정상 한국인에서 연령증가에 따른 혈장 Dehydroepiandrosteronesulfate ( DHEA-S ) 농도 및 DHEA - S / cortisol 비의 변화

박성우,유형준,임성희,최문기,유재명,박민숙,이권엽,박철수,김철홍,김현규,김두만,박규용 대한내분비학회 1997 Endocrinology and metabolism Vol.12 No.2

Backgroud: DHEA-S is the most abundant steroid hormone in circulation, and primarily secreted from the adrenal cortex, but its physiological role is little known. One of the characteristic features of DHEA-S is progressive decrement of plasma DHEA-S level with advancing age, in contrast, plasma levels of other adrenal hormones are not chaging or littie decreasing. To grasp the trends of plasma DHEA-S level and DHEA-S/cortisol ratio by age in healthy Korean, we measured the plasma DHEA-S levels and DHEA-S/cortisol ratios in healthy Korean. Methods: Healthy Korean(men: 99, women: 102, age range: 15-97 year old)were studied. Subjects were not taking drugs(such as glucocorticoid or androgenic medication) or cigarettes known to modify the plasma level of DHEA-S and cortisol, and had no evidence of hepatic, renal disease or hyperlipidemia as determined by serum lipid, bilirubin, SGOT, SGPT, BUN, creatinine. Data were analyzed by 10-year age group for men and women: i.e, 10-19, 20-29, 30-39, 40- 49, 50-59, 60-69, 70-79, 80-89 and 90 year or more. Plasma DHEA-S levels were measured by using a commercially available RIA kit with 125I labeled-DHEA-SO4(Coat-A Count DHEA-SO4), and for the measurement of plasma cortisol levels, commercial Gamma Coat TM[125I] Cortisol Radioimmunassay Kit was used. Results:. 1) In both men and women, plasma DHEA-S level showed high interindividual variation within the same age group. 2) There were individual sex differences in plasma levels of DHEA-S, in all age groups, plasma DHEA-S levels were significantly higher values for men than for women. 3) Maximum plasma DHEA-S levels(men; 237+-3.35 ug/dL, women; 108+-17.5 ug/dL) were at third decade in both men and women. 4) Both men and women showed the continuous decline in plasma DHEA-S level with age. These age-related decline was more prominent in men than in women(men; y= -3.152 * +292.6, r2= 0.8459, P$lt;0.05, women; y= -1.417 * +143.3, r2 = 0.7278, P$lt; 0.05). 5) As an index of aging, there was no stastical difference between DHEA-S and DHEA- S/cortisol ratio. Conclusion: In healthy Korean, there were high interindividual variation of plasrna DHEA-S levels. In both men and women plasma DHEA-S level was peak at third decade, and from when it declined progressively with age. These results suggest that although the reliability of single plasma DHEA-S measurement are limited, the decline of DHEA-S with advancing age might be a specific marker of endocrinologic hormonal milieu(aging index). Also, concerning to individual adrenal secreting capacity, we measured DHEA-S/cortisol ratio. But we did not found that plasma DHEA-S/cortisol ratio is superior to the plasma DHEA-S level as an aging index. (J Kor Soc Endocrinol 12:245-254, 1997)

The Tragedy of Pudd’nhead Wilson에서 정체성의 문제

이재만 ( Lee¸ Jae-man ) 현대영미어문학회 1998 현대영미어문학 Vol.16 No.2

This novel is the story of a young man’s mistaken identity. He thinks he is white, but is in reality colored, and he is heir to wealth without knowing his claim is false. He lives as a free man, but is legally a slave. When he learns ― a true fact about himself, he comes to ruin not through the knowledge of his physical status, but through the weakness belonging to both races. The psychological twins in this novel are switched identities, mistaken identities, and foils. Thomas a Becket Driscoll and Chambre de Valet are switched identities, and so they are naturally mistaken ones at the same time. David Wilson and Roxy are mistaken identities and they also become foils to each other. In fact, the false Tom is a foil to David Wilson, not to Chambers. Like this, the major characters of the novel are interrelated with each other. The fictional and conventional injurious effects of the slavery which represented largely centering around the life and consciousness of Roxy, Tom and Chambers falls to the white masters as well as the negro slaves. The slaves lead a forced and implanted lives instead of their own, which results in the loss of their self-interest and even self-identity amid the mire of fictious institutional fetters. The Psychological twins’ effort of trying to discover their true identities all come to end in a nightmare. Such result is specially notable in Mark Twain’s later novels through his deepening pessimism in his later years. His conclusion may be that man’s true identity cannot be found and held up in the social situation of “damned human race” in which there prevail the acquisitiveness of the Gilded Age, race prejudice, hypocritical view of religion, man’s cruelty with each other, neo-aristocracy, and miscegenation.

