직장 Dieulafoy 병변으로 다량의 혈변을 보인 1 예

김태영;이상헌;김지현;배영환;정은주;김승만;지삼룡;설상영 인제대학교 2011 仁濟醫學 Vol.32 No.-

Dieulafoy’s lesion is very rare cause of gastrointestinal bleeding, Deiulafoy’s lesion is exposure of non ulcerative, abnormally large tortuous, thick- walled artery in the muscularis mucosa through a small submucosal defect. It is usullay found on stomach antrum and lesser curvature side of the proximal body, and possibly found on any sites throughout whole gastrointestinal tract, but rarely on rectum. The principal of treating Dieulafoy’s lesion was the surgical resection of lesion, but recently remarkable advances in endoscopic technique make endoscopic approach more popular. We report a case of rectal Dieulafoy’s lesion successfully treated with endoscopic hemoclipping in an elderly female patient.

The level of urinary aflatoxin M1 in Korean adults

Yong-Dae Kim1, Hyojin Kwon, Sun-In Moon, Sang-Yong Eom, Jung-Duk Park, Byung-Sun Choi, Seok-Joon Sohn, Young-Seoub Hong, Ho Kim, Ho-Jang Kwon, Ji-Ae Lim, Hae-Jung Yoon, Gwang-Jin Kim, Heon Kim 충북대학교 동물의학연구소 2012 Journal of Biomedical and Translational Research Vol.13 No.3

Competitive ELISA methods were used to measure the level of aflatoxin M1 (AFM1) from urine in 1008 Korean adults. Subjects were selected by random sampling in all areas of Korea, except Cheju-do. The recovery rate of AFM1 using this method was 105% (73-124%). The geometric mean of urinary AFM1 in all subjects was 3.43 pg/mL (3.67 ng/g creatinine). The level of AFM1 in males was statistically higher, compared with female subjects. However, the levels of AFM1 did not differ according to age. Subjects in Chungbuk-do showed the highest urinary AFM1 concentration, whereas subjects in Kyeongnam-do showed the lowest concentration. Assuming an excretion rate of 5%, this AFM1 excretion corresponds to approximately 0.1 microgram/day in Korean adults.

고삼투압성 비케톤성 상태의 예후인자

안성훈,김양원,김미란,진헌철,안지영,이상래,류석용,김홍용,김성준,이병권,김경환 대한응급의학회 2001 대한응급의학회지 Vol.12 No.2

Background: A hyperosmolar nonketotic state has been known to have a high mortality, and even now, despite this high mortality, only a few studies of this disease have been performed. We studied the prognostic factors for the hyperosmolar nonketotic state. Methods: We retrospectively studied the cases of 40 patients who were in a hypersomolar nonketotic state when admitted to Sanggye Paik Hospital during the 6-year Period from 1995 through 2000. We divided the hyperosmolar nonketotic patients into two groups, the complete recovery group and the incomplete recovery group, and compared the clinical features, the laboratory findings, and the precipitating factors between two groups. Results: 1) A total of 40 patients were studied: 24 in the complete recovery group and 16 patients in the incomplete recovery group. The mortality rate was 32.5%. 2) No significant statistical difference existed among the clinical features of the two groups, except for the sex(p<0.01). 3) Among the laboratory findings of both groups, analysis revealed that the effective osmolarity was significantly higher among those in the incomplete recovery group(p<0.01). Serum sodium concentration was also significantly higher among those in the incomplete recovery group(p<0.01). Serum creatinine was also significantly higher among those in the incomplete recovery group(p<0.05). Serum bicarbonate concentration, on the other hand, was significantly lower among those in that group(p<0.05).4) Infection was identified as the most common precipitating factor(62.5%). Among the precipitating factors of the two groups, there were significant statistical difference in pneumonia, UTI, and inappropriate glucose control. 5) A significant statistical difference existed among the initial level of consciousness of both groups(p<0.05). 6) The only significant independent factor responsible for prognosis of nonketotic hyperosmolar state patients was the sex. Conclusion: The sex was only significant independent prognostic factor of nonketotic hyperosmolar state patients.

