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      • SCIESCOPUSKCI등재

        인삼(Panax ginseng C.A. Meyer) 신품종 고풍의 육성경과 및 생육특성

        권우생(Woo-Saeng Kwon),이장호(Jang-Ho Lee),박찬수(Chan-Soo Park),양덕춘(Deok-Chun Yang) 고려인삼학회 2003 Journal of Ginseng Research Vol.27 No.2

        To develop a new ginseng variety with good quality and high yielding, a lot of individual ginseng plant were selected in the farmers' fields in 1968. Among them, a promising line, 680-83-4, has been developed through comparative cultivation of several lines selected with pure line separation from local races in KT&G Central Research Institute, preliminary and advanced yield trials were performed for 8 years. 680-83-4 was designated as KG103, which was then registered as a new variety “Gopoong” with the regional yield and adaptation trials for 10 years (1981-1990) on December<br/> 27, 2000 in Korea. Gopoong has different phenotype of a dark violet stem and dark red fruit and inverted triangle shape of berries cluster as compared with other varieties. Taproot of Gopoong was longer than local race Jakyungjong, and root yield was 4.5% higher than local race Jakyungjong. In red ginseng quality, the rates of Chun-Jeesam grade(Chun and Jee means 1st and 2nd grade, respectively) were 16.6% and 9.4% for Gopoong and Jakyungjong, respectively. In these results, it was that Gopoong was superior ginseng line with good quality for manufacture of red ginseng.

      • KCI등재

        조직과 문화의 관점에서 접근한 한국형 지식경영 모델 : IMF 사태에 대한 사례 분석을 중심으로 A case study of the IMF stand-by arrangement in Korea

        전기정,현우식,장승권 한국생산성학회 1999 生産性論集 Vol.13 No.3

        Using the knowledge management perspective, this study investigates the top level decision making process, which brought the financial crisis in Korea at late 1997. To analyze the characteristics of a Korean knowledge management, this study applies knowledge spaces for meta-knowledge, formalhformal organizations, and cultural spaces. Implicit knowledge and the role of informal organizations are regarded to be relatively more important in Korean knowledge management models. It, then, suggests the introduction of meta-knowledge mechanisms for the fluent circulation of knowledge.

      • 압출성형에 의한 국산 무연탄 활성탄의 세공구조 변화

        이송우,문장천,김도한,이창한,최동훈,류동춘,송승구 부산대학교 환경문제연구소 2000 環境硏究報 Vol.18 No.-

        The purpose of this study is to investigate the variation of pore size distribution of the coal-based extruded activated carbon. The extruded activated carbon was prepared by extruding the mixture of coal powder and coal tar. Pore size distribution of the extruded activated carbon was compared with that of the extruded coal and the extruded char. Also it was compared with that of the crushed activated carbon, raw coal and char. The extruded coal had coarser surface than that of raw coal. Macropores of the extruded coal were funned near 10,000Å in diameter during carbonization process and steam penetrated easily between particles and were growing between 3,000Å and 20,000Å in diameter during activation process.

      • 70계열 알루미늄합금 용접부의 피로균열진전 거동과 피로수명 예측에 관한 연구

        옹장우,김재훈,정근춘 忠南大學校 産業技術硏究所 1988 산업기술연구논문집 Vol.3 No.1

        It has been important to determine life cycle and stress range for the each welded metal under high cycle load control test conditions. In this study, fatigue crack propagation rate for 7017, 7020, 7039 and 5083 alluminum welded alloy was compared with stress intensity factor range linear elastic fracture mechanics. Compact tension specimens were used and crack growth rate da/dN and stress intensity factor range ΔK were analyzed concerning to the R value of 0.1 and 0.3. In order to find out the value of ΔK, ΔK-inceasing test method was applied by the standard fatigue testing method describes in ASTM E647-81. From the result, the stable crack propagation region of 7017, 7020, 7039 and 5083 alluminum welded alloy was applicable to the Paris equation da/dN = C(ΔK)m (C and m are material constants). Constant m decreases and constant C increases with increasing of stress ratio R. Without dependence on materials, the fatigue life and the propagation rate increase, while the gradients of crack propagation rate decrease, whith increasing stress ratio. Fatigue life was observed roughly in the order of 7020 > 5083 > 7017 > 7039, independently on crack propagation direction and stress ratio. The fatigue life is longer when the crack propagation direction of specimen and welded bead are parallel to each other than transverse. The crack propagation rate and the gradient of it are larger in the case of parallel specimen than transverse. The minimum crack length of fatigue life can be estimated through the knowledge of maximum equivalent crack length obtained by using nondestructive test.

