Si-Schottky障壁型의 大陽電池 製作에 관한 硏究

李相潤,羅炳旭,朴德圭,李鍾德,金奎用,玄東杰,禹洪,盧景錫 慶北大學校 物理化學硏究所 1981 硏究論文集 Vol.1-2 No.-

The characteristics of these Si-schottky barrier type and Heterojunction type solar cells are as follows; 1. SnO_2/n-Si Heterojunction Solar Cells Fabricated by Spray Pyrolysis Method SnO_2 film were deposited on the (100) or (111) surface of Si single crystal by the spray pyrolysis method. The best SnO_2/n-Si solar cell has a good performance, with an open-circult voltage: Voc.=0.45V, short circuit current: Isc.=35.5㎃, fill factor: FF.=0.64, and conversion efficiency: η=10.2% under 98㎽/㎠ irradiation of AMl. The spray pyrolysis described in this paper is simple and suitable for mass production. One possibility for cost reduction lies in this method of junction fabrication, and the idea of simply deposited SnO_2/n-Si junction is, at first sight, very attractive. Hence the SnO_2/n-Si Solar Cell and the effectiveness of this method may be of great value in some future production of low-cost solar cells. 2. In_2O_3: Sn Heterojunction Solar Cells Fabricated by Spray Pyrolitic Method Highly conductive and transparent thin films of In_2O_3: Sn (ITO) are fabricated by spray pyrolytic method. The parameters of these thin films are as follows: resistivity ρ = 1.5×10 exp (-3) Ω·㎝, carrier concentration n = 7.5×10 exp (19) cm^-3, mobility μ = 55.5 ㎠/V·sec and transmission 85-90% over visible and long wave-length region. These thin films have simple cubic system with lattice constant 10.2Å. In_2O_3: Sn/n-Si heterojunction solar cells are fabricated, depositing In_2O_3: Sn (ITO) thin films on n-Si substrates with orientation(100) and resistively 2-3Ω, ㎝ by spray pyrolitic method. Under AMl sunlight simulator, the parameters of the excellent cell obtained has open-circuit voltage Voc=0.52V, short-circuit current I_sc=39.0㎃, fill factor: F.F=0.60 and conversion efficiencyη=12.1%. 3. Al/p-Si MOS Solar Cells Fabricated by Vacuum Evaporation Method Al/p-Si MOS solar cells, consisting of Al on P-tupe silicon with a thin interfacial layer of SiO_2 have been found to have good light conversion efficiency for solar radiation. The effects of the oxide layer thickness between metal and substrate were investigated. Under AMl simulated sunlight illumination the best cell has open circuit voltage Voc=0.50V, short-circuit current I_sc=26.3㎃/㎠, fill-factor FF=0.70 and conversion efficiency η=9.2%. 4. Cr-Cu/P-Si MOS Solar Cells Fabricated by Vacuum Evaporation Method Cr-Cu/p-Si MOS Solar cells, consisting of Cr-Cu on p-type silicon with a thin interfacial layer of SiO_2 have been found to have good light conversion efficiency for solar radiation. The effects of the oxide layer thickness between metal and substrate were investigated. Under AMl simulated sunlight illumination the best cell has open circuit voltage Voc=0.49V, short-circuit current I_sc=26.4㎃, fill-factor: FF=0.72 and conversion efficiency η=9.3%.

2228 COMBINED HYPERMETHYLATION OF APC AND GSTP1 AS A MOLECULAR MARKER FOR PROSTATE CANCER: QUANTITATIVE PYROSEQUENCING ANALYSIS

Kim, Wun-Jae,Ha, Yun-Sok,Yoon, Hyung-Yoon,Min, Byung-Dal,Kim, Won-Tae,Kim, Tong-Wook,Seo, Jeong Won,Kim, Yong-June,Yun, Seok Joong,Lee, Sang-Cheol Williams and Wilkins Co 2012 The Journal of urology Vol.187 No.4

S-545 Risk predictive factors and prevalence of comorbid malignancies in patients with CML

( Tong-yoon Kim ),( Sung-eun Lee ),( Soo-hyun Kim ),( Soo-young Choi ),( Eun-jung Jang ),( Dong-wook Kim ) 대한내과학회 2016 대한내과학회 추계학술발표논문집 Vol.2016 No.1

