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      • 유아의 다중지능 향상을 위한 요리 활동프로그램의 효과 검증

        김혜란 ( Hye Ran Kim ),이경화 ( Kyung Hwa Lee ),서호찬 ( Ho Chan Seo ) 국제뇌교육종합대학원대학교 뇌교육연구소 2014 뇌교육연구 Vol.14 No.-

        본 연구는 유아기의 다중지능 발달의 중요성을 인식하고 유아를 위한 효율적인 교육프로그램을 제공할 수 있는 기초자료를 확보하고자 요리활동 프로그램을 제작하고 적용해봄으로써 요리활동이 유아의 다중지능 향상에 미치는 영향을 알아보는데 교육적 의의를 가진다. 연구의 대상자는 서울시에 소 재한 S유치원의 만 5세 유아 30명을 무선 선정한 후 실험집단과 통제집단에 15명씩 무선 배치하였다. 연구도구는 만 3, 4, 5세를 대상으로 개발하여 표준화시킨 유아 다중지능 검사 도구를 사용하였으며, 수집된 자료는 사전·사후 검사로 t-test를 실시하여 집단 간의 차이를 확인하였다. 8주간의 요리활동으로 실험집단과 통제집단을 비교하여 볼 때 실험집단에서 유아들의 다중지능 향상에 도움을 주었으며 구체적으로 언어 지능, 논리·수학 지능, 시각·공간 지능, 신체운동감각 지능, 음악 지능, 개인이해 지능, 자연탐구 지능에 각각 유 의미한 결과를 나타내었다. 이상과 같은 결과로 요리활동은 유아의 오감을 모두 사용하는 최적의 활동으로 지식이나 기술 습득뿐 아니라 공감과 만족감을 맛볼 수 있다는 점에서 가치 있는 활동으로 제시될 수 있으며 유아 개개인이 지니고 있는 각자의 다 양한 지적 특성에 적합한 교육적 경험의 기회로 요리활동이 활용되어지기를 기대한다. This study has its educational significance in the sense that I have tried to identify the importance of multiple intelligence development during ch ildhood and find out whether or not children``s multiple intelligence can be improved by such programs as cooking activities that have been produced and applied for the purpose of securing basic materials that can provide young children with efficient programs. To attain at its gold of study, I have established the following assumptions and verified its effects. The targets of research were randomly selected from 5-aged 30 children of S kindergarten located in Seoul and 30 of them were arranged into a test group and a control group. The measurement in this research were taken using inspection tools for children``s multiple intelligence developed and standardized for ages of 3, 4, and 5 by Kyung-Hwa Lee. The collected materials have been processed using t-test to find out effect of pre and post-examination through t-test in order to verify significance between those two groups. These are summaries of the result carried out on this study. At first, cooking activities have had impact on children``s linguistic intelligence, showing significant difference statistically, therefore cooking activities having always positive effect on improvement of children``s linguistic intelligence. Second, cooking activities have had impact on children``s logics`` math intelligence, showing significant difference statistically, therefore cooking activities having always positive effect on improvement of children``s logics`` math intelligence. Third. cooking activities have had impact on children``s visual`` spacial intelligence, showing significant difference statistically, therefore cooking activities having always positive effect on improvement of children``s visual`` spacial intelligence. Fourth, cooking activities have had impact on children``s music intelligence, showing significant difference statistically, therefore cooking activities having always positive effect on improvement of children``s music intelligence. Fifth, cooking activities have had impact on children``s inter-personal intelligence, showing significant difference statistically, therefore cooking activities having always positive effect on improvement of children``s inter-personal intelligence. Sixth, cooking activities have had impact on children``s personal understanding intelligence, showing significant difference statistically, therefore cooking activities having always positive effect on improvement of children``s personal understanding intelligence. As a result of taking universal consideration of such results of the study, cooking activities is regarded as a worthy activity not only for acquiring knowledge or technology as an optimal activity that uses all of children``s five senses, but also for experiencing successive feeling and satisfaction. Accordingly, I hope that these cooking activities might be utilized as a educational opportunity from which children enjoy various intellectual characteristics of their own.

