급성 심근경색 후 심인성쇽의 발생에 관여하는 위험인자

전두수(Doo Soo Jeon),정해억(Hae Uk Chung),승기배(Ki Bae Seung),강동헌(Dong Hun Kang),김상우(Sang Wo Kim),김용주(Young Ju Kim),채장성(Jang Sung Chae),김재형(Jae Hyung Kim),홍순조(Soon Jo Hong),최규보(Kyu Bo Choi) 대한내과학회 1996 대한내과학회지 Vol.50 No.6

N/A Objectives: Cardiogenic shock resulting from acute myocardial infarction is a serious complication with high mortality. The early identification of patients at high risk of developing post-infarction cardiogenic shock might allow early intervention in an attempt to prevent cardiogenic shock and to reduce the mortality due to cardiogenic shock. The aim of the present study was to examine the risk factors of inhospital development of cardiogenic shock among patients with acute myocardial infarction. Methods: We studied 152patients with acute myocardial infarction who were admitted to Kang-Nam St. Mary's hospital within 24hours after the onset of chest pain and did not have cardiogenic shack on admission between March 1991 and May 1994. Clinical data of these patients were analyzed. Results: Of 152patients, 17(11.1%) developed cardiogenic shock during their hospital stay. Cardiogenic shock developed in 53% of cases more than 24hours after admission. 82.4% of patients with cardiogenic shock died whereas a 6.7% in-hospital mortality was found among patients without cardiogenic shock. Multivariate regression analysis that controlled for variables affecting incidence of postinfarction cardiogenic shock showed that independent risk factors for in-hospital cardiogenic shock were history of myocardial infarction (adjusted relative odds[RO]=5.294, 95% confidence interval[CI]=2.149 to 13.041); heart failure on admission (RO=3.344, 95% CI=1.738 to 6.432); hyperglycemia (>180mg/dl) in non-diabetic patients (RO=3.270, 95% CI=1,590 to 6.727); age over 70 year old (RO=2.912, 95% CI= 1.816 to 4.668); ST deviation over 4mm (RO=2.417, 95% CI=1.225 to 4.767); peak LDH level greater than 1600U/ml (RO=1.154, 95% CI=1.080 to 1.233). Patients with one independent risk factor had an estimated probability of 10.5% for developing inhospital cardiogenic shock; patients with two independent risk factors, 48.5%, patients with three risk factors, 65.0% patients with four risk factors, 65.7% patients with five risk factors, 67.2%. Conclusion: Of post-infarction cardiogenic shock during admission, 53% developed more than 24hours after admission. The more independent risk factors on admission for inhospital cardiogenic shock patients with acute myocardial infarction had, the more likely in-hospital cardiogenic shock developed.

Comparison of clinical outcomes of arthroscopic biceps long head tenodesis with or without tenotomy

Sang-Hun Ko,정광환,Hang Ki Kang 대한정형외과 스포츠의학회 2015 Arthroscopy and Orthopedic Sports Medicine Vol.2 No.1

Background: The present study aims to evaluate the clinical outcomes of tenodesis followed by tenotomy and tenodesis without tenotomy for biceps long head tendon lesions during arthroscopic small- to medium-sized full-thickness rotator cuff repair. Methods: This study was conducted on 33 patients who were available for at least 1-year regular follow-up after tenodesis of the long head of the biceps during arthroscopic small- to medium-sized full thickness rotator cuff repair between November 2009 and November 2010. Group I consisted of 20 patients who underwent tenodesis with tenotomy and group II consisted of 13 patients who underwent tenodesis without tenotomy. The outcomes were evaluated by visual analogue scale (VAS), UCLA scores, Speed’s test, and direct tenderness on the bicipital groove. Results: At the last follow-up, the VAS decreased from a preoperative mean of 7.5 to a postoperative mean of 3.0 in group I and from a preoperative mean of 8.0 to a postoperative mean of 3.2 in group II (P < 0.05). The UCLA score increased from a preoperative mean of 15.7 to a postoperative mean of 32.3 in group I and from a preoperative mean of 13.8 to a postoperative mean of 29.4 in group II (P < 0.05). The number of positive Speed’s test decreased from 13 preoperatively to 5 postoperatively in group I and from 9 preoperatively to 2 postoperatively in group II (P < 0.05). The number of patients with direct tenderness on the bicipital groove decreased from 17 preoperatively to 3 postoperatively in group I and from 12 preoperatively to 4 postoperatively in group II (P < 0.05). Conclusion: The use of tenotomy in combination with tenodesis for biceps long head tendon lesions had no significant impact on the clinical outcomes of arthroscopic rotator cuff repair.

