의예과 학생들의 성격유형검사(MBTI)의 특성

오윤경,장진영,박상학,류소연 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.1

Pmpose: To investigate the characteristics of Myers-Briggs Type Indicator (MBTI) in premedical students of one medical college and to compare the personality profiles of them with those of other studies which involved the K-orean university students and other country population. Mateiials and Methods: The MBTI was used to measure the personality profiles of premedical students at the Center for Teaching & Leaming of Chosun University. One hundred and twenty five premedical students participated in this study and the MBTI profiles of them were compared to those of K-orean university students (1,441 persons), i.e. their potential patients and those of the United Kingdom (UK.) Population (1,634 persons) and a sample of UK- doctors (313 persons) of one medical college involved in other studies. Results: The premedical students had a preference for Introversion (62%) rather than Extraversion (38%), Sensing (70%) rather than Intuition (30%), Thinking (66%) rather than Feeling (34%), and Judging (57%) rather than Perceiving (43%). There were more Thinking (66% vs 57%, p=0.071) in the premedical students than in K-orean university students with borderline significance. There were significantly more Thinking (66% vs 46%, P=0.000) and more Introversion (62% vs 48%, p=0.002) than in UK- adult population. Also there were significantly more Sensing (62% vs 48%, p=0.002), significantly less Judging (57% vs 68%, P=0.034), and more Introversion (62% vs 53%, 0=0.094) with borderline significance than in UK doctors. But no difference was shown in Thinking between the premedical students and UK- doctors, Conclusion: The personality profiles of the premedical students in this study differed in Thinking with borderline significance from K-orean university students and significantly differed from the UK adult population in Thinking and Introversion showing the cultural difference. No difference of Thinking between the premedical students and UK doctors despite of cultural difference suggests the correlation between the Thinking and medical professional choice.

11β-수산화효소 결핍에 의한 선천성 부신증식증 1예

류옥현,류혜진,박수연,권순범,박상수,김희영,이계원,서지아,오정헌,김신곤,김난희,최경묵,백세현,최동섭 대한내분비학회 2004 Endocrinology and metabolism Vol.19 No.1

저자들은 국내에서 처음으로 음핵 비대와 지속적인 질출혈을 주소로 내원한 19세 여성에서 고혈압이 동반되지 않으면서 11 -수산화효소 결핍으로 인한 선천성부신증식증을 경험하였기에 문헌 고찰과 함께 이를 보고하는 바이다. Congenital adrenal hyperplasia refers to a group of autosomal recessive disorders that is defective in the synthesis of cortisol. The enzymes most often affected are 21-hydroxylase and 11 - hydroxylase. The low levels of cortisol stimulate the pituitary gland to release ACTH. Chronic elevation of the ACTH level causes bilateral adrenal hyperplasia and a secondary increase in androgen formation. We examined a 19 year-old woman presented with clitoral hypertrophy and vaginal spotting. The subjects basal level of serum cortisol was low, but the serum levels of ACTH, 17a-hydroxyprogesterone, deoxy-corticosterone were elevated. The urinary excretions of 17-ketosteroids and 17-hydroxycorticosteroids were also increased. The karyotyping study and transrectal ultrasonography showed normal findings. The patient underwent clitoris reduction surgery and received hydrocortisone. To the best of our knowledge, this is the first case of 11 -hydroxylase deficiency in Korea (J Kor Soc Endocrinol 19:58∼63, 2004).

가토 대퇴정맥에서 헤파린 국소 적용과 혈관냉동이 미세혈관문합부 혈전 형성에 미치는 영향

김지영,오희균,유선열,김선헌 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.2

The effect of topical heparin application and vascular freezing on thrombosis was evaluated in the femoral vein of rabbits. The femoral veins were crushed, incised transverersely and treated by 4 different ways; 1) group 1, heparin treated only, 2) group 2, frozen only, 3) group 3, heparin treated and frozen,4) group 4, treated with saline as control. The patency was evaluated by empty-and-refill test and thrombus formation was judged by stereoscopic and SEM observation. The results obtained were as follows : 1.Thirty minutes after suture, the patency was more improved in the three groups than the control, but there was no significant difference among groups. 2.Three days after suture, the patency was more improved in the three groups than the control, and was prominent in group 1 and group 3 (P<0.05). 3.Significantly reduced thrombus could be seen in most case of group 3. These results suggest that topical application of heparin and vascular freezing is effective in

SOCS1 counteracts ROS-mediated survival signals and promotes apoptosis by modulating cell cycle to increase radiosensitivity of colorectal cancer cells