      • 디지탈 시냅스의 구현에 관한 연구

        朴仁政,張虎聲,李天雨,金泰亨 단국대학교 1993 論文集 Vol.27 No.-

        The conventional computer has the excellent performances in data management and numerical calculation, but it has reached limitation in a field of parallel processing such as image and speech processing. Neural networks have been studied in order to overcome this limitation. Recently, neural processor has been developed up to the level of the chip. Neural networks are composed of the connection of unit cells which have functions of multiplication, addition and transformation. In this paper a neural network is designed in digital method which easily adjusts weights and fabricated with an EPLD device.

      • 초고층 주거건축의 공간환경에 따른 거주의식 비교 연구 : 주상복합형아파트와 단지형아파트 거주자의 만족도 분석을 중심으로 focused on dweller's staisfaction analysis of mult-used apartments and housing complex apartments

        추영욱,윤장우,박춘근 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1

        The result that compare and analysis dwelling consciousness to space environment of apartment complex is as follow. Development of super highrise residential construction is enlivening in Busan. This is differented by multi-used apartments and housing complex apartments, and is in super highrise trend. Housing complex apartments appear higher satisfaction than multi-used apartments in dwelling generally. It was analyzed multi-used apartments are very poor in habitability and living environment side. Resident's improvement request is preferential request for convenient facilities. And while the improvement request about ventilation and lighting is higher in multi-used apartments, improvement request about outside view is higher in housing complex apartments.

