http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Registry-based stroke research in Taiwan: past and future
Cheng-Yang Hsieh,Darren Philbert Wu3,,Sheng-Feng Sung 한국역학회 2018 Epidemiology and Health Vol.40 No.-
Stroke registries are observational databases focusing on the clinical information and outcomes of stroke patients. They play an important role in the cycle of quality improvement. Registry data are collected from real-world experiences of stroke care and are suitable for measuring quality of care. By exposing inadequacies in performance measures of stroke care, research from stroke registries has changed how we manage stroke patients in Taiwan. With the success of various quality improvement campaigns, mortality from stroke and recurrence of stroke have decreased in the past decade. After the implementation of a nationwide stroke registry, researchers have been creatively expanding how they use and collect registry data for research. Through the use of the nationwide stroke registry as a common data model, researchers from many hospitals have built their own stroke registries with extended data elements to meet the needs of research. In collaboration with information technology professionals, stroke registry systems have changed from web-based, manual submission systems to automated fill-in systems in some hospitals. Furthermore, record linkage between stroke registries and administrative claims databases or other existing databases has widened the utility of registry data in research. Using stroke registry data as the reference standard, researchers have validated several algorithms for ascertaining the diagnosis of stroke and its risk factors from claims data, and have also developed a claims-based index to estimate stroke severity. By making better use of registry data, we believe that we will provide better care to patients with stroke.
아시아 횡단철도의 경제적 효과 분석 : 중국 동북 3성을 중심으로
구종순,여희정,동무성 한국관세학회 2009 관세학회지 Vol.10 No.1
The paper explores economic effects of the Trans-Asian Railway North Corridor(TAR-NC) in the Northeast regions of China. The 3 Northeast regions, called Dongbeisan Sheng(3 provinces composed of Liaoning Sheng, Helongjiang Sheng, Jilin Sheng) possess natural resources and form a large regional economic block. In the 2000's the Chinese government has led a development policy of land transport via TAR-NC. Volumes transported by rail from origin/destination stations such as Erlianhaote, Suifenhe, Arasankou, Manzhouli are significantly increasing. Furthermore, by the fact that the Russian government plans to reduce railway tariffs and the Chinese government reforms laws related to container transport to increase competitiveness of the TAR-NC as an international railway route, the TAR-NC will offer a better package of services such as transit times, tariffs to attract shippers and compete against well-established shipping lines. Europe is the second export/import trade partner for the 3 Northeast regions. The reduced transit times and tariffs offered by the railway route for land movements of containers will enhance the competitiveness of products of the regions in the European market.
( Cheng Wu ),( Lijie Liu ),( Peng Zhao ),( Dan Tang ),( Dingkang Yao ),( Liang Zhu ),( Zhiqiang Wang ) 대한소화기학회 2015 Gut and Liver Vol.9 No.5
Background/Aims: To screen for serum protein/peptide biomarkers of hepatitis B virus (HBV)-associated chronic hepatic lesions in an attempt to profile the progression of HBV-associated chronic hepatic lesions using surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) techniques. Methods: Using SELDI-TOF MS, serum protein/peptide profiles on the CM10 ProteinChip arrays were obtained from a training group including 26 HBV-associated hepatocellular carcinoma patients with liver cirrhosis (LC), 30 HBV-associated LC patients, 85 patients at different stages of liver fibrosis, and 30 asymptomatic HBV carriers. The most valuable SELDI peak for predicting the progression to LC in HBV-infected patients was identified. Results: A SELDI peak of M/Z 5805 with value for predicting LC in HBV-infected patients was found and was identified as a peptide of the C-terminal fraction of the fibrinogen a-chain precursor, isoform 1. Conclusions: The peptide of the C-terminal fraction of the fibrinogen α-chain precursor, isoform 1 with M/Z 5805, may be a serological biomarker for progression to LC in HBV-infected patients. (Gut Liver 2015;9:665-671)
A BP Neural Network Based on Improved PSO for Increasing Current Efficiency of Copper Electrowinning
Wu Jing,Cheng Yan-Ming,Liu Cheng,Lee Il-Kyoo,Cha Jae-Sang,Huang Wen-Lin 대한전기학회 2021 Journal of Electrical Engineering & Technology Vol.16 No.3
In this paper, to improve the current effi ciency in the copper electrowinning process is taken as the research objective. In the traditional production process, sulfate ion concentration, copper ion concentration and current density are carried out according to the empirical value, which cannot ensure the current effi ciency to reach the optimal level. Therefore, fi rstly, this paper proposes a BP neural network model to improve the current effi ciency according to the relationships between sulfate ion concentration, copper ion concentration, current density and the established BP neural network model is trained by using real data from the enterprise. The simulation results indicate that there is a defi nite error between the predicted current effi ciency and corresponding to the current effi ciency measured at the production site. It is proposed that the BP neural network improved by the improved PSO to further improve the prediction accuracy of the BP neural network. Simulation results indicate that the prediction error of the current effi ciency is greatly reduced that meets the accuracy requirements. On the premise of guaranteeing the quality of copper electrowinning, the current density, sulfate ion concentration and copper ion concentration corresponding to the maximum current effi ciency accurately predicted by this method can be respectively adjusted in real-time in the copper electrowinning process, which realizes the optimization of current effi ciency in the process of copper electrowinning under the background of low carbon and environmental protection.