Characterization of Newcastle Disease Virus at Slaughterhouses in Korea

Kang Seuk Choi,Soo Jeong Kye,Ji Ye Kim,Eun Kyoung Lee,Woo Jin Jeon,Jin Hwa Lee,Jun Hun Kwon,Choi Kyu Park,Haan Woo Sung 대한수의학회 2012 대한수의학회 학술대회발표집 Vol.2012 No.-

Characterization and Photocatalytic effect of ZnO nanoparticles synthesized by spray-pyrolysis method

Sang Duck Lee,Sang-Hun Nam,Myoung-Hwa Kim,Kang Suk Lee,Young Dok Kim,Jin-Hyo Boo 한국진공학회 2010 한국진공학회 학술발표회초록집 Vol.38 No.-

Problems with Agricultural Research and Development in Korea and Improvement Strategies Based on Foreign Examples with a Focus on the Ministry of Agriculture and the Rural Development Administration

Kang, Chung Han,Moon, Jung Hun,Kim, Nam Jung,Yun, Young Duk,Lee, Sung Chul Korean Society of Food and Agricultural Informatio 2011 Agribusiness and Information Management Vol.3 No.1

The dissemination process of agricultural research and development (R&D) results has somewhat different characteristics from that of typical R&D results. However, these characteristics are not adequately considered on the basis of an examination of the current performance system, the resulting management plans, and strategies for the application and dissemination of the results of agricultural R&D in Korea. The performance evaluation indicator exposed the problem of the inadequate consideration of the characteristics of each of these areas, particularly the lack of unified R&D-related institutions and the inadequacy of the system to monitor outcomes. To address these shortcomings in the agricultural R&D programs in Korea, the policies pertaining to agricultural R&D performance, results management, and dissemination in the U.S. and Japan were examined. Based on these investigations, we proposed strategies to improve the agricultural R&D policies in Korea.

Differential Potential of Stem Cells Following Their Origin

Sung Woo Sim(심성우),Young Lae Moon(문영래),Jung Hun Kang(강정훈) 대한견주관절의학회 2012 대한견주관절학회지 Vol.15 No.2

