물표면 방전을 이용한 클로로포름의 분해

유승민 ( Seung Min Ryu ),유승열 ( Seung Ryul Yoo ),박준석 ( Jun Seuk Park ),홍은정 ( Eun Jung Hong ),노태협 ( Tai Hyeop Lho ) 한국물환경학회 2013 한국물환경학회지 Vol.29 No.5

Chloroform is harmful volatile organics and representatives of Trihalomethane (THM). Well-known removal methods of Chloroform are photo oxidation or OH radical oxidation. Plasma on water surface at slightly vacuum condition (45 torr) can produce OH radical and it will help chloroform removal. 81.5% of chloroform is removed by vacuum and plasma in 10 min. Plasma can totally oxidize it till 2.8% and partially oxidize chloroform up to 18.5%. Water-surface plasma is good method to remove chloroform in short time.

산업단지 및 일반생활 지역의 공기 중 톨루엔에 대한 개인노출 및 생체시료의 상관성 분석

이병준(Byoungjun Lee),허 정(Jung Heo),정다영(Dayoung Jung),김순신(Sunshin Kim),류현수(Hyeon-Su Ryu),최민지(Min-Ji Choi),솨이지엔페이(Jian-Fei Shuai),임성국(Sung-Guk Im),양원호(Wonho Yang) 한국환경보건학회 2017 한국환경보건학회지 Vol.43 No.4

Objectives: The purpose of this study was to assess the correlation relationship between personal exposure and urinary hippuric acid in biological monitoring for airborne toluene in an industrial complex and in general environments. Methods: Personal exposure to toluene and its metabolite, hippuric acid, in urine were simultaneously measured in occupational environments area near an industrial complex and in general environments. The study subjects were divided into three types: 137 workers who use organic solvents in the workplace, 210 residents living near a dyeing industrial complex, and 379 residents living in general environments. The toluene exposures of workers and residents were measured by a passive sampler for four days. The urine of participants was sampled when the passive samplers of personal exposure were collected. Results: The toluene and hippuric acid concentrations of workers were the highest, followed by the concentrations of residents living near a dyeing industrial complex and residents living in general environments. The coefficient of correlation between the concentrations of toluene and hippuric acid among workers was 0.749 (p<0.01) in the workplace. On the contrary, correlations between the concentrations of toluene and hippuric acid among residents living near a dyeing industrial complex and residents living in general environments were all not significant. The relationship between the concentrations of hippuric acid and toluene in three types could be described by the exponential growth model. Conclusions: This study analyzed the relationships between toluene exposure and the concentrations of hippuric acid in urine in high, middle, and low exposure environments, and could be described by the exponential growth model.

다발성 골수종에서 저용량 thalidomide, cyclophosphamide, dexamethasone (TCD) 요법의 효과

류충헌,정재현,고정해,장제혁,박영진,최규남,박봉수,이상민,주영돈 인제대학교 2008 仁濟醫學 Vol.29 No.-

Background and Objectives : The immunomodulatory drug thalidomide can inhibit angiogenesis and induce apoptosis in experimental models. It can also induce marked and durable response in newly diagnosed myeloma patients. Thalidomide has been used at doses ranging from 200 to 800 mg with significant toxicity. No data are available on the impact of low-dose thalidomide, cyclophosphamide and dexamethasone as initial therapy for myeloma patients. Design and Methods : To address this issue, newly diagnosed myeloma patients were treated with 50 mg/day thalidomide continuously and cyclophosphamide 150 mg/m², days 1-4 and dexamethasone 20 mg/m², days 1-5 and day 15-19, every month. Between October 2005 and October 2006, 14 patients (median age 54.5 years) were treated with low-dose thalidomide, cyclophosphamide and dexamethasone. Results : After a minimum of two cycles of treatment, 5 patients (55.5%) showed a partial remission. After four cycles of treatment, 10 patients (83.3%) showed a partial remission (n=6) and complete remission (n=4). After a median follow-up of 15.4 months, 1 year overall survival rate was 82.0%. Thalidomide was well tolerated without serious toxic effects. Conclusions : The combination of low-dose thalidomide, cyclophosphamide and dexamethasone demonstrates favorable response rate and 1 year overall survival rate in newly diagnosed myeloma. Severe toxicities were not seen with this combination.