      • KCI등재후보

        일개 대학병원근무자들에서의 인플루엔자 예방 접종 순응도 관련요인

        정희진,손장욱,최선주,엄중식,우흥정,천병철,김우주,박승철 대한감염학회 2004 감염과 화학요법 Vol.36 No.4

        목적 : 병원근무자에서의 인플루엔자 예방 접종은 병원내에서 인플루엔자 전파를 막기위한 수단으로 적극 권장되고 있으나 매년 인플루엔자 백신을 접종하는 병원근무자들은 소수에 지나지 않는다. 본 연구는 병원근무자들에서의 인플루엔자 예방 접종률을 향상시키기 위한 목적으로 첫째, 백신 접종자에서의 인플루엔자 백신 접종 계기를 알아보고 둘째, 인플루엔자 백신접종의 장애요인을 분석하여 그 문제점을 해결하는데에 목표가 있다. 재료 및 방법 : 서울 1개 대학병원의 병원종사자들을 대상으로 1999년 10월 1개월에 걸쳐 인플루엔자 예방 접종을 하도록 한 후 2000년 3월에 접종군과 비접종군을 대상으로 구조화된 설문지를 이용한 설문조사를 실시하였다. 백신 접종군을 대상으로 백신접종의 동기(que to action), 비접종군을 대상으로는 접종에의 장애요인(barrier) 등을 조사하였다. 이 외에도 양군을 대상으로 인플루엔자에 대한 지식 척도, 인플루엔자 백신으로 기대되는 효과(benefit)등에 대한 설문조사를 시행한 후 정답률을 조사하였다. 결과 : 1) 설문 조사에 응한 총 수는 309명으로 간호사가 60% 이상이었다. 백신접종군은 평균연령, 평균 근무연수가 비접정군에 비하여 유의하게 길었으나 성별, 직종별 분포는 양 군간 차이가 없었다. 2) 인플루엔자 예방 접종의 필요성에 대한 지식정도에 있어 접종군의 934%가 그 필요성을 잘 인식하여 비접종군의 779%보다 유의하게 높았으나 예방 접종이 필요한 구체적 이유에 대한 정확한 이해는 접종군 113%, 비접종군 119%에 불과하였다. 3) 인플루엔자 예방 접종을 받은 의료인들의 행동계기는 ‘감염관리실의 홍보’와 ‘주위사람들의 권유’에 의한 경우가 26.9%, 21.6%로 가장 많았고 본인이나 가족, 친구들을 통한 일종의 감지된 위협 때문에 접종한 경우 31명(186%)의 순이었다. 4) 비접종자들에서 예방 접종을 시행치 않은 가장 흔한 이유는 ‘업무에 바쁘고 시간이 없어서’라는 항목이었으며(37.3%) 특히 의사 집단에서는 이러한 이유가 68.8%로서 압도적으로 많았다. 간호사나 기타 직종에 종사하는 직원들의 경우는 자신의 건강에 대한 확신이 30%내외에 달하였고 예방 접종 자체의 효과에 의문을 갖는 경우도 직종에 따라 6.3-29.7%에 달하였다. 결론 : 병원근무자에서 인플루엔자 예방 접종률을 향상시키기 위해서는 백신 접종의 장애물(효과의 의문, 부작용)을 효과적으로 제거하고 인플루엔자 백신의 필요성과 효과를 인식시키기 위한 교육과 함께 시간, 공간상의 제약을 배제할 수 있는 접근성의 문제를 해결하여야 할 것으로 사료된다. Background : In spite of yearly recalls, influenza immunization rate among healthcare workers (HCWs) remained low in Korea University Guro Hospital. This study was conducted to identify the causes of non-compliance against influenza immunization and to analyze the barrier factors for the immunization. Materials & Methods : Questionnaires were distributed in March of 2000 at Korea University Guro Hospital. We evaluated factors associated with acceptance of influenza vaccination and opinions regarding influenza prevention (knowledge about influenza vaccination efficacy, que to action in vaccinee, perceptible benefit, barrier to vaccination). Results : 309 completed questionnaires from HCWs were returned. Mean age and mean duration of work in hospital were higher and longer among vaccinee than non-vaccinee. Even though the necessity of influenza vaccination among HCWs were accepted well in vaccinee compared to nonvaccinee, the accurate reasons for vaccination were not quite understood among HCWs regardless of compliance. Vaccine campaign (30.8%) and advise from doctors (24.7%) were important for the promotion of vaccination among vaccinee. However, major reason for non-compliance among nursing staff and was mis-confidence that their bodies' self defense mechanisms would ward off infection (33.5%) and 'too busy to get injection' for doctors (65%). Conclusion : We conclude that regular education about perceptible benefits and wrong concerns about influenza vaccination among HCW's and easy accessibility to vaccination were important determinants to improve the influenza vaccination. On-site availability of a vaccination-nurse also proved to be important.

