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UGR(Unified Glare Rating)의 보정 및 불쾌글레어 주관평가를 위한 실험적 연구
이진숙,김병수,권혁일 대한건축학회 2003 대한건축학회논문집 Vol.19 No.7
Glare in one of the major factors influencing comfort appraisal for lighting. Although a predictive formula for such glare has been proposed by CIE, it has not been investigated for domestic adjustment. The correlation between glare and the closely related dazzling-sensation has not been investigated enough. In the study, subjective discomfort glare appraisal and dazzling-sensation appraisal for discomfort glare was performed to produce a corrected UGR formula. Analyses between appraisal for dazzling-sensation and results of subjective appraisal for discomfort glare were performed to produce a formula that could represent the correlation between discomfort glare and dazzling-sensation. The results of the comparison and analysis is that results computed by UGR differed from those of subjective perception, so a corrected UGR formula and corrected glare index and dazzling-sensation was produced. Also, a formula that could represent the state of dazzling-sensation verying with change of luminance was produce.
( Byoung Hyuck Kim ),( Eui Kyu Chie ),( Kyu Bo Kim ),( Jin Young Jang ),( Sun Whe Kim ),( Sae Won Han ),( Do Youn Oh ),( Seock Ah Im ),( Tae You Kim ),( Yung Jue Bang ),( Sung W Ha ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: To date, there is a paucity of information regarding optimal radiation dose after microscopic positive (R1) resection in patients with extrahepatic bile duct cancer. This study was conducted to evaluate the impact of radiation dose escalation for R1 resection margin (RM). Methods: A retrospective review was performed on 251 patients who underwent curative resection followed by adjuvant chemoradiotherapy between 1995 and 2009. Eighty-six patients had R1 RM which included invasive carcinoma (n=63) and carcinoma in situ/high-grade dysplasia (n=23). Among them, 54 patients received radiation dose < 54 Gy (range, 40-50.4 Gy) and 32 patients received = 54 Gy (range, 54-56 Gy). Concomitant fi uoropyrimidine-based chemotherapy was administered. Acute and late gastrointestinal (GI) toxicity were evaluated using Radiation Therapy Oncology Group criteria. The median follow-up duration was 27 months for all patients and 92 months for survivors. Results: Radiation dose = 54 Gy was associated with improved locoregional control (LRC) (5yr rate, 73.8% vs. 47.1%, p = 0.038), but not disease-free survival (5yr rate, 43.4% vs. 32.6%, p = 0.427) and overall survival (5yr rate, 40.6% vs. 29.6%, p = 0.393). In multivariate analysis for LRC, R1 with invasive carcinoma (HR 3.31, 95% CI 1.11-9.85, p = 0.032) and radiation dose < 54 Gy (HR 3.09, 95% CI 1.14-8.39, p=0.027) were independent adverse prognostic factors. Between the two dose groups, there was no signifi cant difference in acute GI toxicity =grade 2 and in late GI toxicity =grade 3. Conclusions: The current study demonstrated that radiation dose = 54 Gy was associated with improved LRC in patients with R1 RM and also well tolerated. Therefore, dose escalation could be considered for R1 RM. Prospective study is needed to verify these results.