괴사성 장염 환아의 금식기간 결정을 위한 Iohexol의 유용성 : Iohexol의 위장과 투여 후 채취한 소변을 전산화단층촬영법을 이용

정유진,홍성완,류민현,정철주,문경래 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

Background: Necrotizing enterocolitis is the most common gastrointestinal emergency in the neonates and its course is often fulminating with progressive lethargy. The purpose of this study is to determine the period of NP0(non per os) treatment in the patients with neonatal necrotizing enterocolitis. Matenal and methods: For determining the normal range of CT(Computerized tomography) attenuation coefficients of urine from normal neonates, 60 normal neonates participated in this study. And urine specimens from 16 patients with stage IIB necrotizing enerocolitis were obtained 8-12 hours after the instillation of iohexol enterally. The attenuation coefficients of each urine specimen were determined with CT. Periodic examinations were performed at an interval of two days. As soon as the values of attenuation coefficients reached the normal range, we discontinued NPO treatment. Results: The mean period of NPO treatment of 16 patients with stage IIB necrotizing enterocolitis was 11.1 days. The NPO period of 6 patients were 8 days, two were 10 days, four were 12 days, one was 14 days and three were 16 days. Conclusion: By means of this study, we were able to determine the period of NPO treatment on a case by case basis. The authors think that CT examination of the obtained urine after the instillation of iohexol may be a good method to determine the period of NPO treatment.

OB-11 : Placental microRNAs as potential biomarkers for noninvasive detection of trisomy 21

( Min Hyoung Kim ),( Ji Hyae Lim ),( Da Eun Lee ),( Jung Yeol Han ),( Moon Young Kim ),( You Jung Han ),( So Yeon Park ),( Hyun Mee Ryu1 ) 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-

목적: The discovery of fetal nucleic acids in the plasma of pregnant women has led to the development of noninvasive prenatal testing (NIPT). The objective of this study was to discover a panel of placental miRNAs as potential novel biomarkers for NIPT of fetal T21 and to predict the biological functions of new biomarkers using bioinformatics tools. 방법: Using microarray-based genome-wide expression profiling, we compared the expression levels of miRNAs in whole blood samples from non-pregnant women, whole blood samples from pregnant women, and fetal placenta samples from pregnant women with euploid or T21 fetuses. We analyzed the differentially expressed miRNAs according to the presence or absence of disease and tissue type (p value <0.05 and two-fold expression change). Potential target genes of miRNAs were predicted using the miRBase program. To predict their functions, the functional annotation tools provided by the WebGestalt database were used. 결과: We identified 299 miRNAs which reasonably separate the whole blood from the placenta. Among the identified miRNAs, 150 miRNAs were up-regulated in the placenta, and 149 miRNAs were down-regulated. Most of the up-regulated miRNAs in the placenta were members of the mir-498, mir-379, and mir-127 clusters as placenta specific miRNA located on hsa19 and hsa14. Among the up-regulated miRNAs in the placenta, mir-1973 and mir-3196 were expressed at higher levels in the T21 placenta than in the euploid placenta. The two miRNAs potentially regulate 203 target genes that are involved in developmentof brain, central nervous system, and nervous system. Interestingly, the genes are significantly associated with T21-related disorder such as congenital abnormalities, mental disorders, and nervous system diseases. 결론: Our study indicates placenta-specific miRNAs that may be potential biomarkers for NIPT of fetal T21 and provides new insights into the molecular mechanisms of T21 via regulation of miRNAs.

패밀리 프로그램 개발을 위한 패밀리 팩 스펙 분석

정민수,류동항 慶南大學校 附設 工業技術硏究所 1998 硏究論文集 Vol.16 No.-

컴퓨터를 이용한 유아 교육용 학습 자료의 개발에 많은 관심과 연구로 인해 다양한 학습자료들이 발표되어 있다. 본 논문에서는 패밀리 게임기로 잘 알려진 8비트 게임기와 팩의 스페 분석을 하고, 이를 바탕으로 유아 교육용 프로그램을 구현하였다. 구현된 프로그램은 단계별 유아 교과 내용을 유아들의 학습 수준을 최대한 고려하여 다단계 학습 구조로 구성하였고, 유아 중심의 상호 작용적인 형태를 취함으로써 학습 효과를 한 단계 끌어 올릴 수 있도록 하였다. There are several concerns and researches on the topics of computer assisted learning systems. This paper presents implementing the infant learning program for Family Game Machine from analysis of the Family Pack specification. The programs structurally compose to teach various children. It enables us to raise the effect of learning through a client-oriented design.

