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      • KCI등재

        Characterization of a novel variant HMW‐glutenin gene from Elymus canadensis

        Qian‐Tao Jiang,Yu‐Ming Wei,Tao Liu,Ji‐Rui Wang,Zhi‐En Pu,Xiu‐Jin Lan,You‐Liang Zheng,Zhen‐Xiang Lu 한국유전학회 2010 Genes & Genomics Vol.32 No.4

        High molecular weight (HMW) glutenin subunits (GS) play a key role in the determination of end‐use quality of wheat and other cereal crops. In this study, we report the isolation and characterization of both promoter region and ORF of novel HMW‐GS allele 1St1.3 from a perennial Triticeae species,Elymus canadensis. The amino acid (AA) sequences of E. canadensis 1St1.3 were deduced as 434 aa. Its protein primary structure comprises a signal peptide with a conserved N‐terminal domain, a central repetitive domain and a C‐terminal domain. E. canadensis 1St 1.3 possesses several distinct characteristics which are different from those of wheat HMW‐GSs. The N‐terminal domains of E. canadensis 1St 1.3 resemble that of y‐type subunits, while their C‐terminal domains are more similar to x‐type subunits. The deletion of 85 bp fragment has been observed in promoter region of 1St 1.3, however which has not interrupted the expression of this gene. Our results indicate that 1St 1.3 is novel HMW‐GS variants which will be valuable for enhancing our understanding of structural differentiation and the evolutionary relationship among HMW‐GSs in Triticeae species.

      • KCI등재

        총성 없는 전쟁터 : 1950년대 중국에서의 북한문학 번역장

        등천 ( Deng¸ Qian ) 민족문학사학회·민족문학사연구소 2020 민족문학사연구 Vol.74 No.-

        본고에서는 1950년부터 1960년까지 중국에서 번역된 북한문학 작품들을 전반적으로 검토함으로써 1950년대 중국에서 북한문학 번역의 전모, 특징과 의의를 살펴보고 아울러 번역과 전쟁의 관계를 조명했다. 우선, 평화 시기와 달리 1950년대에 번역된 북한문학 작품들은 강한 시효성, 호소력과 대중성을 드러냈다. 장르별로 보면 르포르타주, 시가, 아동문학, 북한, 희곡 등을 폭넓게 번역함으로써 다양한 독자층을 최대한 포섭했다. 주제별로 보면 조선 인민의 수난과 투쟁, 미 제국주의의 침략과 폭행, 중· 조(中朝) 인민의 전우애를 형상화한 작품들을 번역함으로써 동맹국으로서의 상상된 공동체를 구축했다. 1950년대 북한문학 번역의 또 다른 특징은 동맹국 사이의 협업 번역으로 꼽힌다. 중국측에서는 일본어와 러시아어에 능통한 베테랑 번역자, 대학에 재직 중인 한인 교원, 한반도에서 귀국한 화교(華僑) 등 다양한 번역진을 조직하여 북한문학을 적극적으로 도입했다. 북한 측에서는 중국어에 능통한 번역자를 동원하여 자국문학을 계획적으로 중국에 수출했다. 6·25전쟁의 군사적 충돌과 이데올로기 간의 대치는 번역의 장에서 작용하여 문학 텍스트에 교묘하게 녹아들었다. 북한 작가 이북명의 소설 「악마」는 두 차례의 중국어 번역을 통해 각기 다른 양상으로 드러났다. 베이징 대학 한인 교원 마초군의 충실한 번역태도와 달리, 『인민문학』판 역본에는 편집자가 교묘한 첨삭을 통해 ‘사랑’과 ‘원한’의 이원적 감성 구조를 부각시키는 한편 전쟁으로 인해 조성된 부정적 감정을 대폭 은폐시켰다. 요컨대 1950년대 북한문학 번역장에서 선택과 배제, 강조와 은폐의 메커니즘이 작동하여 전쟁의 ‘실상’을 재구성하고 냉전의 심리적인 토대를 구축했다. 이런 측면에서 보면 1950년대 중국에서 활발하게 펼쳐진 북한문학 번역장은 이데올로기 투쟁의 ‘총성 없는 전쟁터’라 할 수 있다. In the early period after the foundation of the People’s Republic of China translation was institutionalized and entailed a political effect, which demonstrated in national translation program. It laid an institutional foundation for the translation of North Korean literature during the War to Resist U.S. Aggression and Aid Korea. The translation of North Korean literature in the 1950s was not only second only to Soviet literature in scale and quantity, but also reflected the publicity and propaganda function of wartime translation, thus presenting a special translation ecology. The paper, based on a survey of translation works of North Korean published in China from 1949 to 1960, through quantitative analysis and text reading, reveals three features of wartime translation. Firstly, the political orientation of the selection of source texts is prominent as well as popular. Secondly, import national translation by China and export national translation by DPRK, direct and indirect translation, foreign and local translators coexist simultaneously, which constitutes a pluralistic translation model. Thirdly, rewriting strategy is adopted to strengthen the Cold War mentality and weaken the negative emotions caused by the war, in order to demonstrate the justice of the war and prove the legitimacy of the People’s Republic of China. The authors contend that the translation of North Korean literature in the 1950’ subjectively demonstrated the wartime demands of the National Translation Program, and objectively participated in the construction of the literary genealogy of the War to Resist U.S. Aggression and Aid Korea.

