품행장애 청소년의 음악치료 사례연구

권혜경,진혜경 대한소아청소년정신의학회 2000 소아청소년정신의학 Vol.11 No.1

요 약 : 이 사례는 1998년 6월부터 9월까지 주 1회 30분씩 서울국립정신병원에 입원한 품행장애 청소년들을 대상으로 한 음악치료 사례로, 그룹 음악치료에 참여한 환아들 중 가장 지속적으로 참여한 두명의 여자 환아(A, B)에 초점을 맞추었다. 음악치료 세션은 다음과 갈이 3부분으로 나누어진다 ; 시작할 때 부르는 인사노래, 다양한 음악적 활동, 그리고 마칠 때 하는 소리내기와 움직이기 주로 사용되었던 음악치료 기술들로는 자유로운 즉흥연주, 노래 토론, 음악 모노드라마, 그리고 소리내기와 움직이기를 들 수 있다. 자유로운 즉흥연주는 환아들의 감정과 생각을 강화시키고, 동기유발을 하며, 연주를 통해 상징적으로 자신을 볼 수 있게 하기 위해 사용되었다 노래 토론은 그들의 생각을 담아내고 지지하기 위해 사용되었다 음악 모노드라마는 그들이 가지고 있는 대인 관계적 문제에 대한 통찰력을 갖게 하기 위해 사용되었다. 소리내기와 움직이기는 그들에게 결여되어 있는 자발성을 강화하기 위해 사용되었고 이를 통해 자신들의 신체와 목소리를 표현적 도구로 탐색하게끔 만들었다 음악치료를 하는 3개월 동안 환아 A는 그룹에서 대화 기술, 사회성 그리고 행동적인 측면에서 향상을 보였다. 그녀는 음악을 상징적으로 사용할 수 있게 되었고 자신과 자신의 가족에 대한 느낌을 그룹과 공유할 수 있게 되었다. 환아 B는 자기표현 능력이 향상되었다. 그녀는 보다 더 자발적으로 그룹에서 자신의 감정에 대해 말을 할 수 있게 되었다. 비언어적이고 비위협적인 수단으로서 음악은 두 여자 환아들에게 그들이 자신을 표현하기 위해 필요한 신뢰감을 다시 회복할 수 있는 환경을 제공한 것으로 보인다. The short-term music therapy was performed for adolescents with conduct disorder admitted to Seoul National Mental Hospital for 3 months from Jun to September, 1998. This case study focused mainly on two female patients who participated regularly in the group music therapy. The music therapy process wad divided into three phases; beginning, opening up, and closing. This music therapy session consisted of three parts; hello song as beginning, various musical activities, and sound & movement activity as closing. Free musical improvisation, song discussion, musical monodrama, and sound & movement were the mainly applied techniques. Free improvisation was used to enhance, motivate, indentify and contain the adolescents' feelings and ideas. Song discussion was used to convey their thoughts and to support each other. Musical monodrama was used to make them have insights into interpersonal relationships. Sound & movement was used to enhance spontaneity. It made them explore their body and voice as an expressive medium. Throughout three months period of music therapy, patient A's communication skill, socialization, and behavior areas were assessed with improvement. She could use music as a symbolic form and was able to share her feelings about herself and her family. Patient B's self-expression and cognitive areas were assessed with improvement. She became more spontaneous and could verbalize her emotions during the group session. Music as a non-verbal and therefore often a non-threatening medium wherein so much can be expressed provided two female patients an atmosphere where a sense of trust may be regained. KEY WORDS : Music therapy·Conduct disorder·Adolescent.