Non-linear FEA of mechanical properties of modular prefabricated steel-concrete composite joints
Wu Cheng Long,Kan Jian Cheng,Liu Ji Ming,Mou Ben 국제구조공학회 2021 Steel and Composite Structures, An International J Vol.40 No.4
This paper study the seismic performance of modular prefabricated SRC column to steel beam composite joint (MPCJ) under static loading. Numerical modeling of MPCJs with three different beam-end connections was carried out in ABAQUS. Results of the numerical calculation were compared with existing quasi-static test results to verify the feasibility of the numerical model. The model was then used to analyze changes in the moment-rotation relation, failure mode, ductility, stiffness, and bolt stress in the joint between the column and joint module. Besides, stress distributions in the joints were analyzed along different stress paths. Under monotonic loading, the mechanical performance of the MPCJ is significantly affected by the beam end connection mode. Failure of the MPCJ mainly occurs at the beam end connection, thus, the aim of keeping the plastic hinge away from the joint core and preventing shear failure is achieved. Furthermore, the maximum story drift ratio is 3.9–5 times greater than the recommended limit, which indicates good ductility and deformation performance. The MPCJ of the three-beam end connection methods is all semi-rigid connections. The beam end structure will have a large influence on the bolt tension and stress distribution. According to the test research results, a nonlinear model with three parameters including joint cover plate cantilever section length, flange connecting plate thickness and flange connecting plate weld length was established. The theoretical calculation results was consistent with the results of the numerical simulation. MPCJs can be designed based on the proposed theoretical calculation formula.
Wu, Di,Su, Liang-Cheng,Wu, Xiao-Jie,Zhao, Guo-Dong The Korean Institute of Power Electronics 2014 JOURNAL OF POWER ELECTRONICS Vol.14 No.2
An optimized space vector pulse width modulation (SVPWM) method with common mode voltage elimination and neutral point potential balancing is proposed for an open-end winding induction motor. The motor is fed from both of the ends with two neutral point clamped (NPC) three-level inverters. In order to eliminate the common mode voltage of the motor ends and balance the neutral point potential of the DC link, only zero common mode voltage vectors are used and a balancing control factor is gained from calculation in the strategy. In order to improve the harmonic characteristics of the output voltages and currents, the balancing control factor is regulated properly and the theoretical analysis is provided. Simulation and experimental results show that by adopting the proposed method, the common mode voltage can be completely eliminated, the neutral point potential can be accurately balanced and the harmonic performance for the output voltages and currents can be effectively improved.
6-Alkylsalicylic Acid Analogues Inhibit In Vitro ATPase Activity of Heat Shock Protein 90
Cheng-Zhu Wu,An Na Moon,Oksik Choi,Sun-Young Kang,Jung Joon Lee,황방연,김영호,Hong-Sub Lee,홍영수,이동호 대한약학회 2010 Archives of Pharmacal Research Vol.33 No.12
The molecular chaperone heat shock protein 90 (Hsp90) is responsible for maintaining the correct folding and stability of many signaling proteins. It is a promising target of cancer therapeutics and several other diseases, including neurodegenerative disease, nerve injuries, inflammation, and infection. In an effort to identify new Hsp90 inhibitors from natural sources using an in vitro ATPase inhibition assay, two 6-alkylsalicylic acid analogues, salaceyin A and B were identified from the culture extract of Streptomyces. Salaceyin A and B exhibited moderate ATPase inhibitory activities with IC50 values of 68.3 and 65.2 μM, respectively. Binding of salaceyins to human Hsp90α was examined by competition binding experiments with ATPSepharose beads. However, the compounds exhibited no degradation activity of Hsp90 client proteins, Her2, c-Raf, or Akt.