'79학년도 본대학 신입생에 대한 학업성적 분석

김정두,윤지헌 영남이공대학 1979 論文集 Vol.8 No.-

This study is one of the continuous work following the preceding analysis in 1977 which has suggested some data in the better improvement of evaluation methods on the students' achievement. Throughout the study, the academic records of 1,699 YJCT freshmen have been used as the reference materials. The main results obtained by this study have revealed the following: First, differences of standard in marking the test scores among the individual course subjects are still existing. Second, the achievement scores of the general selection students for the college admission are higher than the special selection students in the subjects of general education course such as Korean, Ethics, History, English and Mathematics, but contrary lower in the major subjects. Third, the scores for college admission including both Preliminary College Entrance Examination and High School Achievement are not so highly correlated with the college achievement scores as expected. Fourth, no distinct differences have been found according to the years passed after the high school graduation. The college academic achievement scores of the technical high school graduates, however, seemed to be influenced by the reputation of their parent schools. With the above results, it is suggested that a professional study to develop the better selection system of entrance examination, to improve the methods for instruction, evaluation and organization of the course subjects, and to render more effective student guidance should be continued.

열처리가 Teflon^(??) FEP film의 전하보존특성에미치는 영향

김성준,이현석,김지균,권정열,이헌용 명지대학교 산업기술연구소 2007 産業技術硏究所論文集 Vol.26 No.-

In this paper, we studied the method of electrets electrode which formed to accumulate negative electric charges by corona discharges. The breakdown voltage samples and damaged samples by various corona discharges have made material stabilization and improved characteristics of electric charge storage throughout the annealing processes. After the experiment made material stabilization nearly melting point by many kinds of annealing conditions, we did the corona discharge again by the charged high voltages, a discharge electrode gap, and a discharged time. As we compared it with the best condition, we confirmed that characteristics of electric charge storages were improved.

잡음 및 오프셋전압 감소를 위한 종형 홀소자의 교류구동

김정헌,류지구,송명희 釜慶大學校 1998 釜慶大學校 論文集 Vol.3 No.2

In this paper, the Alternating Current(AC) driving method of Vertical Hall Device(VHD) which is sensitive to the magnetic field parallel to the surface of the chip is presented. This system consists of the phase inverting circuit and Low Pass Filter(LPF) ect. for the amplification of Hall voltage and reduction of offset voltage and noise. When this system was operated, the offset voltage and noise could be reduced effetively. Also, the output voltage of VHD was ±74.0〔mV〕 in the low magnetic field ranges of ±100〔Gauss〕, the linearity of output voltage were good, and the magnetic field resolucation was 0.74〔mv/Gauss〕.

증류수와 인공타액에서 충전용 글래스 아이오노머 시멘트의 불소유리량에 대한 평가

김경남,이진숙,류지헌 大韓齒科器材學會 1994 대한치과재료학회지 Vol.21 No.2

The purpose of this study was to compare the amount and pattern of fluoride release from restorative cements into de-ionized water with that in artificial saliva . Three light-curing glass ionomers , a water-setting glass ionomer⁴, two conventional glass ionomers and a resin-based material were selected. Sixteen cylindrical samples(6.5mm×2.5mm)of each cement were prepared. Each was individually suspended in 5ml of either de-ionized water or artificial saliva(eight samples in each medium) and stored at 37℃. The media were changed and fluoride concentration was measured with fluoride electrode for 90 days. The data showed that: (1) Cumulative fluoride release from Ketac-Fil, Dyract and VariGlass VLC into the artificial saliva was significantly less than in de-ionized water(p<0.05) as tested by ANOVA. The cumulative amounts of fluoride into the saliva were 2.52, 0.10 and 0.65 ㎎F /㎤. And they accounts for 49%, 14% and 84% of the amounts into de-ionized water respectively; (2) Ketac-Fil released more fluoride than other materials in both media(p<0.001). Vitremer, Iono Gem, and Dyract released 37%, 38%, and 13% of the cumulative amount of fluoride from Ketac-Fil into deionized water, respectively, but they released 73%, 78%, and 4% of that into artificial saliva, respectively. It is concluded that the release of fluoride from some restorative glass ionomers is highly variable according to the medium in which glass ionomer is stored, and so artificial saliva should be used to test fluoride release of restorative glass ionomer cements.

