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A case of lupus panniculitis triggered by human papillomavirus quadrivalent vaccine injection
( Ju Yeon Choi ),( Jung Yup Kim ),( Sun Min Lim ),( Jae Yun Lim ),( Han Saem Kim ),( Jung In Kim ),( Jung Min ),( Joon Hong Min ),( Young Jun Choi ),( Jae Hui Nam ),( Won Serk Kim ),( Ga Young Lee ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1
Lupus panniculitis usually manifests deep nodules and plaques involving the skin of trunk and proximal extremities, such as the lateral aspects of the upper arms, thighs, and buttocks. Hereditary character and sunlight are well-known predisposing factors. Rarely, lupus panniculitis was exacerbated following anti-hepatitis B vaccination and a lupus profundus like nodule at the site of numerous vaccinations was reported. Also, lupus erythematosus is probably related to trauma induced process, even though the correlation is poor or questionable. We report a case of a 25-year-old woman presenting erythematous patches on the both upper arms and left buttock. She recognized a palpable nodule on an erythematous base on the left upper arm occurred exactly at the site of the first human papillomavirus (HPV) quadrivalent vaccine injection (Gardasil^{®}). Thirty two months later, erythematous to brownish patches were observed on the right upper arm into which the third HPV vaccine was injected and the left buttock. Serum analysis revealed the presence of antinuclear autoantibodies of 1/640. The histologic examination of three cutaneous lesions showed lymphocytic infiltration in the fat lobules and perivascular area, a lymphoid follicle, and loose edematous stroma around fatty lobules consistent with lupus panniculitis. Herein, we report a rare case of lupus panniculitis triggered by HPV vaccination.
Ju Ri Lee,Seung Wan Suh,Ji Won Han,Seonjeong Byun,Soon Jai Kwon,Kyoung Hwan Lee,Kyung Phil Kwak,Bong Jo Kim,김신겸,김정란,Tae Hui Kim,Seung-Ho Ryu,Seok Woo Moon,Joon Hyuk Park,Dong Woo Lee,Jong Chul Youn,D 대한신경정신의학회 2019 PSYCHIATRY INVESTIGATION Vol.16 No.8
Objective We investigated the impact of depressed mood (dysphoria) and loss of interest or pleasure (anhedonia)on the risk of dementia in cognitively-normal elderly individuals. Methods This study included 2,685 cognitively-normal elderly individuals who completed the baseline and 4-year follow-up assessments of the Korean Longitudinal Study on Cognitive Aging and Dementia. We ascertained the presence of dysphoria and anhedonia using the Mini International Neuropsychiatric Inventory. We defined subjective cognitive decline as the presence of subjective cognitive complaints without objective cognitive impairments. We analyzed the association of dysphoria and anhedonia with the risk of cognitive disorders using multinomial logistic regression analysis adjusted for age, sex, education, Cumulative Illness Rating Scale score, Apolipoprotein E genotype, and neuropsychological test performance. Results During the 4-year follow-up period, anhedonia was associated with an approximately twofold higher risk of mild cognitive impairment (OR=2.09, 95% CI=1.20–3.64, p=0.008) and fivefold higher risk of dementia (OR=5.07, 95% CI=1.44–17.92, p=0.012) but was not associated with the risk of subjective cognitive decline. In contrast, dysphoria was associated with an approximately twofold higher risk of subjective cognitive decline (OR=2.06, 95% CI=1.33–3.19, p=0.001) and 1.7-fold higher risk of mild cognitive impairment (OR=1.75, 95% CI=1.00–3.05, p=0.048) but was not associated with the risk of dementia. Conclusion Anhedonia, but not dysphoria, is a risk factor of dementia in cognitively-normal elderly individuals.
Tumescent local anesthetic technique for inguinal hernia repairs
Ju Won Chyung,Dong Gue Shin,Yujin Kwon,Dong Hui Cho,Kyung Bok Lee,Sang Soo Park,Jin Yoon,Yong Seog Jang 대한외과학회 2014 Annals of Surgical Treatment and Research(ASRT) Vol.87 No.6
Purpose: We evaluated the adequacy and feasibility of a tumescent solution containing lidocaine and bupivacaine for inguinal hernia repairs. Methods: The medical records of 146 consecutive inguinal hernia patients with 157 hernia repairs using the tumescent local anesthesia technique performed by a single surgeon between September 2009 and December 2013 were retrospectively reviewed. Results: The mean operation time (±standard deviation) and hospital stay were 64.5 ± 17.6 minutes and 2.7 ±1 .5 days. The postoperative complication rate was 17.8%. There were four cases of recurrences (2.5%) at a mean follow-up of 24 ± 14 months. Conclusion: Our results suggest that local anesthesia with the tumescent technique is an effective and safe modality for inguinal hernia repairs.