재귀 방정식을 이용한 DCT 기반의 반화소 정밀도 움직임 예측 및 보상 알고리듬

류철,강민정 동국대학교 산업기술연구원 2007 산업기술논문집 Vol.17 No.1

공간 영역에서의 움직임 예측 및 보상은 이전 영상에서 지정된 크기의 탐색 영역을 검색하여 현재 블록과 최소 오차를 갖는 블록을 찾는 방법으로, 탐색 영역을 검색하는 과정에서 많은 부호화 시간이 소비된다. 이러한 문제점은 공간 영역에서의 움직임 예측 및 보상을 주파수 영역에서의 이동 행렬을 사용함으로써 해결할 수 있다. 본 논문에서는 기존의 이동 행렬을 새로운 재귀 방정식으로 유도하여 계산량을 더욱 줄이고자 한다. 또한 반화소 정밀도의 움직임 예측 및 보상을 위하여 주파수 영역에서의 수직, 수평 이동 행렬을 간단히 수정함으로써 공간 영역에서의 양선형 보간법에 의해 더욱 증대되는 계산량 문제를 해결하고자 한다. 실험 결과 제안된 알고리듬에 의한 DCT(Discrete Cosine Transform) 기반 주파수 영역에서의 움직임 예측 및 보상이 공간 영역에 비하여 적은 비트량을 이용하여 보다 높은 PSNR(Peak Signal to Noise Ratio)을 제공함으로 증명한다. Motion estimation and compensation in the spatial domain check the searching area of specified size in the previous frame and search block to minimize the difference with current block. When we check the searching area, it consumes the most encoding times due to increasing the complexity. We can solve this fault by means of motion estimation and compensation using shifting matrix in the transform domain instead of the spatial domain. We derive so the existed shifting matrix to a new recursion equation that we decrease more computations. We modify simply vertical shifting matrix and horizontal shifting matrix in the transform domain for motion estimation and compensation of half-pixel accuracy. So, we solve increasing computation due to bilinear interpolation in the spatial domain. Simulation results prove that motion estimation and compensation by the proposed algorithm in DCT-based transform domain provides higher PSNR using fewer bits than results in the spatial domain.

頭鍼이 中風患者의 단기간 NIHSS와 MBI에 미치는 영향

류재춘,박인범,김상우,김철홍,서정철,윤현민,장경전,송춘호,안창범 동의대학교 한의학연구소 2002 동의한의연구 Vol.6 No.-

Objective ; The aim of this study was to investigate the effect of Scalp acupuncture on recovery of motor disorders in stroke patients. Methods ; Twenty two patients with poststroke-hemiplegia were randomized into two groups. Ten patients(test group) treated by 2 methods-Scalp acupuncture and body acupuncture. The other twelve patients(control group) treated only by body acupuncture. The activity of daily living was measured with a National Institutes of Health stroke scale(NIHSS) and Modified Barthel Index(MBI). The therapy was performed one a day for 2 weeks. Results ; In terms of score of NIHSS, the test group showed statistically meaningful decrease after 2 week treatment, but the control group showed statistically meaningful decrease after 1 week(p<0.05). And in terms of score of MBI, the test group did not show statistically meaningful increase but the control group showed statistically meaningful increase after 1 week(p<O.05). There was no statistically meaningful difference after 1 and 2 week treatment between the groups. Conclusions ; These results support that test group has almost same effectness compared with control group in improvement of the activity of daily living of poststroke-hemiplegic patients.

대구지역에서 꿀벌이 수집한 화분의 동정

류장발,장정원,김기만,권외정,김민식,박도규 대구대학교 생명과학연구소 2002 생명과학연구 Vol.1 No.2

Pollens gathered by bees at an apiary at Daegu district were identified with light microscope and scanning electro microscope for effective establishment of honey plant plantations for year-round honey production. Pollen loads were collected from bees from March to October at one week interval, ten loads at each collecting time, a load from a colony. Pollens from fifty-four species were collected and 34 species were identified and 20 species unidentified, which would be identified later. Most of the pollen loads were composed with one species. However, a few loads were composed with up to four species. Pollens of 37 species were collected just one time. Pollens from just one species were not collected at any time. In July pollens from many species, up to six species at July 15 and 20, were collected. Pollens of four species, Erigeron annuus, Lagerstroemia indica, Koelreuteria paniculata, Evodia daniellii, were collected up to one month. As the latter two species were known as good honey producing plants, these two species proved to be good pollen producing plants. The former two species were known as poor honey producing plants, the importance of these two species should be reevaluated.

지방산 유지 원료에 따른 고형비누의 특성에 관한 연구

정명선,배한수,이봉연,민경혜,류덕환 계명대학교 생활과학연구소 2001 科學論集 Vol.27 No.-

The experimental results on the washing efficiency of detergent made from corn oil, wasted cooking oil and pig fat oil are as follows ; Laundry factors in this experiment are detergent concentration, laundry temperature and laundry time. 1.The surface tension of each detergent showed the lowest in 0.2% concentration corn oil 60.84, wasted cooking oil 61.11, pig fat oil 60.73dyne/cm. 2.The wasthing efficiency based on different concentration of detergents showed the highest in 0.2% concentration. 3.The highest washing efficiency appeared in 0.2% concentration 40℃ temperature and 40~50 min. time. There showed no difference in the washing efficiency according to the volume of water. It can be said that the frictional force of bearing rather than the volume of water worked on the efficiency.