태아 26예에서 신장단위의 미세구조적 발달

김혜영,주의탁,김경용,이원복 대한해부학회 1995 Anatomy & Cell Biology Vol.28 No.2

여성 관상동맥질환자의 동기요인이 건강행위에 미치는 영향 요인

이혜영,정경옥,김금자 김천과학대학 2007 김천과학대학 논문집 Vol.33 No.-

Background: Misconceptions exist that coronary artery disease(CAD) is a male dominant disease, although the leading cause of death due to heart disease in women increased 7.1% from 2001 to 2004 in Korea. Lack of motivational factors to health behavior change places women at risk for subsequent CAD events. Purpose: The purpose of this study was to investigate motivational factors to health behaviors for women with coronary artery disease. Methods: Structured questionnaires survey was carried out on a convenience sample of 81 adult women in a cammunity setting. The subjects were recruited for an interview at outpatient clinic in hospitals. The data were analyzed using descriptive statistics, Pearson correlation coefficient and stepwise multiple regressions. Results; There were significant correlations between motivational factors and health behaviors(r=.664). Stepwise multiple regression revealed that 57% of variance in health behaviors was explained by self-efficacy and perceived benefits among four motivation variables(F=54.438 p<.01). However, there were no significant predicting factors of perceived barriers and emotional salience among motivational factors to health behaviors. Self-efficacy contributed the greatest amount of variance in health behaviors(β=.585), followed by perceived benefits(β=.226). Conclusions: The results of the study indicate that self-efficacy was very important in predicting health behaviors for women with coronary artery disease. Thus it would be necessary to include motivational factors in designing rehabilitation program to practice and adherence health behaviors for women with coronary artery disease.

한국판-Gilliam 자폐증 평정척도-2(K-GARS-2) 표준화 연구

진혜경,윤혜주,박진박 대한생물치료정신의학회 2011 생물치료정신의학 Vol.17 No.2

Objectives:Autism is one of the most important developmental disorder of childhood, which has been studied in many fields of research. The importance of early detection, diagnosis and early treatment of autism has been emphasized in Korea. However, appropriate diagnostic tools to meet these needs, were insufficient. With increasing number of autistic adults, a need for diagnostic tool which can cover wide range of age has emerged. The Gilliam Autism Rating Scale-2(GARS-2) is based on Autism Society of America and DSM-IV-TR(Diagnostic and Statistical Manual of Mental Disorders-fourth Edition-Text Revision) diagnostic criteria for autism. It is the only available test so far. The target age of this test is from 3 years to 22 years old with autism, therefore this test is thought to be valuable. In this study, Korean-Gilliam Autism Rating Scale-2(K-GARS-2) was standardized, and verified the reliability, validity. Methods:K-GARS-2 was standardized and the reliability, validity was evaluated for 109 patients with autism aged 3 to 22 years. Results:Cronbach’s alpha coefficient of K-GARS-2 is 0.94 in the total 42 items and reliability was verified. KGARS-2 standard scores were highly correlated with scores of CARS and also Items-discrimination coefficients also showed a high correlation. Autism subscale standard score and the Autism quotient also showed a strong correlation. When compared with the other mental disorder groups, autism group show significantly higher scores. Conclusion:With the increasing prevalence of autism, the importance of accurate diagnosis and therapeutic approach is increasing in Korea. In this perspective, K-GARS-2 standardization process is very meaningful.

지역별 보건소 이용의 만족도에 관한 연구 : 경북지역을 중심으로

이혜영,정경옥,김금자 김천과학대학 2007 김천과학대학 논문집 Vol.33 No.-

Purpose: The purpose of this study was to investigate the satisfaction and utilization and awareness of health center and satisfaction's affecting factors. Methods: The subjects consisted of 292 adult at three health centers on middle size cities in Gyeong San Buk-Do. Data was collected from August 2006 to June 2007 using structured questionnaires. One-way ANOVA were used to test satisfaction of health centers, utilization and awareness of health center and Kruskal-Wallis and Scheffe's test were used to test recommendation of health center and Post Hoc multiple comparison by using SPSS 14.0 for windows. Results: The satisfaction of health centers for community dwellers was related to age, educational level and family income and the difference of satisfaction of health centers were in comfortable surroundings, satisfaction of facilities, generosity of staff members and full explanation. The utilization and awareness of health center were differ from community areas. Conclusions: Further studies need to be done to investigate additional effects of satisfaction of health centers for community dwellers and to investigate nursing approaches for community dwellers to improve their satisfaction of health centers.

