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위 MALT 림프종에서 다발성 림프절 전이로 오인된 동시성 림프절 결핵 1예
김성은,김규종,김도현,송준영,문대성,장리라,유찬희,문원,박무인,박선자,김영옥 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2
28세 남자가 내시경적 점막절제술을 통해 저등급 위MALT 림프종으로 진단되었다. 병기설정을 위해 18F-FDG PET 검사를 시행하였고 우측 쇄골상부, 우측상/하부 기관주위, AP window 부위에 강한 섭취가 관찰되어 전이성 림프절로 판단하였다. 그러나, 우측 쇄골상부 림프절에서 시행한 절제생검에서 만성육아종성염증소견이 관찰되었고 조직의 결핵 중합효소연쇄반응에서도 양성 반응을 보였다. 2개월간 항결핵제의 사용 후 시행한 추적 컴퓨터단층촬영 검사에서 림프절 크기의 감소를 보여 최종적으로 위 MALT 림프종에서 광범위 림프절 전이로 오인된 동시성 림프절 결핵으로 진단되었다. A 28-year-old man was diagnosed as gastric MALT lymphoma in diagnostic EMR (endoscopic mucosal resection). He subsequently underwent an 18F-FDG PET. 18F-FDG PET showed intense multifocal uptake in right supraclavicular, right upper and lower paratracheal, and AP window areas that was considered radiologically to represent widespread metastatic lymphadenopathy. Excisional biopsy of a supraclavicular lymph node, however, revealed chronic granulomatous lymphadenitis with a positive reaction of Tb-nested PCR. After antituberculosis treatment for 2 months, a follow-up CT scan showed complete resolution of the lesions. Intense 18F-FDG uptake could be due to an infectious process such as synchronous tuberculous lymphadenitis. Therefore, this could mimic a malignant condition such as lymphoma with extensive lymph node metastasis due to a false-positive finding, which may lead to a misdiagnosis.
Fe-17%Cr 페라이트계 나노사이즈-산화물 분산강화합금의 인장성질과 고온산화에 미치는 산화물종의 영향
김익수,강창룡,이종문,이병우,정상훈,이원희 대한금속재료학회 2003 대한금속·재료학회지 Vol.41 No.12
In order to develop mechanically alloyed nano-sized ferritic ODS alloys, we have investigated the effect of three kinds of oxide such as Y₂O₃, Al₂O₃ and TiO₂, on the high temperature tensile properties, high temperature oxidation behavior and corrosion resistance. Due to the most distribution of fine and spherical particles, ODS alloys containing Y₂O₃ raise yield strength and tensile strength at high temperatures considerably. The results of high temperature oxidation tests indicate that the ODS alloys containing Y₂O₃, Al₂O₃ and TiO₂ are resistant to oxidation between 823K and 1023K. The ODS alloy containing Y2O3 by attributed by to thermal safety of Y₂O₃ showed an ecellent characteristics in oxidation and corrosion.
Moon, Sang-Hyun,Kim, Si-Jin,Kim, Min-Cheol,Lee, Gyu-Ho,Choe, Hui-Seon,Han, Sang-Beom,Choi, Jong-Ho,Park, Kyung-Won Elsevier 2018 Journal of Alloys and Compounds Vol.741 No.-
<P><B>Abstract</B></P> <P>For advanced high-performance lithium-ion batteries (LIBs), a novel anode material with a high capacity needs to be developed. In particular, molybdenum disulfide (MoS<SUB>2</SUB>) with a layered structure consisting of S-Mo-S formed by van der Waals force exhibits a high theoretical capacity (1280 mAh g<SUP>−1</SUP>). In this study, MoS<SUB>2</SUB>-TiN electrodes were fabricated using a radio frequency (RF) magnetron sputtering deposition method by which MoS<SUB>2</SUB> and TiN sputtering targets could be individually controlled. As the RF power of the TiN target increased (20, 40, 60 W), the ratio of Ti in the electrodes increased and the ratio of Mo in the electrodes decreased. In particular, compared to pure MoS<SUB>2</SUB>, the MoS<SUB>2</SUB>-TiN with an optimum amount of TiN exhibited a high discharge capacity for 300 cycles and an improved high-rate cycling performance, i.e. an initial discharge capacity of 789.2 mAh g<SUP>−1</SUP> with the maintained capacity of ∼700 mAh g<SUP>−1</SUP> for 300 cycles. This demonstrates that TiN in the MoS<SUB>2</SUB>-TiN could reduce the volumetric variation caused by the conversion reaction of MoS<SUB>2</SUB> and assist in the improvement of the electrodes.</P> <P><B>Highlights</B></P> <P> <UL> <LI> MoS<SUB>2</SUB>-TiN nanostructured electrodes were fabricated using a co-sputtering deposition method. </LI> <LI> The electrode consists of MoS<SUB>2</SUB> as an active material and TiN as a matrix for lithium-ion batteries. </LI> <LI> MoS<SUB>2</SUB>-TiN nanostructured electrodes exhibited superior battery performance. </LI> <LI> The improved performance might be due to the suppressed volumetric change during the cycling. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Endoscopic Submucosal Dissection for Rectal Neuroendocrine (Carcinoid) Tumors
Moon, Sang Hui,Hwang, Jeong Hwan,Sohn, Dae Kyung,Park, Ji Won,Hong, Chang Won,Han, Kyung Su,Chang, Hee Jin,Oh, Jae Hwan Mary Ann Liebert 2011 Journal of laparoendoscopic & advanced surgical te Vol.21 No.8
<P>Rectal neuroendocrine (carcinoid) tumors smaller than 1???cm without lymph node metastasis and confined within the submucosal layer (stage T1aN0) can be treated using endoscopic resection. The present study was aimed to assess the safety and efficacy of endoscopic submucosal dissection (ESD) for T1aN0 carcinoid tumors.</P>
Synthesis and Antitumor activity of 4-Phenyl-1-1Arylsulfonyl Imidazolidinones
Jung, Sang-Hun,Lee, Hui-Soon,Song, Jae-Shin,Kim, Hwan-Mook,Han, Sang-Bae,Lee, Chang-Woo,Lee, Moon-Sun,Choi, Dong-Rack,Lee, Jung-Ah,Chung, Yong-Ho,Yoon, Sung-June,Moon, Eun-Yi,Hwang, Hyun-Sook,Seong, S 忠南大學校 癌共同硏究所 1998 癌共同硏究所 硏究誌 Vol.2 No.1
Novel l-(14>enzoylindoline-5-sulfonyl)-4-phenyl-4,5-dihydroimidazolones 3 synthesized show highly potent and broad cytotoxicities. Among them compound 3b (DW2143) exhibits much more potent cytotoxicities than doxorubicin and highly effective antitumor activities against murine (3LL, Colon 26) and human xenograft (NCI-H23, SW620) tumor models.
