Acute exacerbation of interstitial lung disease; subgroup analysis for causes, risk factors for mortality rate, and steroid responsiveness

( Seung Hyun Yong ),( Ah Young Leem ),( Song Yee Kim ),( Kyung Soo Chung ),( Ji Ye Jung ),( Young Ae Kang ),( Young Sam Kim ),( Joon Chang ),( Moo Suk Park ),( Hye Jin Jang ) 대한결핵 및 호흡기학회 2019 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.127 No.-

Background: Interstitial Lung Disease (ILD) has known as a poor prognosis disease, particularly idiopathic pulmonary fibrosis (IPF). Corticosteroid is widely used for treatment of acute exacerbation (AE)-ILD. This study aims to clarify efficacy of corticosteroid use, and compare the mortality rate depending on the subgroups of ILD. Materials and Methods: We collected the data from the patients who have diagnosed ILD and visited emergency room (ER) with the respiratory symptoms from January 1, 2016 to December 31, 2018. We classified AE-ILD patients into 3 groups depending on methylprednisolone dose per kilogram. Also, we compared the mortality of IPF patients to that of non-IPF patients. Results: A total case of AE-ILD visited ER from 2016 to 2018 was 209 cases, including IPF cases (n=122) and non-IPF cases (n=87). We divided total patients (n=209) into three groups depending on steroid use, and these include group 1 of 0-0.49 mg/kg (n=78), group 2 of 0.5-0.99 mg/kg (n=58), and above 1.0 mg/kg (n=41), each. We found poor prognosis from the cases of IPF compared to non-IPF cases (p=0.029, OR 2.463). Furthermore, there was significant differences of mortality rate according to steroid dose (p=0.036, OR 1.712), CRP elevation (p=0.016, OR 1.004), and intubated case (p=0.000, OR 8.152). Also, we categorized IPF (n=122) to non-IPF cases (n=87) and analyzed the mortality rate. Most of the patients were death from ILD itself (n=23, 63.9%), Pneumonia(n=8, 22.2%), and Lung cancer (n=5, 13.9%). Bacterial infection (n=26) was dominant cause of AE, followed by fungal infection (n=15), and viral infection (n=10). Conclusions: This retrospective analysis of corticosteroid treatment shows more fatal outcome when we use high dose steroid in AE-ILD cases, and there was significant difference in mortality rate depending on the subgroup of ILD and medical background, such as intubation status, higher CRP level, and IPF cases.

S-528 : The Clinical Characteristics of Angioedema with Eosinophilia

( Hyo Jung Cho ),( Hye Soo Yoo ),( Mi Ae Kim ),( Yoo Seob Shin ),( Young Min Ye ),( Dong Ho Nahm ),( Joo Hee Kim ),( Jeong Hee Choi ),( Sun Young Park ),( Hae Sim Park ) 대한내과학회 2013 대한내과학회 추계학술대회 Vol.2013 No.1

Angioedema with eosinophilia (AE) is a very rare allergy disease, case reports of which have been published sporadically since 1984. Here, we retrospectively analyzed the clinical features of 10 AE patients in Korea. Nine of the 10 subjects were young females, ranging from 23 to 38 years old. Twenty percent of the subjects had episodic-type AE with high serum IgM and eosinophil counts, while 80% were non-episodic type with normal serum IgM levels but high eosinophil counts. All patients had used systemic corticosteroids to control AE. One patient with refractory EAE was treated with anti-IgE antibody. This is the first study to evaluate the clinical characteristics of AE in a Korean population.

한국에서의 간호중재분류체계(NIC)구조 타당성 검증

박성애,박정호,정면숙,박성희,염영희 서울대학교 간호대학 간호과학연구소 1999 간호학 논문집 Vol.13 No.2

The purpose of this study was to validate the NIC taxonomy in Korea. A sample of 10 nurse experts who were head nurses at a university affiliated hospital and had some knowledge and experience with research method and NIC rated, the NIC taxonomy twice using five criteria: clarity; homogeneity; inclusiveness; mutual exclusiveness; theory neutral. The NIC Taxonomy Evaluation questionnaire developed by the Iowa Intervention project team was used for data collection. The instrument was translation and back-translation. The results were as follows: 1. About fifty-eight percent of the respondents rated the domains as either quite characteristic or very characteristic on all criteria and about seventy -one percent of the respondents rated the classes as either quite characteristic or very characteristic on all criteria. 2. The criterion of theory neutral received the highest ratings and the criteria of clarity and inclusiveness received the lowest ratings on domains. 3. The criterion of theory neutral received the highest ratings and mutual exclusiveness received the lowest ratings on classes. 4. The Physiological: Complex domain received the highest ratings and the Family domain received the lowest ratings. These findings suggest that Nursing Interventions Classification System sensitive to Korean culture need to be developed.

서울·경기지역 병원직원의 혈액매개 감염노출에 대한 다기관 조사연구

박미라,김정은,박은숙,최정실,정선영,송영구,홍성관,김준명,허애정,양동규,조영주 대한병원감염관리학회 2003 의료관련감염관리 Vol.8 No.1

중환자실 병원감염에 대한 다기관 공동 조사연구

박은숙,박미라,진혜영,김정은,최정실,송영구,최영화,이위교,홍성관,허애정,양동규,김준명 대한병원감염관리학회 2003 의료관련감염관리 Vol.8 No.1

대학 구내 식당에 대한 이용자의 만족도

박영숙,이경애 순천향대학교 1993 논문집 Vol.16 No.3

This study was performed to improve the cafeterias on campus of S-University located in a small city in order to increase satisfaction of students with their campus lives. Subjects of 307 students were randomy selectedand asked to fill the questionaire sheets of 16 questions about the cafeterias on campus. The questions were prepared on the basis of the pre-surveyed data. Contents of the survey covered the preference to the cafeterias on campus and evaluation of several problems pointed by students as ones that should be improved. The evaluation was ranked by 5-points scale. We found that menu preference and diversity were most serious problems faced by college location, and the other near dormitary steadily because of good food taste and amounts in spite of its edge location. Taste , nutrition, food preference, menu diversity and amounts of foods of the cafeterias were evaluated below average. Price of foods, service, tray return method, waiting time, cleanness of dishes and hygiene were also scored below average. The environment of the cafeterias like location, open time, ventilation and light were also evaluated below average.