정상 노인과 치매 환자간 임상화학적 검사 수치의 비교

조경혜,손혜연 THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCIEN 1997 Journal of biomedical laboratory sciences Vol.3 No.2

나이가 들어가면서 나타나는 여러 가지 변화를 임상적으로 검사하고 측정하므로써 건강상태를 예측하는 것은 노화를 지연시키고 건강한 삶을 유지하는데 상당히 유용하고 기초적인 지표가 될 것이다. 점차 증가일로에 있는 노인성 질환의 여러 문제점을 해결하기 위해 노령인구 집단을 정상군과 치매군으로 구분하여 13종의 임상 화학 검사를 시행한 결과, 두 집단 사이에서, 임상 생화학적 검사의 양상의 다를 것이라는 예측대로의 결과를 얻을 수 있었다. 즉, serum albumin, APase, glucose, GOT, LDH 등의 수치는 정상군과 치매군 사이에서 현저한 차이를 보이는 반면, bilirubin, BUN, cholesterol, creatinine, total protein 등의 검사 수치에서는 별다른 차이를 볼 수 없었으며, 그 밖에 calcium, GPT, Pi 검사 등의 결과에서도 두 집단 사이에서 차이를 보였다. 이것은 치매가 체내에서 많은 생화학적 변화를 일으킴을 시사하고, 치매 발병에 여러 가지 환경 요인이 영향을 미치게될 것이라는 결론을 유도할 수 있게 한다. The measurement of many biochemical changes that could be appeared as aging will be resulted in the very useful and basal marker to maintain healthy life and to predict the health condition and the retardation of the aging. We classified the geriatrics into the normal and same aged dementia on the based of clinical diagnostic as well as MMSE evaluation. And then we were collected blood samples from both groups and examined 13 biochemical assays to screen any valuable biochemical index for dementia. Among 13 assays, several assay data showed the statistically significant differences between two groups. The values of serum albumin, APase, and GOT were significantly decreased in demented group compared to control. On the other hand, the values of glucose and LDH were increased in dementia compared to control. Additionally, the value of Pi was increased but the values of calcium and GPT were decreased, without significant difference (p>0.05). The values of other assays such as bilirubin, BUN, cholesterol, creatinine and total protein did not show any statistically significant differences. Conclusively it may be suggested that dementia might be resulted in the variable biochemical changes which could be affected by many environmental factors as well as dementia itself.

여성장애인의 차별실태 및 차별해소에 관한 연구

오혜경 가톨릭대학교 사회복지연구소 2006 사회복지리뷰 Vol.11 No.-

2005년 장애인실태조사 결과, 장애인구는 2,149천명, 재가장애인은 2,101천명으로 추정되며 이중 여성장애인은 약 843천명으로 전체의 40.1%를 차지하고 있으나 더욱 확대될 것으로 전망되고 있다. 여성장애인에 대한 정책적·임상적 접근은 여성주의적 관점을 통한 성평등의 보장과 인간의 삶의 질 향상에 초점을 두는 보편주의적·인간주의적 관점에 기초한 사회통합을 전제로, 통합적으로 조명되어야 하므로 여성장애인에 대한 이중차별구조를 밝히는 단편적 접근으로부터 삶의 질을 향상하고 구체적인 복지 증진을 위한 포괄적·통합적·체계적 접근으로 이동할 필요성이 제기되고 있다. 본 연구에서는 2005년도 장애인실태조사 결과 분석을 통해, 여성장애인의 차별실태 및 복지욕구를 살펴보며 여성장애인의 차별을 해소하기 위한 방안을 제시하고자 한다. 이를 위해 지금까지 여성의 차별을 해소하기 위한 다양한 노력들을 검토하였다. This paper first acknowledges the different social sectors in which disabled women face the most problems, and later, offers substantial solutions for these discriminative problems by examining the situations of double discrimination faced by women with disabilities. In the Korean society, women in general face discrimination against their gender. Women with disabilities, however, not only experience discrimination due to their femininity, but are also the victims of discrimination against their disabilities. As a result, disabled women find themselves having to deal with a double discrimination, which has put an extreme limit on their opportunities in education, marriage, and employment. Disabled people can not be categorized as one population since disabled women, unlike disabled men, face a double discrimination due to their gender. This would mean that women with disabilities not only live inferior lives to the general public, but also live inferior lives in comparison to disabled men. Furthermore, most disabled women are expected to stay at home all day and due to this isolation from society, their quality of life is also, not unexpectedly, very limited. In order to recommend adequate solutions to this problem, it is first necessary to examine, both qualitatively and quantitatively, the real situations of Korean women with disabilities who face a two-fold discrimination aimed against their gender and their physical disabilities. However, living with disabilities is a heavy burden in our lives, as we know well. Especially Korean Disabled women's suffering is doubled because of being both female and disabled. The traditional value and religion-social ideology of Korean society have been a fatal blow in maximizing discrimination against them. Accordingly living as disabled women in Korean society means living with two disabilities such as being both women and disabled. They are biased and severely discriminated in the areas of education, jobs, culture, and religion, etc.