Sung-Gyu Lee,Shin Hwang,Tae Yong Ha,Gi Won Song,Dong-Hwan Jung,Gil-Chun Park,Chul-Soo Ahn,Deok-Bog Moon,Ki Hun Kim,Young-In Yoon,Yo Han Park,Hui-Dong Cho,Yong-Kyu Chung,Sang-Hyun Kang,Jin-Uk Choi,Sung 대한이식학회 2019 Korean Journal of Transplantation Vol.33 No.4
Background: Autologous portal vein Y-graft (PYG) interposition has been the standard procedure for reconstruction of double portal vein (PV) orifices of right liver grafts during living donor liver transplantations. However, it has the disadvantage of being vulnerable to anastomotic stenosis. A refined technique of conjoined unification venoplasty (CUV) was developed to secure PV reconstruction. Methods: We reviewed the surgical outcomes in PV reconstructions using CUVs in 21 cases which were followed up for >3 years. Results: The mean age of recipients was 51.7±4.9 years. The model for end-stage liver disease score was 15.3±6.4. The graft-recipient weight ratio was 1.12±0.21. Recipient PYGs were harvested in all cases. All living donors were blood relatives or relatives through marriage with type III PV anomalies. The number of right liver graft PV orifices was two in 19 cases and three in two cases. For the central intervening vein patch, a PV segment was used in six cases, and an autologous greater saphenous vein patch was used in the remaining 15 cases. The 21 patient cohort displayed a 100% 4-year patient survival rate. None of them underwent any PV interventions including interventional stenting. Serial follow-up computed tomography scans revealed that the reconstructed PV showed early reshaping with a stable streamlined configuration for over 3 years. Conclusions: PV reconstruction using the CUV technique appears to be significantly more effective in preventing PV complications. We believe that CUV is a useful technique to reconstruct right liver grafts with multiple PV orifices.
Sang-Hyun Kang,Shin Hwang,Chul-Soo Ahn,Ki-Hun Kim,Deok-Bog Moon,Tae-Yong Ha,Gi-Won Song,Dong-Hwan Jung,Gil-Chun Park,Jung-Man Namgoong,Young-In Yoon,Hui-Dong Cho,Jae-Hyun Kwon,Yong-Kyu Chung,Jin Uk Ch 대한이식학회 2020 Korean Journal of Transplantation Vol.34 No.1
Background: To understand the changing demands and recent trends in the indications for living donor liver transplantation (LDLT), the present study aimed to analyze the indications for LDLT performed in a high-volume transplantation center over 10 years. Methods: The liver transplantation database at our institution was searched to identify patients who underwent LDLT during a 10-year period from January 2008 to December 2017. The study subjects (n=3,145) were divided into two groups: adult patients (n=3,019, 92.7%) and pediatric patients (n=126, 3.9%). Results: In the adult recipients, the primary diagnoses were hepatitis B virus (HBV)- associated liver cirrhosis (n=1,898, 62.9%), alcoholic liver disease (n=482, 16.0%), hepatitis C virus-associated cirrhosis (n=203, 6.7%), acute liver failure (n=127, n=4.2%), and other diseases (n=157, 5.2%). The mean Model for End-Stage Liver Disease score was 15.6±8.8 (range, 6–40). The proportion of patients with HBV-associated liver disease gradually decreased, but the proportion of those with alcoholic liver disease increased. Hepatocellular carcinoma (HCC) was diagnosed in 1,467 patients (48.6%). The mean proportion of patients with HCC was 63.1% among those with HBVassociated liver disease. In pediatric recipients, the primary diagnoses were biliary atresia (n=51, 40.5%), liver failure of various causes (n=37, 29.4%), metabolic disease (n=22, 17.5%), hepatoblastoma (n=12, 9.5%), and infectious diseases (n=4, 3.2%). Conclusions: Our results showed that there were some significant changes in the indications of LDLT. We believe that our results may reflect the real changes in the indications of LDLT and they will be useful for predicting further changes in the future.