Immediate Vitrectomy for Acute Endophthalmitis in Patients with a Visual Acuity of Hand Motion or Better

Jaemin Kim(Jaemin Kim),Hyoung Seok Kim(Hyoung Seok Kim),Su Jin Yoo(Su Jin Yoo),Moon Jung Choi(Moon Jung Choi),Youngju Lew(Youngju Lew),Jong Woo Kim(Jong Woo Kim),Han Joo Cho(Han Joo Cho) 대한안과학회 2022 Korean Journal of Ophthalmology Vol.36 No.5

Purpose: To determine the efficacy of immediate pars plana vitrectomy as the primary treatment for acute endophthalmitis in patients with a visual acuity (VA) of hand motion (HM) or better. Methods: A total of 149 patients who were referred to a single center for acute endophthalmitis after cataract surgery over the 13-year study period were retrospectively analyzed. Only patients presenting with a VA of at least HM were included. Patients were initially treated with either primary vitrectomy or intravitreal antibiotic injection alone, and their visual outcomes and reintervention rates after initial treatment were compared. Results: There was no significant difference in the proportion of good (final VA ≥20 / 40) and poor (VA ≤ counting finger) visual outcomes between the groups. However, subgroup analysis of patients with a VA of HM (92 eyes) showed that the incidence of reintervention (14 of 72 eyes [19.4%] vs. 9 of 20 eyes [45.0%]) and poor visual outcomes (10 of 72 eyes [13.9%] vs. 8 of 20 eyes [40.0%]) were lower after prompt vitrectomy than after intravitreal antibiotic injection alone (p = 0.019 and p = 0.022, respectively). For those with a VA of at least counting finger, no significant difference was observed between the groups. Conclusions: For patients with endophthalmitis presenting with a VA of HM, performing a prompt vitrectomy reduced the incidence of reintervention and poor visual outcomes than the administration of intravitreal antibiotics alone. Our results suggest that primary vitrectomy for patients with endophthalmitis presenting with a VA of HM could be more beneficial than intravitreal antibiotic injection alone.

Characterization of the Lsi1 Homologs in Cucurbita moschata and C. ficifolia for Breeding of Stock Cultivars Used for Bloomless Cucumber Production

Jaemin Jung,Joonyup Kim,Bingkui Jin,Youngmi Choi,Chang Oh Hong,Hyun Ho Lee,Youngwhan Choi,Jumsoon Kang,Younghoon Park 한국원예학회 2017 원예과학기술지 Vol.35 No.3

Bloomless cucumber fruits are commercially produced by grafting onto the pumpkin stocks (Cucurbita moschata ) to restricted silicon (SiO₂) absorption. Inhibition of silicon absorption in bloomless stocks is conferred by a mutant allele of the CmLsi1 homologous to Lsi1 in rice. In this study, we characterized the Lsi1 homologs in pumpkin (C. moschata ) and its coldtolerant wild relative C. ficifolia (‘Heukjong’) in order to develop a DNA marker for selecting a bloomless trait and to establish the molecular basis for breeding bloomless stock cultivars of C. ficifolia . A Cleaved amplified polymorphic sequence (CAPS) marker (CM1-CAPS) was designed based on a non-sysnonymous single nucleotide polymorphism (SNP, C>T) of the CmLsi1 mutant-type allele, and its applicability for Marker-assisted selection (MAS) was confirmed by evaluating three bloom and five bloomless pumpkin stock cultivars. Quantitative RT-PCR of the CmLsi1 for these stock cultivers implied that expression level of the CmLsi1 gene does not appear to be associated with the bloom/bloomless trait and may differ depending on plant species and tissues. A full length cDNA of the Lsi1 homolog [named CfLsi1 (B⁺)] of ‘Heukjong’ (C. ficifolia ), was cloned and sequence comparison between CmLsi1 (B⁺) and CfLsi1 (B⁺) revealed that there exists total 24 SNPs, of which three were non-synonymous. Phylogenetic analysis of CfLsi1 (B⁺) and Lsi1 homologs further revealed that CfLsi1 (B⁺) is closesly related to Nodulin 26-like intrinsic proteins (NIPs) and most similar to CpNIP1 of C. pepo than C. moschata.

Design of Portal System for Supercomputing Services

Jaemin Choi,Sangho Lee,Sungjun Kim,Joon Woo 중소기업융합학회 2015 중소기업융합학회 국제학술대회논문집 Vol.2 No.1

Supercomputing resources are used to the technology research and product development in several areas. Demand of supercomputing resources is increasing continuously. Although we build a world-class supercomputing infrastructure, researchers have difficulty in using a supercomputer. To solve these difficulties, a systematic training of supercomputers and supercomputing service environment is required. In this paper, we design an application-based portal system for supercomputing service environment. Researchers can easily and conveniently use the supercomputing resources through the portal system.