재활상담의 역할과 기능에 관한 연구

오혜경 가톨릭대학교 사회과학연구소 1999 社會科學硏究 Vol.15 No.-

흰쥐의 간에서 Paclitaxel(Taxol)이 방사선에 미치는 효과

이경자,구혜수 梨花女子大學校 醫科大學 醫科學硏究所 1997 EMJ (Ewha medical journal) Vol.20 No.1

연구목적: Paclitaxel은 소관종합체의 형성을 안정화시키는 미소관 dr제제로서 이 작용이 주로 세포주기의 G2-M시기에 일어나기 때문에 방선 감작제의 가능성이 있는 항암제이다. 흰쥐의 간에서 paclitaxel과 방선조사를 병용하여 paclitaxel이 방사선의 효과에 미치는 여향을 파악하기 위한 실험연구이다. 방 법: 흰쥐 52마리를 대상으로 정상대조군, paclitaxel군, 방사선조사군과 paclitaxel과 방사선병용군으로 분류하였다. Paclitaxel군은 paclitaxel(10mg/kg)을 복강내에 1회 주입하였으며, 방사선조사군은 전복부에 8Gy x-ray를 단일 조사하였으며, 병용군은 paclitaxel(10mg/kg)을 주입 후 24시간에 방사선조사(8Gy)를 시행하였다. 실험완료 후 6시간, 24시간, 3일 및 5일에 간의 병리 조직학적 변화를 관찰하였다. 결 과: Paclitaxel군은 유사분열수가 6시간에 증가되어 24시간에 정상으로 회복되었다. 방사선조사군은 조사 후 6시간과 24시간에 apoptosis가 발현하였으며 3일 후 정상으로 회복되었다. 간세포의 괴사는 paclitaxel군, 방사선조사군 및 병용군에서 모두 나타났으며 괴사의 정도는 3군에서 차이가 없었다. 결 론: Paclitaxel주입 후 6시간에 유사분열중지가 유발되었으며 24시간에 정상으로 회복되었고 aoptosis는 발현되지 않았다. 방선조사 후 6시간과 24시간에 apoptosis가 유발되었으며 3일에 정상으로 회복되었다. 간세포의 괴사는 paclitaxel군, 방사선조사군 및 병용군에서 모두 나타났으며 3군에서 정도의 차이ㅏ 없었다. 따라서 paclitaxel을 방사선조사 24시간 전에 주입하여 간세포에서 방사선감작제의 효과는 없었다. Objectives : Paclitaxel(Taxol) si a chemotherapeutic agent with potent microtubule stabilizing activities that arrests cell cycle in G2-M. Since D2-m is the most radiosensitive phase of the cell cycle, paclitaxel has potential as a cell cycle-specific radiosensitizer. This study was designed to investigate the effects of paclitaxel to radiotoxicity in normal rat liver. Materials & Methods : A single intraperitoneal infusion of paclitaxel(10mg/kg), and a single irradiation(8Gy, x-ray) to the whole abdomen, and combination of irradiation(8Gy,x-ray)24 hours after paclitaxel infusion were done in Sprague-Dawley rats. The incidence of mitosis, apoptosis and parenchymal changes of the liver were evaluated at 6 hours, 24 hours, 3 and 5 days, respectively. Results : Paclitaxel and irradiation significantly increased mitosis at 6 hours and apoptosis was increased by irradiation at 6 and 24 hours. Increased numbers of apoptosis at 3 days by paclitaxel alone was not significantly different from control. Combination of paclitaxel and irradiation showed significantly increased numbers of mitosis and apoptosis at 6 hours. The degree of necrosis of hepatocyte was not significantly different between 3 groups. Conclusion : Since the incidence of mitosis, apoptosis and hepatocyte necrosis were not increased by paclitaxel infusion 24 hours before irradiation, paclitaxel did not show radiosensitizing effect in this experimental condition. Studies with conditions similar to clinical situation will be the next stop to define the radiosensitizing effects of paclitaxel.