      • KCI등재

        마라톤 동호인과 일반인의 체력 및 건강관련 변인의 비교

        김혜란 ( Hye Ran Kim ),이만균 ( Man Gyoon Lee ),성순창 ( Soon Chang Sung ) 한국스포츠정책과학원(구 한국스포츠개발원) 2007 체육과학연구 Vol.18 No.4

        본 연구는 크게 두 가지의 과제로 구성되어 있다. 제 1과제에서는 중년 남성 마라톤 동호인 45명과 운동습관이 없는 일반인 30명을 대상으로 체격 및 체력수준을 비교하였다. 측정항목은 신장, 체중, 신체질량지수, 체지방률, 1200m달리기, 윗몸일으키기, 팔굽혀펴기, 앉아 윗몸앞으로굽히기, 제자리멀리뛰기, 그리고 50m달리기였다. 제 2과제에서는 중년 남성 마라톤 동호인 15명과 운동습관이 없는 일반인 8명을 대상으로 최대산소섭취량, 젖산역치 수준에서의 산소섭취량, 젖산역치 수준에서의 심박수, 1초 강제 호기량, 그리고 혈액변인을 비교하였다. 두 집단의 데이터를 비교하여 분석한 결과를 요약하면 다음과 같다. 1. 마라톤 동호인과 일반인의 체격을 비교한 결과 체중, 신체질량지수, 가슴 피부두겹 두께, 복부와 대퇴 피부두겹 두께, 그리고 체지방률은 마라톤 동호인이 일반인에 비해 유의하게 낮게 나타났다. 2. 마라톤 동호인과 일반인의 체력을 비교한 결과 윗몸일으키기, 팔굽혀펴기, 앉아윗몸앞으로굽히기, 제자리멀리뛰기, 50m달리기, 그리고 1200m달리기 모두 마라톤 동호인이 일반인에 비해 유의하게 높은 것으로 나타났다. 3. 마라톤 동호인과 일반인의 호흡순환계 변인을 비교한 결과는 최대산소섭취량, 최대심박수, 그리고 VO2LT에서 유의한 차이가 나타났다. 그러나 HR(LT), FEV1.0은 유의한 차이가 나타나지 않았다. 4. 마라톤 동호인과 일반인의 대사관련 변인을 비교한 결과 TG, 그리고 HDL-C는 유의한 차이가 나타났으나, 혈중 글루코스, 인슐린, FFA, TC, 그리고 LDL-C에서는 유의한 차이가 나타나지 않았다. 이상의 결과를 종합해 볼 때, 마라톤 동호인이 일반인에 비해 높은 체력 및 건강수준을 갖고 있는 것으로 나타나 마라톤 동호회 활동이 건강 유지 및 증진, 노화의 지연에 긍정적인 효과가 있을 것으로 판단 되어 진다. 따라서 일반인들이 건강한 삶을 위해 마라톤 동호회의 활동에 적극적으로 참여하기 위한 다양한 방법이 강구되어야 할 것으로 사료된다. The purposes of the study were twofold. The first study was designed to compare physical fitness between 45 marathon club participants(MCP) and 30 general individuals(GI) who have not participated in any systematic exercise training before. Test items in the first study included the standing height, body weight, body mass index, percent body fat, 1200m run/walk, sit-up, push up, sit-and-reach, standing long jump, and 50m dash. The second study was designed to compare maximal oxygen consumption, maximal heart rate, oxygen consumption at lactate threshold(VO2LT), heart rate at lactate threshold(HR(LT)), forced expiratory volume in one second(FEV1.0), and blood variables between 15 MCP and eight GI. All data obtained in the two studies were analyzed by independent-t test and the results were as follows: 1) The body weight, body mass index, chest thickness, abdomen thickness, anterior thigh thickness, and percent body fat of MCP were significantly lower than them of GI. 2) Sit-up, push up, sit-and-reach, standing long jump, 50m dash, and 1200m run/walk of MCP were significantly superior than them of GI. 3) There were significant differenced in maximal oxygen consumption, maximal heart rate, and VO2LT between the two groups. However, there was not significant difference in HR(LT), and FEV1.0 between the two groups. 4) There were significant differences in TG, and HDL-C between the two groups, whereas no significant difference was found in blood glucose, insulin, free fatty acid, TC, and LDL-C between the two groups. The aforementioned results indicated that MCP had higher level of physical fitness than them of GI, concluding that the activities in the marathon club could enhance health and physical fitness and prevent aging. The efforts should put for the general individuals into participate sports club activities.

      • KCI등재SCOPUS

        전통누룩 진균류를 이용한 입국의 제조 및 입국곰팡이의 동정

        김재호 ( Jae Ho Kim ),권영희 ( Young Hee Kwon ),이애란 ( Ae Ran Lee ),김혜련 ( Hye Ryun Kim ),안병학 ( Byung Hak Ahn ) 한국균학회 2012 韓國菌學會誌 Vol.40 No.4

        Various koji were prepared by fungi isolated from traditional nuruk and their quality characteristics were investigated. Acidity and saccharification power of their koji were ranged in 5.0~6.8 and 128sp~241sp. Nine fungi which were showed good quality and sensory evaluation were identified by analysis of their nucleotide sequences with PCR-amplified 18S rDNA internal transcribed spacer-1(ITS-1) and ITS-4 genes. Among them, six strains were identified as Aspergillus oryzae and the other strains were identified as Mycocladus corymbiferus, Rhizopus oryzae, Lichtheimia corymbifera.

