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Woo Hyeonseong,Lee Sanghee,Lee Hyun Sung,Chae Hyun Jun,Jung Jongtak,Song Myung Jin,Lim Sung Yoon,Lee Yeon Joo,Cho Young-Jae,Kim Eu Suk,Kim Hong Bin,Lim Jae-Young,Song Kyoung-Ho,Beom Jaewon 대한의학회 2022 Journal of Korean medical science Vol.37 No.34
Background: This study aimed to investigate the effects of comprehensive rehabilitation management on functional recovery and examine the correlation between clinical parameters and improvements in functional outcomes in severe-to-critical inpatients with coronavirus disease 2019 (COVID-19) in a tertiary hospital. Methods: Post-acute COVID-19 patients who had a World Health Organization (WHO) ordinal scale of 5–7, underwent intensive care, and received comprehensive rehabilitation management, including exercise programs, nutritional support, dysphagia evaluation, and psychological care were included. The appendicular skeletal muscle mass index (SMI), Medical Research Council sum score, handgrip strength, number of repetitions in the 1-minute sit-to-stand test, gait speed, Berg Balance Scale (BBS), and Functional Ambulation Classification (FAC) were evaluated at hospital stay, discharge, and 1-month follow-up. The correlation between the rehabilitation dose and improvement in each outcome measure was analyzed. Results: Overall, 37 patients were enrolled, of whom 59.5% and 32.4% had a score of 6 and 7 on the WHO ordinal scale, respectively. Lengths of stay in the intensive care unit and hospital were 33.6 ± 23.9 and 63.8 ± 36.5 days. Outcome measures revealed significant improvements at discharge and 1-month follow-up. The SMI was significantly increased at the 1-month follow-up (6.13 [5.24–7.76]) compared with that during the hospital stay (5.80 [5.39–7.05]). We identified dose-response associations between the rehabilitation dose and FAC (ρ = 0.46) and BBS (ρ = 0.50) scores. Patients with older age, longer hospitalization, longer stay at the intensive care unit, longer duration of mechanical ventilation, tracheostomy, a more depressive mood, and poorer nutritional status revealed poorer improvement in gait speed at the 1-month follow-up. Conclusion: Comprehensive rehabilitation management effectively improved muscle mass, muscle strength, and physical performance in severe-to-critical COVID-19 patients. Dose-response relationship of rehabilitation and functional improvement emphasizes the importance of intensive post-acute inpatient rehabilitation in COVID-19 survivors.
Preoperative Evaluation of Living Donor Candidate for Liver Transplantation
( Sanghee Song ),( Ok Kyung Kim ),( Myung Eun Lee ),( Jin Yong Choi ),( Hyeyoung Kim ),( Sung-woo Ahn ),( Hyo-sin Kim ),( Kyung Chul Yoon ),( Suk Kyun Hong ),( Nam-joon Yi ),( Kwang-woong Lee ),( Kyun 대한간학회 2016 춘·추계 학술대회 (KASL) Vol.2016 No.1
The downside of living donor liver transplantation, of course, is the risk to the healthy donor. For the donor safety, preoperativeevaluation of donor is important and it should be included psychosocial and ethical issues as well as medical suitability. Here,we introduce a preoperative evaluation of living donor candidate for liver transplantation. Since 2011 our institution`s protocolwas introduced, this three-step evaluation protocol have been used in our center (Fig.1). At Step1, the medical examination ofcandidate for donor by interview includes the medical history, psychosocial circumstance and age; usually 16-60 years. The relationshipbetween the recipient and donor should be within the third degree of consanguinity or an intense emotional relationshipjudged by ethical board of local committee. At Step 2, potential donor undergoes tests two phase medical evaluation, ethicalevaluation and document process. First phase medical evaluation includes basic blood and urine profile, Liver CT scan forgraft/remnant volume of liver, ECG and chest X-ray. Second phase medical evaluation includes viral and neoplastic disease andimaging studies, especially primovist MRI and MRCP, for anatomy and quality of the liver include the degree of fatty change.If necessary, the invasive procedures including liver biopsy and additional consultations required to investigate the potential problemsdiscovered during phases 1 and 2 are done. At Step 3, the multidisciplinary team discuss about donor and decide thedonation. A preoperative liver biopsy was applied to the moderate steatosis from imaging studies. The presence of mild systemicdiseases (e.g., well-controlled hypertension or diabetes) cannot be a contraindication in our protocol. The donors are disciplinedto quit smoking and drinking. The remnant liver volume ≥ 30% of the whole liver is recommended. If macrovesicular steatosisis ≥ 10%, we do liver biopsy and recommend diet control. Donors with a GRWR > 0.8% were generally accepted. Usually minimalanantomical variation of the liver has been accepted. Only candidate who passed these all examination, can be a donor for livertransplantation. This detailed evaluation undoubtedly play a role in our successful living donor liver transplantation program,and there was no donor mortality and the overall donor morbidity was < 6.0%, including 0.9% of major complications (> gradeIII). In conclusion, meticulous donor evaluation is important for the successful LDLT.
임신 중 발견된 크루켄버그 종양의 하지마비를 동반한 골전이
변상희 ( Sanghee Byun ),김현경 ( Hyun Kyung Kim ),김국원 ( Guk Won Kim ),김민정 ( Min Jung Kim ),이해남 ( Hae Nam Lee ),이대우 ( Dae Woo Lee ),김사진 ( Sa Jin Kim ) 대한산부인과학회 2012 Obstetrics & Gynecology Science Vol.55 No.11
Krukenberg tumor is not easy to detect during pregnancy. One reason is its rare incidence because of the chronological gap between the reproductive age and the high risk age for gastric cancer. Another reason is the similarity between the typical symptoms of normal pregnancy and the Krukenberg tumor: epigastric discomfort, early satiety, nausea, etc. We report a case of a pregnant woman in her third trimester who presented with chronic back pain and sudden paraplegia.