A case of oral manifestation of cutaneous lupus erythematosus treated by alitretinoin
( Ju Yeon Choi ),( Jung Yup Kim ),( Sun Min Lim ),( Jae Yun Lim ),( Han Saem Kim ),( Jung In Kim ),( Jung Min ),( Joon Hong Min ),( Young Jun Choi ),( Jae Hui Nam ),( Won Serk Kim ),( Ga Young Lee ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1
Lupus erythematosus is an autoimmune disease with a broad spectrum of skin and multisystemic manifestations. Cutaneous lupus erythematosus (CLE) is referred to the lesions restricted to skin and/or mucous membranes. The prevalence of oral involvement ranges from 9 to 45% in patients with systemic lupus erythematosus and from 3 to 25% in patients with chronic cutaneous involvement. Thus far, antimalarial drugs, dapsone, and retinoids are considered as the first- and second-line treatment medicine in the treatment of CLE. In case of treatment failure or intolerance by the above drugs, vitamin A derivative, alitretinoin was reported as an effective alternative treatment option. We report a case of a 63-year-old woman presenting erythematous eroded plaques on the right buccal mucosa. She was diagnosed as CLE after punch biopsy and received alitretinoin (30 mg daily for 2 days and 10 mg daily for 4 weeks). For 1 month, the patient showed continuous improvement of buccal lesions and finally, the lesions were nearly cleared. She experienced headache and vomiting when she took alitretinoin 30 mg at the first time and those symptoms were disappeared after the dose reduction of alitretinoin. There was no other adverse effect. Herein, we report a case of oral manifestation of CLE treated by alitretinoin and suggest that alitretinoin could be an effective treatment option for CLE.
The Korean Social Life, Health and Aging Project-Health Examination Cohort
Ju-Mi Lee,Won Joon Lee,Hyeon Chang Kim,Wungrak Choi,Jina Lee,Kiho Sung,Sang Hui Chu,Yeong-Ran Park,Yoosik Youm 한국역학회 2014 Epidemiology and Health Vol.36 No.-
The Korean Social Life, Health, and Aging Project (KSHAP) is a population-based longitudinal study of health determinants among elderly Koreans. The target population of the KSHAP are people aged 60 years or older and their spouses living in a rural community of Korea. A complete enumeration survey was conducted in the first wave of the KSHAP on 94.7% (814 of 860) of the target population between December 2011 and July 2012. The KSHAP-Health Examination (KSHAP-HE) cohort consists of 698 people who completed additional health examinations at a public health center (n=533) or at their home (n=165). Face-to-face questionnaires were used to interview participants on their demographics, social network characteristics, medical history, health behaviors, cognitive function, and depression symptoms. Health center examinations included anthropometric measures, body impedance analysis, resting blood pressure measurement, radial artery tonometry, bone densitometry, the timed up-and-go test, and fasting blood analysis. However, only anthropometric measures, blood pressure measurement, and non-fasting blood analysis were available for home health examinations. Collaboration is encouraged and access to the KSHAP baseline data will be available via the website of the Korean Social Science Data Archive (http://www.kossda.or.kr).
A case of symmetric lipomatosis of the tongue
( Ju Yeon Choi ),( Jung Yup Kim ),( Sun Min Lim ),( Jae Yun Lim ),( Han Saem Kim ),( Jung In Kim ),( Jung Min ),( Joon Hong Min ),( Young Jun Choi ),( Jae Hui Nam ),( Ga Young Lee ),( Won Serk Kim ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1
Symmetric lipomatosis of the tongue (SLT) characterizes the symmetric and nonencapsulated lipomas infiltrating muscle fibers. It is an extremely rare condition and considered as different disease from multiple symmetric lipomatosis in affected age, body region, and ethnic group and in the relevance to alcoholism. We report a case of a 56-year-old man presenting multiple symmetric yellowish nodules on both lateral borders of the tongue. There was no pain or discomfort on the tongue. He was a chronic alcoholic and afflicted with pellagra, hypertension, diabetes, and anemia. The histologic examination of the lesion showed mature adipose tissue infiltrating lingual muscles consistent with SLE. He did not want the surgical resection of the lesions. Therefore, lipomas were treated by four times of intralesional injection of triamcinolone (8mg/cc). However, there was no significant change in the size of the lipomas. Herein, we report a rare case of SLT comorbid with pellagra.
