Landslides Induced by the 2018 Mw6.6 Hokkaido, Japan Earthquake: a Comprehensive Inventory and Relationships with Geological and Seismic Factors

( Jie Dou ),( Hiromitsu Yamagishi ) 대한지질공학회 2019 대한지질공학회 학술발표회논문집 Vol.2019 No.2

On 5 September 2018 (UTC), the Mw=6.6 earthquake in Atsuma town, Hokkaido, Japan induced more than 10,000 landslides with high density, causing substantial economic losses and casualties, which provides a significant opportunity to advance understanding of the spatial distribution and controls for the landslide occurrence triggered by large earthquakes. A detailed, comprehensive inventory of landslides scarps was constructed using the high-resolution aerial photographs and 2 m Lidar DEM data. In total, 10133 landslide scarps were mapped, and the area of landslide scarp is 14.82 km2. The events are densely distributed in the study area. Statistical analysis of the landslide database was carried out. The correlations between coseismic landslide occurrence and geological factors and seismic factors were identified. The results indicate that ridge, geological factors, and seismic factor mainly control coseismic landslide occurrence. These findings are significant to deliberate in future seismic landslide hazard analysis.

Trichoderma biodiversity in major ecological systems of China

Kai Dou,Jinxin Gao,Chulong Zhang,Hetong Yang,Xiliang Jiang,Jishun Li,Yaqian Li,Wei Wang,Hongquan Xian,Shigui Li,Yan Liu,Jindong Hu,Jie Chen 한국미생물학회 2019 The journal of microbiology Vol.57 No.8

An investigation of Trichoderma biodiversity involving a large-scale environmental gradient was conducted to understand the Trichoderma distribution in China. A total of 3,999 isolates were isolated from forestry, grassland, wetland and agriculture ecosystems, and 50 species were identified based on morphological characteristics and sequence analysis of genetic markers. Trichoderma harzianum showed the largest proportion of isolates and the most extensive distribution. Hypocrea semiorbis, T. epimyces, T. konilangbra, T. piluliferum, T. pleurotum, T. pubescens, T. strictipilis, T. hunua, T. oblongisporum and an unidentified species, Trichoderma sp. MA 3642, were first reported in China. Most Trichoderma species were distributed in Jilin and Heilongjiang Provinces in northeast China and the fewest were distributed in Qinghai Province. Based on the division of ecological and geographic factors, forestry ecosystems and low-altitude regions have the greatest species biodiversity of Trichoderma.

Prevalence, Risk Factors, and Psychological Effects of Primary Nocturnal Enuresis in Chinese Young Adults

Hui Jie Hu,Zhen Wei Zhang,Yu Liang,Yan Yan Luo,Qi Feng Dou,Cui Ping Song,Hui Min Zhang,Ying Zhao,Guang Run Tian,Ke Zhang,Qiu Fang Mao,Jing Gui Song,Soren Rittig,Jian Guo Wen 대한배뇨장애요실금학회 2021 International Neurourology Journal Vol.25 No.1

Purpose: This study aimed to investigate the prevalence, risk factors, and effects of primary nocturnal enuresis (PNE) on physical and mental health in young adults in mainland China. Methods: An anonymous questionnaire was used to collect information including the sociodemographic characteristics, history of PNE, family history, daytime voiding symptoms, Pittsburgh Sleep Quality Index (PSQI) scores, Self-Esteem Scale (SES), and Self-Rating Depression Scale (SDS). A total of 22,500 university students from 23 provinces and 368 cities in mainland China were included. Results: In total, 21,082 questionnaires were collected, and 20,345 of them qualified for statistical analysis. The PNE prevalence was 1.17%, and the distribution of monosymptomatic nocturnal enuresis (MNE) and nonmonosymptomatic nocturnal enuresis (NMNE) was 66.1% and 33.9%, respectively. In total, 28% of respondents with PNE reported bedwetting daily, 31.6% between 1 and 7 times weekly, and 40.4% between 1 and 4 times monthly; 80% of PNE cases had no history of treatment. The prevalence of PNE in patients with a family history, frequency, urgency, urinary incontinence, and recurrent urinary tract infections was significantly higher than in those without these conditions (P<0.001). PNE was significantly correlated with the PSQI total score (sleep quality) (P=0.011). The SES score was lower and the SDS was higher (P<0.001) in the PNE group than in those without PNE. Conclusions: In mainland China, the PNE prevalence among young adults was found to be high, and PNE had significant effects on physical and mental health. Risk factors included a family history, daytime voiding symptoms, and lack of treatment.