Introduction: As chronic myeloid leukemia (CML) patents are generally diagnosed at old age and live longer by active use of BCR-ABL1 tyrosine kinase inhibitors (TKIs), the occurrence of other malignancy (OM) is becoming a critical issue as a long-term comorbidity. we reviewed medical records of CML patients and compared with those of age-matched Korean population.Methods: The medical records of 1,469 CML patients who diagnosed between January 2000 and December 2014 were reviewed using Korean data of Asia CML Registry.With a cut-off date of July 2016, age-standardized prevalence rates (A-SPR) of OM (except benign tumors and other leukemias) were analyzed and compared with that of general population in Korea Central Cancer Registry (KCCR). In addition, we analyzed cumulative incidence rate of OM and various risk factors. Results: The median duration of follow-up was 84 (1-197) months, and 96 CML patients had at least one OM. Forty three patients had a history of OM before a median 69 (1-161) months of CML diagnosis and 53 patients developed OM after a median 53 (range; 0.2-172) months of CML diagnosis. A-SPR of OM was 1.7 times higher in CML patients. HL(8.7 times), thyroid ca.(2.6 times), biliary ca.(2.6 times), colorectal ca.(2 times), NHL(1.8 times),cervical cancer (1.8 times), and breast cancer (1.6 times) had a higher A-SPR. With 53 patients who had OM after CML diagnosis, we analyzed the cumulative incidence. Univariate analysis revealed that patients who were more than 37 years old at CML diagnosis(4.3%vs.0.4%, p<0.001) and who had family history of cancer(8.2%vs.2.3%, p=0.002) were associated with a higher OM. Multivariate analysis showed that older age (HR of 4.19, p<0.001) and family history (HR of 3.17, p=0.001) were independently associated with increased risk. There was no difference in 7-year OS between patients with OM (n=96) and without OM (n=1,373) (84.9% vs. 86.9%, p=0.573). However advanced cancer stages (stage 3 and 4) of OM significantly affected poor OS (88.3% vs.65.6% p=0.0406). Conclusions: Although comorbid malignancies did not significantly affect CML survival, poor survival in advanced stages and the high risk of other cancers warn the need of systematic screening in long-term CML survivors

A Locally Acquired Falciparum Malaria via Nosocomial Transmission in Korea

Jung-Yeon Kim,Jeong-Su Kim,Mi-Hyun Park,Young-A Kang,Jun-Wook Kwon,Shin-Hyeong Cho,Byeong-Chul Lee,Tong-Soo Kim,Jong-Koo Lee 대한기생충학열대의학회 2009 The Korean Journal of Parasitology Vol.47 No.3

비전형적인 고형 가유두상 종양

김성훈 ( Seong Hun Kim ),조양동 ( Yang Tong Cho ),권혁진 ( Hyeok Jin Kwon ),안철민 ( Chul Min An ),김인희 ( In Hee Kim ),김상욱 ( Sang Wook Kim ),이수택 ( Soo Teik Lee ),이승옥 ( Seung Ok Lee ) 대한소화기학회 2009 대한소화기학회지 Vol.54 No.4

Solid-psudopapillary tumor is an uncommon pancreatic neoplasm of low malignant potential that most frequently affect young woman. Solid-psudopapillary tumor are histologically, clinically, and prognostically quite distinct from the more common ductal adenocarcinoma. Recently, we experienced a 36-year-old male who was suspected to have extrapancreatic tumor based on atypical radiologic imaging study, young age, and male sex, and finally diagnosed as solid-psudopapillary tumor on immunohistochemical stain examination. We report this case with review of the relevant literatures. (Korean J Gastroenterol 2009;54:252-256)

Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia

Jung, Hye Seung,Chung, Kun Wook,Won Kim, Jeong,Kim, Jin,Komatsu, Masaaki,Tanaka, Keiji,Nguyen, Yen Hoang,Kang, Tong Mook,Yoon, Kun-Ho,Kim, Ji-Won,Jeong, Yeon Taek,Han, Myoung Sook,Lee, Moon-Kyu,Kim, K Elsevier 2008 Cell metabolism Vol.8 No.4

