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Son, Ji Yeon,Kang, Yoon Jong,Kim, Kyeong Seok,Kim, Tae Hyung,Lim, Sung Kwang,Lim, Hyun Jung,Jeong, Tae Cheon,Choi, Dal Woong,Chung, Kyu Hyuck,Lee, Byung Mu,Kim, Hyung Sik Korean Society of ToxicologyKorea Environmental Mu 2014 Toxicological Research Vol.30 No.2
Melamine-induced nephrotoxicity is closely associated with crystal formation in the kidney caused by combined exposure to melamine (Mel) and cyanuric acid (CA). However, there are few dosage-finding studies for toxicological evaluation of chronic co-exposure to Mel and CA. The objective of this study was to investigate the possible mechanism by which a Mel and CA mixture lead to renal toxicity in rats. Mel and CA were co-administered to rats via oral gavage for 50 days. Nephrotoxicity was determined by measuring blood urea nitrogen (BUN) and serum creatinine (sCr) levels. Relative kidney weights were significantly increased in rats after co-exposure to Mel+CA (63/6.3 or 630/6.3 mg/kg) mixtures. BUN and sCr levels were significantly increased after Mel and CA co-exposure. Taken together, significant increase in KIM-1, NGAL, and calbindin levels were observed in the urine of rats exposed to Mel+CA (63/6.3 or 630/6.3 mg/kg) compared with the corresponding control group. Histological analysis revealed epithelial degeneration and necrotic cell death in the proximal tubules of the kidney after co-exposure to Mel+CA (63/6.3 or 630/6.3 mg/kg). Our data suggest that Mel-mediated renal toxicity may be influenced by CA concentrations in Mel-contaminated milk or foods.
( Ji Yeon Son ),( Yoon Jong Kang ),( Kyeong Seok Kim ),( Tae Hyung Kim ),( Sung Kwang Lim ),( Hyun Jung Lim ),( Tae Cheon Jeong ),( Dal Woong Choi ),( Kyu Hyuck Chung ),( Byung Mu Lee ),( Hyung Sik Ki 영남대학교 약품개발연구소 2014 영남대학교 약품개발연구소 연구업적집 Vol.24 No.0
Melamine-induced nephrotoxicity is closely associated with crystal formation in the kidney caused by combined exposure to melamine (Mel) and cyanuric acid (CA). However, there are few dosage-finding studies for toxicological evaluation of chronic co-exposure to Mel and CA. The objective of this study was to investigate the possible mechanism by which a Mel and CA mixture lead to renal toxicity in rats. Mel and CA were co-administered to rats via oral gavage for 50 days. Nephrotoxicity was determined by measuring blood urea nitrogen (BUN) and serum creatinine (sCr) levels. Relative kidney weights were significantly increased in rats after co-exposure to Mel+CA (63/6.3 or 630/6.3 mg/kg) mixtures. BUN and sCr levels were significantly increased after Mel and CA co-exposure. Taken together, significant increase in KIM-1, NGAL, and calbindin levels were observed in the urine of rats exposed to Mel+CA (63/6.3 or 630/6.3 mg/kg) compared with the corresponding control group. Histological analysis revealed epithelial degeneration and necrotic cell death in the proximal tubules of the kidney after co-exposure to Mel+CA (63/6.3 or 630/6.3 mg/kg). Our data suggest that Mel-mediated renal toxicity may be influenced by CA concentrations in Mel-contaminated milk or foods.
Ji Yeon Son,Yoon Jong Kang,Kyeong Seok Kim,Tae Hyung Kim,Sung Kwang Lim,Hyun Jung Lim,Tae Cheon Jeong,Dal Woong Choi,Kyu Hyuck Chung,Byung Mu Lee,Hyung Sik Kim 한국독성학회 2014 Toxicological Research Vol.30 No.2
Melamine-induced nephrotoxicity is closely associated with crystal formation in the kidney caused by combined exposure to melamine (Mel) and cyanuric acid (CA). However, there are few dosage-finding studies for toxicological evaluation of chronic co-exposure to Mel and CA. The objective of this study was to investigate the possible mechanism by which a Mel and CA mixture lead to renal toxicity in rats. Mel and CA were co-administered to rats via oral gavage for 50 days. Nephrotoxicity was determined by measuring blood urea nitrogen (BUN) and serum creatinine (sCr) levels. Relative kidney weights were significantly increased in rats after co-exposure to Mel+CA (63/6.3 or 630/6.3 mg/kg) mixtures. BUN and sCr levels were significantly increased after Mel and CA co-exposure. Taken together, significant increase in KIM-1, NGAL, and calbindin levels were observed in the urine of rats exposed to Mel+CA (63/6.3 or 630/6.3 mg/kg) compared with the corresponding control group. Histological analysis revealed epithelial degeneration and necrotic cell death in the proximal tubules of the kidney after co-exposure to Mel+CA (63/6.3 or 630/6.3 mg/kg). Our data suggest that Mel-mediated renal toxicity may be influenced by CA concentrations in Mel-contaminated milk or foods.