Byoung Hyuck Kim,Keun-Yong Eom,Jae-Sung Kim,Hyung-Ho Kim,Do Joong Park 대한방사선종양학회 2013 Radiation Oncology Journal Vol.31 No.3
Purpose: To evaluate the role of salvage radiotherapy (RT) for the treatment of regional lymph node recurrence (RLNR) after radical surgery in advanced gastric cancer. Materials and Methods: We retrospectively analyzed medical records of 26 patients who underwent salvage treatment after diagnosis of RLNR between 2006 and 2011. Patients with peritoneal seeding or distant metastasis were excluded. Eighteen patients received RT with or without chemotherapy and the other 8 did chemotherapy only without RT. A three-dimensional conformal RT was performed with median dose of 56 Gy (range, 44 to 60 Gy). Sixteen patients had fluoropyrimidine-based chemotherapy, 5 did taxane-based chemotherapy, and irinotecan was applied in 4. Results: With a median follow-up of 20 months (range, 5 to 57 months), median overall survival (OS) and progression-free survival (PFS) after diagnosis of RLNR were 29 months and 12 months in the entire patients, respectively. Radiotherapy (p = 0.007) and disease-free interval (p = 0.033) were statistically significant factors for OS in multivariate analysis. Median OS was 36 months in patients who received RT and 16 months in those who did not. Furthermore, delivery of RT (p < 0.001), complete remission after salvage treatment (p = 0.040) and performance status (p = 0.023) were associated with a significantly better PFS. Gastrointestinal toxicities from RT were mild in most patients. Conclusion: Salvage RT combined with systemic chemotherapy may be an effective treatment managing RLNR from advanced gastric cancer.
Radiosynthesis and Biodistribution of an <sup>125</sup>I-labeled Resveratrol Derivative
Kim, Sung-Kew,Lee, Woong-San,Han, Sang-Jin,Kim, Eun-Jung,El-Gamal, Mohammed I.,Kim, Byoung-Soo,Choi, Tae-Hyun,Choi, Chang-Woon,Ham, In-Hye,Oh, Chang-Hyun,Choi, Ho-Young,Cho, Jung-Hyuck Korean Chemical Society 2012 Bulletin of the Korean Chemical Society Vol.33 No.2
An $^{125}I$-labeled resveratrol derivative 1 was synthesized. It was purified by reverse phase HPLC. Radiochemical purity of the product was more than 98%, and the yield was 35% (decay-corrected). Its biodistribution in tumorbearing mice was studied. The results showed that the highest radioactivity was located in intestine and stomach. The biodistribution profile suggests that compound 1 can be effectively used as a promising imaging probe for intestine and stomach.
Kim, Byoung Hyuck,Eom, Keun-Yong,Kim, Jae-Sung,Kim, Hyung-Ho,Park, Do Joong The Korean Society for Radiation Oncology 2013 Radiation Oncology Journal Vol.31 No.3
Purpose: To evaluate the role of salvage radiotherapy (RT) for the treatment of regional lymph node recurrence (RLNR) after radical surgery in advanced gastric cancer. Materials and Methods: We retrospectively analyzed medical records of 26 patients who underwent salvage treatment after diagnosis of RLNR between 2006 and 2011. Patients with peritoneal seeding or distant metastasis were excluded. Eighteen patients received RT with or without chemotherapy and the other 8 did chemotherapy only without RT. A three-dimensional conformal RT was performed with median dose of 56 Gy (range, 44 to 60 Gy). Sixteen patients had fluoropyrimidine-based chemotherapy, 5 did taxane-based chemotherapy, and irinotecan was applied in 4. Results: With a median follow-up of 20 months (range, 5 to 57 months), median overall survival (OS) and progression-free survival (PFS) after diagnosis of RLNR were 29 months and 12 months in the entire patients, respectively. Radiotherapy (p = 0.007) and disease-free interval (p = 0.033) were statistically significant factors for OS in multivariate analysis. Median OS was 36 months in patients who received RT and 16 months in those who did not. Furthermore, delivery of RT (p < 0.001), complete remission after salvage treatment (p = 0.040) and performance status (p = 0.023) were associated with a significantly better PFS. Gastrointestinal toxicities from RT were mild in most patients. Conclusion: Salvage RT combined with systemic chemotherapy may be an effective treatment managing RLNR from advanced gastric cancer.