<P><B>Summary</B></P><P>Autophagy is a cellular degradation-recycling system for aggregated proteins and damaged organelles. Although dysregulated autophagy is implicated in various diseases including neurodegeneration, its role in pancreatic β cells and glucose homeostasis has not been described. We produced mice with β cell-specific deletion of <I>Atg7</I> (<I>autophagy-related 7</I>). <I>Atg7</I> mutant mice showed impaired glucose tolerance and decreased serum insulin level. β cell mass and pancreatic insulin content were reduced because of increased apoptosis and decreased proliferation of β cells. Physiological studies showed reduced basal and glucose-stimulated insulin secretion and impaired glucose-induced cytosolic Ca<SUP>2+</SUP> transients in autophagy-deficient β cells. Morphologic analysis revealed accumulation of ubiquitinated protein aggregates colocalized with p62, which was accompanied by mitochondrial swelling, endoplasmic reticulum distension, and vacuolar changes in β cells. These results suggest that autophagy is necessary to maintain structure, mass and function of pancreatic β cells, and its impairment causes insulin deficiency and hyperglycemia because of abnormal turnover and function of cellular organelles.</P>

Development and validation of a comorbidity index for predicting survival outcomes after allogeneic stem cell transplantation in adult patients with acute leukemia: a Korean nationwide cohort study

Sung-Soo Park,Hee-Je Kim,Tong Yoon Kim,Joon yeop Lee,Jong Hyuk Lee,Gi June Min,Silvia Park,Jae-Ho Yoon,Sung-Eun Lee,Byung-Sik Cho,Ki-Seong Eom,Yoo-Jin Kim,Seok Lee,Dong-Wook Kim 대한혈액학회 2021 Blood Research Vol.56 No.3

Background Allogeneic hematopoietic stem cell transplantation (alloSCT) is a potentially curative treatment option for acute leukemia. We aimed to identify the comorbidity factors affecting survival outcomes after alloSCT and develop a new comorbidity index tool for predicting overall survival (OS). Methods A Korean nationwide cohort of 3,809 adults with acute leukemia treated with alloSCT between January 2002 and December 2018 was analyzed as the development cohort. A retrospective cohort comprising 313 consecutive adults with acute leukemia who underwent alloSCT between January 2019 and April 2020 was analyzed as the validation cohort. Results In the development cohort, advanced age, male sex, and comorbidities such as previous non-hematologic malignancy, hypertension, and coronary or cerebral vascular disease were significantly related to poor OS. Subsequently, a new comorbidity scoring system was developed, and risk groups were created, which included the low-risk (score ≤0.17), intermediate-risk (0.17< score ≤0.4), high-risk (0.4< score ≤0.55), and very high-risk (score >0.55) groups. The 1-year OS rates were discriminatively estimated at 73.5%, 66.2%, 61.9%, and 50.9% in the low-risk, intermediate-risk, high-risk, and very high-risk groups in the development cohort, respectively (P<0.001). The developed scoring system yielded discriminatively different 1-year OS rates and 1-year incidence of non-relapse mortality according to the risk group (P=0.085 and P=0.018, respectively). Furthermore, the developed model showed an acceptable performance for predicting 1-year non-relapse mortality with an area under the curve of 0.715. Conclusion The newly developed predictive scoring system could be a simple and reliable tool helping clinicians to assess risk of alloSCT in adults with acute leukemia.

급냉응고된 Al-X 합금의 시효에 따른 상변화

김동훈,박원욱 대한금속재료학회(대한금속학회) 1985 대한금속·재료학회지 Vol.23 No.1

A study has been made on the change of hardness, lattice parameter and thermal stability in Al-X (X=Ti, Zr, V) alloys which were produced by the Atomization-Splat Quenching method. Analysis of diffraction pattern was performed by computer for aging mechanism. In Al-Zr alloy, aging peak is obtained at 400℃ for 1 hour in the Vickers hardness test. Coherent metastable phases are detected by the TEM analysis during aging treatment. For Al-Ti alloy, it is found that the metastable structure is tetragonal (a=12.4-12.6 A, c=13.7-14.3A). When the alloys are heat-treated at 400℃ for 100 hours, the morphologies of precipitates are different each other.