The Tragedy of Pudd’nhead Wilson에서 정체성의 문제

이재만 현대영미어문학회 1999 현대영미어문학 Vol.16 No.2

This novel is the story of a young man's mistaken identity. He thinks he is white, but is in reality colored, and he is heir to wealth without knowing his claim is false. He lives as a free man, but is legally a slave. When he learns - a true fact about himself, he comes to ruin not through the knowledge of his physical status, but through the weakness belonging to both races. The psychological twins in this novel are switched identities, mistaken identities, and foils. Thomas a Becket Driscoll and Chambre de Valet are switched identities, and so they are naturally mistaken ones at the same time. David Wilson and Roxy are mistaken identities and they also become foils to each other. In fact, the false Tom is a foil to David Wilson, not to Chambers. Like this, the major characters of the novel are interrelated with each other. The fictional and conventional injurious effects of the slavery which represented largely centering around the life and consciousness of Roxy, Tom and Chambers falls to the white masters as well as the negro slaves. The slaves lead a forced and implanted lives instead of their own, which results in the loss of their self-interest and even self-identity amid the mire of fictious institutional fetters. The Psychological twins' effort of trying to discover their true identities all come to end in a nightmare. Such result is specially notable in Mark Twain's later novels through his deepening pessimism in his later years. His conclusion may be that man's true identity cannot be found and held up in the social situation of "damned human race" in which there prevail the acquisitiveness of the Gilded Age, race prejudice, hypocritical view of religion, man's cruelty with each other, neo-aristocracy, and miscegenation.

Incisional Hernia in Adult Liver Transplant Recipients

( Ji Soo Lee ),( Kyeong Sik Kim ),( Chan Woo Cho ),( Kyo Won Lee ),( Gyu-seoung Choi ),( Jong Man Kim ),( Choon Hyuck David Kwon ),( Jae-won Joh ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

Aims: Incisional hernia is one of the complication following abdominal operation. Patients undergoing liver transplantation have a high risk of developing an incisional hernia because of immunosuppression. The purpose of this study is to review incisional hernia cases after liver transplantation and to identify the risk factors for hernia formation. Methods: We retrospectively reviewed and analyzed the medical records of the ninety-four incisional hernia patients after liver transplant recipients from January 2000 to December 2015 in single center institution. Results: 1463 underwent adult liver transplantation during the study period. 94 Incisional hernia patients were found among them. The overall incisional hernia rate was 6.4 %. Mean age was 54 years old and 76.6 % were men. No significant difference was observed for sex, diagnosis, smoking, alcohol, albumin, Child-Pugh score, MELD score, intensive care unit stay, hepatorenal syndrome, ventilator, spontaneous bacterial peritonitis, diabetes, bile leakage, wound problems between patients with incisional hernia and patients without incisional hernia. The characteristics of patients with incisional hernia showed old recipient, more body weight, higher body mass index, living donor recipient compared with patients without incisional hernia. Hypertension, tuberculosis, rejection, postoperative complication event before hernia were significant risk factor (p<0.05). Conclusions: Present study identifies the risk factors for incisional hernia. Surgeons should strive to reduce the risk of incisional hernia after adult liver transplantation.

누에의 軟化病에 關한 硏究 : Ⅰ. Identification and pathogenicity of etiologic agent 제1보 原因菌의 分離同定과 病原性에 對하여

李載窪,趙成萬 全南大學校 農漁村開發硏究所 1978 農業科學技術硏究 Vol.13 No.-

軟化病蠶에서 分離된 菌의 生物化學的 性狀과 누에에 대한 病原性試驗結果를 要約하면 다음과 같다. 1. 分離菌의 形態, 培養性狀 및 生物化學的 性狀檢査 結果 Bacillus thringiensis의 性狀과 大體로 一致하였다. 2. 分離菌은 病原性이 確認되었으며 特히 培養菌의 生理的 食鹽水浮遊液添食區가 斃死率이 가장 높았고 分離菌의 斃死까지의 期間은 齡이 增加할수록 길어졌으며 斃死率은 4, 3, 5齡 順으로 높은 것으로 觀察되었다. The biochsmical characteristics of the isolated bacteria from silkworms infected with Flacherie and its pathogenicity were examined. The results obtained were summarized as follows: 1. The biochemical characteristics of isolated bacteria were almost similar to the characteristics of Bacillus thuringiensis. 2. The pathgenicity of the isolated bacteria was recognized and the ratio of dead to alive number of silkworms was remarkably highest in the mulberry leaves fed with saline-suspension. The incubation-psriod of pathogenic agent was highly extended with the instar advanced and the ratio of dead to alive number of silkworms was higher in the order of 4th instar>3rd>5th.

현장계측용 변위계의 환경영향 특성연구

이한준,최만용,박정학,임재학 한국공작기계학회 2004 한국공작기계학회 추계학술대회논문집 Vol.2004 No.-

The sensor and measuring instrument that are used for the infrastructure is discussed the reliability problem from the various environment factors. In the domestic infrastructure, the low reliability products are produced, because of lack of the pertinent test methods and equipments. To improve the practical use and accuracy of the sensor, it raises the measurement reliability about the sensor and measurement instrument. In this study, the variance of the displacement value according to temperature was investigated using the LVDT for the infrastructure. The experimental results showed that a sensor is affected by environment factor such as temperature.

