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Wide-Tunable Mid Infrared Intra-cavity Optical Parametric Oscillator Based on Multi-period MgO:PPLN
Xiao-Chan Wang,Yu-Heng Wang,Hao Zheng,Hong-Zhi Liu,Yong-Ji Yu,Zi-Jian Wang 한국광학회 2021 Current Optics and Photonics Vol.5 No.1
This paper reports a tunable diode-pumped folded intracavity Q-switched singly resonant optical parametric oscillator based on multi-period MgO:PPLN. A wide tuning mid-infrared parametric lightfrom 2.78 μm to 4.17 μm was obtained in real time by changing the poled periods and temperatures. The maximum output power of 1.89 W at 3.2 μm, 1.53 W at 3.5 μm, 0.87 W at 3.8 μm and 0.486 W at 4.1 μm were achieved. The highest optical-optical conversion efficiency was 7.89%. During experiments, a range tunable output of 2.78–4.17 μm in the mid-infrared range was achieved.
Tissue distribution of sialic acid-linked influenza virus receptors in beagle dogs
Zhang-Yong Ning,Xin-Tao Wu,Yan-Fen Cheng,Wen-Bao Qi,Yu-Fu An,Heng Wang,Gui-Hong Zhang,Shou-Jun Li 대한수의학회 2012 Journal of Veterinary Science Vol.13 No.3
Reports of influenza A virus infections in dogs has received considerable attention from veterinarians, virologists, and epidemiologists. Interaction between influenza viral hemagglutinin and cell oligosaccharides containing sialic acid residues results in infection. Sialic acids have an α-2,3-linkage to the penultimate galactose in the avian influenza virus receptor and an α-2,6-linkage in the human receptor. To date,there are no detailed data on the tissue distribution or histological features of either type of sialic acid-linked influenza virus receptors in beagle dogs, which are common laboratory animals and pets. We conducted the current study to visualize the in situ tissue distribution of both sialic acid-linked influenza virus receptors in various organs of beagle dogs using Maackia amurensis lectin II and Sambucus nigra agglutinin. Both α-2,3- and α-2,6-sialic acid-linked receptors were detected in the endothelial cells of the respiratory tract and other organs. Endothelial cells of most gastrointestinal organs were negative for α-2,3-sialic acid-linked receptors in the dogs. Our results suggested that these canine organs may be affected by influenza virus infection. The findings from our study will also help evaluate the occurrence and development of influenza virus infections in dogs.
High Repetition Wavelength-locked 878.6 nm LD Dual-end-pumped Nd:YVO<sub>4</sub> 1064 nm Laser
Li, Yue,Yu, Yong-Ji,Wang, Yu-Heng,Liu, Hang,Liu, He-Yan,Jin, Guang-Yong Optical Society of Korea 2018 Current Optics and Photonics Vol.2 No.6
A $Nd:YVO_4$ laser dual-end-pumped by a wavelength-locked 878.6 nm laser diode is presented. At the repetition rate of 500 KHz, the absorbed pump power of 58 W, an output power of 26.1 W at 1064 nm is obtained, corresponding to an optical-optical efficiency of 45%. The pulse width is 44.2 ns. Meanwhile, the effects of traditional 808 nm pumping and 878.6 nm dual-end-pumping on the output laser beam quality and pulse width are compared and analyzed in an experiment.
Picosecond Mid-Infrared 3.8 μm MgO:PPLN Optical Parametric Oscillator Laser with High Peak Power
Bing-Yan Chen,Yu-Heng Wang,Yong-Ji Yu,Guang-Yong Jin 한국광학회 2021 Current Optics and Photonics Vol.5 No.2
In this study, a compact, picosecond, mid-infrared 3.8 μm MgO:PPLN optical parametric oscillator(OPO) laser output with high peak power is realized using a master oscillator power amplifier (MOPA)1 μm solid-state laser seeded by a picosecond fiber laser as the pump source. The pump source was a 50MHz and 10 ps fiber seed source. After AOM pulse selection and two-stage solid-state amplification, a 1,064 nm laser output with a repetition frequency of 1–2 MHz, pulse width of 9.5 ps, and a maximum average power of 20 W was achieved. Furthermore, a compact short cavity with a unsynchronized pump is adopted through the design of an OPO cavity structure. When the injection pump power was 15 W and the repetition frequency was 1 MHz, the average output power of idler light was 1.19 W, and the corresponding peak power was 119 kW. The optical conversion efficiency was 7.93%. When the repetition frequency was increased to 2 MHz, the average output power of idler light was 1.63 W, the corresponding peak power was 81.5 kW, and the optical conversion efficiency was 10.87%. At the same time, the output wavelength was measured at 3,806 nm, and the beam quality was M X2 = 3.21 and M Y2 = 3.34.