Nicotine이 계태장기조직의 효소활성에 미치는 영향

조경혜,유은정 서울여자대학교 자연과학연구소 1991 자연과학연구논문집 Vol.2 No.-

임산부 흡연시 담배의 다양한 성분가운데, nicotine이 모체의 대사변동을 통해 간접적으로 또는 태반 융모간 혈류를 따라 직접적으로 태아에게 미치는 영향을 효소학적으로 검증하고자 본 연구를 수행하였다. 인체와의 내성의 차이를 고려하여, 발생중인 계태(8일째)에 0.5ml의 nicotine 용액을 농도별로 (대조군, 제1군:0.206mg/egg, 제2군:0.412mg/egg, 제3군:0.618mg/egg, 제4군:0.824mg/egg) 주입하고, 10일을 더 발육시킨 후 각 장기를 적출하여 마쇄하고 원심분리한 상등액을 시료로 하여 효소활성을 측정한 결과, 대조군에 대한 제2군에서의 specific activity비율이 다음과 같이 증감되었다. Alkaline phosphatase는 폐에서 5.4배, 신장 3.4배, 간과 대퇴부 1.3배, 뇌와 소장에서 1.2배, 심장 1.1배의 증가를 보였고, 위에서는 50% 감소되었다. ATPase는 폐 1.7배, 간 1.6배, 신장에서 1.4배의 증가를 보였고, 심장과 소장에서 1.13배, 위에서 1.07배의 활성을 나타내었으며, 뇌와 대퇴부에서는 오히려 감소하여 각각 90%수준의 specific activity를 보였다. MDH는 152%와 118%로 각각 증가된 폐와 신장을 제외한 모든 장기에서 specific activity가 낮아졌는데, 그 감소비율은 간 29%, 뇌 25%, 위 24% 대퇴부 20%, 심장 17%, 소장 6%로 나타났다. 5'-Nucleotidase는 폐 6.6배, 신장 1.8배, 대퇴부 1.34배, 심장 1.29배, 간 1.1배의 증가를 보인 반면, 뇌와 위, 소장은 대조군에 비해 각각 17%, 22%, 12% 감소를 보였다. Arginase는 폐, 신장에서 각각 1.7배와 1.4배의 두드러진 증가를 보였으며, 뇌와 소장은 1.3배, 간과 대퇴부는 1.1배의 증가가 있었으나, 심장과 위에서는 9%와 19%의 감소를 보여주었다. 소화 및 근육장기에 비해 독성물질을 방어하거나 대사 및 배설하는 장기(간, 폐, 신장)에서 유의적인 증감을 확인할 수 있었는데 특히 폐에서 나타난 큰 변화는 흡연으로 인한 폐조직 손상과는 독립적으로 nicotine이 단독효과를 갖는다는 점을 시사해 준다. 간에서 보다 신장에서의 현저한 효과는 avian species의 대사적 특성으로 말미암아 간기능 일부를 신장이 담당하였기 때문에 나타난 결과로 보며, 이들 enzyme의 활성변화가 사람에게서도 나타나는 가를 확인하기 위해서는 쥐나 원숭이등의 동물실험이 더 부가되어야 하리라 생각된다. In order to study the effect of nicotine on the metabolic activities of the fetal tissues, the changes of enzymatic activities have been investigated in the chick embryonic organs treated with nicotine. Infection concentration which expressed low mortality and ascertained significant change of specific activity is 0.412mg/egg group and each organocellular enzymatic activity is as like follow: 1. Specific activity of alkaline phosphatase is significantly increased in lung, kidney and liver but decreased in stomach. 2. Specific activity of ATPase is increased in lung, liver, and kidney but decreased in brain & thigh muscle. 3. Specific activity of malate dehydrogenase is decreased in liver, brain, stomach, thigh muscle, and heart, but increased in lung and kidney. 4. Specific activity of 5'-nucleotidase is increased in lung, kidney, thigh muscle, and heart but decreased in brain, stomach and intestine. 5. Specific activity of arginase is increased in lung, kidney, brain, and intestine but decreased in heart and stomach. Significant changes of specific activity are ascertained in organs which protect, metabloize or excret toxic materials rather than digestive or muscular organ. In particular, large scale change expressed in lung suggested that the nicotine affccts not only tissue damages by smoking but also the metabolic changes of the fetal tissues at the cellular levels. More remarkable changes in kidney result from metabolic specificity of avian species which kidney is in charge of a part of liver function.