좌측흉수로 발현된 Boerhaave 증후군 1예

이준,변유미,조민근,조주연,원경준,김영대,박찬국,김만우,유재근,서홍주,이석기 朝鮮大學校 附設 醫學硏究所 2008 The Medical Journal of Chosun University Vol.33 No.2

구토 후 발생한 토혈을 주소로 내원한 환자에서 좌측 늑막 삼출 동반 시 식도 파열의 가능성을 고려하여 흉수 천자 및 지속적인 흉부 단순 촬영의 추적관찰이 필요하며 식도 파열이 배제된 후 환자의 생체 징후 및 토혈 양을 파악하여 내시경 검사 시기를 신중히 결정하는 것이 좋을 것으로 생각된다. 본 증례는 토혈을 주소로 내원하여 Mallory-Weiss 증후군 의심 하에 내시경을 통한 치료 시행 후 추적 관찰에 의해 진단된 Boerhaave 증후군을 경험하였기에 보고하는 바이다. Boerhaave's syndrome is a spontaneous perforation of the esophagus most commonly resulting from a sudden increase in intraesophageal pressure combined with negative intrathoracic pressure caused by straining or vomiting. Surgery should generally be performed within 24 hours because mortality approached 30 to 50 percent in which surgery was delayed. Therefore, early diagnosis and prompt surgical repair are critical for survival. We have experienced a case of Boerhaave's syndrome in a patient presenting with hematemesis with left pleural effusion without any signs or symptoms of pneumomediastinum or pneumothorax.

데이터 品質 管理 方案 硏究

이재범,한만호 서강대학교 경영학연구원 2004 서강경영논총 Vol.15 No.1

저품질의 데이터는 잘못된 의사결정을 초래하여 중요한 사업 기회를 놓쳐버리게 하거나 때로는 기업의 존폐 문제에 까지 영향을 미칠 수 있다. 대부분의 기업들은 데이터 품질 향상을 위한 전문 담당자를 배치하지 않고 있으며 신시스템 구축이나 데이터웨어하우스(DW), 고객관계관리(CRM) 구축 시 일시적인 데이터 정제(Data cleansing)를 실시하는 정도에 그치고 있으며, 데이터 품질의 중요성을 인지한 기업이라도 데이터 저품질로 인한 사업기회의 상실과 경제적인 손실이 가시적으로 당장 사업에 타격을 주는 것이 아니기 때문에 데이터 품질 관리에의 투자를 마지막 순위에 두는 경향이 있다. 본 연구는 먼저 데이터 품질 관리에 대한 정의를 정확히 하고 이를 기반으로 하여 국내 데이터 품질 관리의 실태를 파악한 후에 데이터 품질관리의 요소를 크게 데이터 품질 평가, 데이터 품질 관리 방법론, 데이터 품질관리 통제로 나누어 체계적인 데이터 품질 관리 방안을 연구하도록 한다.

資源貧弱性과 韓國經濟에 관한 硏究

李載萬 圓光大學校大學院 1989 論文集 Vol.4 No.-

Natural Resources Could refor to all the living and nonliving endowment fo the earth. Also, Natural Resoures is a prerequisite for Economic Growth in Countries. But, Traditionally, Our Country in Very poor in the resources. and so, We have to import the scarce in resources from abroad. Comsequently, in this, the general state of things a study on Resources and Economic Growth that could be an abstacle factor in korean Economic Development. Also, I think the subject demands colse further investigation. The structure of this thesis consists in five chapters, chapter I introduce the aim, method and scope of this study, chapter Ⅱ considered the Resources and Wconomic Growth. chapter Ⅲ deals with the resource supply and demand the present condition in korea, and its a prospect. chapter Ⅳ presented the point a issue of resource supply and demand in Korea, and that a direction of the long time Resource Policy. In chapthe Ⅴ, the above mentioned comtents are summarized as a conclusion. In conclusion we should say that the over-all Resource Problem of Korea at present is very serious. but our country is not only in the depths of despair because hold a latent resources and rich in human resource. So, We should grope for possibilities of resource Development, such as, stabilized Security of resouras, Saving for emergency of resources, research of undeveloped resources, diversification of import markets. etc,.

速力槪念의 獲得에 依한 論理的 思考의 形成

李在萬 群山敎育大學 1977 論文集 Vol.11 No.-

J.Piaget exclaimed that the formation of the logical operation of Speed is impossible before the logical thinking period. However, the present study aimed at investigating the mechanism in the development of the recognition of nature, Compared with J. Piaget's genetic estemology. One fundamental hypothese was proposed as follows : When children acquire the conception of speed based on differential velocity, they can answer ever the questions Which, Piaget says, can be solved only by using the logical operation. And also, we employed the instantaneous velooity (in other words, differential velocity) by demonstrating visual display (that will be described later) to the children at the pre-operation stage. The results of a factor analysis led us to confirm that the logical operation of speed was formed. And there appears to be a solid evidence that the children in the experimental group formed the logical operation. It could be seen from an analysis of covarience that the formation of the logical operation increased with the acquisition of the conception of speed.