규칙적인 리듬의 청각 자극이 사회불안 감소에 미치는 효과

김수아(Sua Kim1),송현주(Hyunjoo Song) 한국심리치료학회 2021 한국심리치료학회지 Vol.13 No.2

본 연구는 규칙적인 리듬의 청각자극이 사회불안 감소에 효과가 있는지를 알아보고자 하였다. 이를 위해 ‘높은 사회불안 집단’ 22명과 ‘낮은 사회불안 집단’ 20명을 선별한 뒤, 각 집단 내에서 실험군과 통제군을 같은 수로 무선할당 하였다. 구조화된 불안 유도 과제인 TSST-G를 사용하여 불안을 유도한 이후, 실험군에만 5분 간 30bpm 의 메트로놈 자극을 들려주었다. 생리적 증상을 측정하기 위해 실험의 처음부터 끝까지 초 단위로 심장 박동수를 측정하는 기기를 착용하였으며, 각 과제 수행 구간별 심장 박동수 평균을 구하였다. 또한 과제 수행 구간마다 불안과 긴장, 회피감에 대해 100점 만점으로 평정하도록 하였고, 암산 이후, 자극제시/휴식 후, 디브리핑 이후의 세 구간에서는 사후반추사고를 측정하였다. 심장 박동수의 기저선과 사전 평가에서 실시한 발표불안 점수를 공변 량으로 두고 심장 박동수 평균에 대해 반복 측정 공분산 분석을 실시한 결과, 실험군의 심장 박동수가 통계적으로 유의미한 수준으로 안정된 것으로 나타났으며 이러한 효과는 낮은 불안수준 집단에서만 유의하게 나타났다. 결론 적으로 본 연구는 비침습적이고 주변에서 쉽게 구할 수 있는 자극을 이용해 사회 불안을 감소시킬 수 있다는 점에서 의의가 있다. This study was designed to see if the auditory stimulation with metronomic beat were effective in reducing social anxiety. 22 high social anxiety group and 20 low social anxiety groups were selected. 11 assigned test/high social anxiety group, 11 assigned control/high social anxiety group, 10 assigned test/low social anxiety group, 10 assigned control/low social anxiety group. After using the structured anxiety induction task, TSST-G, a 30-bpm metronomic stimulation was given to the test group only for 5 minutes. To measure physiological symptoms, the heart rate was measured every second of the experiment from beginning to the end of the experiment, and the heart rate average was calculated for each section of the task. In addition, anxiety, tension, and avoidance were rated at 100 out of every section interval, and post-event rumination were measured in three sections(after mental arithmetic, stimulation/resting, debriefing). As a result of repeated measures analysis of covariance for the heart rate average, the heart rate of the test group was found to be stable at a statistically significant level, and this effect was significant only in the low anxiety group. Also, the longer the subjects listened to the metronomic beat, the effect was clearer. At this time, the baseline of the heart rate and the speech anxiety scale performed in the pre-evaluation were set as covariate. In conclusion, this study is significant in that it can reduce social anxiety using non-invasive and easily available stimuli.

Seven-day and In-hospital Mortality According to Left and Right Ventricular Dysfunction in Patients With Septic Shock

Sua Kim,Hyeri Seok,Beong Ki Kim,Yu Jin Kim,Seung Heon Lee,Je Hyeong Kim,Yong-Hyun Kim 대한심장학회 2023 Korean Circulation Journal Vol.53 No.12

Background and Objectives: The prognostic implications of septic cardiomyopathy have not been clearly demonstrated. We evaluated serial changes in left ventricular (LV) and right ventricular (RV) function in patients with septic shock and their prognostic value on 7-day and in-hospital mortality. Methods: Transthoracic echocardiography was performed within 48 hours of the diagnosis of septic shock and 7 days after the initial evaluation. In addition to traditional echocardiographic parameters, LV and RV function was evaluated using global longitudinal strain (GLS), and tricuspid annular plane systolic excursion (TAPSE). Results: A total of 162 patients (men, 83, 51.5%; 70.7±13.4 years; Acute Physiology and Chronic Health Evaluation [APACHE] II, 30.6±9.2) were enrolled. Initial GLS and TAPSE were −14.9±5.2% and 16.9±5.5 mm, and improved in the follow-up evaluation (GLS, −17.6±4.9%; TAPSE, 19.2±5.4 mm). Seven-day and in-hospital mortality were 24 (14.9%) and 64 (39.8%). Seven-day mortality was significantly associated with initial GLS >−16% (odds ratio [OR], 14.066, 95% confidence interval [CI], 1.178–167.969, p=0.037) and APACHE II score (OR, 1.196, 95% CI, 1.047–1.365, p=0.008). The in-hospital mortality of 7-day survivors was associated with follow-up TAPSE <16 mm (OR, 10.109, 95% CI, 1.640–62.322, p=0.013) and Sequential Organ Failure Assessment score (OR, 1.340, 95% CI, 1.078–1.667, p=0.008). GLS was not associated with in-hospital mortality of 7-day survivors. Conclusions: Fluctuation of both ventricular function was common in septic shock. Seven-day mortality of patients with septic shock was related to GLS, whereas in-hospital mortality of 7-day survivors was related to TAPSE, not to GLS.