A study on Korean women`s skin types by baumann skin type questionnaire
( Ju Yeon Choi ),( Jae Yun Lim ),( Han Saem Kim ),( Jung Min ),( Jung In Kim ),( Hyun Min Seo ),( Sang Hyeon Hwang ),( Young Jun Choi ),( Ho Joo Jung ),( Jae Hui Nam ),( Ga Young Lee ),( Won Serk Kim 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.2
Background: Skin types are various, therefore it is hard to find out them at a glance. To understand them effectively, analysis based on questionnaire could be helpful. Objectives: The purpose of this study is to identify the accuracy and effectiveness of Baumann skin type questionnaire (BSTQ) as compared with an interview with dermatologic specialist. In addition, we aim to find out the difference of skin type proportions according to age and invent a modified BSTQ. Methods: Two-hundred-two women who visited the dermatologic clinic of Kangbuk Samsung hospital, aged 19-64, were enrolled as subjects. They performed both BSTQ and an interview with dermatologic specialist. Modified BSTQ was invented by removing similar and racial questions and adjusting grading scores. Results: The agreement between skin type proportions analyzed by BSTQ and an interview is not reasonable (リ =0.428, 95% CI: 0.363-0.493). There is a weak correlation between the proportion of dryness and age (r=0.208, p<0.01). However, other skin type proportions (sensitivity, pigmentation, and wrinkle) are not significantly correlated with age. Modified BSTQ showed substantial agreement with BSTQ in skin type proportions (リ=0.691, 95% CI: 0.641-0.740). Conclusion: We identified the skin types of Korean women of various ages by BSTQ and an interview. Furthermore, the modified BSTQ might be helpful to recognize skin types concisely.
[FCP 9] A case of non-familial generalized hypotrichosis simplex
( Ju-yeon Choi ),( Junghwa Yang ),( Yun Ho Lee ),( Jung Yup Kim ),( Sunmin Yim ),( Jae Yun Lim ),( Han-saem Kim ),( Joon Hong Min ),( Young Jun Choi ),( Jae-hui Nam ),( Ga-young Lee ),( Won-serk Kim ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1
Hypotrichosis simplex is characterized by scanty or absent hair, which is not associated with ectodermal defects or systemic abnormalities. It is classified according to hereditary transmission, extent of affected area, and degrees of absence of hair. We report a case of an 18-year-old man presenting decreased hair density and woolly hair on the scalp. He recognized decreased hair density when he was 7 years old. There was no hair on the arms, legs, and axillary area. There were scanty hair on the eyebrow and pubic area. There was no family history of hereditary disorders affecting hair. Serum analysis revealed the increased level of dehydroepiandrosterone sulfate and progesterone. Low dose dexamethasone suppression test was negative and abdominopelvic computed tomography showed no adrenal incidentaloma or hyperplasia. The histologic examination of the scalp showed decreased number of hair follicles and mild perifollicular lymphohistiocytic and eosinophilic infiltration. Herein, we report a rare case of non-familial generalized hypotrichosis simplex.
Won, Jun Hui,Oh, Ye Jun,Lee, Ju,Ahn, Han Woong,Lee, Hyung Woo,Cho, Yonho Institute of Electrical and Electronics Engineers 2018 IEEE transactions on applied superconductivity Vol.28 No.3
<P>This paper proposes an algorithm to obtain better results in the integrated control by reflecting the characteristics of the individual control of the front wheel and the rear wheel of tram systems. In the case of the surface transportation, which has recently been introduced, severely curved driving performance is required for the downtown. It is possible to decrease the curve radius and to improve the performance of the straight driving with the individual torque control. Therefore, the individual torque control performance of the motor is the most important point of the surface transportation. The front and rear wheels have different torque characteristics, and the length of the bogie during curve travel also affects these results. This system is more controllable than the system with 1Controller 4Motor (1C4M) in the form of 2C4M with the front and rear wheels being individually controlled, allowing more precise control because of its higher degree of freedom. Because of this individually controlled characteristic, it is possible to control more precisely in the integrated control considering the characteristics of the front wheel and the characteristics of the rear wheel. The validity of the proposed control algorithm is verified by experimental results using a small-scale bogie system.</P>