      • KCI등재

        만성질환자에서 인풀루엔자 예방 접종의 효능 분석 : 후향적 환자-대조군 연구

        박승철,정희진,손장욱,최선주,엄중식,우흥정,천병철,김우주 대한감염학회 2004 감염과 화학요법 Vol.36 No.4

        목적: 인플루엔자는 예방접종을 통하여 효과적으로 예방이 가능한 대표적인 호흡기 감염질환이다. 미국이나 국내의 인플루엔자 예방접종 지침에서 고령인구(50세 또는 65세 이상)와 그 외의 만성질환자들을 인플루엔자 예방접종의 일차 대상자로 정하고 있다. 그러나 국내에서는 아직까지 만성질환자들에서의 인플루엔자 백신의 효능평가에 대한 연구결과가 없는 실정이며 국내에서의 만성질환의 분포가 외국의 그것과 일치하지 않기 때문에 본 연구에서는 국내 만성질환자들에서 인플루엔자 예방접종과 연관된 병원입원율의 차이를 비교해 보고자 하였다. 재료 및 방법 : 1999년 11월-2000년 3월(5개월간) 서울 소재 2개 대학병원에 입원한 만성질환자중 발열과 호흡기 증상이 있어 인플루엔자 또는 인플루엔자양 질환이 의심되거나 그로인한 만성질환의 악화로 추정되는 환자군과 이를 배제한 대조군을 중심으로 혈중 인플루엔자 항체가를 조사하였고 인플루엔자 백신접종력을 조사하였다. 결과의 해석은 로지스틱 회귀분석을 이용하였다. 결과 : 만성질환자를 대상으로한 환자 대조군 연구에서 2개 대학병원에서 1년간 조사한 결과 항체 검사에 기준하여 최종적으로 환자군 64명, 대조군 117명이 포함되었다. 환자군에서는 대부분이 호흡기질환(253%)과 심혈관계질환(313%)였던 반면에 대조군은 암(466%)이 가장 많았고 심혈관계질환과 호흡기계질환은 각각 134%, 60%로 낮았다. 또한 두군간에는 예방접종의 경력에서 통계적으로 유의한 차이를 보였으며 이때의 비차비(OR)은 0328로서 인플루엔자 예방접종의 입원 예방효능은 672%이었다. 결론 : 만성질환자, 특히 만성 심폐질환들에서의 인플루엔자 예방접종은 불필요한 입원을 줄이는 효과가 관찰되었다. 따라서 의료인들은 고위험군의 환자들에 대하여 인플루엔자 에방접종을 적극적으로 권장하고 실천하여야 하겠다. Background : Influenza is one of the preventable respiratory disease by annual vaccination. Elderly people and patients with chronic medical disease are the primary target for influenza vaccination according to ACIP (Advisory Committee on Immunization). This study was done to determine whether influenza vaccination affects hospitalization due to influenza like illness or it's related complications among chronic ill patients. Materials and methods : Retrospective, case-control study was conducted for 5 months (Nov. 1999-Mar. 2000). Physicians from two-university hospitals in Korea were instructed to collect clinical data, sera from subjects presenting with a flu-like illness or flu-related exacerbation in patients with chronic underlying diseases. We compared the vaccination history of case patients with control. Logistic regression analysis was used to calculate the odd ratio and efficacy of influenza vaccination. Results : Hospitalization due to ILI (influenza like illness) or it's related complications were observed more frequently in patients with chronic lung disease (25.3%) and chronic cardiac disease (31.3%) compared to others. Influenza vaccination resulted in fewer hospitalization with ILI or ILI-related acute exacerbation of underlying disease in chronic ill patients (adjusted odd ratio, 0.328 [CI, 0.14 to 0.73]) during influenza seasons. Conclusion : For patients with chronic disease, influenza vaccination is associated with substantial health benefit including fewer hospitalization. Health care providers should take advantage of all opportunities to immunize these high-risk patients.

      • SCOPUSKCI등재

        Transplantation of Muscle-Derived Stem Cells into the Corpus Cavernosum Restores Erectile Function in a Rat Model of Cavernous Nerve Injury

        Woo, Jang Chun,Bae, Woong Jin,Kim, Su Jin,Kim, Sung Dae,Sohn, Dong Wan,Hong, Sung Hoo,Lee, Ji Youl,Hwang, Tae-Kon,Sung, Young Chul,Kim, Sae Woong 대한비뇨기과학회 2011 Investigative and Clinical Urology Vol.52 No.5

        <P><B>Purpose</B></P><P>Muscle-derived stem cells (MDSCs) harvested from skeletal muscles have the advantage of providing easier access and do not pose the immunogenic risks of embryonic stem cells. We investigated the effect of intracavernosal transplantation of MDSCs on erectile function in rats with bilateral cavernous nerve injury.</P><P><B>Materials and Methods</B></P><P>Adult male white rats underwent experimentation in 3 groups: group I, sham operation; group II, bilateral cavernous nerve injury; group III, bilateral cavernous nerve injury with MDSC injection. MDSCs were harvested from the femoral muscle of rats and were then injected into the cavernosum. Survival of MDSCs and measurement of erectile function was studied after 4 weeks. We checked the intracavernosal pressure (ICP) and obtained penile tissue. The expression of cyclic guanosine monophosphate (cGMP) was analyzed.</P><P><B>Results</B></P><P>Four weeks after transplantation, PKH-26-labeled MDSCs were identified in the cavernosal tissues of group III. Peak ICP and the drop rate of group II were 52±8.7 mmHg and 34±6.5 mmHg/min, respectively, whereas peak ICP and the drop rate of group III were 97±15.6 mmHg and 17±4.9 mmHg/min, respectively, showing that erectile function improved after MDSC transplantation (p<0.05). The expression of cGMP was significantly lower in group II (21.9±5.8 fmol/well) than in group I and group III (70.2±10.3 and 58.9±10.5 fmol/well, respectively).</P><P><B>Conclusions</B></P><P>In a cavernous nerve injury rat model, intracavernosal transplantation of MDSCs showed acceptable survival of MDSCs as well as improvement of erectile function.</P>

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