고체 색소 레이저용 색소 쎌의 제작 및 특성조사

김지훈,이헌주 濟州大學校 基礎科學硏究所 2002 基礎科學硏究 Vol.15 No.2

파장가변레이저로는 일반적으로 파장가변 범위가 넓고 높은 효율을 제공하는 액체 솔루션에 기초한 색소레이저가 쓰이고 있다. 그러나 액체 색소레이저는 부피가 크고, 복잡한 구조로 인한 비싼 가격 등의 단점이 있어, 이를 극복하기 위하여 고체 색소레이저에 대한 많은 연구가 시도되어 왔다. 본 연구에서는 600 nm 근처의 발진파장을 갖는 색소레이저를 위한 고체 색소 쎌을 PolyMethylMathAcrylate(PMMA)를 기반으로 색소의 농도와 두께를 달리하여 주조하였다. LDS 698, Cresyl Violet, Rhodamine 640, DCM 색소를 사용한 고체 색소 쎌에 대해 특성을 조사하였다. 색소쎌의 흡광도와, Nd:YAG 레이저의 제2고조파에 의해 여기된 색소 쎌의 자유방출 스펙트럼에 대한 연구가 이루어졌다. The most widely used tunable lasers are dye lasers based on liquid solutions which can offer wide tuning range and high efficiency. To overcome the drawback of liquid dye laser, such as huge and complicated structure expensive cost, a solid-state dye laser has been developed by many researchers. In this study, solid dye cell was for dye laser was fabricated with PolyMethylMathAcrylate(PMMA). Cells of differential thicknesses and concentration are moulded. Absorbance was measured for the solid-state dye cells with dyes of LDS 698, Cresyl Violet, Rhodamine 640, and DCM. The spontaneous emission spectrum of dye cell excited by 2nd harmonics of Nd:YAG laser were studied.

만성 C형 간염 환자에서 페그인터페론 알파2a와 리바비린 병합 치료중 발생한 벨마비 1예

김일환,장제혁,유충헌,최규남,고정해,김윤정,서광원,김지현,박성재,박은택,이연재,이상혁,설상영 인제대학교 2008 仁濟醫學 Vol.29 No.-

페그인터페론과 리바비린 병합요법은 만성 C형 간염의 일차 치료법이다. 저자들은 만성 C형 간염 환자에서 페그인터페론 과 리바비린 병합 요법 중에 발생한 벨마비 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. 환자는 5년 전부터 만성 C형 간염을 앓아온 48세 남자이며, PEG-IFN α-2a 135μgm 피하주사 주1회와 하루 1200㎎의 리바비린을 투여하였다. 치료시작 후 9개월째 환자는 오른쪽 안면의 근력약화를 호소하였으며 벨마비로 진단되었다. 페그인터페론과 리바비린 병합요법을 지속하면서 관찰하였다. 환자의 벨마비는 페그인터페론 치료를 중단하지 않았음에도 3개월후 증상이 회복되고 이후 벨마비 재발 없이 현재 경과관찰 중이다. 만성 C형 간염에서 페그인터페론과 리바비린 병합 요법시 벨마비의 발생 가능성을 염두에 두어야 하겠다. A Case of Bell's Palsy Associated with Combination Therapy of Pegylated Interferon Alfa-2a (PEG-IFN) and Ribavirin for Chronic Hepatitis C Virus Infection Pegylated interferon alfa(PEG-IFN α) and ribavirin therapy is the first line treatment for chronic hepatitis C. Mild complications of the therapy are common, but more serious complications are rare. We report here a case of Bell's palsy that occurred in a patient with chronic hepatitis C virus infection during combination therapy of PEG-IFN α-2a and ribavirin. The patient was 49-year-old man with chronic hepatitis C (genotype 1b) for 8 years. He had compensated liver cirrhosis with splenomegaly. Therapy with PEG-IFN α- 2a 135mcg/week and ribavirin 1200mg/day was initiated. After 9 months of the therapy, the patient showed a loss of muscular tone on the right side of his face. A diagnosis of Bell's palsy was made. The Bell's palsy resolved over 3 months despite continuation of the combination therapy.