Hyuck-Soo Kim,Byoung-Hwan Seo,Jun-Sik Bae,Won-Il Kim,Chang-Oh Hong,Kwon-Rae Kim 한국토양비료학회 2016 한국토양비료학회지 Vol.49 No.3
This study examined variation in Cd and Pb uptake among different medi cinal plants grown under the same soil environment together with immobilizing effect of lime to decrease these metals accumulation by the medicinal plants. For this, lime was incorporated into a heavy metal-contaminated soil at 1% followed by cultivation of seven different annual and 5 different biennial medicinal plants. In order for comparison, control soil without lime treatment was included and all the pot trials were carried out four replicates. Cadmium and Pb concentrations in medicinal plant roots grown in the control soil varied between 0.5 and 2.8 mg kg<SUP>-1</SUP> for Cd and 3.2 and 82.4 mg kg<SUP>-1</SUP> for Pb. The highest accumulation occurred in C. officinale and the lowest in D. batatas. Lime application decreased average Cd and Pb concentrations in the examined medicinal plants from 1.3 mg kg<SUP>-1</SUP> and 25.7 mg kg<SUP>-1</SUP> to 0.6 mg kg<SUP>-1</SUP> and 11.9 mg kg<SUP>-1</SUP>, respectively in comparison with those grown in the control soil.
Kim, Hyuck-Soo,Seo, Byoung-Hwan,Bae, Jun-Sik,Kim, Won-Il,Hong, Chang-Oh,Kim, Kwon-Rae 한국토양비료학회 2016 한국토양비료학회지 Vol.49 No.3
This study examined variation in Cd and Pb uptake among different medi cinal plants grown under the same soil environment together with immobilizing effect of lime to decrease these metals accumulation by the medicinal plants. For this, lime was incorporated into a heavy metal-contaminated soil at 1% followed by cultivation of seven different annual and 5 different biennial medicinal plants. In order for comparison, control soil without lime treatment was included and all the pot trials were carried out four replicates. Cadmium and Pb concentrations in medicinal plant roots grown in the control soil varied between 0.5 and $2.8mg\;kg^{-1}$ for Cd and 3.2 and $82.4mg\;kg^{-1}$ for Pb. The highest accumulation occurred in C. officinale and the lowest in D. batatas. Lime application decreased average Cd and Pb concentrations in the examined medicinal plants from $1.3mg\;kg^{-1}$ and $25.7mg\;kg^{-1}$ to $0.6mg\;kg^{-1}$ and $11.9mg\;kg^{-1}$, respectively in comparison with those grown in the control soil.
Kim, Hyuck Soo,Seo, Byoung-Hwan,Kuppusamy, Saranya,Lee, Yong Bok,Lee, Jae-Hwang,Yang, Jae-E.,Owens, Gary,Kim, Kwon-Rae Elsevier 2018 Ecotoxicology and environmental safety Vol.148 No.-
<P>The efficiency of gypsum, as a dissolved organic carbon (DOC) coagulator, for the simultaneous immobilization of two heavy metals (Cd and Pb) and one metalloid (As) in agricultural soils near an abandoned mining site was examined. The agricultural soil was defined as long-term contaminated as As (1540 mg kg(-1)), Cd (55 mg kg(-1)) and Pb (1283 mg kg(-1)) concentrations exceeded the Korean guideline values for As (25 mg kg(-1)), Cd (4 mg kg(-1)), and Pb (200 mg kg(-1)). Gypsum was incorporated into the contaminated soil at 3% (w/w). In comparison two commonly using immobilizing agents (lime and compost), together with a mixture (lime + gypsum) were also included in the pot trial for the cultivation of two medical plants (A. gigas and A. macrocephala) and to evaluate the effectiveness of gypsum on As, Cd and Pb immobilization. The results showed that even though pH change-induced immobilizing agents such as lime were more effective than gypsum at immobilizing Cd and Pb, addition of gypsum also effectively reduced heavy metal phytoavailability as indicated by decreases in the concentration of Cd and Pb in medicinal plants. Furthermore, gypsum and gypsum + lime were also most effective in reducing As concentrations in both plants studied. This was mainly attributed to significant decreases in soil DOC (48-64%) when gypsum and gypsum + lime were applied to the soil. Consequently, it was concluded that enhanced DOC coagulation with gypsum, could be considered as a promising technique for the immobilization of both metals (Cd and Pb) and metalloids (As) in agricultural soils.</P>