      • Study on Uranium Adsorption Using Phosphate-Functionalized Silica and Experimental Optimization: Addressing Initial Concentration and pH as Key Factors

        Hye Ran Noh,Suk-Bon Yoon,Tae-Hyeong Kim,Dong-Woo Lee,Sang-hun Lee,Jeongmook Lee,Jong-Yun Kim,Sang Ho Lim 한국방사성폐기물학회 2023 한국방사성폐기물학회 학술논문요약집 Vol.21 No.1

        In this study, we evaluated the performance of phosphate-functionalized silica in adsorbing uranium and provided insights into optimizing the initial conditions of the uranium solution (concentration and pH), which are often overlooked in uranium adsorption studies. While most studies take into account the effect of pH on both the surface charge of the adsorbents and the dissolved speciation of uranium in solution, they often overlook the formation of solid phases such as β-UO2(OH)2 (cr) and UO3· 2H2O(cr), leading to an overestimation of the adsorption capacity. To address this issue, we considered the speciation of U(VI) calculated using thermodynamic data. Our findings suggest that it is reasonable to evaluate the adsorption performance at pH 4 and concentration below 1.35 mM. The formation of β-UO2(OH)2 (cr) starts at 23 μM (pH 5) and 1 μM (pH 6) and increases sharply with increasing concentration. To avoid interference from the formation of solid phases, experiments should be conducted at lower concentrations, which in turn require very small msorbent/Vsolution ratios. However, controlling small amounts of sorbent can be challenging, and increasing the volume of the solution can generate significant amounts of radioactive waste. We also used UV-vis spectra analysis to investigate the formation of solid phases. We found that a 100 mg L-1 uranium solution resulted in the formation of colloidal particles in the solid phase after 2.5 hours at pH 6, while at pH 4, no significant changes in absorbance were observed over 120 hours, indicating a stable ion phase. Based on these conditions, we obtained an excellent adsorption capacity of 110 mg g-1.

      • KCI등재

        Anti-diabetic effect of Ganoderma lucidum assoiated with the activation of AMPK pathway

        Hye Ran Park,Eun-Suk Son,Se-Ra Kim,Yeun-Song Kim,Chang Soo Lee 한국버섯학회 2009 한국버섯학회지 Vol.7 No.4

        The effects of Ganoderma lucidum on glucose uptake was studied in L6 rat skeletal muscle cells. Glucose uptake in muscle cell was increased about 6-fold compared to control by mushroom extract treatment. This increasing effect to the glucose uptake was observed in muscle cells cultured with or without insulin. The levels of phosphor-acetyl CoA carboxylase were upregulated by G. lucidum extract treatment in insulinstimulated and basal culture conditions. However, G. lucidum extract did not affect protein kinaseB/Akt(Akt) level. Furthermore, the expression of phosphor-AMPactivated protein kinase(AMPK) was also up-regulated. AMPK is another regulatory protein in the glucose uptake pathway and energy metabolism. Thus, the treatment of G. lucidum extract in skeletal muscle cells increased the phosphorylation levels of AMPK and acetyl-CoA carboxylase, showing that the increase of glucose uptake by G. lucidum extract might be mediated via the activation of AMPK signaling pathway

      • Synthesis of New Anderson-Type Polyoxometalate With Titanium as a Heteroatom, and Structural Characterization

        Hye Ran Noh,Jong-Yun Kim,Tae-Hyeong Kim,Jeongmook Lee,Jung Hwan Park,Sang Ho Lim 한국방사성폐기물학회 2022 한국방사성폐기물학회 학술논문요약집 Vol.20 No.1

