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Han, Yeji,Hwang, JinYoung,Chung, Jun-Young,Yun, Sungdae,Park, HyunWook Wiley Subscription Services, Inc., A Wiley Company 2007 JOURNAL OF MAGNETIC RESONANCE IMAGING Vol.26 No.3
<B>Purpose</B><P>To reduce the artifacts due to pulsatile motion artifacts in diffusion-weighted imaging (DWI) with radial trajectories and to improve the image quality using projection data regeneration.</P><B>Materials and Methods</B><P>The projection data is obtained by a radial spin-echo DWI (rSE-DWI) sequence, from which a temporary image is generated using the inverse Radon transform (IRT). The projection data include some degraded data due to cardiac pulsatile motion. The degraded data are then replaced with data that are regenerated using the Radon transform (RT) of the temporary image. The proposed method for image quality improvement is demonstrated through a computer simulation and in vivo images obtained by rSE-DWI.</P><B>Results</B><P>In general, electrocardiograph (ECG) triggering is used to reduce the degradation of projection data in the DWI with radial trajectories, where the amount of degradation depends on the cardiac phase. Cardiac gating reduces the artifacts resulting from the cardiac pulsatile motion to a certain extent only. The proposed projection data regeneration method successfully improves image quality.</P><B>Conclusion</B><P>The regeneration method based on back-projection reconstruction effectively uses the features of the degraded projections having lower signal intensity than the normal projections, resulting in image quality improvement without acquisition of additional data. J. Magn. Reson. Imaging 2007. © 2007 Wiley-Liss, Inc.</P>
( Yeji Han ),( Hye-kyung Jung ),( Ji Young Chang ),( Chang Mo Moon ),( Seong-eun Kim ),( Ki-nam Shim ),( Sung-ae Jung ),( Joo-young Kim ),( Ji-yun Bae ),( Sae-in Kim ),( Ji-hyun Lee ),( Sanghui Park ) 대한내과학회 2017 The Korean Journal of Internal Medicine Vol.32 No.5
Background/Aims: Duodenitis is not infrequent finding in patient undergoing endoscopy. However, hospitalized patients have a higher incidence of secondary duodenal mucosal lesions that might be related with inflammatory bowel disease (IBD), cytomegalovirus (CMV) infection, tuberculosis, immunologic disorders, or other rare infections. We aimed to identify clinicopathologic features of duodenal mucosal lesions in hospitalized patients. Methods: All hospitalized patients having duodenal mucosal lesions were identi-fied by endoscopic registration data and pathologic data query from 2011 to 2014. The diagnostic index was designed to be sensitive; however, a detailed review of medical record and endoscopic findings was undertaken to improve specificity. Secondary duodenal lesion was defined as having specific reason to explain the duodenal lesion. Results: Among 6,334 hospitalized patients have undergone upper endoscopy, en-doscopic duodenal mucosal lesions was detected in 475 patients. Secondary duo-denal lesions was 21 patients (4.4%) and the most frequent secondary cause was IBD (n = 7). The mean age of secondary group was significantly lower than that in primary group (42.3 ± 18.9 years vs. 58.5 ± 16.8 years, p = 0.00), and nonsteroidal anti-inflammatory drugs were less frequently used in secondary group, but there was no differences of gender or presence of Helicobacter pylori. The involvement of distal part of duodenum including postbulbitis or panduodenitis was more fre-quently detected in secondary group than in primary group. By multivariate re-gression analysis, younger age of 29 years and the disease extent were significant predictors for the secondary mucosal lesions. Conclusions: Secondary duodenal mucosal lesions with different pathophysiol-ogy, such as IBD or CMV infection, are rare. Disease extent and age seems the most distinctive feature of secondary duodenal mucosal lesions.
( Yeji Han ),( Eunmi Nam ),( Kyungeun Lee ),( Youngchul Moon ),( Joomyung Sung ),( Kyungmin Cho ),( Jungeun Choi ),( Jooyoung Kim ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Posterior reversible encephalopathy syndrome (PRES) is known to have symptoms of headache, visual disturbances, altered consciouseness and seizures, which can be result of acute hypertension, eclampsia, renal failure and the use of immunosuppressive or cytotoxic agents. We report a case of PRES ocurred as a result of FOLfiRI (irinotecan, 5-FU) chemotherapy in metastatic colorectal cacer/ Case Report: A 51-year old male with diagnosed of rectal cancer with liver metastasis, underwent an a low anterior resection on April,19, 2013.After operation, he has XELOX (capecitabine, oxaliplatin) as palliative chemotherapy. After sixth XELOX chemotherapy, chemotherapy as change of disease progression. When FOLfiRI chemotherapy administered, suddenly he appeared to have partial seizure with sudden eyeball deviation . The infusion of chemotherapy was stopped immediately ,he had treatment with anticonvulsants, such as phenytoin, levetiracetam. The brain MRI showed that white matter change in the bilateral occipital lobe, supported the diagnosis of PRES. The conservative treatment was continued for several days. After few days, the patient recovered from symptom and after that, he had chemotherapy XELOX and bevacizumab instead of FOLfiRI. The brain MRI after six months did not show any previous lesion, he is currently well being followed up as an outpatient. Conclusion: There are no known reports of the association between PRES and FOLfiRI chemotherapy.We postulate that FOLfiRI chemotherapy can disrupt the normal endothelial function of the brain leading to the development of PRES.