열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

집합조직을 이용한 알루미늄판재의 성형성 향상에 관한 연구

이문규,제창웅,박노진 國立金烏工科大學校 産業技術開發硏究院 2002 産業技術開發硏究 Vol.18 No.-

In order to improve the formability of Al-sheet, control of the crystallographic texture is essential because of the anisotropic nature of plastic properties. The formation of texture is governed by the thermomechanical processes such as cold rolling and annealing. In order to obtain different textures, cold rolling with/without lubrication and recrystallization were applied. The through-thickness texture gradient is formed during the cold rolling without lubrication. The center layer mainly consisted of the β-fiber texture but surface layer was composed of (001}<100) shear texture. Recrystallization with rolling texture of β-fiber led to typically an increase of the {001<100>-Cube component at the expense of the β-fiber orientation. However, from the rolling of {001}<100). shear component the recrystallization texture was observed which is composed by relatively strong {0.469 .814 0.342}<0.848 0.524 0.082>-, {112}<7 11 2>- and weak {001}<110>- {011}<011>-components. Much higher r-values were estimated with {0.469 0.814 0.342}<0.848 0.524 0.082>- {112}<7 11 2>-components than {001}<100>-Cube recrystallization texture.

갑상선 소결절들의 초음파 소견에 관한 고찰

李紋圭,韓昌烈 인제대학교 1989 仁濟醫學 Vol.10 No.2

갑상선 질환의 진단에 있어서 고해상능의 초음파검사를 이용하면 종래의 동위원소 스캔보다 더 많은 갑상선 소결절들을 검출할 수 있으며, 잠재 암의 조기 검출 및 초음파 유도하에 세침흡입생검을 할 수 있는 장점이 있다. 이에 저자들은 갑상선의 양성 및 악성종양의 초음파검사 소견을 분석하였고 동시에 각 질환의 감별점을 알아보고자 하였다. Prospective analysis of the pathologically proven 12 patients was performed, focused mainly on the ultrasonographic findings of the thyroid nodules with the special attention to the diagnostic feasibility of benignancy or malignancy solely by ultrasonography. Findings suggesting benign nodules include solid hyperechoic nodules, cystic nodules of supposedly haying low malignancy, calcifications of centrally located, coarse, and curvilinear pattern, appearance of peritumoral halo sign, and mural nodules on the wall of cystic masses. I11-defined margin of nodules and incomplete pattern of peritumoral halo sign might be levered as the malignant sign of thyroid nodules. Authors suggest that high-resolution thyroid ultrasonography should be carried out in the patients of single cold nodule detected by radioisotope thyroid scan, to indentify multinodular goiter, to assess the response of a given nodule to the suppressive hormonal therapy and to be used as a guide to the fine-needle aspiration for the lesions showing areas of hemorrhage and necrosis.

상부 조기 위암 환자의 복강경하 상부 위절제술 3례 경험

조규석,김형철,박경규,이문수,송옥평,임철완,신웅진,주종우,유기원 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Background : The reported incidence of early gastric cancer located in the upper portion of the stomach has been increasing with the recent advances in its diagnosis and screening. Recently, we have successfully performed laparoscopic assisted proximal gastrectomy and gastric tube reconstruction without pyloroplasty on three patients with early gastric carcinoma localized to the upper third of the stomach. We describe our modification of this procedure in this report. Method : After creating an surgical pneumoperitoneum, the stomach was mobilized using laparoscopic coagulating shears. Upper half of the greater curvature and three-quarters of the lesser curvature were then dissected along with regoinal D2 lymphadenectomy. This was followed by a 5 cm, longitudinal mini-laparotomy in the upper abdomen, and the construction of the exteriorized stomach with a gastric tube measuring 20 cm long and 4 cm wide. Reconstruction with an esophagogastrostomy was performed using a circular stapler. Result : No post-operative morbidity or mortality was observed in this small series of patients. The average operative time was 250 minutes (range 220-300 minutes), and the average blood loss was 150 ml (range 90-180 ml). The mean number of lymph nodes harvested during these laparoscopic proximal gastrectomies was 24 nodes (range 22-25 lymph nodes). The average postoperative hospital stays was 7.5 days (range 7-8 days). Conclusion : Our technique of laparoscopic assisted proximal gastrectomy and gastric tube reconstruction without phloroplasty offers a minimally invasive technique with the potential of impoving the post-operative quality of life patients with an early-stage proximal gastric cancer.

多色發光形 AC 薄膜電場發光素子

羅炳旭,李相潤,孫相豪,朴汶圭 慶北大學校 自然科學大學 1986 自然科學論文集 Vol.4 No.-

Multi-colored AC thin film electroluminescence devices have been fabricated by electron beam evaporation. The green and red light emission were observed and the emission brightness B were measured as the function of applied voltage V, frequency f and concentration of the rare-earth materials. The brightest emission was observed for the ZnS:TbF_3 devices and the value was 700f-L.