김형동,김종길,오민웅 大韓神經精神醫學會 1984 신경정신의학 Vol.23 No.2
Authors studied the degree of atrophy of alcoholics by measuring ventricle size, cortical sulci size and bifrontal cerebroventricular index. Subjects were consisted of 34 chronic alcoholics and the control group of 25 non-alcoholic neurotics, who were treated at the Department of Neuropsychiatry at Maryknoll Hospital from Mar. 1, 1982 to Aug. 8, 1983. The results were as follows: 1. Cerebral atrophy was found among 24 cases(70.6%) of chronic alcoholics. However, only 1 case of cerebral atrophy was found among the control group. 2. For chronic alcoholics sulci was 6.64±1.48mm, ventricle size was 17.14±2.37mm and the bifrontal cerebroventricular index was 35.6±5.3%, which suggested statistically significant cerebral atrophy, as compared to the control group(p<0.05).
金正善,洪信男,李亨宰,李康熊 한국항공대학교 1991 論文集 Vol.29 No.-
본 연구에서는 방송 송신소에 설치되는 원격제어시스템이 갖추어야 할 기술기준을 제시하였다. 기존의 서비스망을 이용하여 통신을 하는 경우에는 단말장치의 기술기준에 따라야 하고, 무선인 경우에는 전파관리에 관한 법규를 따라야 한다. 대부분의 원격제어시스템이 컴퓨터를 사용하고 있으므로 기능이 다양하고 확장이 용이하다. 원격제어시스템 설치에 대한 규제사항을 최소로 하고, 안전조건과 호환성을 갖기 위한 접속조건을 강조하였다. In this paper, we suggest technical standards for remote control systems to be installed in the broadcasting studios. The remote control systems should follow the technical standards for the terminal equipments when communicating with remote terminals through the dedicated lines or PSTN, and follow the law of radio wave management for radio wave communication. Most remote control systems using the computers have versatile functions and are easy to be expanded. Limitations for the remote control system installation are minimized, and both safety and compatibility are stressed in this work.
김웅비,김 호,박형국,권혁진,김용각 大韓顎顔面成形再建外科學會 1995 Maxillofacial Plastic Reconstructive Surgery Vol.17 No.3
Free grafting of oral mucosa for minor oral reconstruction was first described by Propper in ridge extension surgery. Situation calling for mucosal grafting procedures may relate to periodontal surgery, minor and major preprosthetic surgery, implant surgery, reconstruction in deformity cases after trauma, congenital cleft, gross atrophy and ablative tumor surgery. In the cases of 9 patients with mucosal defect of intraoral or orbital cavity after wide excision of tumor, preprosthetic surgery, and orbitoplasty, full-thickness mucosal graft were used to close a large defect. Four patients received buccal mucosal graft for preprosthetic surgery or orbitoplasty, one patient had benign tumor and the others had malignant tumors located on the palate or upper alveolus. Buccal mucosal graft donor site morbidity and trismus were minimal and healing of surgical defect was satisfactory. So we present the case with review of literatures.
김형락,권세웅,황광선,윤영중 延世大學校 電波通信共同硏究所 2002 電波通信論文誌 Vol.6 No.1
차세대 통신 시스템에서 공통적으로 요구하는 소형화, 광대역화, 집적화추세에 따라 RF소자는 광대역화, 소형화, 집적화를 향해 발전하고 있으며 안테나 기술도 현재 추세에 발맞추어 소형화, 능동집적화, 광대역화를 통하여 개발 방향을 모색하고 있다. 본고에서는 현재 추세인 소형 안테나, 능동 안테나와 더불어 최근 관심이 집중되고 있는 임펄스 통신에 이용될 수 있는 초광대역 안테나 기술에 대해 소개한다. The technical trends of the next generation wireless communication are miniaturization, broad-band operation, and integration. Thus, in accordance with this trend, RF devices and components are being developed in such way, and same with the antenna. In this paper, technology of small antenna, active antenna, and ultra wideband antenna, which can be applied to impulse communication system, are introduced.
김형동,허민,오민웅,김종길 大韓神經精神醫學會 1983 신경정신의학 Vol.22 No.3
The authors experienced a case of mania associated with hyperthyroidism at the Neuropsychiatric Dept. of Maryknoll General Hospital in May, 1982. We observed that this case met the criteria for secondary mania by Krauthammer and Klerman. Manic symptoms disappeared after propylthiouracil and neuroleptic treatment, but amnesia of the manic episode remainded until discharge. We thought that this condition was rare in Korea worth a case report together with an uptodate review of literature.