        Polyoxometalates (POMs) are nanoclusters composed of transition metals with high oxidation states. Owing to their redox properties and structural diversity, POMs have been applied to broad fields, such as catalysis, materials, and medicine. Among various fields of application, POMs play an important role in radiochemistry. POMs can form complexes with tri- and tetravalent lanthanides and actinides (radioactive elements), which may be good sequestrators or agents for separating nuclear wastes. Among the most prominent POM structures, Anderson-type POMs with a general formula of [Hy(XO6)M6O18]n? (y=0–6, n=2–8, M=addenda atom, X=heteroatom) represent one of the basic topological structures of the POM family. An important feature of Anderson type POMs is incorporating a large number of various heteroatoms with different size and oxidation states, which can lead to tune chemical properties. Interestingly, no example of Anderson type POMs with early transition metal ions in the heteroatom site has been reported to date. Herein, we discovered that the Anderson POM Na2K6Ti0.92W6.08O24·12H2O, which consists of pure inorganic framework built from a central Ti core supported by six WO6 inorganic scaffold, and the crystal structure was confirmed and refined using single-crystal X-ray diffraction (SC-XRD). In addition, structural characterizations, including, Fourier-transform infrared spectroscopy (FT-IR), X-ray photoelectron spectroscopy (XPS), and Inductively coupled plasma-optical emission spectroscopy (ICP-OES) were performed.

      • KCI등재

        Overexpression of Prohibitin 2 Protein is Associated with Adverse Prognosis in Cytogenetically Normal Acute Myeloid Leukemia

        Lee Young Eun,Lim Ha Jin,Park Ju Heon,Kim Hye-Ran,Kang Min-Gu,조영국,Shin Jong Hee,Shin Myung Geun 대한진단검사의학회 2022 Annals of Laboratory Medicine Vol.42 No.5

        Cytogenetically normal acute myeloid leukemia (CN-AML) accounts for 40%–50% of all AML cases. Despite advances in understanding the molecular pathophysiology of CN-AML, its clinical outcome remains unsatisfactory and unpredictable. To investigate its clinical implication in CN-AML, we measured the expression of prohibitin 2 (PHB2) using immunohistochemical staining (IHCS) of paraffin-embedded bone marrow sections from 134 CN-AML patients. IHCS results were semi-quantitatively scored. Clinical outcome was analyzed in comparison with other prognostic markers, including NPM1 polymorphism and FLT3 internal tandem duplication, and WT1 and BAALC mRNA expression. Except for BAALC mRNA expression, the known molecular markers showed no prognostic effect in the CN-AML patients. PHB2 protein overexpression was significantly associated with adverse prognosis in CN-AML patients. The PHB2 protein expression status may serve as an independent prognostic indicator in CN-AML.

      • SCOPUSKCI등재
      • SCIEKCI등재

        Cloning and Phylogenetic Characterization of Coat Protein Genes of Two Isolates of Apple mosaic virus from ¡?Fuji¡? Apple

        Lee, Gung-Pyo,Ryu, Ki-Hyun,Kim, Hyun-Ran,Kim, Chung-Sun,Lee, Dong-Woo,Kim, Jeong-Soo,Park, Min-Hye,Noh, Young-Mi,Choi, Sun-Hee,Han, Dong-Hyun,Lee, Chang-Hoo The Korean Society of Plant Pathology 2002 Plant Pathology Journal Vol.18 No.5

        Apple mosaic virus (ApMV), a member of the genus Ilarvirus, was detected and isolated from diseased 'Fuji' apple (Malus domestica) in Korea. The coat protein (CP) genes of two ApMV strains, denoted as ApMV-Kl and ApMV-K2, were amplified by using the reverse transcription and polymerase chain reaction (RT-PCR) and were analyzed thereafter. The objectives were to define the molecular variability of genomic information of ApMV found in Korea and to develop virus-derived resistant gene source for making virus-resistant trans-genic apple. RT-PCR amplicons for the APMVS were cloned and their nucleotide sequences were determined. The CPs of ApMV-Kl and ApMV-K2 consisted of 222 and 232 amino acid residues, respectively. The identities of the CPs of the two Korean APMVS were 93.1% and 85.6% at the nucleotide and amino acid sequences, respectively. The CP of ApMV-Kl showed 46.1-100% and 43.2-100% identities to eight different ApMV strains at the nucleotide and amino acid levels, respectively. When ApMV-PV32 strain was not included in the analysis, ApMV strains shared over 83.0% and 78.6% homologies at the nucleotide and amino acid levels, respectively. ApMV strains showed heterogeneity in CP size and sequence variability. Most of the amino acid residue differences were located at the N-termini of the strains of ApMV, whereas, the middle regions and C-termini were remarkably conserved. The APMVS were 17.(1-54.5% identical with three other species of the genus Ilarviyus. ApMV strains can be classified into three subgroups (subgroups I, II, and III) based on the phylogenetic analysis of CP gene in both nucleotide and amino acid levels. Interestingly, all the strains of subgroup I were isolated from apple plants, while the strains of subgroups II and III were originated from peach, hop, or pear, The results suggest that ApMV strains co-evolved with their host plants, which may have resulted in the CP heterogeneity.

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