( Ji-yoon Ryu ),( Jiyoung Oh ),( Su-min Kim ),( Won-gi Kim ),( Hana Jeong ),( Shin-ae Ahn ),( Seol-hee Kim ),( Ji-young Jang ),( Byong Chul Yoo ),( Chul Woo Kim ),( Choong-eun Lee ) 생화학분자생물학회 2022 BMB Reports Vol.55 No.4

As negative regulators of cytokine signaling pathways, suppressors of cytokine signaling (SOCS) proteins have been reported to possess both pro-tumor and anti-tumor functions. Our recent studies have demonstrated suppressive effects of SOCS1 on epithelial to mesenchymal signaling in colorectal cancer cells in response to fractionated ionizing radiation or oxidative stress. The objective of the present study was to determine the radio-sensitizing action of SOCS1 as an anti-tumor mechanism in colorectal cancer cell model. In HCT116 cells exposed to ionizing radiation, SOCS1 over-expression shifted cell cycle arrest from G2/M to G1 and promoted radiation-induced apoptosis in a p53-dependent manner with down-regulation of cyclin B and up-regulation of p21. On the other hand, SOCS1 knock-down resulted in a reduced apoptosis with a decrease in G1 arrest. The regulatory action of SOCS1 on the radiation response was mediated by inhibition of radiation-induced Jak3/STAT3 and Erk activities, thereby blocking G1 to S transition. Radiation-induced early ROS signal was responsible for the activation of Jak3/Erk/STAT3 that led to cell survival response. Our data collectively indicate that SOCS1 can promote radiosensitivity of colorectal cancer cells by counteracting ROS-mediated survival signal, thereby blocking cell cycle progression from G1 to S. The resulting increase in G1 arrest with p53 activation then contributes to the promotion of apoptotic response upon radiation. Thus, induction of SOCS1 expression may increase therapeutic efficacy of radiation in tumors with low SOCS1 levels. [BMB Reports 2022; 55(4): 198-203]

Electrochemical Performances of the Sn-Cu Alloy Negative Electrode Materials through Simple Chemical Reduction Method

Oh, Ji Seon,Kim, Duri,Chae, Seung Ho,Oh, Seungjoo,Yoo, Seong Tae,Kim, Haebeen,Ryu, Ji Heon The Korean Electrochemical Society 2019 Journal of electrochemical science and technology Vol.10 No.3

Sn-Cu alloy powders were prepared via a simple chemical reduction method for the negative electrode materials in lithiumion batteries. The addition of Cu can suppress the growth of Sn particles during synthetic process. Furthermore, the Cu also acts as a matrix phase against the volume change during cycling. With increasing amount of the Cu, a stable $Cu_6Sn_5$ phase formed in the Sn-Cu alloy and its cycle performance greatly enhanced depending on the Cu content. To promote the generation of the $Cu_6Sn_5$ phase, the synthesis temperature is raised to $60-100^{\circ}C$ from the ambient temperature. The Sn-Cu alloy powders prepared at elevated temperatures showed remarkable cycle performances. The Sn-Cu alloy powder obtained at $60^{\circ}C$ exhibited a significantly high volumetric capacity of over 2,000 mAh/cc at the 50th cycle.

The Coating Effects of Al₂O₃ on a Li[Li_0.2Mn_0.54Co_0.13Ni_0.13]O₂ Surface Modified with (NH₄)₂SO₄

Oh, Ji-Woo,Oh, Rye-Gyeong,Hong, Jung-Eui,Yang, Won-Geun,Ryu, Kwang-Sun Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.5

A series of 20 wt % $(NH_4)_2SO_4$ and 3 wt % $Al_2O_3$ surface treatments were applied to $Li[Li_{0.2}Mn_{0.54}Co_{0.13}Ni_{0.13}]O_2$ substrates. The $Li[Li_{0.2}Mn_{0.54}Co_{0.13}Ni_{0.13}]O_2$ substrates were synthesized using a co-precipitation method. Sample (a) was left pristine and variations of the 20 wt % $(NH_4)_2SO_4$ and 3 wt % $Al_2O_3$ were applied to samples (b), (c) and (d). XRD was used to verify the space group of the samples as R$\bar{3}$m. Additional morphology and particle size data were obtained using SEM imagery. The $Al_2O_3$ coating layers of sample (b) and (d) were confirmed by TEM images and EDS mapping of the SEM images. 2032-type coin cells were fabricated in a glove box in order to investigate their electrochemical properties. The cells were charged and discharged at room temperature ($25^{\circ}C$) between 2.0V and 4.8V during the first cycle. The cells were then charged and discharged between 2.0V and 4.6V in subsequent cycles. Sample (d) exhibited lower irreversible capacity loss (ICL) in the first charge-discharge cycle as compared to sample (c). Sample (d) also had a higher discharge capacity of ~250 mAh/g during the first and second charge-discharge cycles when compared with sample (c). The rate capability of the $Al_2O_3$-coated sample (b) and (d) was lower when compared with sample (a) and (c). Sample (d), coated with $Al_2O_3$ after the surface treatment with $(NH_4)_2SO_4$, showed an improvement in cycle performance as well as an enhancement of discharge capacity. The thermal stability of sample (d) was higher than that of the sample (c) as the result of DSC.

