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A Study on Development of the Optimal Neural Network in GMA Welding Process
Wu, Qian Qian,Lee, Ji Hye,Lee, Jong Pyo,Park, Min Ho,Kim, Young Su,Kim, Ill Soo Trans Tech Publications, Ltd. 2014 Advanced materials research Vol.936 No.-
<P>Gas Metal Arc (GMA) welding is considered as a multi-parameter process that it’s hard to find optimal parameters for good welding. To overcome the problem, an artificial neural network based on the backpropagation algorithm was built to realize the relationships between process parameters and welding quality as output parameter. In this study, Mahalanobis Distance (MD) was employed to evaluate the availability of a given welding parameters which was proved to performance well in multivariate statistics. Input parameters such as welding current and arc voltage were chosen due to their significant influence on the welding quality. To improve the precision of given parameters’ evaluation, neural networks with different configurations were verified. The analyses on the measured and predicted MD by the proposed neural network were conducted. The proposed neural network based on the error backpropogation algorithm was proved to have high reliability to evaluate process parameters, which further makes it available in on-line monitoring system.</P>
Protein Microarray Characterization of the <i>S</i> -Nitrosoproteome
Lee, Yun-Il,Giovinazzo, Daniel,Kang, Ho Chul,Lee, Yunjong,Jeong, Jun Seop,Doulias, Paschalis-Thomas,Xie, Zhi,Hu, Jianfei,Ghasemi, Mehdi,Ischiropoulos, Harry,Qian, Jiang,Zhu, Heng,Blackshaw, Seth,Dawso The American Society for Biochemistry and Molecula 2014 Molecular and Cellular Proteomics Vol.13 No.1
<P>Nitric oxide (NO) mediates a substantial part of its physiologic functions via <I>S</I>-nitrosylation, however the cellular substrates for NO-mediated <I>S</I>-nitrosylation are largely unknown. Here we describe the <I>S</I>-nitrosoproteome using a high-density protein microarray chip containing 16,368 unique human proteins. We identified 834 potentially <I>S</I>-nitrosylated human proteins. Using a unique and highly specific labeling and affinity capture of <I>S</I>-nitrosylated proteins, 138 cysteine residues on 131 peptides in 95 proteins were determined, defining critical sites of NO's actions. Of these cysteine residues 113 are novel sites of <I>S</I>-nitrosylation. A consensus sequence motif from these 834 proteins for <I>S</I>-nitrosylation was identified, suggesting that the residues flanking the <I>S</I>-nitrosylated cysteine are likely to be the critical determinant of whether the cysteine is <I>S</I>-nitrosylated. We identify eight ubiquitin E3 ligases, RNF10, RNF11, RNF41, RNF141, RNF181, RNF208, WWP2, and UBE3A, whose activities are modulated by <I>S</I>-nitrosylation, providing a unique regulatory mechanism of the ubiquitin proteasome system. These results define a new and extensive set of proteins that are susceptible to NO regulation via <I>S</I>-nitrosylation. Similar approaches could be used to identify other post-translational modification proteomes.</P>
M. W. Lee,H. J. Shin,S. H. Hong,J. T. Kim,임혜인,Y. Seo,이원희,P. Yu,M. Qian,J. K. Lee,K.B. Kim 대한금속·재료학회 2014 METALS AND MATERIALS International Vol.20 No.1
"Systematic investigation on thermal and mechanical properties of Cu60-xZr25Ti15Nix bulk metallic glasseswith x = 0, 1, 3, 5, 7, 9 and 11 at.% points out that monolithic Cu53Zr25Ti15Ni7 and Cu51Zr25Ti15Ni9 bulkmetallic glasses containing optimum Ni content of 7 and 9 at.% are effective to enhance both thermal sta-bility of amorphous structure up to 716 K and plastic strain of 2.4% at room temperature. This indicatesthat a selection of additional elements such as Ni by considering a mixing enthalpy to the constituent elementsis very important to control the thermal stability and plasticity. Moreover, it is believed that the addition ofminor Ni can be a trigger to form the chemical heterogeneity upon solidification. Such chemical heteroge-neity formed by the selection of the minor elements has a strong influence to cause the oscillation of theshear stress by wavy propagation of the shear bands thus leading the improvement of macroscopic plasticityof the bulk metallic glasses."
순무(Brassica rapa ssp.) 뿌리로부터 flavonoid의 분리 및 동정
정락훈 ( Rak Hun Jeong ),( Qian Wu ),조진경 ( Jin Gyeong Cho ),이대영 ( Dae Young Lee ),( Sabina Shrestha ),이민호 ( Min Ho Lee ),이경태 ( Kyung Tae Lee ),최명숙 ( Myung Sook Choi ),정태숙 ( Tae Sook Jeong ),안은미 ( Eun Mi 한국응용생명화학회(구 한국농화학회) 2013 Journal of Applied Biological Chemistry (J. Appl. Vol.56 No.1
순무뿌리(Brassica rapassp)를 실온에서 95% ethanol 수용액으로 추출하고 이 추출물을 ethyl acetate (EtOAc)분획, n-butyl alcohol 분획 및 H2O 분획으로 나누었다. EtOAc분획에 대하여 silica gel, ODS 및 Sephadex LH-20 column chromatography 를 반복실시 하여 5종의 flavonoid를 분리하였다. NMR, IR 및 MS data를 해석하여 각각 lic℃halcone A (1), 4,4`-dihydroxy- 3`-methoxychalcone (2), liquiritigenin (3), liquiritin (4), isoliquiritin (5)으로 구조동정하였다. 이들 화합물들은 순무뿌리에서는 처음으로 분리되었다. The roots of Brassica rapa ssp. were extracted with 95% aqueous ethanol and the concentrated extracts were partitioned using ethyl acetate (EtOAc), n-butyl alcohol and H2O, successively. From the EtOAc fraction, five flavonoids were isolated through repeated silica gel and ℃tadecyl silica gel (ODS) column chromatography (c.c.). Based on NMR, mass spectrometry (MS) and IR spectroscopic data, the chemical structures of the compounds were determined to be lic℃halcone A (1), 4,4`- dihydroxy-3`-methoxychalcone (2), liquirtigenin (3), liquiritin (4), and isoliquiritin (5). This is the first report of these compounds isolated from the root of this plant.