기혼여성 우울증환자의 결혼만족도와 역기능적 태도가 우울에 미치는 영향

김은경,이호택,백주희,이상연,홍종문,이재원,김선무,허통욱 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.4

연구목적 : 결혼 후 우울증이 발생한 기혼 여성환자에게 있어 우울에 미치는 결혼만족도와 역기능적 태도의 중요성을 검증하기 위해 본 연구를 수행하였다. 방 법 : 40명의 기혼여성 우울증환자 및 대조군으로서의 비우울 기혼여성집단 34명에 대해 우울증상의 정도 및 결혼만족도와 역기능적 태도 수준을 평가하기 위해서 각각 BDI(Beck Depression Inventory). DAS(Dysfunctional Attitude Scale). DYAS(Dyadic Adjustment Scale)를 실시하였다. t-test를 통해 결혼만족도와 역기능적 태도 및 각 소척도들에 대한 두 집단간 차이를 비교하였으며, 또한 우울에 영향을 미치는 각 변수들의 상대적 중요성을 예측하기 위해 단계적 중다회귀분석을 실시하였다. 결 과 : 1) 기혼여성 우울환자집단은 기혼여성 비우울집단에 비해 전반적인 결혼만족도가 낮았으며, 부부간의 의견일치도, 부부관계만족도, 응집력 및 애정표현 등 하위요인에서도 만족도가 더 낮았다. 2) 기혼여성 우울환자집단은 기혼여성 비우울집단에 비해 역기능적 태도가 의미있게 높았다. 즉 기혼여성 우울환자는 승인욕구와 완전주의적 특성이 강하며, 자신의 수행을 더욱 부정적으로 평가하는 특징을 지니는 것으로 밝혀졌다. 3) 기혼여성 우울환자집단의 우울을 예측하는 중요한 요인으로 결혼만족도의 하위요인인 부부관계만족도, 역기능적 태도의 하위요인인 승인욕구와 완전주의가 지적되었다. 결 론 : 기혼여성의 경우, 결혼생활의 불만족감이 우울증의 발생 및 유지에 중요한 영향을 끼치며, 그 내재적인 사고과정에서 역기능적 태도가 인지적 취약성 요소로 작용하는 것으로 보인다. 따라서 기혼여성 우울중환자의 역기능적 태도를 효율적이고 건설적인 사고방식으로 변화시킴으로써, 결혼생활의 만족도를 높일 수 있고, 궁극적으로 그들의 우울감을 감소시킬 수 있을 것으로 기대된다. Objectives : This study was designed to examine the effect of marital satisfaction and dysfunctional attitudes on depression in married women. Methods : Forty depressed married female patients and 34 non-depressed women as normal control group completed three self-report questionnaires, Beck Depression Inventory (BDI), Dysfunctional Attitude Scale(DAS), and Dyadic Adjustment Scale(DYAS). Marital satisfaction and dysfunctional attitudes were compared by student t-test between the two groups. Also, relative importances of each variables to depression were examined with stepwise multiple regression analysis. Results : Depressed patients reported significantly lower level of marital satisfaction and showed higher level of dysfunctional attitudes than normal controls. Dyadic satisfaction, approval need, and perfectionism subfactors were more important in predicting depressive symptomatology than other variables in patients. Conclusion : We conclude that marital satisfaction has significant influence on development and maintenance of depression in married women, and in underlying thinking process, dysfunctional attitudes serve as a cognitive vulnerability factor. This conclusion involves the expectation that if dysfunctional attitudes of depressed married women could be changed positively, their marital satisfaction will be increased to higher level and depression will be decreased. Overall, our findings stress that we need to consider the degrees of marital satisfaction and dysfunctional attitudes of depressed maried women, when treating them, in order to individualize treatments and optimize our ability to predict responsiveness to therapy.

연령에 따른 전립선크기의 변화: 충청북도지역의 무작위 역학조사

김동욱,이형래,김원재 大韓泌尿器科學會 1998 Korean Journal of Urology Vol.39 No.8