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Clinical Experience of the Klippel-Trenaunay Syndrome
Sung, Hyung Min,Chung, Ho Yun,Lee, Seok Jong,Lee, Jong Min,Huh, Seung,Lee, Jeong Woo,Choi, Kang Young,Yang, Jung Dug,Cho, Byung Chae Korean Society of Plastic and Reconstructive Surge 2015 Archives of Plastic Surgery Vol.42 No.5
Background The Klippel-Trenaunay syndrome (KTS) is characterized by three clinical features, namely cutaneous capillary malformations, venous malformations, and soft tissue and/or bony hypertrophy of the extremities. The varied manifestations are attributed to the unpredictable clinical nature and prognosis of the syndrome. To elucidate the clinical characteristics of this disease, we reviewed a relatively large number of KTS patients who presented to our vascular anomalies center. Methods We conducted a retrospective study with 19 patients who were diagnosed with KTS and treated in our vascular anomalies clinic between 2003 and 2014, and examined their demographic characteristics, their clinical features, and the treatments administered. Results The sex distribution was balanced, with 9 (47%) males and 10 (53%) females. The mean follow-up period was 4.1 years (range, 7 months-9 years). Most of the patients received conservative treatments such as medication or physiotherapy. Compression therapies such as wearing of elastic garments/bandages were also administered, and surgical interventions were considered only when the patients became excessively symptomatic. Other treatments included laser therapy and sclerotherapy, and all the treatments were adjusted according to each case, tailored to the conditions of the individual patients. Conclusions KTS is an extremely rare, multifactorial disorder that induces widely varied symptoms. Because of this unique feature, plastic surgeons, when not careful, tend to attach a one-sided importance to typical symptoms such as limb hypertrophy or capillary malformation and thus overlook other symptoms and clinical features. KTS can be suspected in all infants who show capillary malformations or limb hypertrophy and require a multi-disciplinary approach for comprehensive management.
Thermosensitive Biodegradable Poly(organophosphazene) Gels and Their Blends
( Sung Bum Jung ),( Gyung Don Kang ),( Jung Yun Huh ),( Sung Sook Ahn ),( Estela C. Monge ),( Gil Son Khang ),( Soo Chang Song ) 한국조직공학과 재생의학회 2006 조직공학과 재생의학 Vol.3 No.2
Thermo-sensitive poly(organophosphazene) hydrogels with hydrophilic α-amino-ω-methoxy-poly(ethyleneglycol) (AMPEG), hydrophobic amino acid esters (L-isoleucine ethyl ester) and glycine lactate ethyl ester as a side group have been synthesized. The poly(organophosphazenes) were characterized by 1H-, 31P-NMR spectroscopies and GPC. The viscosities of the gels were measured by viscometer along with the temperature changes. The poly(organophosphazenes) synthesized form solutions in water at low temperature while they form gels as the temperature increases showing lower critical solution temperature. To control the gelation properties we have studied polymer blends system. We grouped the polymers synthesized in two group such as hard polymers with low Tmax and high Vmax and soft polymers with high Tmax and low Vmax. When these polymers were blended at the appropriate ratio, the blended aqueous solution changed into a transparent hydrogel at the targeted body temperature. According to DSC and IR measurements, the two polymers were blended homogeneously.
Terahertz Reflection-Mode Biological Imaging Based on InP HBT Source and Detector
Yun, Jongwon,Oh, Seung Jae,Song, Kiryong,Yoon, Daekeun,Son, Hye Young,Choi, Yuna,Huh, Yong-Min,Rieh, Jae-Sung IEEE 2017 IEEE transactions on terahertz science and technol Vol.7 No.3
<P>This paper presents the development of an oscillator and a detector based on InP HBT technology operating near 300 GHz, and their application to terahertz reflection-mode imaging. The fabricated fundamental-mode common-base (CB) cross-coupled oscillator exhibits a peak output power of 5.3 dBm at 305.8 GHz, and the CB direct detector shows a responsivity higher than 40 kV/W and noise equivalent power lower than 35 pW/root Hz for a frequency range of 270-345 GHz. The imaging system employing the fabricated circuits as the signal source and detector was characterized for the resolution and dynamic range, and then, successfully applied for imaging various biological samples. The results show that low-power terahertz reflection-mode imaging based on solid-state electronic sources and detectors based on a commercial semiconductor technology is promising for various biomedical imaging applications.</P>