구리 耐性菌(Pseudomonas stutzeri)의 菌體內 구리 蓄積機作

許鍾秀,曺周植,韓文圭,李洪宰,林永成 경상대학교 환경보전연구소 1994 環境保全硏究所報 Vol.2 No.1

In order to study the mechanism of the copper accumulation in the cell of copper-tolerant bacterium, Pseudomonas stutzeri, distribution of the copper in the cell were investigated. Approximately 61% of the accumulated copper was distributed on the cell wall and the other 39% portion was in cytoplasm. 78% of the copper in the cell wall fractions was present in the polyphosphate and polysaccharide fractions, but most of copper in the cytoplasm fractions was in protein and nucleic acid. Copper affected the protein synthesis in P. stutzeri. The intracellular protein content was decreased by copper addition, but the soluble protein precipitated by ammonium sulfate(30-75% saturation) was increased as compared to that from the cells grown without copper. Furthermore, in the cells grown with copper, high-molecular-weight soluble protein was increased, compared with the cells grown without copper, but low-molecular -weight soluble protein was decreased. These results indicate that copper inhibited the intracellular protein biosynthesis but enhanced the biosynthesis of the high-molecular-weight soluble protein precipitated by ammonium sulfate(30-75% saturation).

銅鑛山廢水로부터 分離한 구리 耐性菌(P.stutzeri)의 菌體內 구리 蓄積 特性

許鍾秀,曺周植,韓文圭,李洪宰,林永成 경상대학교 환경보전연구소 1994 環境保全硏究所報 Vol.2 No.1

Of the copper-tolerant 215 bacterial strains isolated from polluted river water, wastewater and activated sludges of wastewater treatment plants, or wastewater and soils of the copper mine aera in Gyeongnam province a strain, which showed considerably higher growth rate in the agar plate containing 2000ppm of copper than any other strains, was identified as a Pseudomonas stutzeri or its similar strain when analyzed by taxonomical charicteristics. Optimum pH and temperature for the growth of the P. stutzeri were 7.0 and 30℃ respectively. This strain was resistant to antibiotics, such as ampicillin and tetracycline, and heavy metals, such as lead and chromium. This strain utilized phenol benzen or toluene as a sole carbon source. The rate of copper accumulation in P. stutzeri cell was enhanced at low concentration of Cu in the growth media. The maximum copper absorption by this strain grown in 10ppm of Cu at 3 days after culture was 49%, but in 50ppm and 100ppm of Cu was 38% and 32%, respectively. The optimal temprature and pH for the effective intracellular accumulation of copper were 30℃ and initial pH 8.0 under shaking culture.

Decreased blood pressure associated with in-vehicle exposure to carbon monoxide in Korean volunteers

Lee, Geon-Woo,Bae, Mun-Joo,Yang, Ji-Yeon,Son, Jung-Woo,Cho, Jae-Lim,Lee, Sang-Gyu,Jang, Bo-Mi,Lee, Hyun-Woo,Lim, Jong-Soon,Shin, Dong-Chun,Lim, Young-Wook BioMed Central 2017 Environmental health and preventive medicine.['97. Vol.22 No.-

<P><B>Background</B></P><P>Carbon monoxide (CO) is one of the primary components of emissions from light-duty vehicles, and reportedly comprises 77% of all pollutants emitted in terms of concentration. Exposure to CO aggravates cardiovascular disease and causes other health disorders. The study was aimed to assess the negative effects by injecting different amounts of CO concentration directly to human volunteers boarding in the car.</P><P><B>Methods</B></P><P>Human volunteers were exposed to CO concentrations of 0, 33.2, and 72.4 ppm, respectively during the first test and 0, 30.3, and 48.8 ppm respectively during the second test while seated in the car. The volunteers were exposed to each concentration for approximately 45 min. After exposure, blood pressure measurement, blood collection (carboxyhemoglobin [COHb] analysis), medical interview, echocardiography test, and cognitive reaction test were performed.</P><P><B>Result</B></P><P>In patients who were exposed to a mean concentration of CO for 72.4 ± 1.4 ppm during the first exposure test and 48.8 ± 3.7 ppm during the second exposure test, the COHb level exceeded 2%. Moreover, the diastolic blood pressure was decreased while increasing in CO concentration after exposure. The medical interview findings showed that the degree of fatigue was increased and the degree of concentration was reduced when the exposed concentration of CO was increased.</P><P><B>Conclusion</B></P><P>Although the study had a limited sample size, we found that even a low concentration of CO flowing into a car could have a negative influence on human health, such as change of blood pressure and degree of fatigue.</P>

Study on Cat Robot Utilization for Treatment of Autistic Children

Lee, Jin-Gyu,Lee, Bo-Hee,Jang, Ju-Yeong,Kwon, Ja-Young,Mun, Keum-Hi,Jung, Jin-Soun World Scientific Publishing Company 2017 International Journal of Humanoid Robotics Vol.14 No.2

<P>This study deals with language therapy and play therapy using a cat robot for children with autistic spectrum disorders (ASDs) and verifies the effects of such therapy. Two versions of cat character robots, so-called Semyung robot (SERO) I and II, are suggested. First, SERO I is applied in the field test, which indicated some effective tendancy of ASD children. The robot design was improved accordingly, and the second field test was performed. Through the two field tests, we verified that this robot can be used effectively in the treatment of ASD children.</P>

Radioscintigraphic Findings in Budd-Chiari Syndrome Due to Obstruction of Inferior Vena Cava

Lee, Choong Ki,Lee, Myung Shik,Lee, Mun Gyu,Sung, Dong Wook 대한핵의학회 1986 핵의학 분자영상 Vol.20 No.1