한국인 파킨슨병에서 Monoamine Oxidase B 유전자와 Cytochrome P450IID6 유전자의 다형성

이용희,임정근,이상도,이영재 대한신경과학회 1999 대한신경과학회지 Vol.17 No.1

시판 요구르트 Starter의 생리적 특성

임용숙,김순희,이신호 대구효성가톨릭대학교 응용과학연구소 1994 응용과학연구논문집 Vol.3 No.-

시판 호상 요구르트의 품질 검사와 분리된 유산균의 starter특성을 조사한 결과 시판 요구르트의 유산균 수는 9개 회사 시료중 1개 회사가 1.66×10^6CFU/g 을 나타내었고 그외 8개 회사제품은 10^8 ~ 10^9CFU/ml 범위를 나타내었다. 제품의 pH 범위는 4.00 ~ 4.33 으로 비교적 산미가 강하였으며, 적정산도는 1.063 ~ 1.321% 였다. 순수 분리한 요구르트 starter의 산 생성 속도는 배양 시간이 경과함에 따라 적정산도가 모두 증가하는 것으로 나타났다. 특히 배양 12시간째 starter B가 산 생성이 가장 좋았으며, starter E의 산 생성 속도가 가장 늦었다. 9개 회사 starter는 공히 위액과 담즙산에 강한 내성이 관찰되었으며 특히 D, E, G 균주의 경우 위액과 담즙산에 거의 생존하여 가장 내성이 강한 경향을 나타내었다. Viable cells, pH and titrable acidity of nine kinds of marketing gel-type yoghurts and acid production and survival in digestive fluids and bile salts of the isolated starters were investigated. Viable cells of one sample was 1.66×10^6(CFU/g) and other eight samples show-ed about 10^8 to 10^9 (CFU/g). All samples tested had a strong acidic taste with the pH of 4.0 to 4.3 and titrable acidity with 1.063 ` 1.321% lactic acid/ml. Acid production of isolated yoghurt starter increased during incubation. After 12 hr incubation, starter B showed the highest acid pro-duction ability but starter E was the lowest. All of starters were survived in artificial gastric juice and bile salts, especially starter B, E and I showed the strong resistance in artificial gastric juice and bile salts.

Detection of Antibokies to Sendai Virus Using protein G-based ELISA

임윤규,우희종,이영순 濟州大學校 農科大學 動物科學硏究所 1993 動物科學論叢 Vol.8 No.1

We have established an enzyme-linked immunosorbent assay(EL1SA) using enzyme labeled protein G(Protein G-ELISA) to detect Sendai virus-specific antibodies in laboratory animals. Best results were obtained at fl 6.0 of diluent and at 1 to 10 dilution of sera. Antigen concen-tration for solid phase matrix was 5μg /㎖ and the conjugate of horseradish peroxidase (HRP) and prqtein G was used at 1 to 100 dilution. We, also, investigated the sensitivity and speci-ficity of protein G and protein A. Protein C showed relatively high O. D. values than protein A in general. Furthermore, only Protein G-ELISA could detect the Sendai virus specific anti-bodies in rat. though both methods were effective in other species, mouse and guinea pig. No siginificant nonspecific reation was observed at our experimental conditions in both methods.