Exploring the Effects of 630 nm Wavelength of Light-Emitting Diode Irradiation on the Proliferation and Migration Ability of Human Biceps Tendon Fibroblast Cells

Ji Hyeon Ryu,Jisu Park,Ji Won Kim,Yong-Il Shin,Sang Don Lee,Young Kwang Oh,Suk-Woong Kang 대한정형외과학회 2023 Clinics in Orthopedic Surgery Vol.15 No.1

Background: Light-emitting diode (LED)-based photobiomodulation is used as an inducer of cell regeneration. Although numerous in vitro and in vivo orthopedic studies have been conducted, the ideal LED wavelength range for tendon healing has not yet been determined. This study, thus, focused on the effects of LED of a 630 nm wavelength on the cell viability, proliferation, and migration of human biceps tendon fibroblast cells. Methods: Human tendon fibroblast cell culture was performed using the biceps tendon of patients who had undergone biceps tenodesis. Human biceps tendon fibroblasts from two patients (male, aged 42 and 69 years) were isolated and cultured. The cell type was confirmed by a morphological analysis and using tendon and fibroblast specific markers. They were then split into three groups, with each receiving a different irradiation treatment: no LED treatment (control), 630 nm LED, and 630 nm + 880 nm LED for 20 minutes each. After the LED treatment, cell viability, proliferation, and migration assays were performed, and the results were compared between the groups. Results: Twenty-four hours after LED treatment, cell viability and proliferation were significantly increased in the 630 nm LED and 630 nm + 880 nm LED treatment groups compared to that in the control group (p < 0.05). Under the same conditions, compared with the control group, the 630 nm LED alone treatment group showed a 3.06 ± 0.21 times higher cell migration rate (p < 0.05), and the 630 nm + 880 nm LED combination treatment group showed a 2.88 ± 0.20 times higher cell migration rate (p < 0.05) in threedimensional migration assay. Conclusions: In human tendon fibroblast cells, 20 minutes of LED treatment at 630 nm and 630 nm + 880 nm exhibited significant effects on cell proliferation and migration. Our findings suggest the potential of LED therapy as an adjuvant treatment for tendon healing, and hence, further research is warranted to standardize the various parameters to further develop and establish this as a reliable treatment regimen.

Electrochemical performance of all-solid lithium ion batteries with a polyaniline film cathode

Oh, Ji-Woo,Oh, Rye-Gyeong,Kang, Yongku,Ryu, Kwang-Sun Elsevier 2016 Journal of Energy Chemistry Vol.25 No.1

<P>We have prepared a high-density polyaniline (PANI) paste (50 mg/mL), with similar physical properties to those of paints or pigments. The synthesis of PANI is confirmed by Fourier transform infrared (FT-IR) spectroscopy. The morphologies of PANI, doped PANI, and doped PANI paste are confirmed by scanning electron microscopy (SEM). Particles of doped PANI paste are approximately 40-50 nm in diameter, with a uniform and cubic shape. The electrochemical performances of doped PANI paste using both liquid and solid polymer electrolytes have been measured by galvanostatic charge and discharge process. The cell fabricated with doped PANI paste and the solid polymer electrolyte exhibits a discharge capacity of similar to 87 mu Ah/cm(2) (64.0 mAh/g) at the second cycle and 67 mu Ah/cm(2) (50.1 mAh/g) at the 100th cycle. (C) 2015 Science Press and Dalian Institute of Chemical Physics. All rights reserved.</P>

Osteoporosis Is Associated with an Increased Risk of Colorectal Adenoma and High-Risk Adenoma: A Retrospective, Multicenter, Cross-Sectional, Case-Control Study

Nam Ji Hyung,Koh Myung,Kang Hyoun Woo,Ryu Kum Hei,Lee Dong Seok,Kim Su Hwan,Jang Dong Kee,Jeong Ji Bong,Kim Ji Won,Lee Kook Lae,Oh Dong Jun,Lim Yun Jeong,Koh Seong-Joon,Im Jong Pil,Kim Joo Sung 거트앤리버 소화기연관학회협의회 2022 Gut and Liver Vol.16 No.2