Association of Microbial Dysbiosis with Gallbladder Diseases Identified by Bile Microbiome Profiling

Choi Seong Ji,Kim Yeseul,Jeon Jehyun,Gwak Ho-Jin,Kim Mimi,Kang Kyojin,Kim Yohan,Jeong Jaemin,Jung Yun Kyung,Lee Kyeong Geun,Choi Ho Soon,Jung Dong-Hwan,Lee Sung-Gyu,Lee Yangsoon,Shin Su-Jin,Jang Kiseo 대한의학회 2021 Journal of Korean medical science Vol.36 No.28

Background: Cholecystitis is an important risk factor for gallbladder cancer, but the bile microbiome and its association with gallbladder disease has not been investigated fully. We aimed to analyze the bile microbiome in normal conditions, chronic cholecystitis, and gallbladder cancer, and to identify candidate bacteria that play an important role in gallbladder carcinogenesis. Methods: We performed metagenome sequencing on bile samples of 10 healthy individuals, 10 patients with chronic cholecystitis, and 5 patients with gallbladder cancer, and compared the clinical, radiological, and pathological characteristics of the participants. Results: No significant bacterial signal was identified in the normal bile. The predominant dysbiotic bacteria in both chronic cholecystitis and gallbladder cancer were those belonging to the Enterobacteriaceae family. Klebsiella increased significantly in the order of normal, chronic cholecystitis, and gallbladder cancer. Patients with chronic cholecystitis and dysbiotic microbiome patterns had larger gallstones and showed marked epithelial atypia, which are considered as precancerous conditions. Conclusion: We investigated the bile microbiome in normal, chronic cholecystitis, and gallbladder cancer. We suggest possible roles of Enterobacteriaceae, including Klebsiella, in gallbladder carcinogenesis. Our findings reveal a possible link between a dysbiotic bile microbiome and the development of chronic calculous cholecystitis and gallbladder cancer.

Current concepts of Neurofibromatosis Type 1: Pathophysiology and Treatment

Jaemin Choi,Sungbin An,So Young Lim 대한두개안면성형외과학회 2022 Archives of Craniofacial Surgery Vol.23 No.1

Neurofibromatosis type 1 is the most common tumor predisposition syndrome inherited in an autosomal dominant (100% penetrance) fashion with a wide variety of expressivity. From the perspective of plastic surgery, the most significant clinical symptoms, including disfiguration, peripheral neurologic symptoms, and skeletal abnormalities, are caused by various tumors originating from the affected nerves. Surgical removal is the standard of care for these tumors. However, the outcome is frequently unsatisfactory, facilitating the search for additionaltherapeutic adjuvants. Current trials of molecularly targeted therapies are promising.

아스팔트용 고강도 앵커시스템의 인발강도식 검토에 관한 기초적 연구

Jaemin Choi,Seungyong Lee,Kitae Sung,Youngdoo Han 한국재난정보학회 2017 한국재난정보학회 논문집 Vol.13 No.3

인장하중을 받는 아스팔트 도로용 고강도 앵커의 강도특성에 관한 기초 성능을 규명하기 위해 앵커 매립깊이, 포장두께, 앵커 직경, 앵커 종류, 실험 온도, 에폭시 종류, 그룹인발 수량 등을 실험변수로 하여 정적 인발실험을 실시하고, 아스팔트 앵커의 인발강도에 대하여 분석을 실시하였다. 그 결과 아스팔트 앵커의 강재강도는 기존 콘크리트 앵커의 강재강도식을 적용하면 1.08배 이상의 안전율을 확보할 수 있으므로 콘크리트 앵커 강재강도식을 사용하여도 무관한 것으로 나타났다. 아스팔트 앵커의 실험을 통해 얻은 인발하중을 제안식과 비교하면 약 ±10% 이내의 오차로 근사치를 나타내고 있다. 이로부터 아스팔트 앵커의 경우에도 콘크리트 앵커와 동일한 투영면적의 비가 성립될 수 있을 것으로 판단된다. In order to investigate the basic performance of the high strength anchor for asphalt road subjected to tensile load, the static pullout test was carried out and the pullout strength of the asphalt anchor was analyzed. In the pullout test, the depth of anchor, depth of pavement, diameter of anchor, type of anchor, experimental temperature, epoxy type and amount of anchor were used as test variables. As a result, the steel strength of asphalt anchor was 1.08 times higher than that of conventional anchor concrete, therefore it is considered appropriate to use the steel strength formula of concrete anchor for asphalt anchor. Compared with the proposed formula, the pullout load obtained from the test of the asphalt anchor was within ± 10%. The ratio of the projected area of the asphalt anchor is the similar as that of the concrete anchor.