시판 요구르트 Starter의 생리적 특성

임용숙,김순희,이신호 대구효성가톨릭대학교 식품과학연구소 1994 식품과학지 Vol.6 No.-

시판 호상 요구르트의 품질 검사와 분리된 유산균의 starter 특성을 조사한 결과 시판 요구르트의 유산균 수는 9개 회사 시료중 1개 회사가 1.66×10^6CFU/g을 나타내었고 그외 8개 회사제품은 10^8~10^9CFU/㎖ 범위를 나타내었다. 제품의 pH 범위는 4.00~4.33으로 비교적 산미가 강하였으며, 적정산도는 1.063~1.321%였다. 순수 분리한 요구르트 starter의 산 생성 속도는 배양 시간이 경과함에 따라 적정산도가 모두 증가하는 것으로 나타났다. 특히, 배양 12시간째 starter B가 산 생성이 가장 좋았으며, starter E의 산 생성 속도가 가장 늦었다. 9개 회사 starter는 공히 위액과 담즙산에 대한 내성이 관찰되었으며 특히 D, E, G 균주의 경우 위액과 담즙산에 거의 생존하여 가장 내성이 강한 경향을 나타내었다. Viable cells, pH and titrable acidity of nine kinds of marketing gel-type yoghurts and acid production and survival in digestive fluids and bile salts of the isolated starters were investigated. Viable cells of one sample was 1.66×10^6(CFU/g) and other eight samples showed about 10^8 to 10^9(CFU/g). All samples tested had a strong acidic taste with the pH of 4.0 to 4.3 and titrable acidity with 1.063-1.321% lactic acid/㎖. Acid production of isolated yoghurt starter increased during incubation. After 12 hr incubation, starter B showed the highest acid production ability but starter E was the lowest. All of starters were survived in artificial gastric juice and bile salts, especially starter B, E and I showed the strong resistance in artificial gastric juice and bile salts.

경사도 변화에 따른 트레드밀 역보행의 운동학적 분석

김석희,우병훈,임용규 漢陽大學校 體育科學硏究所 2003 體育科學 Vol.23 No.23

The purpose of this study is to understand special features of back ward walking through 3-dimensional kinematic analysis of backward walking inconsideration of treadmill gradient in 10 male university students in the in twenties and to provide the information required for deciding workload or for preventing injuries. In this stuidy, the walking speed of the treadmill was set at 3.Okm/h and the gradient of the treadmill was set at 0°, 5° and 10°. the APAS were used for the collection of image data and analysis. and one-way ANOVA was used to analyze the differences according to gradients. As there analysis and result show, The first, cadence at 0° was higher than at 5° and 10° The second, support time at 5° was longer than that of 0° and 10°The third, ankle joint displacement became generally low as gradient increased. The fourth, in the knee joint, displacement became higher as gradient increased in the early stage of backward walking. ; however, there was no difference at the later stage. Lastly, no angle displacement of hip joints showed in back ward walking. The study suggests that it will be more desirable to analyze kinetic variables on the backward walking. Therefore it needs the following study for the factor like that continuously.

고령 폐결핵환자(60세 이상)에서의 방사선학적 소견

박정희,진용현,임종남 건국대학교 의과학연구소 1999 건국의과학학술지 Vol.9 No.-

In this elderly patients, incidence of pulmonary tuberculosis is very high because of the decreased function of the body immune system and combined diseases. We analysed radiographic findings of 51 patients with pulmonary tuberculosis to compare with the typical findings of reactivation pulmonary tuberculosis in the adult over 60 years old. The typical location of reactivation pulmonary tuberculosis is the apicoposterior segment of the upper lobe and the superior segment of the lower lobe. But in elderly patients of our study, 38cases(76%) showed lesions also in atypical location such as the anterior segment of the upper lobe, the middle lobe, or the basal segments of the lower lobe. Also 36cases(72%) showed multilobar extents, 30cases(59%) showed unusual findings and 26cases(52%) showed multiple cavities and in 19 cases(38%), differential diagnosis with lung cancer was difficult. Especially in patients with diabetes mellitus, involvement of the anterior segment of the upper lobe was significantly high compared with the patients without DM.

만성폐쇄성 폐질환 환자에서 적혈구 항산화효소의 변화

국기용,이만재,조희충,임영국,박일,김원식,이승일,이병래 朝鮮大學校 附設 醫學硏究所 1993 The Medical Journal of Chosun University Vol.18 No.1