Association between Left Ventricular Systolic Dysfunction and Mortality in Patients with Septic Shock

Sua Kim,Jung-Dong Lee,김병기,Yong Hyun Kim,Je Hyeong Kim 대한의학회 2020 Journal of Korean medical science Vol.35 No.4

Background: The impact of myocardial damage on the prognosis of patients with septic shock is not clearly elucidated because complex hemodynamic changes in sepsis obscure the direct relationship. We evaluated left ventricular (LV) conditions that reflect myocardial damage independently from hemodynamic changes in septic shock and their influence on the prognosis of patients. Methods: We retrospectively enrolled 208 adult patients who were admitted to the intensive care unit and underwent echocardiography within 7 days from the diagnosis of septic shock. Patients who were previously diagnosed with structural heart disease or coronary artery disease were excluded. Left ventricular ejection fraction (LVEF) was divided into four categories: normal, ≥ 50%; mild, ≥ 40%; moderate, ≥ 30%; and severe dysfunction, < 30%. Wall motion impairment was categorized into the following patterns: normal, diffuse, ballooning, and focal. Results: There were 141 patients with normal LVEF. Among patients with impaired LV wall motion, the diffuse pattern was the most common (34 patients), followed by the ballooning pattern (26 patients). Finally, 102 patients died, and in-hospital mortality was significantly higher in patients with severe LV systolic dysfunction (hazard ratio [HR], 1.97; 95% confidence interval [CI], 1.04–3.75; P = 0.039) and in patients with diffuse pattern of LV wall motion impairment (HR, 2.28; 95% CI, 1.19–4.36; P = 0.013) than in those with a normal LV systolic function. Conclusion: Severe LV systolic dysfunction and diffuse pattern of LV wall motion impairment significantly affected in-hospital mortality in patients with septic shock. Conventional echocardiographic evaluation provides adequate information on the development of myocardial damage and accurately predicts the prognosis of patients with septic shock.

생성 AI 기반 뉴스 기사 심리지수를 활용한 부동산 가격 예측 모델

김수아 ( Kim Sua ),권미주 ( Kwon Miju ),조수빈 ( Cho Soobin ),김은수 ( Kim Eunsoo ),김현희 ( Hyon Hee Kim ) 한국정보처리학회 2023 한국정보처리학회 학술대회논문집 Vol.30 No.2

부동산 시장은 다양한 요인에 의해 가격이 결정되며 거시경제 변수뿐 만 아니라 뉴스 기사, SNS 등 다양한 비정형 데이터의 영향을 받는다. 특히 뉴스 기사는 국민들이 느끼는 경제 심리를 반영하고 있어 부동산 가격에 영향을 크게 미치는 변수라고 판단된다. 본 연구에서는 뉴스 기사의 세분화된 감정 분석을 통해 전통적인 분석 방법보다 더 의미 있는 결과를 얻을 수 있는 부동산 가격 예측 모델을 생성하였으며 뉴스 기사로부터 심리 지수를 산출하기 위해 생성 AI 를 활용하였다. 제안하는 매매가격지수 예측 모델을 통해 부동산 시장과 뉴스 기사와의 관계성에 대해 파악할 수 있으며, 사회/경제적 동향을 반영한 부동산 가격 변동을 예측할 수 있을 것으로 보인다.

Suppression of Migration and Invasion by Alnus hirsuta in Human Hepatocellular Carcinoma Cells

김보람(Bo-Ram Kim),성수희(Su Hui Seong),Tae-Su Kim(Tae-Su Kim),김진호(Jin-Ho Kim),서찬(Chan Seo),이하늘(Ha-Nul Lee),임수아(Sua Im),김정은(Jung Eun Kim),정지민(Ji Min Jung),박정업(Jung Up Park),최경민(Kyung-Min Choi),정진우(Jin-Woo J 한국자원식물학회 2023 한국자원식물학회지 Vol.36 No.3

How small is enough for the left heart decompression cannula during extracorporeal membrane oxygenation?

Sua Kim,김진석,Jae Seung Shin,Hong Ju Shin 대한중환자의학회 2019 Acute and Critical Care Vol.34 No.4

Background: Left ventricular (LV) distension is a recognizable problem accompanied by sub-sequent complications during venoarterial extracorporeal membrane oxygenation (VA-EC-MO). However, no gold standard for LV decompression has been established, and no minimal flow requirement has been designated. Thus, we evaluated the efficacy of the 8-Fr Mullins sheath for left heart decompression during VA-ECMO in adult patients. Methods: Left heart decompression was performed when severe pulmonary edema was detected on chest radiography or when no generation of pulse pressure followed severe LV dysfunction in patients receiving VA-ECMO. We punctured the interatrial septum and inserted an 8-Fr Mullins sheath into the left atrium via the femoral vein. The sheath was connected to the venous catheter used for ECMO. The catheter was maintained during VA-ECMO. Results: The left heart decompression procedure was performed in seven of 35 patients who received VA-ECMO between February 2017 and June 2018. Three patients had acute myocardial infarction; three, fulminant myocarditis; and one, dilated cardiomyopathy. Four patients showed noticeable improvement of pulmonary edema within 3 days, and three patients with a pulse pressure of <10 mm Hg showed an increase in pulse pressure of >20 mm Hg within 24 hours from the left heart decompression procedure. All seven patients were successfully weaned from VA-ECMO. No complications related to the left heart decompression procedure occurred. Conclusions: An 8-Fr sheath may be a possible option for left heart decompression in adult patients with LV distension under VA-ECMO who are expecting recovery of LV function.