Dynamic self-collision detection and prevention for 2-DOF robot arms using interval-based analysis

Hao Fang,Jie Chen,Lihua Dou 대한기계학회 2011 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.25 No.8

The problems related to self-collision detection and optimal collision-free trajectory planning for a robot arm subjected to dynamic constraints is investigated. First, a computed-torque method is used to obtain a linearized closed-loop system. For this linearized system,the reference state that the robot arm is capable of reaching is verified through phase plane analysis. This will ensure that the robot arm can be stopped before self-collision occurs. Dynamic constraints are taken into account for a continuous motion of deceleration by calculating the bounds of the commanded force/torques with interval evaluations. When the reference state at t+δt is not valid for selfcollision avoidance, a new feasible state is determined by adhering to an interval-based method which allows decomposition of a complex constrained optimization problem into a simple two-stage optimization problem with relaxed constraints. The optimized feasible state not only secures the robot arm against self-collision but also allows the robot arm to track the original reference trajectory closely. Simulation and experimental results of a 2-dof robot arm show the effectiveness of the proposed interval-based approach.

Betulin Targets Lipin1/2-Meidated P2X7 Receptor as a Therapeutic Approach to Attenuate Lipid Accumulation and Metaflammation

( Jia-yi Dou ),( Yu-chen Jiang ),( Zhong-he Hu ),( Kun-chen Yao ),( Ming-hui Yuan ),( Xiao-xue Bao ),( Mei-jie Zhou ),( Yue Liu ),( Zhao-xu Li ),( Li-hua Lian ),( Ji-xing Nan ),( Yan-ling Wu ) 한국응용약물학회 2022 Biomolecules & Therapeutics(구 응용약물학회지) Vol.30 No.3

The present study focused on the potential mechanism of betulin (BT), a pentacyclic triterpenoid isolated from the bark of white birch (Betula pubescens), against chronic alcohol-induced lipid accumulation and metaflammation. AML-12 and RAW 264.7 cells were administered ethanol (EtOH), lipopolysaccharide (LPS) or BT. Male C57BL/6 mice were fed Lieber-DeCarli liquid diets containing 5% EtOH for 4 weeks, followed by single EtOH gavage on the last day and simultaneous treatment with BT (20 or 50 mg/kg) by oral gavage once per day. In vitro, MTT showed that 0-25 mM EtOH and 0-25 μM BT had no toxic effect on AML-12 cells. BT could regulate sterolregulatory-element-binding protein 1 (SREBP1), lipin1/2, P2X7 receptor (P2X7r) and NOD-like receptor family, pyrin domains-containing protein 3 (NLRP3) expressions again EtOH-stimulation. Oil Red O staining also indicated that BT significantly reduced lipid accumulation in EtOH-stimulated AML-12 cells. Lipin1/2 deficiency indicated that BT might mediate lipin1/2 to regulate SREBP1 and P2X7r expression and further alleviate lipid accumulation and inflammation. In vivo, BT significantly alleviated histopathological changes, reduced serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) and triglyceride (TG) levels, and regulated lipin1/2, SREBP1, peroxisome proliferator activated receptor α/γ (PPARα/γ) and PGC-1α expression compared with the EtOH group. BT reduced the secretion of inflammatory factors and blocked the P2X7r-NLRP3 signaling pathway. Collectively, BT attenuated lipid accumulation and metaflammation by regulating the lipin1/2-mediated P2X7r signaling pathway.

Association Between Nasal Colonization of Staphylococcus aureus and Eczema of Multiple Body Sites

Guo Yang,Dou Xia,Chen Xiao-Fan,Huang Cong,Zheng Ying-Jie,Yu Bo 대한천식알레르기학회 2023 Allergy, Asthma & Immunology Research Vol.15 No.5

Purpose: Staphylococcus aureus is the critical pathogenic bacterium of eczema. The relationship between nasal colonization by S. aureus and eczema has not been well studied. We aimed to evaluate the associations between nasal colonization by S. aureus and eczema of multiple body sites, including persistent and ever-reported eczema. We further examined the associations between eczema and different subtypes of S. aureus, that is, methicillin-resistant S. aureus (MRSA) and methicillin-sensitive S. aureus (MSSA). Methods: The real-world data from the US National Health and Nutrition Examination Survey were used. The associations were calculated using survey-weighted multinomial logistic regression models and further calculated in subgroups stratified by demographic factors. Results: In total, 2,941 adults were included. The prevalence rate of S. aureus nasal carriage was significantly higher in adults with persistent hand eczema (51.0%) than in those with ever-reported hand eczema (23.3%) and never eczema (26.9%). S. aureus nasal colonization was associated with an approximately two-fold increased risk of persistent hand eczema (odds ratios ranges in different models: 2.86–3.06) without significant heterogeneity in the association by demographic factors. No significant associations between S. aureus nasal colonization and persistent eczema of other body sites or ever-reported eczema of multiple body sites (including hands) were observed. Furthermore, similar significant association between nasal colonization of MSSA and persistent hand eczema was seen; the association was much stronger (odds ratios ranges in different models: 4.64–6.54) for MRSA, although with borderline significant. Conclusions: Nasal colonization of S. aureus was associated with increased risk of persistent hand eczema. Our findings imply that preventive measures targeting S. aureus for the anterior nares should be considered in preventing and treating eczema.

