An adaptive hybrid atom search optimization with particle swarm optimization and its application to optimal no-load PID design of hydro-turbine governor

Zhao Weiguo,Shi Tiancong,Wang Liying,Cao Qingjiao,Zhang Hongfei 한국CDE학회 2021 Journal of computational design and engineering Vol.8 No.5

One metaheuristic algorithm recently introduced is atom search optimization (ASO), inspired by the physical movement of atoms based on the molecular dynamics in nature. ASO displays a unique search ability by employing the interaction force from the potential energy and the constraint force. Despite some successful applications, it still suffers from a local optima stagnation and a low search efficiency. To alleviate these disadvantages, a new adaptive hybridized optimizer named AASOPSO is proposed. In this study, the individual and group cognitive components in particle swarm optimization (PSO) are integrated into ASO to accelerate the exploitation phase, and the acceleration coefficients are introduced to adaptively achieve a good balance between exploration and exploitation. Meanwhile, to improve the search performance of the algorithm, each individual atom possesses its own force constant, which is effectively and adaptively adjusted based on the feedback of the fitness of the atom in some sequential steps. The performance of AASOPSO is evaluated on two sets of benchmark functions compared to the other population-based optimizers to show its effectiveness. Additionally, AASOPSO is applied to the optimal no-load PID design of the hydro-turbine governor. The simulation results reveal that AASOPSO is more successful than its competitors in searching the global optimal PID parameters.

Numerical investigation on the transient characteristics of sediment-laden two-phase flow in a centrifugal pump

Weiguo Zhao,Guoshou Zhao 대한기계학회 2018 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.32 No.1

The objective of this work was to determine pressure fluctuation and transient flow characteristics, which aims to provide references to improve noise and vibration performance for the pump design and optimization when delivering sediment-laden flow. The threedimensional (3D) transient simulations were simulated by SST k-ω turbulence model combined with Homogeneous equilibrium model (HEM). The experimental and numerical data was compared to validate the numerical accuracy. The simulation results predicted that the concentration shows strong effects on the external performance, velocity, pressure, turbulent kinetic energy distribution and peak amplitude of pulsation frequency, which all perform increasing trend with the rise of concentration. Meanwhile, the effect of the diameter size of particles on the flow field was relatively minor, which can also evidently influence the internal flow, but the effect is not simply proportional to the diameter size. The effect of diameter size on silt flow needs to be taken into account associated with the concentration distribution. The dominant frequency of solid-liquid approximately equals 0.8 times that of pure water, and the transient characteristics of sediment-laden flow perform low frequency with high amplitude features.

Transcriptogenic convergence reveals a regulatory network of rice-eating and cooking quality

Weiguo Zhao,Qiang He,Kyu-Won Kim,Sang-Ho Chu,Sang-Kyu Lee,Feifei Xu 한국육종학회 2023 한국육종학회 공동학술발표집 Vol.2023 No.-

Development and use of novel SSR markers for molecular genetic diversity in Italian millet (Setaria italica L.)

Weiguo Zhao,이기안,권순욱,마경호,이명철,박용진 한국유전학회 2012 Genes & Genomics Vol.34 No.1

polymorphic simple sequence repeat (SSR) markers, developed through construction of an SSR-enriched library from genomic DNA of Italian millet (Setaria italica L., P. Beauv.),were used for assessment of molecular genetic diversity against 40 accessions of S. italica. In total, 85 alleles were detected, with an average of 4.5 alleles per locus. The average gene diversity and polymorphism information content (PIC)values were 0.412 and 0.376, ranging from 0.02 to 0.88 and from 0.02 to 0.87, respectively. Values for observed (HO) and expected (HE) heterozygosities ranged from 0 to 0.73 and from 0.03 to 0.89, respectively. Nine loci deviated from Hardy-Weinberg equilibrium. The mean similarity coefficient among accessions was 0.6593. Based on the UPGMA algorithm,six different groups were successfully identified. In this clustering analysis, all Korean accessions grouped in one cluster,indicating that Korean accessions are genetically quite distinct from other introduced accessions. These newly developed microsatellite markers should be very useful tools for several genetic studies, including an assessment of diversity and population structure in Italian millet.