A 6 Gbps/pin Low-Power Half-Duplex Active Cross-Coupled LVDS Transceiver with Switched Termination

Sua Kim,Bai-Sun Kong,Chilgee Lee,Changhyun Kim,Young-Hyun Jun 한국전자통신연구원 2008 ETRI Journal Vol.30 No.4

A novel linear switched termination active cross-coupled low-voltage differential signaling (LVDS) transceiver operating at 1.5 GHz clock frequency is presented. On the transmitter side, an active cross-coupled linear output driver and a switched termination scheme are applied to achieve high speed with low current. On the receiver side, a shared preamplifier scheme is employed to reduce power consumption. The proposed LVDS transceiver implemented in an 80 nm CMOS process is successfully demonstrated to provide a data rate of 6 Gbps/pin, an output data window of 147 ps peak-to-peak, and a data swing of 196 mV. The power consumption is measured to be 4.2 mW/pin at 1.2 V.

Effects of Increased Uric Acid Intake on the Abundance of Urate-anion Exchanger and Organic Anion Transporter Proteins in the Rat Kidney

( Sua Kim ),( Chang Hwa Lee ),( Chong Myung Kang ),( Gheun Ho Kim ) 대한전해질학회 2007 Electrolytes & Blood Pressure Vol.5 No.2

Renal handling of uric acid mainly occurs in the proximal tubule, and bidirectional transport of urate may involve apical absorption via the urate-anion exchanger (URAT1) and basolateral uptake via organic anion transporters (OAT1 and OAT3). In rat kidneys, we investigated whether the protein abundance of URAT1, OAT1, and OAT3 is affected by the increase in uric acid intake. Male Sprague-Dawley rats were randomly divided into control and uric acid-supplemented groups, and uric acid-supplemented rats were given 1.75 g of uric acid per 180 g body weight per day for 8 days. After the animal experiment, kidneys were harvested and semi-quantitative immunoblotting was carried out from cortical homogenates using polyclonal peptide-derived antibodies to URAT1, OAT1, and OAT3. Serum uric acid level showed an increasing tendency in the uric acid-supplemented rats compared with control rats, whereas urinary uric acid excretion was not significantly different between the uric acid-supplemented rats and control rats. URAT1 protein abundance in cortical homogenates was not significantly different between the uric acid-supplemented rats and control rats. However, OAT1 protein abundance was significantly increased in the uric acid-supplemented rats compared with the control rats. OAT3 protein abundance was not significantly different between the uric acid-supplemented rats and control rats. In conclusion, OAT1 may have a regulatory role in response to the increase in uric acid intake in the rat kidney. The up-regulation of OAT1 would exert stimulation of urinary uric acid excretion and might contribute to protection from hyperuricemia.

Effects of intermittent hydrostatic pressure on cell adhesive forces and other related parameters under various resting periods

Kim, Young Jick,Park, SuA,Lee, Yong Jae,Shin, Ji Won,Kim, Dong-Hwa,Heo, Su-Jin,Park, Ki Dong,Shin, Jung-Woog Wiley Subscription Services, Inc., A Wiley Company 2008 Journal of biomedical materials research. Part B, Vol.b85 No.2

<P>The purpose of this study is to investigate the effects of intermittent hydrostatic pressure with various resting periods on the cell adhesive forces and other parameters related to spreading in early stage of cell adhesion. For this, bovine pulmonary arterial endothelium (CPAE, cell line), porcine articular chondrocytes, and human endothelial cells (HECs) were used. The cells were divided into six different experimental groups. Control group was cultured without stimulation, while the constant pressure was applied to group 1 for 2 h. Groups 2–5 were intermittently pressurized for 2 min at a time over a 2-h period with 5, 10, 15, and 20-min resting periods, respectively. Each group was then split into two subgroups, depending whether it experienced extra 60 min stabilization period after stimulation. The average adhesive force and the number and area of focal contacts were significantly higher in the group 4 subgroup, which received an extra 60 min of culture than in the other groups. Similarly, other parameters in this subgroup were significantly different from those in the other groups. The focal contact area and adhesive force were closely related (r = 0.990). We concluded that the mechanical stimuli affect cell adhesion and that the length of the resting period influences the adhesive forces generated at the early stages of adhesion. © 2007 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2008</P>

Hemodynamic Monitoring

( Sua Kim ) 대한결핵 및 호흡기학회 2020 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.128 No.-