목적: 세가지 기원의 줄기 세포 분화능과 면역표현형을 평가하고자 하였다. 대상 및 방법: 견봉하 점액낭과 골수, 탯줄 혈액 세 개의 군에서 세포를 채취하였다. 견봉하 점액낭과 골수는 견관절 수술 환자군에게 임상적 동의 하에 수술중 채취하였다. 각각의 채취된 세포 및 탯줄 혈액에 대하여 계대 배양을 시행하여 신경 분화군, 지방 분화군, 골 분화군을 평가하였으며 세포 표면 항체를 밝히기 위해 유동세포분석법을 이용하였다. 결과: 견봉하 점액낭 유래 세포에서는 신경분화와 지방 분화는 8예 모두 (100%)에서, 골분화는 8례 중 5예 (62.5%)에서 성공할 수 있었으며 골수 유래 세포의 경우 신경 및 지방 분화 유도한 6례 및 5예 모두 (100%) 분화에 성공하였으나 골분화 유도는 5예 중 4예 (80%)에서 얻을 수 있었다. 반면 탯줄 유래 세포 분화 연구의 경우 신경 분화 유도 67례 중 65예 (97%)에서 지방 분화연구 54예 중 29예 (53.7%)에서 골 분화 연구 57예 중 39예 (68.4%)에서 성공할 수 있었다. 결론: 탯줄 유래 줄기세포의 분화능과 비교하였을 때 견봉하 점액낭 및 골수 유래 줄기세포의 분화능이 우수함을 알 수 있으며 이는 향후 세포 치료에 있어서 안정성 있는 치료 제공자가 될 수 있을 것으로 보이며 향후 생체 실험 연구의 참고 자료로서도 가치가 있을 것으로 보인다. Purpose: To evaluate the differentiation potential of stem cells and their immunophenotype from 3 different sources. Methods: Our study involved three stem cell sources-subacromial bursal tissue, bone marrow, and umbilical cord blood. We obtained the subacromial bursal tissue and bone marrow from the patients undergoing shoulder surgery. After collecting the sample, we applied specific induction media for neurogenic, adipogenic and osteogenic differentiation. Also, flow-cytometry analysis was done to reveal the cell surface antigens. Results: We obtained 100% (8 cases) neural and adipogenic differentiation, but 62.5% (5 of 8 cases) osseous differentiation among the subacromial bursal tissue group. Bone marrow derived cells showed 100% neural (6 cases) and adipogenic (5 cases) differentiation, but 80% (4 of 5 cases) osseous differentiation. Umbilical cord blood derived cells revealed 97% (65 of 67 cases) neural, 53.7% (29 of 54 cases) adipogenic and 68.4% (39 of 57 cases) osseous differentiation. Immunophenotype analysis revealed that surface markers of bone marrow, subacromial bursal cell and umbilical cord blood derived mesenchymal stem cells are different from each other. Conclusions: Mesenchymal stem cells are potential agents in regenerative medicine and are characterized by expression of surface markers and by their differentiation potential. Our study with stem cells from subacromial bursal tissue, bone marrow and umbilical cord discovered that each stem cell has unique differentiation potential and function based on its origin. Various stem cells show multi-lineage differentiations in vitro which can be correlated to in vivo conditions.

Basic : RON is associated with human hepatocellular carcinomaprogression via inhibition of apoptosis and cell cycle arrest through the modulation of ERK1/2 and Akt pathways (초)

( Sung Bum Cho ),( Young A Song ),( Yeon Joo Kim ),( Sang Hun Kim ),( Kang Jin Park ),( Seon Young Park ),( Wan Sik Lee ),( Chang Hwan Park ),( Hyun Soo Kim ),( Jong Sun Rew ),( Young Eun Joo ),( Sung 대한간학회 2011 Clinical and Molecular Hepatology(대한간학회지) Vol.17 No.3(S)

Optimal Gas Detection System in Cargo Compressor Room of Gas Fueled LNG Carrier

Sang-Won Lee,Yude Shao,Seung-Hun Lee,Jin-Uk Lee,Eun-Seok Jeong,Ho-Keun Kang 해양환경안전학회 2019 해양환경안전학회지 Vol.25 No.5