Toxic oxygen free radicals have been implicated as important pathologic mediators in many clinical disordesrs. Enhandng the intracellular content of antioxidant enzymes can provide means of limiting biological damage caused by oxygen free radicals. Many investigations have examined the potential of various oxyradical scavengers to modulate oxyradical injury. The oxygen free radicals play a role in the pathogenesis of chronic obstructive pulmonary disease. To investigate the pulmonary oxyradical injury and the protective role of antioxidant enzymes, author measured the amount of thiobarbituric acid reactants, the activiteies of antioxidant enzymes (superoxide dismutase, glutathione peroxidase, and catalase) and the sulfhydryl groups in serum and red blood cells from the chronic obstructive pulmonary disease groups and the normal controls. The thiobarbituric acid reactant in chronic obstructive pulmonary disease groups was increased than the controls in both serum and red blood cells, and the superoxide dismutase activity in red blood cells was no statistically difference in both groups. But, the glutathione peroxidase and catalase activities were lowered in chronic obstructive pulmonary disease groups than the controls. The sulfhydryl groups in serum and red blood cells were no statistically difference in both groups. These results suggest that the increased thiobarbituric acid reactant in chronic obstructive pulmonary disease groups mean oxygen radical toxicity, and the decreased glutathione peroxidase and catalase activities may play a role in cellular injury.

외배엽 이형성증 환자의 임상적 치험례

오소희,권순원,김종수,김용기,임헌송 대한소아치과학회 2000 大韓小兒齒科學會誌 Vol.27 No.2

Ectodermal dysplasia(외배엽 이형성증)은 외배엽성 기관에 한가지 이상의 선천적 이상소견을 특징으로 하는 질환이다. Ectodermal dysplasia는 약 120종류 이상이 보고되고 있고, 이 중 Hypohidrotic ectodermal dysplasia가 가장 잘 알려져 있으며 이는 성염색체 열성인자에 의해 유전되며 남성에서 호발한다고 한다. 임상증상으로는 무한증, 감모증, 무치증 혹은 핍지증이 가장 특징적이다. 이외에도 무피지증, 손톱이형성증, 가늘고 성긴 머리카락, 두드러진 이마, 안장코, 돌출된 안와상부, 입술의 돌출과 함께 피부가 건조하고 땀샘이 결핍되어 있어서 더위를 참지 못하고 발열이 일어나기 쉽다. 본 증례의 환자는 단국대학교 치과병원 소아치과에 내원한 6세 6개월된 남아로써 무치증을 보이는 Hypohidrotic ectodermal dysplasia로 진단되었고 환자의 심미적, 기능적 결함을 해소하기 위해 총의치로 치료를 시행하는 동안 다소의 지견을 얻어 이를 보고하는 바이다. 주요어 : 외배엽 이형성증, 무치증, 총의치

아몰퍼스 자왜 와이어의 제작과 센서특성

신용진,임재근,조남희 明知大學校 産業技術硏究所 1995 産業技術硏究所論文集 Vol.14 No.-

In this paper, we describe fabrication method and sensing functions of amorphous magnetostrictive wire. (Fe,Co)77Si8B5 chosen as nonstoichometric composition, is melted under high frequency induced furnance and then the melted composition is injection-quenched on water-flow at high speed revolution through the nozzle. As the result amorphous magnetostrictive-wires whose diameters are about 125㎛ are obtained On investigation of characteristics of the amorphous wires, a sharp Matteucci effect occurs even by low external magnetic field. It occurs by large Barkhausen jump due to magnetostriction of the amorphous wire. As the results of experiments, we find that amorphous-wires have sufficient characteristics needed as high sensitive security sensor material.

지구과학의 개념형성학습에 관하여 : 변화에 대한 개념을 중심으로 Especially Concerning to Concepts about Changing Phenomena

姜用熙,林成圭 경북대학교 과학교육연구소 1989 科學敎育硏究誌 Vol.13 No.-

By analyzing Earth Science textbooks currently used in high schools. we tried to establish a basic conceptual system concerning to changing phenomena based on the ESCP's structuralizing scheme. Investigating facts about time and change, we have found 21 basic concepts which should be understood through concept-forming teaching and learning. By classifying the basic concepts to fit the four principles suggested by NSTA as a scientific basic-system. we also tried to generalize the selected concepts. We made test problems in order to test high school students' understanding about earth science concepts especially concerning the changing phenomena in the field of astronomy. Using questionnaire method, we applied the test problems to 160 high school students in Taegu and Kyungpook areas. The results were as follows : the mean score of concept-learned group was 56.0 and that of unlearned group was 48.5. This means that the learned-group had been improved by concept-forming teaching.