From WiFi to WiMAX: Efficient GPU-based Parameterized Transceiver across Different OFDM Protocols

( Rongchun Li ),( Yong Dou ),( Jie Zhou ),( Baofeng Li ),( Jinbo Xu ) 한국인터넷정보학회 2013 KSII Transactions on Internet and Information Syst Vol.7 No.8

Orthogonal frequency-division multiplexing (OFDM) has become a popular modulation scheme for wireless protocols because of its spectral efficiency and robustness against multipath interference. Although the components of various OFDM protocols are functionally similar, they remain distinct because of the characteristics of the environment. Recently, graphics processing units (GPUs) have been used to accelerate the signal processing of the physical layer (PHY) because of their great computational power, high development efficiency, and flexibility. In this paper, we describe the implementation of parameterized baseband modules using GPUs for two different OFDM protocols, namely, 802.11a and 802.16. First, we introduce various modules in the modulator/demodulator parts of the transmitter and receiver and analyze the computational complexity of each module. We then describe the integration of the GPU-based baseband modules of the two protocols using the parameterized method. GPU-based implementations are addressed to explain how to accelerate the baseband processing to archive real-time throughput. Finally, the performance results of each signal processing module are evaluated and analyzed. The experiments show that the GPU-based 802.11a and 802.16 PHY meet the real-time requirement and demonstrate good bit error ratio (BER) performance. The performance comparison indicates that our GPU-based implemented modules have better flexibility and throughput to the current ones.

Isotopic Characterization of Biomass Carbon Incorporation into Soil Aggregates

Song Guan,Sen Dou,Guang Chen,Gang Wang,Jie Zhuang 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6

BF-30 effectively inhibits ciprofloxacin-resistant bacteria in vitro and in a rat model of vaginosis

Jing Wang,Bing Li,Yang Li,Jie Dou,Qingru Hao,Yuwei Tian,Hui Wang,Changlin Zhou 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.7

Bacterial infections are becoming increasinglydifficult to treat due to the increasing number of multidrugresistantstrains. Cathelicidin-BF (BF-30) is a cathelicidinlikeantimicrobial peptide and exhibits broad antimicrobialactivity against bacteria. In the present study, the antibacterialactivity of BF-30 against ciprofloxacin-resistantEscherichia coli and Staphylococcus aureus was examined,and the protective effects of this peptide against these bacteriain rats with bacterial vaginosis were identified for thefirst time. The data showed that BF-30 had effective antimicrobialactivities against ciprofloxacin-resistant E. coliand S. aureus. The minimal inhibitory concentrations forboth bacterial strains were 16 lg/ml, and the minimal bactericidalconcentrations were 64 and 128 lg/ml, respectively. A time course experiment showed that the CFUcounts rapidly decreased after BF-30 treatment, and thebacteria were nearly eliminated within 4 h. BF-30 couldreduce the fold change (CFU/ml) in local colonization bydrug-resistant E. coli and S. aureus to 0.01 at a dose of0.8 mg/kg/day in the rats’ vaginal secretions. In addition,BF-30 induced membrane permeabilization and bound to thegenomic DNA, interrupting protein synthesis. Taken together,our data demonstrate that BF-30 has potential therapeuticvalue for the prevention and treatment of bacterialvaginosis.

Prevalence, Risk Factors, and Psychological Effects of Overactive Bladder in Chinese University Students

Yu Liang,Guo Wei Si,Hui Jie Hu,Zhen Wei Zhang,Cui Ping Song,Qi Feng Dou,Jian Guo Wen 대한배뇨장애요실금학회 2022 International Neurourology Journal Vol.26 No.4

Purpose: The purpose of this study was to investigate the prevalence and risk factors of overactive bladder (OAB) in young adults and to explore the influence of OAB on mental health. Methods: Between October 2019 and January 2020, 14,010 anonymous questionnaires were distributed to freshmen at 2 universities in Henan, China. The students came from all over the country. The questionnaire included general items and information necessary to calculate the overactive bladder symptom score, the Chinese version of the Pittsburgh Sleep Quality Index (PSQI) score, Self-Esteem Scale (SES) score, and Self-Rating Depression Scale (SDS) score. The relationships between the prevalence of OAB and its risk factors were evaluated. Results: The overall prevalence of OAB was 6.0%, with 4.3% of participants characterized as having dry OAB and 1.7% as having wet OAB. The prevalence of mild OAB was 5.5%, and that of moderate OAB was 0.5%; no severe OAB was observed. Higher prevalence rates of OAB were found among women, respondents with constipation, and respondents with primary nocturnal enuresis (PNE) (P <0.05). Compared to healthy controls, the OAB group exhibited a higher mean SDS score (52.12±8.986 vs. 47.71±9.399, P<0.001) and mean PSQI score (5.28±2.486 vs. 4.27±2.431, P<0.001), but a lower mean SES score (27.78±3.599 vs. 29.57±4.109, P<0.001). Conclusions: OAB significantly affects the mental health of young adults. Female sex, constipation, and PNE are risk factors for OAB.