Development of an allele-mining set in rice using a heuristic algorithm and SSR genotype data with least redundancy for the post-genomic era

Zhao, Weiguo,Cho, Gyu-Taek,Ma, Kyung-Ho,Chung, Jong-Wook,Gwag, Jae-Gyun,Park, Yong-Jin Springer-Verlag 2010 Molecular breeding Vol.26 No.4

PREPARATION OF FOLATE-CONJUGATED BOVINE SERUM ALBUMIN NANOPARTICLES ADSORBING EPIRUBICIN HYDROCHLORIDE

XIUHUA ZHAO,JIAMING TANG,YUANGANG ZU,WEIGUO WANG,NA LI,WENJIA XU 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2013 NANO Vol.8 No.6

This work investigated the preparation process of folate-conjugated bovine serum albumin nanoparticles (FA–BSANPs) adsorbing epirubicin hydrochloride (EPI) nanoparticles (FA–EPI–BSANPs), a specific-targeting drug delivery system in cancer chemotherapy. The BSANPs were prepared by desolvation as a drug carrier system and conjugated with folate to produce FA–EPI–BSANPs that specifically target tumors by cross-linking. EPI, an anticancer drug, was adsorbed by this drug carrier system. The influences of six experimental parameters, namely, the adsorption time, FA–BSANPs solution-adsorbed EPI concentration, stirring speed, FA–BSANPs solution pH, the ratio of glutaraldehyde and BSA, and mass ratio of FA–BSANPs to EPI, on the drug loading efficiency (DLR) and drug entrapment efficiency (DER) of FA–EPI–BSANPs were investigated via the single factor method. The results indicated that the optimum operation conditions were obtained with 145.4 nm±0.5 nm MPS, 23.41% DLR and 98.93% DER. The N-hydroxysuccinimide-folate content associated with BSANPs was up to 0.9757% (wt). The DLR and DER of EPI increased with increasing adsorption time, FA–BSANPs solution concentration, and pH value, peaking at 1750 rpm with increasing stirring speed, but decreasing thereafter. The FA–EPI–BSANPs obtained were characterized by laser light scattering, scanning electron microscopy, Fourier transform infrared spectroscopy, differential scanning calorimetry, X-ray diffraction and thermogravimetric analysis. Drug release in vitro was investigated, as well. The characterization results showed that EPI in FA–EPI–BSANPs existed in an amorphous, instead of crystalline state. Most of the EPI was enclosed by FA–BSANPs, and a small amount was adsorbed onto the surface of the FA–BSANPs. The FA–EPI–BSANPs particles are nearly ellipsoidal and significantly affect sustained release. The inhibitory rate of FA–EPI–BSANP was mensurated by MTT method. The inhibitory rate of FA–EPI–BSANPs for SMMC 7721 cell developed with raise of concentration and was higher than other samples. The IC50 values of FA–EPI–BSANPs and EPI were 11.5 μg/mL and 18.8 μg/mL, respectively. The target ability of FA–EPI–BSANP for SMMC 7721 cell was mensurated by fluorescence (FITC) modified albumin techniques. The uptake rate of FA–EPI–BSANPs was higher than samples without folate conjugated, and increased with increased concentration.

A Genome-Wide Association Study Reveals Candidate Genes Related to Salt Tolerance in Rice ( <i>Oryza sativa</i> ) at the Germination Stage

Yu, Jie,Zhao, Weiguo,Tong, Wei,He, Qiang,Yoon, Min-Young,Li, Feng-Peng,Choi, Buung,Heo, Eun-Beom,Kim, Kyu-Won,Park, Yong-Jin MDPI 2018 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.19 No.10

<P>Salt toxicity is the major factor limiting crop productivity in saline soils. In this paper, 295 accessions including a heuristic core set (137 accessions) and 158 bred varieties were re-sequenced and ~1.65 million SNPs/indels were used to perform a genome-wide association study (GWAS) of salt-tolerance-related phenotypes in rice during the germination stage. A total of 12 associated peaks distributed on seven chromosomes using a compressed mixed linear model were detected. Determined by linkage disequilibrium (LD) blocks analysis, we finally obtained a total of 79 candidate genes. By detecting the highly associated variations located inside the genic region that overlapped with the results of LD block analysis, we characterized 17 genes that may contribute to salt tolerance during the seed germination stage. At the same time, we conducted a haplotype analysis of the genes with functional variations together with phenotypic correlation and orthologous sequence analyses. Among these genes, <I>OsMADS31</I>, which is a MADS-box family transcription factor, had a down-regulated expression under the salt condition and it was predicted to be involved in the salt tolerance at the rice germination stage. Our study revealed some novel candidate genes and their substantial natural variations in the rice genome at the germination stage. The GWAS in rice at the germination stage would provide important resources for molecular breeding and functional analysis of the salt tolerance during rice germination.</P>

