Acute Pancreatitis Due to a Duodenal Ulcer

Sung Ik Pyeon,Jong Ho Hwang,Yong Tae Kim,Ban Seok Lee,Sang Ho Lee,Jae Nam Lee,Jae Hoon Cheong,Kong Jin Oh 대한소화기내시경학회 2014 Clinical Endoscopy Vol.47 No.6

Duodenal ulcers and acute pancreatitis are two of the most commonly encountered gastrointestinal diseases among the general population. However, duodenal ulcer-induced pancreatitis is very rarely reported worldwide. This report elaborates on a distinct medical treatment that contributes to partial or complete treatment of acute pancreatitis induced by a duodenal ulcer scar.

우연히 발견된 직장의 원발성 소포림프종

편성익 ( Sung Ik Pyeon ),송근암 ( Geun Am Song ),백동훈 ( Dong Hoon Baek ),김광하 ( Gwang Ha Kim ),이봉은 ( Bong Eun Lee ),이성준 ( Seong Jun Lee ),윤정빈 ( Jung Bin Yoon ),한성용 ( Sung Yong Han ),박도윤 ( Do Youn Park ) 대한소화기학회 2017 대한소화기학회지 Vol.69 No.2

The gastrointestinal tract is the most common site of extra-nodal non-Hodgkin lymphoma. However, the incidence of primary rectal lymphoma is extremely rare. Among the primary gastrointestinal lymphomas, follicular lymphoma has been described as a rare disease. It is difficult to diagnose rectal lymphoma due to its variable growth patterns and inadequate biopsies. Majority of patients with rectal lymphoma have non-specific symptoms or negative biopsies, often delaying the diagnosis. Our patient is a 62-year-old female. Two sessile and smooth subepithelial lesions with a yellowish normal mucosa were found on a screening colonoscopy. The initial mucosal biopsy finding was chronic inflammation, but we were highly suspicion of malignancy; we performed an endoscopic mucosal resection. Herein, we present a rare case of rectal follicular lymphoma diagnosed by endoscopic mucosal resection with a literature review. (Korean J Gastroenterol 2017;69:139-142)

The predictors of sustained virological response with sofosbuvir and ribavirin in patients with chronic hepatitis C genotype 2

( Sung Yong Han ),( Hyun Young Woo ),( Jeong Heo ),( Sang Gyu Park ),( Sung Ik Pyeon ),( Young Joo Park ),( Dong Uk Kim ),( Gwang Ha Kim ),( Hyung Hoi Kim ),( Geun Am Song ),( Mong Cho ) 대한내과학회 2021 The Korean Journal of Internal Medicine Vol.36 No.3

Background/Aims: Real-world, clinical practice data are lacking about sofosbuvir/ ribavirin (SOF/RBV) treatment of Korean patients with hepatitis C virus genotype 2 (HCV GT2) infection. This study investigated the efficacy and safety of SOF/RBV in Korean patients with HCV GT2 infection and clinical factors predicting sustained virological response 12 weeks (SVR12) after the end of SOF/RBV treatment. Methods: A total of 181 patients with HCV GT2 with/without cirrhosis were treated with SOF/RBV for 16/12 weeks. Rapid virological response (RVR) was defined as non-detectable HCV RNA at 4 weeks. Results: The RVR rate was 80.7% (146/181), the end of treatment response rate was 97.8% (177/181) and the SVR12 rate was 92.8% (168/181). Of eight patients with relapse, four did not achieve RVR. Three patients had a history of hepatocellular carcinoma (HCC). Multivariable analysis showed that RVR (p = 0.015) and no previous history of HCC (p = 0.007) were associated with SVR12. Factors significantly contributing to RVR included cirrhosis, creatinine concentration, and pre-treatment HCV RNA level. SVR12 rate was significantly higher in RVR (+) than RVR (-) patients (95.2% vs. 82.9%, p = 0.011) and also significantly higher in patients without than with a history of HCC (94.1% vs. 72.7%, p = 0.008). During treatment, 80/181 patients (44.2%) experienced mild to moderate adverse events, with 32 (17.7%) requiring RBV dose reductions due to anemia. Conclusions: SOF/RBV treatment was effective and tolerable in HCV GT2 patients. RVR and no previous history of HCC were positive predictors of SVR12.

투시영상 없이 시행한 췌장 가성낭종의 내시경초음파 유도하 배액술

한성용 ( Sung Yong Han ),김광하 ( Gwang Ha Kim ),편성익 ( Sung Ik Pyeon ),이문원 ( Moon Won Lee ),송병구 ( Byeong Gu Song ),백동훈 ( Dong Hoon Baek ),김동욱 ( Dong Uk Kim ),송근암 ( Geun Am Song ) 대한췌담도학회 2018 대한췌담도학회지 Vol.23 No.1