Autogenous fat grafting for mild-to-moderate postoperative temporal hollowing after decompressive craniectomy: One-year follow-up

Jaemin Choi,신동혁,최현곤 대한성형외과학회 2018 Archives of Plastic Surgery Vol.45 No.1

Background Temporal hollowing is inevitable after decompressive craniectomy. This complication affects self-perception and quality of life, and various techniques and materials have therefore been used to restore patients’ confidence. Autologous fat grafting in postoperative scar tissue has been considered challenging because of the hostile tissue environment. However, in this study, we demonstrate that autologous fat grafting can be a simple and safe treatment of choice, even for postoperative depressed temporal scar tissue. Methods Autologous fat grafting was performed in 13 patients from 2011 to 2016. Fat was harvested according to Coleman’s strategy, using a tumescent technique. Patient-reported outcomes were collected preoperatively and at 1-month and 1-year follow-ups. Photographs were taken at each visit. Results The thighs were the donor site in all cases for the first procedure. The median final volume of harvested fat was 29.4 mL (interquartile range [IQR], 24.0–32.8 mL). The median final volume of fat transferred into the temporal area was 4.9 mL on the right side (IQR, 2.5– 7.1 mL) and 4.6 mL on the left side (IQR, 3.7–5.9 mL). There were no major complications. The patient-reported outcomes showed significantly improved self-perceptions at 1 month and at 1 year. Conclusions Despite concerns about the survival of grafted fat in scar tissue, we advise autologous fat grafting for patients with temporal hollowing resulting from a previous craniectomy.

Hamlet`s (Un)manly Grief: the Cult of the Past in the Age of Theatrical Power

( Jaemin Choi ) 한국영미문화학회 2017 영미문화 Vol.17 No.1

The mourning and grief practice richly registered in Shakespeare`s Hamlet is one of the abiding themes that critics have been fascinated with. This paper attempts to take a fresh look at the issue by building its arguments on Benjamin`s insight that the modern art (mechanically) reproducing the exhibition value brings about the destruction of the ritual value and favors the conditions of melancholy. Instead of taking for granted that Hamlet`s performance of grief is fundamentally different from those of other characters such as Gertrude, Ophelia, and Laertes, this paper argues that Hamlet`s performance comes to be recognized masculine and different from others, only because he presents himself to be so through his theatrical performance as well as his princely power that the subjects (others in the story) ought to ascribe to. To prove this point, this paper closely analyzes Hamlet`s rhetorics and the ways he constructs his mourning self, which is emblematic of the shift in art history that Benjamin has characterized with the terms of "ritual value" and "exhibition value." In conclusion, this paper suggests that Shakespeare`s Hamlet marks the change of the historical horizon, a permanent removal from the past in which the ritual value had been once protected, pushing us to a new age to live with melancholy and the disconnection from things and their muted language.

THE SEX POLITICS OF APHRA BEHN’S THE ROVER

Jaemin Choi(최재민) 미래영어영문학회 2022 미래영어영문학회 학술대회 자료집 Vol.2022 No.6

아스팔트용 고강도 앵커시스템의 인발강도식 검토에 관한 기초적 연구

Choi, Jaemin,Lee, Seungyong,Sung, Kitae,Han, Youngdoo 한국재난정보학회 2017 한국재난정보학회 논문집 Vol.13 No.3

인장하중을 받는 아스팔트 도로용 고강도 앵커의 강도특성에 관한 기초 성능을 규명하기 위해 앵커 매립깊이, 포장두께, 앵커 직경, 앵커 종류, 실험 온도, 에폭시 종류, 그룹인발 수량 등을 실험변수로 하여 정적 인발실험을 실시하고, 아스팔트 앵커의 인발강도에 대하여 분석을 실시하였다. 그 결과 아스팔트 앵커의 강재강도는 기존 콘크리트 앵커의 강재강도식을 적용하면 1.08배 이상의 안전율을 확보할 수 있으므로 콘크리트 앵커 강재강도식을 사용하여도 무관한 것으로 나타났다. 아스팔트 앵커의 실험을 통해 얻은 인발하중을 제안식과 비교하면 약 ${\pm}10%$ 이내의 오차로 근사치를 나타내고 있다. 이로부터 아스팔트 앵커의 경우에도 콘크리트 앵커와 동일한 투영면적의 비가 성립될 수 있을 것으로 판단된다. In order to investigate the basic performance of the high strength anchor for asphalt road subjected to tensile load, the static pullout test was carried out and the pullout strength of the asphalt anchor was analyzed. In the pullout test, the depth of anchor, depth of pavement, diameter of anchor, type of anchor, experimental temperature, epoxy type and amount of anchor were used as test variables. As a result, the steel strength of asphalt anchor was 1.08 times higher than that of conventional concrete anchor, therefore it is considered appropriate to use the steel strength formula of concrete anchor for asphalt anchor. Compared with the proposed formula, the pullout load obtained from the test of the asphalt anchor was within ${\pm}10%$. The ratio of the projected area of the asphalt anchor is similar as that of the concrete anchor.