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Constructing Container Shipping Networks with Empty Container Repositioning among Calling Ports
Koichi SHINTANI,Akio IMAI,Etsuko NISHIMURA,Stratos PAPADIMITRIOU 한국항해항만학회 2006 한국항해항만학회 학술대회논문집 Vol.2 No.-
This paper addresses the design of container liner shipping service networks by explicitly taking into account empty container repositioning and container fleet size. Two key and interrelated issues of deployments of ships and containers are usually treated separately by most existing studies on shipping network design. In this paper, both issues are considered simultaneously. The problem is formulated as a two-stage problem: the upper-problem being formulated as a Knapsack problem and the lower-problem as a Flow problem. A genetic algorithm based heuristic is developed for the problem. Through a number of numerical experiments that were conducted it was shown that the problem considering empty container repositioning provides a more insightful solution than the one without.
Shun Sawatsubashi,Koichi Nishimura,Jinichi Mori,Alexander Kouzmenko,Shigeaki Kato 대한골대사학회 2019 대한골대사학회지 Vol.26 No.1
Vitamin D (VD) is essential for bone health, and VD or its analogues are widely used in clinics to ameliorate bone loss. The targets and mode of VD anti-osteoporotic actions appear to be different from those of other classes of drugs modulating bone remodeling. VD exerts its biological activities through the nuclear VD receptor (VDR)-mediated transcriptional regulation of target mRNA and non-coding RNA genes. VD-induced gene regulation involves epigenetic modifications of chromatin conformation at the target loci as well as reconfiguration of higher-order chromosomal organization through VDR-mediated recruitment of various regulatory factors. Enhancer RNAs (eRNA), a class of non-coding enhancer-derived RNAs, have recently emerged as VDR target gene candidates that act through reorganization of chromatin looping to induce enhancer-promoter interaction in activation of mRNA-encoding genes. This review outlines the molecular mechanisms of VD actions mediated by the VDR and suggests novel function of eRNAs in VDR transactivation.
The Association of Fever with Total Mechanical Ventilation Time in Critically Ill Patients
박동원,Moritoki Egi,Masaji Nishimura,장유진,서기영,임채만,김재열,Keiichi Tada,Koichi Matsuo,Shinhiro Takeda,Ryosuke Tsuruta,Takeshi Yokoyama,김선옥,고윤석 대한의학회 2016 Journal of Korean medical science Vol.31 No.12
This research aims to investigate the impact of fever on total mechanical ventilation time (TVT) in critically ill patients. Subgroup analysis was conducted using a previous prospective, multicenter observational study. We included mechanically ventilated patients for more than 24 hours from 10 Korean and 15 Japanese intensive care units (ICU), and recorded maximal body temperature under the support of mechanical ventilation (MAXMV). To assess the independent association of MAXMV with TVT, we used propensity-matched analysis in a total of 769 survived patients with medical or surgical admission, separately. Together with multiple linear regression analysis to evaluate the association between the severity of fever and TVT, the effect of MAXMV on ventilator-free days was also observed by quantile regression analysis in all subjects including non-survivors. After propensity score matching, a MAXMV ≥ 37.5°C was significantly associated with longer mean TVT by 5.4 days in medical admission, and by 1.2 days in surgical admission, compared to those with MAXMV of 36.5°C to 37.4°C. In multivariate linear regression analysis, patients with three categories of fever (MAXMV of 37.5°C to 38.4°C, 38.5°C to 39.4°C, and ≥ 39.5°C) sustained a significantly longer duration of TVT than those with normal range of MAXMV in both categories of ICU admission. A significant association between MAXMV and mechanical ventilator-free days was also observed in all enrolled subjects. Fever may be a detrimental factor to prolong TVT in mechanically ventilated patients. These findings suggest that fever in mechanically ventilated patients might be associated with worse mechanical ventilation outcome.
Takeguchi Kota,Chantana Jakapan,Nakayama Koichi,Kawano Yu,Nishimura Takahito,Hishikawa Yoshihiro,Minemoto Takashi 한국물리학회 2021 Current Applied Physics Vol.28 No.-
Spectral mismatch correction factor (MM) is determined by average photon energy (APE). APE based on wide solar spectral ranges leads to better description of solar spectral shape. Moreover, error between corrected outdoor short-circuit current (ISC) of PV module and its ISC under standard test conditions is investigated using PV module irradiance sensor (PVMS) and/or MM, where PVMS is a single-crystalline silicon PV module. The error of muti-crystalline silicon (mc-Si) PV module is as low as about 1% regardless of the use of MM attributed to small spectral mismatch between PVMS and mc-Si PV module. On the other hand, the low error of CdTe test PV module is obtained under the use of both PVMS and MM caused by the high spectral mismatch between PVMS and CdTe test PV module. The error is further decreased, when MM is estimated from the APE based on wide ranges of the solar spectrum.
A FULL CHARGE SEPARATION OVER THE TWO SAME CHROMOPHORES IN A PHOTOSYNTHETIC TETRAD
Osuka, Atsuhiro,Marumo, Shinji,Okada, Tadashi,Taniguchi, Seiji,Mataga, Noboru,Ohno, Takeshi,Nozaki, Koichi,Yamazaki, Iwao,Nishimura, Yoshinobu Korean Society of Photoscience 1997 Journal of Photosciences Vol.4 No.3
The synthesis and excited-state dynamics are described for a tetrad (ZC - ZP - ZP - I) consisting of zinc chlorin (ZC), zinc porphyrin (ZP), zinc porphyrin (ZP), and pyromellitimide (I), which upon photoexcitation provides a fully charge-separated state (ZC$^+$- P - ZP - l$^- $) with lifetimes of 230 $\mu$s in THF and > 50$ \mu$s in DMF at room temperature via a stepwise electron-transfer relay that has been detected by the ps-time resolved transient absorption spectroscopy.