      • How Does Power Distance Belief Impact Variety-Seeking Behavior? A Moderated Mediation Approach

        Qi An,Jinzhe Yan,Yeonggil Kim The International Academy of Global Business and T 2023 The International Academy of Global Business and T Vol.19 No.6

        Purpose - This research aims to enhance knowledge of variety-seeking behavior by establishing a novel antecedent based on consumer internal characteristics instead of external stimuli. The report also argues that the insights gleaned can illuminate a method to analyze consumer decision-making based on intrinsic motivation. This study evaluated a potential connection between power distance belief and variety-seeking behavior. This study evaluates variety-seeking behavior by brand, color, taste, and fashion preferences. Varietyseeking behavior is essential in understanding consumer choices. This paper aims to find the mechanism of the relation between power distance belief with variety-seeking behavior, along with the boundary condition of variety-seeking behavior. Design/Methodology/Approach - This study performed three experiments for measurement and hypothesis testing. This study employed analysis of variance, multiple regression, and process macro for moderated mediation testing with SPSS 28.0. Findings - This research confirms the prediction that higher power distance beliefs tend to elect variety through Study 1, and that risk-seeking mediates the moderation of boredom between power distance belief and variety-seeking behavior through Study 2. The authors conclude by discussing the implications for the application of the theory for managers. Research Implications - These contributions provide professionals with practical consequences for a variety of marketing tasks, such as market segmentation, product extension and innovation, and advertising guides.

      • The ERCC1 C118T Polymorphism Predicts Clinical Outcomes of Colorectal Cancer Patients Receiving Oxaliplatin-Based Chemotherapy: a Meta-analysis Based on 22 Studies

        Qian, Ying-Ying,Liu, Xin-You,Wu, Qian,Song, Xian,Chen, Xiao-Feng,Liu, Yi-Qian,Pei, Dong,Shen, Li-Zong,Shu, Yong-Qian Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.19

        Background: Although the predictive value of the excision repair cross-complementing group 1 (ERCC1) C118T polymorphism in clinical outcomes of patients with colorectal cancer (CRC) receiving oxaliplatin-based chemotherapy has been evaluated in numerous published studies, the conclusions are conflicting. Therefore, we performed the present meta-analysis to determine the precise role of the ERCC1 C118T polymorphism in this clinical situation and help optimize individual chemotherapy. Materials and Methods: A multiple search strategy was used to identify eligible studies. Pooled odds ratios (ORs) and their 95% confidence intervals (CIs) were used to estimate objective response and oxaliplatin-induced toxicity, with hazard ratios (HRs) with 95%CIs for progression-free survival (PFS) and overall survival (OS). Results: A total of 22 studies including 2,846 CRC patients were eligible in the analysis. Overall, no significant correlation was found between the ERCC1 C118T polymorphism and objective response to oxaliplatin-based chemotherapy, in all patients or in the Asian and Caucasian subgroups. However, the pooled analysis showed that the PFS and OS were significantly shorter in patients who carried T/T or T/C genotypes of ERCC1 C118T as compared to the C/C genotype. On stratified analysis by ethnicity, the ERCC1 118T allele was associated with a favorable prognosis in Caucasians (PFS, HR=0.58, 95%CI: 0.24-1.44; OS, HR=0.38, 95%CI: 0.22-0.64) but an unfavorable prognosis in Asians (PFS, HR=2.49, 95%CI: 1.87-3.33; OS, HR=2.63, 95%CI: 1.87-3.69) based on a dominant model. In addition, we failed to find a statistically significant impact of ERCC1 C118T polymorphism on oxaliplatin-induced toxicity. Conclusions: The ERCC1 C118T polymorphism may have prognostic value in patients with CRC undergoing oxaliplatin-based chemotherapy.

