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한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고
양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1
The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.
신현심,정상훈,박동원 東亞大學校 海洋資源硏究所 1994 硏究論文集 Vol.7 No.2
The experimental binodal curve and tie line data were determined for ternary systems of 2-propanol-water with isoamylacetate and 1-butanol as solvents at 25℃. Consistency of the experimental data for several correlations was investigated, the experimental tie line data were correlated with NRTL model and the parameters in NRTL model were estimated and the calculated values of tie lines were predicted.
카드뮴 처리한 인간 폐 섬유아 세포주에서 IL-6의 발현
신동훈 大韓産業醫學會 1996 대한직업환경의학회지 Vol.8 No.1
Cadmium is a highly toxic element responsible for acute and chronic toxicity in man and induces pathophysiological effects by modulating components of immune system. Cytokines are being increasingly recognized as essential mediators of normal and pathologic immune response. The present study has been investigated the effect of cadmium cytotoxicity for lung fibroblast and expression of cytokine gene in unstimulated and cadmium-treated lung fibroblast using reverse transcription-polymerase chain reaction. We showed that cadmium inhibited the cell proliferation and expression of IL-6, TGF-β mRNA in both unstimulated and cadmium-treated cell. The expression of IL-6 mRNA increased at 0.1mM cadmium treated for 24 hours than for 2 hours. This results suggest that cadmium stimulates expression of IL-6 mRNA in lung fibroblast.
신동훈,김경수,김기홍 대한의진균학회 1998 대한의진균학회지 Vol.3 No.2
Background: The incidence and causative dermatophytes of tinea capitis has been changed with time. Objective: The purpose of this study was to investigate the clinical and mycological features of tinea capitis in Taegu. Methods: We evaluated the clinical and mycologic aspects of tinea capitis in 39 patients registered in Yeungnam University Hospital from January 1981 to June 1998. Results and Conclusion: The incidence of tinea capitis was 1.3% of 3,077 total dermatophytoses. The ratio of male to female patients was 1.6:1. Although most of the patients were children under the age of If, adult patients with tinea capitis were 23.1% of the cases. Frontal scalp was the most frequent site of tinea capitis. The most common causative organism of tinea capitis was Microsporum canis. Trichophyton rubrum and Trichophyton verrucosum were isolated, also.
Chalcone 유도체를 도입한 폴리이미드 배향막에서의 광배향 특성
申東明,鄭敬勳 弘益大學校 科學技術硏究所 2000 科學技術硏究論文集 Vol.11 No.-
The conventional rubbing technique can't satisfy recent demands for alignment quality. Therefore the photoalignment with UV light have been investigated. Polyimide (PI) film was used as an alignment layer, The PI film (4wt%) was spin coated 3) and cured. The thickness of the coated PI film was about 50 nm. By Williamson synthesis 4), the coated PI film was modified with the chalcone derivatives, The LPUV light was irradiated on the PI film. A cell was fabricated by injecting LC (BL001) into a pair of substrate. The LPUV light irradiation caused dimerization between the chalcones or isomerization in the chalcone derivatives. The long alkyl-chains were aligned homeotropically to the PI film. Thereby the alignment direction of LC-molecules was homcotropic to the PI film.
간세포암에서 FDG-PET/CT 영상분석에 영향을 미치는 인자
신동훈 고신대학교 의과대학 2009 고신대학교 의과대학 학술지 Vol.24 No.1
Background : This study was performed to evaluate the clinicopathologic features and comparision of correlation factor of FDG uptake on hepatocellular carcinoma(HCC) patients. Methods: We retrospectively studied 61 HCC patients who studied 18[F]FDG-PET at department of surgery of Gospel hospital, Kosin university college of medicine between December 2004 and May 2008. We had analyzed age, sex, etiology of HCC, Child-Pugh classification, serum AFP, size of tumor, number of tumor, CLIP score, histopathologic classification(WHO classification, Edmonson calssification), FDG uptake and PET SUV, retrospectively. Statistical analyses were performed using the cross table Chi-square test and independent sample t-test. Results: FDG uptake was found in 39 patients of 61 HCC patients (63.9%), There were no significant differences except for size of tumor correlation factor of FDG uptake in total HCC patients with regard to sex, Child-Pugh classification, serum AFP, number of tumor, CLIP score and WHO classification. Conclusion: The size of tumor(≥5cm) was a correlation factor of FDG uptake in total HCC patients.
카드뮴과 아연이 사람 단핵구성 세포주(THP-1)에서 IL-6의 분비에 미치는 영향
신동훈,서성일,서석권 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.3
Objectives : This study was performed to investigate effects of cadmium and zinc on IL-6 secretion using human monocyte in a culture system. Methods : We have used trypan blue dye exclusion methods to examine the effect of cytotoxicity of CdCl₂, ZnCl₂in THP-1 cells. IL-6 was measured by the ELISA method in the cell culture supernatants and the expression of IL-6 mRNA was examined by reverse transcription-polymerase chain reaction. Results : IL-6 production by THP-1 cells were decreased at 0.1 mM cadmium concentration (p<0.05) and increased as zinc concentration increased. Zinc prevented cadmium-induced suppression of IL-6, and the addition of a chelating agent, EDTA, restores IL-6 secretion. The expression of IL-6 mRNA decreased at 0.08 mM and 0.1 mM cadmium concentrations. Conclusion : This results suggest that cadmium depressed production and gene expression of IL-6 in stimulated human monocytes, and zinc prevented cadmium-induced suppression of IL-6.