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- 저자 : ( Jinbo Xu ) (검색결과 4 건)
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Ni, Jinbo,Xu, Feng,Gao, Juan Korean Mathematical Society 2013 대한수학회지 Vol.50 No.1
In this paper, we investigate the existence and controllability results for a class of abstract stochastic evolution differential inclusions with nonlocal conditions where the linear part is nondensely defined and satisfies the Hille-Yosida condition. The results are obtained by using integrated semigroup theory and a fixed point theorem for condensing map due to Martelli.
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Virus-like Particles as Antiviral Vaccine: Mechanism, Design, and Application
Lei Zhang,Wen Xu,Xi Ma,XiaoJing Sun,JinBo Fan,Yang Wang 한국생물공학회 2023 Biotechnology and Bioprocess Engineering Vol.28 No.1
Virus-like particles (VLPs) are viral structural protein that are noninfectious as they do not contain viral genetic materials. They are safe and effective immune stimulators and play important roles in vaccine development because of their intrinsic immunogenicity to induce cellular and humoral immune responses. In the design of antiviral vaccine, VLPs based vaccines are appealing multifunctional candidates with the advantages such as self-assembling nanoscaled structures, repetitive surface epitopes, ease of genetic and chemical modifications, versatility as antigen presenting platforms, intrinsic immunogenicity, higher safety profile in comparison with live-attenuated vaccines and inactivated vaccines. In this review, we discuss the mechanism of VLPs vaccine inducing cellular and humoral immune responses. We outline the impact of size, shape, surface charge, antigen presentation, genetic and chemical modification, and expression systems when constructing effective VLPs based vaccines. Recent applications of antiviral VLPs vaccines and their clinical trials are summarized.
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Xiaoying Li,Xianhui Cheng,Baosheng Liao,Jiang Xu,Xu Han,Jinbo Zhang,Zhiwei Lin,Lianghai Hu 고려인삼학회 2021 Journal of Ginseng Research Vol.45 No.1
Background: Panax ginseng, as one of the most widely used herbal medicines worldwide, has been studied comprehensively in terms of the chemical components and pharmacology. The proteins from ginseng are also of great importance for both nutrition value and the mechanism of secondary metabolites. However, the proteomic studies are less reported in the absence of the genome information. With the completion of ginseng genome sequencing, the proteome profiling has become available for the functional study of ginseng protein components. Methods: We optimized the protein extraction process systematically by using SDS-PAGE and one-dimensional liquid chromatography mass spectrometry. The extracted proteins were then analyzed by two-dimensional chromatography separation and cutting-edge mass spectrometry technique. Results: A total of 2,732 and 3,608 proteins were identified from ginseng root and cauline leaf, respectively, which was the largest data set reported so far. Only around 50% protein overlapped between the cauline leaf and root tissue parts because of the function assignment for plant growing. Further gene ontology and KEGG pathway revealed the distinguish difference between ginseng root and leaf, which accounts for the photosynthesis and metabolic process. With in-deep analysis of functional proteins related to ginsenoside synthesis, we interestingly found the cytochrome P450 and UDP-glycosyltransferase expression extensively in cauline leaf but not in the root, indicating that the post glucoside synthesis of ginsenosides might be carried out when growing and then transported to the root at withering. Conclusion: The systematically proteome analysis of Panax ginseng will provide us comprehensive understanding of ginsenoside synthesis and guidance for artificial cultivation.
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From WiFi to WiMAX: Efficient GPU-based Parameterized Transceiver across Different OFDM Protocols
( Rongchun Li ),( Yong Dou ),( Jie Zhou ),( Baofeng Li ),( Jinbo Xu ) 한국인터넷정보학회 2013 KSII Transactions on Internet and Information Syst Vol.7 No.8
Orthogonal frequency-division multiplexing (OFDM) has become a popular modulation scheme for wireless protocols because of its spectral efficiency and robustness against multipath interference. Although the components of various OFDM protocols are functionally similar, they remain distinct because of the characteristics of the environment. Recently, graphics processing units (GPUs) have been used to accelerate the signal processing of the physical layer (PHY) because of their great computational power, high development efficiency, and flexibility. In this paper, we describe the implementation of parameterized baseband modules using GPUs for two different OFDM protocols, namely, 802.11a and 802.16. First, we introduce various modules in the modulator/demodulator parts of the transmitter and receiver and analyze the computational complexity of each module. We then describe the integration of the GPU-based baseband modules of the two protocols using the parameterized method. GPU-based implementations are addressed to explain how to accelerate the baseband processing to archive real-time throughput. Finally, the performance results of each signal processing module are evaluated and analyzed. The experiments show that the GPU-based 802.11a and 802.16 PHY meet the real-time requirement and demonstrate good bit error ratio (BER) performance. The performance comparison indicates that our GPU-based implemented modules have better flexibility and throughput to the current ones.
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