      • SCIESCOPUSKCI등재

        Highly Efficient Shoot Regeneration from Cotyledonary Nodes of Vegetable Soybean

        Qian-Qian Liu,Gang Chen,Jun-Yi Gai,Yue-Lin Zhu,Li-Fei Yang,Guo-Ping Wei,Cong Wang 한국원예학회 2010 원예과학기술지 Vol.28 No.2

        To establish a highly efficient system for shoot regeneration in vegetable soybean (Glycine max (L.) Merrill), explants were obtained from six genotypes and adventitious shoots were regenerated from cotyledonary nodes cultured on medium supplemented with different concentrations of N-phenyl-N′-1, 2, 3-thiadiazol-5-ylurea (thidiazuron TDZ) and 1-naphthylacetic acid (NAA). The most effective combination of plant growth regulators was selected first and then the effects of medium types, inoculation methods and genotypic differences on shoot regeneration were studied. The explants were inserted either vertically or horizontally into the medium and five basal media, including B5, ½ B5, MS, ½ MS, and MSB (MS salts and B5 organics), were tested. The shoot regeneration frequency of the six genotypes ranged from 53.5% to 88.9% and three of them reached 88.9%, 87.5% and 83.3%, respectively, on B5 medium supplemented with 1 ㎎?L<SUP>-1</SUP> TDZ, 0.05 ㎎?L<SUP>-1</SUP> NAA, and 5 ㎎?L<SUP>-1</SUP> AgNO₃. The shoot regeneration frequency of explants cultured on B5 medium was significantly higher than that of the other four basal media. The vertically inserted explants were found to yield a higher shoot regeneration frequency than that of horizontally inserted ones; the maximum difference of regenerating percentages between the two methods was 37.5%. In summary, TDZ was an efficient plant growth regulator for shoot induction. B5 medium and vertically inserted explants promoted shoot regeneration. We believe this highly efficient shoot regeneration system will provide foundation for the further transgenic studies in vegetable soybean.

      • KCI등재

        Stigma and Efficacy of Zhizhu Kuanzhong Capsules Versus Doxepin in the Treatment of Refractory Functional Dyspepsia: A Randomized Controlled Trial

        Qian-Qian Wang,Li Cheng,Bi-Yu Wu,Hong-Yi Qiu,Ping Xu,Bo Wang,Xiu-Juan Yan,Sheng-Liang Chen 대한소화기 기능성질환∙운동학회 2023 Journal of Neurogastroenterology and Motility (JNM Vol.29 No.3

        Background/AimsStigma related with antidepressants is prevalent in patients with functional dyspepsia. It affects medication compliance and efficacy. Herbal medicine acquired a deep-rooted cultural identity in relieving dyspeptic symptoms in Asians. The research was designed to compare the effectiveness of Zhizhu Kuanzhong capsules (ZZKZ) versus doxepin hydrochloride (doxepin) on alleviating stigma and medication nonadherence among patients with refractory FD (rFD). MethodsPatients with rFD from February 2021 to February 2022 were randomly allocated to receive either doxepin (n = 56) or ZZKZ (n = 57) combined with omeprazole for 4 weeks. Medication possession ratio (MPR), the disease- and medication-associated stigma were analyzed. The scales were utilized to assess dyspeptic symptoms (Leeds Dyspepsia Questionnaire) and psychological conditions (Generalized Anxiety Disorder Questionnaire and Patient Health Questionnaire). ResultsThe MPR values for ZZKZ were significantly higher than those for doxepin (P < 0.001). The stigma scores decreased in ZZKZ group while increased in doxepin group compared to baseline after treatment. The proportion of patients showing ZZKZ-associated stigma was significantly lower than doxepin-associated stigma (P < 0.001). The MPR values were negatively correlated with post-treatment stigma scores in both groups (P < 0.001). Dyspeptic symptoms and psychological condition were improved in both groups after treatment, with no significant difference on post-treatment Leeds Dyspepsia Questionnaire, Generalized Anxiety Disorder Questionnaire, or Patient Health Questionnaire scores between 2 groups. ConclusionZZKZ is superior to doxepin in alleviating stigma and medication non-adherence, with comparable efficacy in improving dyspeptic symptoms and psychological condition of patients with rFD.

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