Chloral hydrate/Hydroxyzine과 Midazolam/Meperidine의 경우 투여 진정효과에 관한 비교 연구

김용헌,김지연,박기태 大韓小兒齒科學會 2005 大韓小兒齒科學會誌 Vol.32 No.2

본 연구의 목적은 소아 환자의 치과 진료를 위한 진정요법 시 chloral hydrate와 hydroxyzine의 경구 투여와 midazolam과 meperidine의 경구 투여간의 임상적인 진정효과 및 합병증 발생 여부를 비교하는 것이다. 삼성서울병원 소아치과를 내원한 환아 중 ASA I또는 Ⅱ에 해당하는4세 미만의 아동 15명을 대상으로 하여 한 달여 간격으로 두 차례에 걸친 진정요법을 시행하였다. 2회의 진정요법 중 1회는 chloral hydrate (60mg/kg)/hydroxyzine(25mg)을 경구 투여하고 나머지 1회는midazolam(1mg/kg)/meperidine(1mg/kg)을 경구 투여하였으며 투여 순서는 무작위로 정하였다. 두 차례 모두 N₂O-O₂, 흡입진정을 병용하였다. 각 치료과정에 따른 진정효과는 Houpt Scale(수면, 움직임, 울음, 전반적인 행동 지수)로 측정하였고 pulse oximeter를 이용하여 저산소증의 유무를 비교, 평가하고 약물 투여 후 구토의 여부를 함께 평가하여 다음과 같은 결과를 얻었다. Chloral hydrate와 hydroxyzine을 경구 투여한 군이 midazolam과 meperidine을 경구 투여한 군보다 전반적인 행동 지수에서 통계학적으로 유의하게 우수한 결과를 보였으며 어느 군에서도 저산소증은 보이지 않았다. 본 연구에서는 chloral hydrate와 hydroxyzine의 경구 투여가 midazolam과 meperidine의 경구 투여보다 우수한 진정효과를 보이는 것으로 판단된다. The purpose of this study was to compare the efficacy and complications of two oral sedative regimens, chloral hydrate(60mg/kg)/hydroxyzine(25mg) versus midazolam(1mg/kg)/meperidine(1mg/kg) for the sedation of pediatric dental patients. Fifteen patients(mean age 36.2months, range 24-47months), ASA Class I or II, who needed at least two restorative dental procedures were selected in this double-blind, randomized study. All subjects were randomly assigned to receive either chloral hydrate/hydroxyzine or midazolam/meperidine and 50% N₂O/0₂ was administered at each appointment. Behavior assessment(sleep, movement, crying, overall behavior) was made using Houpt Sedation Rating Scale and physiologic parameters(pulse rate, oxygen saturation) were monitored using pulse oximeter. The incidence of hypoxia(SpO2 90% or less, at least 10s duration) and vomiting was recorded. Patients sedated with chloral hydrate/hydroxyzine showed significantly better overall behavior score than patients sedated with midazolam/meperidine. There was no clinically significant difference in the incidence of hypoxia and vomiting. It was concluded that oral administration of chloral hydrate/hydroxyzine is more effective than midazolam/meperidine for the sedation of pediatric dental patients.