보육교사교육원생들의 유아다례교육에 대한 인식 및 요구도

박정현,주영애 誠信女子大學校 生活文化硏究所 2011 生活文化硏究 Vol.26 No.1

The purpose of this study is to reinforce children's tea ceremony education for trainees of child care training programs by investigating the demand for such education by the trainees and securing fundamental research data to be used by the training program providers. The sample subjects used for this study are trainees in Gyeongsangnam-do Province taking the child care training program by the Institute of Child Care Education. A total of 310 survey questionnaires were distributed, and when the filled-out questionnaires were collected, respondents were discarded because they had not answered the questions appropriately, and the remaining 287 samples were used for analysis. The collected data were statistically processed using SPSS 17.0, and Frequency Analysis, ANOVA, Correlation Analysis were conducted. The following is a summary of the results: 1. As for the trainees' perception of children's tea ceremony education, 42.5% answered they had heard of such education, while 57.5% said they had ‘never heard of it.’8.4% showed ‘very high’interest in it, and 38% ‘somewhat high.’Overall, 46.4% showed an interest in tea ceremony education. On the benefit of tea ceremony education, 35.9% answered ‘good behavior,’followed by ‘patience and consideration for others’(26.8%), and ‘nurturing pride in Korean traditional culture’(13.2%). 2. The demand for children's tea ceremony education was examined in three different aspects, namely, tea theory, tea practice, and tea manners. As for the general characteristics of the respondents, the demand for children's tea ceremony education was higher in those in their 20s than those in their 30s. Higher demand was also observed among ‘2-year college graduates’and ‘high-school graduates.’The demand levels varied significantly according to differences in the interest levels. 3. It turned out that the demand for children's tea ceremony education affected the approach to the education. In particular, the demand for tea ceremony education appeared to have the most significant influence on the approach to the education. 4. As for the demands made for tea practice and the improvement of educational operation, the element of 'preparing tea cookies and treating guests with them' showed a higher correlation with 'having a tea practice room'(.478) and 'participating in a competition event'(.441). 'Setting up tea table' also showed a higher correlation with 'having a tea practice room'(.481) Meanwhile, in the demands made for tea manners and the improvement of educational environment, 'salute manners' showed a higher correlation with the 'connection to traditional Korean culture'(.392) and 'a need for training of the teachers'(.366.) These results indicate that the demands by the trainees can help to conduct tea ceremony education more effectively, and that it would be necessary to provide a systematic and more specialized training for the teachers.

급성 췌장염의 합병이 추정되는 한국형 출혈열 1예

박영수,김창오,김영근,홍성관,장경희,허애정,염준섭,송영구,김준명 대한감염학회 2001 감염 Vol.33 No.5

The Korean hemorrhagic fever (KHF) is an acute febrile disease with characteristic of fever, bleeding tendency, and renal failure. There are many complications of Korean hemorrhagic fever such as infection, anemia, internal bleeding, hypopituitarism, respiratory, and neurologic complication. A few cases were reported on acute pancreatitis with hemorrhagic fever abroad, but there was no case about Korean hemorrhagic fever with acute pancreatitis in this country. We experienced a case of Korean hemorrhagic fever associated with suspected acute pancreatits. With review of articles, we report a case of 51 year-old woman with KHF, where acute pancreatitis developed during management, (Korean J Infect Dis 33:376∼379, 2001)

대전 충남지역 국민학교의 학교급식 실태에 관한 조사

박영숙,이경애,김연순 순천향대학교 기초과학연구소 1995 순천향자연과학연구 논문집 Vol.1 No.1

The foodservice management of school-lunch program was studied to certify the fulfillment of it's objectives. One hundred thirtheen primary schools in Taejon and Chungnam province were participated in our survey. The results of this study were as follows: 1. Average cost per meal for each student was 772 won, that was less in central kitchen system. Productivity in terms of meals per worker was also higher in centralized kitchen system. 2. The menu was mostly planned weekly and not cyclic. 3. The dietitian's work covered all 5 parts of material handling duties in conventional system which were described in the school-lunch program laws. However it was mainly concentrated on 2 parts of the food purchase order and of the inspection of delivered foods in co-management and central kitchen systems. 4. Our results indicated that nutrition education in school-lunch program especially in co-management and central kitchen systems was almost neglected. It was stressed that school-lunch program should be extended without omitting its objectives especially nutrition education, which is important for the young.

저분자량 항원에 대한 난황 항체의 유도

박영숙,이경애 순천향대학교 기초과학연구소 1995 순천향자연과학연구 논문집 Vol.1 No.1

The yolk antibody responses in laying hens to insulin derivatives as low molecular weight immunogens were investigated. Insulin derivatives were reduced and carboxymethylated(RCM) insulin, and RCM-A and RCM-B chain of insulin. The anti-RCM-A chain yolk antibodies appeared after the first immunization and showed no cross reactivities with native insulin. The anti-RCM-B chain yolk antibodies were elicited 5 weeks after the third booster injection and recognized native insulin. The anti-RCM insulin yolk antibodies were induced after the second booster injection and recognized native insulin.