Famine exposure in early life and type 2 diabetes in adulthood: findings from prospective studies in China

Ning Feng,Zhao Jing,Zhang Lei,Wang Weijing,Sun Xiaohui,Song Xin,Zhang Yanlei,Xin Hualei,Gao Weiguo,Gao Ruqin,Zhang Dongfeng,Pang Zengchang 한국영양학회 2023 Nutrition Research and Practice Vol.17 No.4

BACKGROUND/OBJECTIVES: This study examined the relationship between famine exposure in early life and the risk of type 2 diabetes in adulthood during the 1959–1961 Chinese Famine. SUBJECTS/METHODS: A total of 3,418 individuals aged 35–74 years free of diabetes from two studies in 2006 and 2009 were followed up prospectively in 2009 and 2012, respectively. Famine exposure was classified as unexposed (individuals born in 1962–1978), fetal exposed (individuals born in 1959–1961), child exposed (individuals born in 1949–1958), and adolescent/adult exposed (born in 1931–1948). A logistic regression model was used to assess the relationship between famine exposure and diabetes after adjustment for potential covariates. RESULTS: During a three-year follow-up, the age-adjusted incidence rates of type 2 diabetes were 5.7%, 14.5%, 12.7%, and 17.8% in unexposed, fetal-exposed, child-exposed, and adolescent/adult-exposed groups, respectively (P < 0.01). Relative to the unexposed group, the relative risks (95% confidence inter val) for diabetes were 2.15 (1.29–3.60), 1.53 (0.93– 2.51), and 1.65 (0.75–3.63) in the fetal-exposed, child-exposed, and adolescent/adult-exposed groups, after controlling for potential covariates. The interactions between famine exposure and obesity, education level, and family histor y of diabetes were not obser ved, except for the urbanization type. Individuals living in rural areas with fetal and childhood famine exposure were at a higher risk of type 2 diabetes, with relative risks of 8.79 (1.82–42.54) and 2.33 (1.17–4.65), respectively. CONCLUSIONS: These findings indicate that famine exposure in early life is an independent predictor of type 2 diabetes, particularly in women. Early identification and inter vention may help prevent diabetes in later life.

Research progress and the prospect of CO2 hydrogenation with dielectric barrier discharge plasma technology

Zhang Ziyi,Ding Honglei,Zhou Qi,Pan Weiguo,Qiu Kaina,Mu Xiaotian,Ma Junchi,Zhang Kai,Zhao Yuetong 한국탄소학회 2023 Carbon Letters Vol.33 No.4

In recent years, people are increasingly interested in CO2 hydrogenation to produce value-added chemicals and fuels (CH4, CH3OH, etc.). In the quest for an efficient treatment in CO2 methanation and methanolization, several technologies have been practiced, and DBD plasma technology gain attention due to its easily handling, mild operating conditions, strong activation ability, and high product selectivity. In addition, its reaction mechanism and the effect of packing materials and reaction parameters are still controversial. To address these problems efficiently, a summary of the reaction mechanism is presented. A discussion on plasma-catalyzed CO2 hydrogenation including packing materials, reaction parameters, and optimizing methods is addressed. In this review, the overall status and recent findings in DBD plasma-catalyzed CO2 hydrogenation are presented, and the possible directions of future development are discussed.

Measurement of the interaction enthalpy for mixed micelles of dodecyltrimethylammonium bromide and 1-dodecyl-3- methylimidazolium bromide

Peizhu Zheng,Handi Yin,Jihua Zhao,Weiguo Shen 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.44 No.-

In order to clarify the nature of the inter-micellar interactions, we developed an approach to obtain theintermicellar interaction enthalpy through measuring the mixing heats of dodecyltrimethylammoniumbromide (DTAB)/1-dodecyl-3-methylimidazolium bromide (C12mimBr) mixed micelles by usingflow-mixing calorimetry. It was found that the inter-micellar interaction enthalpies for this system werenegative, representing the attractive enthalpy interactions between the mixed micelle droplets. Theseresults are contradictory to those reported in the literature and interpreted by the predominant attractivedehydration effect of counterion. Static light scattering experiment revealed that the repulsive nature ofthe interaction characterized by the Gibss free energy should be dominated by the entropy interaction.