Background/Aims: The protective effects of vitamin D and calcium on colorectal neoplasms are known. Bone mineral density (BMD) may be a reliable biomarker that reflects the long-term anticancer effect of vitamin D and calcium. This study aimed to evaluate the association between BMD and colorectal adenomas including high-risk adenoma. Methods: A multicenter, cross-sectional, case-control study was conducted among participants with average risk of colorectal cancer who underwent BMD and screening colonoscopy between 2015 and 2019. The main outcome was the detection of colorectal neoplasms. The variable under consideration was low BMD (osteopenia/osteoporosis). The logistic regression model included baseline demographics, components of metabolic syndrome, fatty liver disease status, and aspirin and multivitamin use. Results: A total of 2,109 subjects were enrolled. The mean age was 52.1±10.8 years and 42.6% were male. The adenoma detection rate was 43%. Colorectal adenoma and high-risk adenoma were both more prevalent in subjects with low BMD than those with normal BMD (48.2% vs 38.8% and 12.1% vs 9.1%). In the univariate analysis, old age, male sex, smoking, metabolic components, fatty liver, and osteoporosis were significantly associated with the risk of adenoma and high-risk adenoma. In the multivariate analysis, osteoporosis was independently associated with risk of colorectal adenoma (odds ratio [OR], 1.65; 95% confidence interval [CI], 1.11 to 2.46; p=0.014) and high-risk adenoma (OR, 1.94; 95% CI, 1.14 to 3.29; p=0.014). Conclusions: Osteoporosis is an independent risk factor of colorectal adenoma and high-risk adenoma.

도로터널 내 수소차 수소누출 시나리오에 따른 가연영역에 대한 해석적 연구

유지오(Ji Oh Ryu),이후영(Hu Yeong Lee) 한국화재소방학회 2022 한국화재소방학회 학술대회 논문집 Vol.2022 No.춘계

화석연료의 고갈 및 환경문제의 대안으로 수소에너지가 부각되고 있으며, 수송분야에서도 수소차의 보급이 급격하게 증가할 것으로 예상된다. 그러나 수소는 가연농도 범위가 타 가스에 비해서 매우 넓고 폭발 가능성이 높기 때문에 수소차 안전에 대한 우려가 높은 실정이다. 특히, 반밀폐공간인 터널에서 수소누출에 따른 화재나 폭발이 발생하는 경우, 대형사고를 유발할 가능성이 높다. 이에 터널내에서 수소차 수소누출 시나리오에 따른 화재 안전성에 대한 검토가 필요하다. 본 연구에서는 터널에서 수소차 수소누출 시나리오를 H사의 N차량을 모델로 하여 작성하고 터널 풍속에 따른 수소확산 농도를 해석하여 가연하한농도(LFL) 이상의 영역(이하 가연영역)을 검토하여 화재발생 가능성을 검토하였다. 누출시나리오는 TPRD 장치의 작동 여부와 수소탱크의 균열을 고려하여 4개의 누출시나리오를 적용하였다. N차량에 탑재된 수소탱크의 용량 및 압력은 52.2리터×3개, 70MPa이며, TPRD의 직경은 1.8mm이다. TPRD를 통한 누출은 등엔트로피 누출로 가정하며, 최초 누출유량은 0.09 kg/s이며 누출은 약 180초 정도까지 지속되는 것으로 하였다. 수소 누출시 터널내 풍속 조건은 0, 1.0, 2.5m/s로 가정하였으며, 해석은 상용 CFD 프로그램을 사용하여 비정상상태로 수행하였다. 누출시 가연영역에 대한 검토결과, 동일한 누출시나리오에서는 풍속이 증가할수록 가연영역이 감소하며, 터널내 풍속이 0m/s인 경우, 가연영역의 체적은 누출 후 약 50초 정도에 500㎥정도에 이르나, 풍속이 2.5m/s인 경우에는 100㎥정도 크게 감소한다. 풍속이 2.5m/s인 경우에는 약 90초가 경과하면 가연영역의 체적이 0㎥에 도달하는 것으로 나타나고 있다. 또한, 1개의 수소탱크에 등가직경이 10mm인 균열이 발생하는 경우에는 누출은 10초 이내에 종료하며, 약 5초에서 정도에서 가연영역의 체적이 180㎥정도로 최대가 되며, 약 20초 이후에 가연영역의 체적이 0이 되는 것으로 나타나고 있다. 이상에서 도로터널의 경우, 수소 누출시 가연영역의 제척은 환기풍속에 크게 의존하는 것을 알 수 있다.