본 연구는 가스추진 174K급 LNG 운반선의 가스 압축기실에서 발생하는 가스누출 모사를 통해 가스탐지기의 최적 위치를 분석 하였으며, 새로 개정된 IGC 코드에 명시된 안전규정을 만족하는 합리적인 방법도 함께 제안하였다. 가스압축기실에서의 LNG 가스누출 수치해석을 위해, 실제 ME-GI 엔진이 장착된 174K급 LNG 운반선의 압축기실 형상과 장비, 배관의 배치와 같은 치수로 3D 설계되었다. 가 스누설에 대한 시나리오는 305 bar의 높은 압력과 1 bar의 낮은 압력을 적용하여 진행하였다. 고압용 핀홀의 크기는 4.5, 5.0, 5.6 mm이고 저압용은 100, 140 mm이다. 해석 결과, 5.6 mm 핀홀(고압)과 100, 140 mm 핀홀(저압) 상태의 누출에 대한 환기평가에서 가연성 가스농도는 심 각한 위험이 없음을 확인하였다. 그러나 개정된 IGC 코드에 따라 설치된 압축기실의 가스 감지 센서의 실제 위치는 다른 지점으로 이동 해야 하고, 측정 지점이 현 규정에서 요구하는 것보다 더 추가되어야 함을 확인하였다. This study analyzes the optimal location of gas detectors through the gas dispersion in a cargo compressor room of a 174K LNG carrier equipped with high-pressure cargo handling equipment; in addition, we propose a reasonable method for determining the safety regulations specified in the new International Code of the Construction and Equipment of Ships Carrying Liquefied Gases in Bulk (IGC). To conduct an LNG gas dispersion simulation in the cargo compressor room-equipped with an ME-GI engine-of a 174 K LNG carrier, the geometry of the room as well as the equipment and piping, are designed using the same 3D size at a 1-to-1 scale. Scenarios for a gas leak were examined under high pressure of 305 bar and low pressure of 1 bar. The pinhole sizes for high pressure are 4.5, 5.0, and 5.6mm, and for low pressure are 100 and 140 mm. The results demonstrate that the cargo compressor room will not pose a serious risk with respect to the flammable gas concentration as verified by a ventilation assessment for a 5.6 mm pinhole for a high-pressure leak under gas rupture conditions, and a low-pressure leak of 100 and 140 mm with different pinhole sizes. However, it was confirmed that the actual location of the gas detection sensors in a cargo compressor room, according to the new IGC code, should be moved to other points, and an analysis of the virtual monitor points through a computational fluid dynamics (CFD) simulation.

Electrical Characteristics of Single-silicon TFT Structure with Symmetric Dual-gate for Kink Effect Suppression

Kang Ey-Goo,Lee Dae-Yeon,Lee Chang-Hun,Kim Chang-Hun,Sung Man-Young The Korean Institute of Electrical and Electronic 2006 Transactions on Electrical and Electronic Material Vol.7 No.2

In this paper, a Symmetric Dual-gate Single-Si TFT, which includes three split floating n+ zones, is simulated. This structure drastically reduces the kink-effect and improves the on-current. This is due to the separated floating n+ zones, the transistor channel region is split into four zones with different lengths defined by a floating n+ region. This structure allows effective reduction in the kink-effect, depending on thy length of the two sub-channels. The on-current of the proposed dual-gate structure is 0.9 mA, while that of the conventional dual-gate structure is 0.5 mA, at both 12 V drain and 7 V gate voltages. This result shows an 80% enhancement in on-current. In addition, the reduction of electric field in the channel region compared to a conventional single-gate TFT and the reduction of the output conductance in the saturation region, is observed. In addition, the reduction in hole concentration, in the channel region, in order for effectively reducing the kink-effect, is also confirmed.

Improvement in the adhesion of bamboo fiber reinforced polylactide composites

Kang, Jun Tae,Park, Sang Ho,Kim, Seong Hun SAGE Publications 2014 Journal of composite materials Vol.48 No.21

<P>Polylactide composites containing bamboo fiber treated with various coupling agents were prepared using melt compounding. 3aminopropyltriethoxysilane, vinyltrimethoxysilane, maleic anhydride, and acrylic acid were used as the coupling agents to improve the mechanical properties of polylactide and bamboo fiber composites. In addition, to investigate the effect of fiber diameter on mechanical properties, either split bamboo fiber or fibrillar bamboo fiber was used as reinforcement. The composites containing split bamboo fiber treated with 3aminopropyltriethoxysilane and acrylic acid exhibited the highest tensile strength of all composites prepared. In addition, the composites containing fibrillar bamboo fiber showed a marked improvement in tensile strength. To investigate the biodegradability of the composites, an enzymatic degradation test was performed using Proteinase K, a commonly used enzyme for polylactide degradation. All the polylactide composites containing bamboo fiber, regardless of which coupling agent was applied, showed a similar trend in enzymatic degradation to that of neat polylactide.</P>