Jie Fan,Tong-da Lei,Meng-Yan Yu,Yong-Heng Wang,Fu-Yuan Cao,Qingqi Yang,Faming Tian,Yong Liu 한국섬유공학회 2020 Fibers and polymers Vol.21 No.2
Keratin, as a promising substitute for tissue engineering due to its excellent biocompatibility and bioactivity, is used to combine one or more other polymers together. However, compound nanofibers with high keratin content (normally>90 wt.%) may result in the poor elongation of nanofiber membranes such as wound dressing. In this work, different ratios of hydroxyapatites (HA) modified by sodium hexametaphosphate were blended with keratin/polyethylene oxide (PEO) spinning solution to produce reinforced keratin blend nanofiber nonwoven membranes as a potential candidate wound dressing. The tensile strength of keratin blend nanofiber membrane with 15 % modified HA addition was two times higher than that without HA. The morphologies and chemical structure of keratin/PEO/HA nanofiber membranes were investigated using SEM, FTIR, and TG. The biocompatibility and the burn repairing performance of keratin/PEO/HA nanofiber mat were also investigated by cell culture and animal burn model. The results showed that the Keratin/PEO/HA nanofiber membranewas beneficial to enhance the proliferation of L929 cell, exhibiting an advantages in reducing inflammatory response in the infective stage and enhancing skin repairing process in the following recover stages. Our data suggested that keratin/PEO/HA nanofiber membrane could serve as a promising burn dressing for treatment of the skin burn.
Tissue-specific expression of the NOD-like receptor protein 3 in BALB/c mice
Zhiqiang Huang,Meng Yu,Shuang Tong,Kun Jia,Rongchang Liu,Heng Wang,Shou-Jun Li,Zhang-Yong Ning 대한수의학회 2014 Journal of Veterinary Science Vol.15 No.2
Activation of the innate immune system requires recognitionof pathogen-associated molecular patterns, such as NOD-likereceptors. The NOD-like receptor protein 3 (NLRP3)inflammasome is involved in induction of the proinflammatorycytokine, IL-1β, and subsequent inflammatoryresponses. NLRP3 inflammasome plays important roles in theinflammatory and innate immune responses associated withautoimmune/inflammatory syndrome. However, analysis of thetissue distribution and expression profiles in BALB/c mice is stillincomplete. In this study, we investigated the tissue distributionand expression pattern of NLRP3 in BALB/c mice to furtherelucidate its function in innate immunity in this commonly usedlaboratory animal model. NLRP3 mRNA expression levels andtissue distribution of the protein were investigated by real-timequantitative PCR and immunohistochemical analyses,respectively. NLRP3 mRNA expression was higher in thekidney and inguinal lymph nodes than in other tissues. Cytoplasmic expression of NLRP3 was detected in the epithelialreticular cells of the spleen and thymus, lymphocytes in theinguinal lymph nodes, cardiac muscle cells, cerebral cortexneurons, alveolar macrophages, renal tubule cells and liversinusoidal endothelial cells. The results of this study will assistinvestigators in interpreting site-specific functions and roles ofNLRP3 in inflammatory responses.
Jung, Chae-Kyun,Lee, Jong-Beom,Kang, Ji-Won,Wang, Xin Heng,Song, Yong Hua The Korean Institute of Electrical Engineers 2004 KIEE International Transactions on Power Engineeri Vol.a4 No.4
Previous research results indicated that the designed current reduction device could effectively reduce the sheath circulating current and that its RDP protection device could shield it against both fault and lightning strokes. In this paper, cable impedance is analyzed using wavelet analysis and distance relay algorithm following the installation of these devices so that the operation of distance relay can be estimated. The test results confirm that in these devices, the fault inception angle and SVL bonding types have no impact on the change of cable impedance. In other words, the conventional distance relay can be used without a new relay setting. Thus we can finally assert that the designed current reduction device and its protection device are effective and can be safely installed on the cable transmission system without disturbance.
Jie Fan,Meng-Yan Yu,Tong-da Lei,Yong-Heng Wang,Fu-Yuan Cao,Xiao Qin,Yong Liu 한국조직공학과 재생의학회 2018 조직공학과 재생의학 Vol.15 No.2
A rapid freezing/lyophilizing/reinforcing process is suggested to fabricate reinforced keratin/hydroxyapatite (HA) scaffold with improved mechanical property and biocompatibility for tissue engineering. The keratin, extracted from human hair, and HA mixture were rapidly frozen with liquid nitrogen and then lyophilized to prepare keratin/HA laminar scaffold. The scaffold was then immersed in PBS for reinforcement treatment, and followed by a second lyophilization to prepare the reinforced keratin/HA scaffold. The morphology, mechanical, chemical, crystal and thermal property of the keratin/HA scaffold were investigated by SEM, FTIR, XRD, DSC, respectively. The results showed that the keratin/HA scaffold had a high porosity of 76.17 ± 3%. The maximum compressive strength and compressive modulus of the reinforced scaffold is 0.778 and 3.3 MPa respectively. Subcutaneous implantation studies in mice showed that in vivo the scaffold was biocompatible since the foreign body reaction seen around the implanted scaffold samples was moderate and became minimal upon increasing implantation time. These results demonstrate that the keratin/HA reinforced scaffold prepared here is promising for biomedical utilization.