배경/목적: 췌장 가성 낭종은 급성과 만성 췌장염의 흔한 합병증이다. 내시경 초음파를 통한 배액술은 여러단계와 여러장비들이 필요하다. 모든 병원에서 선형초음파내시경 기계 및 투시영상 검사실을 같이 갖추진 못하고 있다. 우리는 투시영상없이 초음파내시경을 통한 췌장가성낭종의 배액술의 안전성과 효율성을 확인하고자 한다. 방법: 2009년 1월부터 2016년 12월까지 초음파내시경을 통해서 가성낭종의 배액술을 시행한 10명의 환자를 분석하였다. 경위적 접근법을 통하여 시행하였으며, 1개 혹은 2개의 7Fr 이중돼지꼬리 플라스틱 배액관을 사용하여 배액술을 시행하였다. 결과: 기술적 성공률은 100% 이며, 임상적 성공률은 80% 였다. 2명의 환자에서는 내시경적 배액술로성공하지 못하여, 경피부배액술을 시행하였고, 수술적치료 없이 호전되었다. 3명의 환자에서는 합병증이 발생하였다(출혈, 감염, 스텐트 이탈). 평균 36.5개월을 추적관찰하였을때 가성낭종이 재발한 환자는 없었다. 결론: 투시영상없이 초음파내시경을 통한 췌장 가성낭종의 배액술은 췌장가성낭종의 치료에서 안전하고, 기술적으로 가능하며, 효과적인 방법이다. Background/Aims: Pancreatic pseudocyst is a common complication of acute and chronic pancreatitis. Endoscopy ultrasound (EUS)-guided drainage includes multiple steps and requires many resources such as a linear echoendoscope and a fluoroscopy room, which may not be available at all medical centers. We aimed to evaluate the efficacy and safety of EUS-guided pancreatic pseudocyst drainage without fluoroscopy. Methods: This retrospective study analyzed 10 patients who had undergone EUSguided transmural drainage of pancreatic pseudocyst without use of fluoroscopy at the Pusan National University Hospital between January 2009 and December 2016. Drainage was performed via a transgastric approach and one or two 7 Fr double-pigtail stents were inserted. Results: The technical success rate was 100% and the clinical success rate was 80%. In two patients, clinical success was not achieved and additional percutaneous catheter drainage was done. Therefore, pseudocysts in all the patients were treated successfully without surgical drainage. However, there were three adverse events in three patients: bleeding, infection, and stent migration in each respective patient. During the median follow-up period of 36.5 months, there was no recurrence of pseudocysts in any of the patients. Conclusions: EUS-guided transmural drainage of pseudocyst drainage without use of fluoroscopy is a technically feasible, safe, and effective procedure for the treatment of pancreatic pseudocyst. Korean J Pancreas Biliary Tract 2018;23(1):24-31

용종절제술을 시행한 위유암종 치험 1예

박창영,이상종,김병익,편유장,유종현,전우규,김명숙 대한소화기내시경학회 1996 Clinical Endoscopy Vol.16 No.4

Gastric carcinoid tumors were previously believed to be rare lesions, representing less than 2% of all carcinoid tumors and less than 1% of all stomach neoplasms. More recent studies have demonstrated that they may constitute as much as l0-30% of carcinoid tumors. We recently experienced a 35-years old businessman with gastric carcinoid tumor who camplained of postprandial epigastric discomfort. Gastrofiberscope showed protruding mass with central depression and erasion which was located on greater curvature of lower body and its size was 1 x 1 cm. Gastroendoscopic biopsy was per formed. It was identified to carcinoid tumor(Argyrophilic tumor). EUS(endoscopic ultrasonography) revealed that the lesion was limited to submucosa without evidence of any metastasis to adjacent lymph node. The carcinoid tumor was successfully removed by endoscopic polypectomy. Gastrofiberscope and EUS 9months after polypectomy showed that the lesion was nearly normal mucosa without submucosal thickening.

유암종에 대한 임상적 고찰

박창영,이상종,김병익,정을순,김기택,성기철,전경홍,황기은,장남수,편유장 대한소화기학회 1998 대한소화기학회지 Vol.30 No.2

Background/Aims: The term, carcinoid, is derived from $quot;Karznoid$quot; coined by Oherndorfer in 1907, which means carcinoma like lesion with no malignant potential. However, it is now generally accepted that these innocuous neoplasms potentially can produce widespread metastasis. Although the carcinoid tumor is relatieve]y rare, it continue to be of special clinical interest because of the endocrine potential, the malignant potential and the recent appearance of the composite carcinoma-carcinoid tumor. Methods: We reviewed the recorded clinical rnanifestations of twenty-two patients with carcinoid tumor, which had been treated from the Kang Book Samsung Hospital for 17 years frorn August 1979 to Septernher 1996. Results: The peak incidence was in the 5th decade occup- ying 9 cases(42%) and male predominence with a ratio of 2.1:1. The common site of the tumors was the rectum(8 cases) and appendix(5 cases). The incidence ot' carcinoid tumors according to the embryologic origin were foregut 6 cases(27%), midgut 7 cases(32%), hindgut 9 cases(41%). The hepatic metatasis was presented in 3 cases. There was no case with classic carcinoid syndrome. Thirty-two percent cases had carcinoma with carcinoid tumor, and nine percent cases had malignant carcinoid tumor. Conclusions: Comparing the age and tumor location, some difference was observed between 22 cases carcinoid tumor experienced at our hospital and those of foreign studies, but other difference was not observed.