacements, are related to the boundary conditions. Therefore, it is required to determine the boundary conditions to establish a reliable bridge model for temperature-induced responses analysis. Particularly, bridge bearings usually present nonlinear behavior with an increase in load, and the nonlinear boundary conditions cause significant effect on temperature-induced responses. In this paper, the bridge nonlinear boundary conditions were simulated as bilinear translational or rotational springs, and the boundary parameters of the bilinear springs were identified based on the measured temperature-induced responses. First of all, the temperature-induced responses of a simply support beam with nonlinear translational and rotational springs subjected to various temperature loads were analyzed. The simulated temperature-induced strains and displacements were assumed as measured data. To identify the nonlinear translational and rotational boundary parameters of the bridge, the objective function based on the temperature-induced responses is then created, and the nonlinear boundary parameters were further identified by using the nonlinear least squares optimization algorithm. Then, a beam structure with nonlinear translational and rotational springs was simulated as a numerical example, and the nonlinear boundary parameters were identified based on the proposed method. The numerical results show that the proposed method can effectively identify the parameters of the nonlinear boundary conditions. Finally, the boundary parameters of a real arch bridge were identified based on the measured strain data and the proposed method. Since the bearings of the real bridge do not perform nonlinear behavior, only the linear boundary parameters of the bridge model were identified. Based on the bridge model and the identified boundary conditions, the temperature-induced strains were recalculated to compare with the measured strain data. The recalculated temperature-induced strains are in a good agreement with the real measured data.

Preparation and Photoelectrocatalytic Performance Study of Au-RGO/TiO2 NTs Photoelectrode

Zuo Jin Long,ShaoDong Yang,YiWen Li,Chong Tan,Zhi Xia,SiYing Yuan,ShiYou Yu,JunSheng Li 한국고분자학회 2022 Macromolecular Research Vol.30 No.11

In our research, The Au-reduced graphene oxide (RGO)/TiO2 nanotubes (NTs) photoelectrode was prepared by electrodeposition, and was characterized and analyzed by scanning electron microscope, X-ray energy scattering spectroscopy, X-ray diffraction, photoluminescence spectroscopy, and photoelectrochemical methods. The results show that the best preparation conditions is setting deposition voltage as 0.2 V and deposition time as 30 s. At the same time, the nano-gold is well supported on RGO/TiO2 NTs without changing the original nanotube array structure. After a 35 W mercury lamp and a 15 V bias are applied, the photoelectric degradation efficiency of methylene blue is 72%, slightly higher thanthose of the other two electrodes. which show demonstrate that the photocatalytic activity of Au-RGO/TiO2 NTs photoelectrodes under visible light is improved effectively.