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      • KCI등재후보

        VDT작업별 정신사회적 스트레스와 근골격계 장애에 관한 연구

        백남종,강종두,주영수,배인근,권호장,박종만,조수헌,김돈규,김재용,최홍렬 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.4

        It has been hypothesized that jobs that have both high psychological demands and low decision latitude("job strain") can lead to musculoskeletal disorder. The objective of this study was to test whether job strain was correlated with the presence of work-related musculoskeletal disorder, especially myofascial pain syndrome(MPS). Information on demographic factors, confounders such as household load and taking care of children or not, and scores for decision latitude, job demand, and social support was obtained by self-administered questionnaire, which had been developed in Korean language, by adopting NIOSH instrument and Extended Karasek Model(16 items). All subjects were also examined by rehabilitation medicine specialists for musculoskeletal disorders. Subjects(n=370) could be categorized into 4 groups, these were, housewives(n=89), shipyard CAD workers(n=89), general female workers(n=79; nurses, insurance counselors, public officials, clerks, etc), and telephone directory assistance operators(n=113). Results from univariate analyses indicated that all demographic factors, all confounders, scores for decision latitude and social support were not associated with the risk of musculoskeletal disorder. However, score for job demand was higher in musculoskeletal disorder cases than others. In subgroup analysis, this association was convinced again, in telephone directory assistance operators. Job strain model showed that the group of telephone directory assistance operators was high-stain group, and OR of musculo skeletal disorder was 2.446(95% C. I. : 1.174, 5.096), when comparing this with the low strain group. In conclusion, job strain is a risk factor for work-related musculoskeletal disorder.

      • KCI등재

        Cloning of metK from Actinoplanes teichomyceticus ATCC31121 and Effect of Its High Expression on Antibiotic Production

        ( Du Yeong Kim ),( Yong Il Hwang ),( Sun Uk Choi ) 한국미생물 · 생명공학회 2011 Journal of microbiology and biotechnology Vol.21 No.12

        A metK gene encoding S-adenosyl-L-methionine synthetase was cloned from the non-Streptomyces actinomycetes, Actinoplanes teichomyceticus ATCC31121. In order to evaluate the effect of the metK expression on antibiotic production in actinomycetes, an expression vector harboring the metK gene was constructed and introduced into Streptomyces lividans TK24 and A. teichomyceticus, and the antibiotic production of the exconjugants was assessed. As a result, it was determined that the expression of metK induced 17-fold and 2.2-fold increases in actinorhodin production from S. lividans TK24 and teicoplanin production from A. teichomyceticus, respectively, compared with the control strains.

      • 산림인증의 도입이 국내 목재시장에 미치는 영향

        서영완 ( Yeong Wan Seo ),이주람 ( Ju Ram Lee ),최정기 ( Jung Kee Choi ),차두송 ( Du Song Cha ) 한국임학회 2014 산림과학 공동학술대회 논문집 Vol.2014 No.-

        본 연구는 접경지역인 강원도 인제군과 양구군 DMZ 일원의 민북지역 산림을 대상으로 산림자원 현황을 파악하고 향후 인제군과 양구군 민북지역의 산림관리계획을 위한 DB를 구축하기 위하여 수행되었다. 산림조사를 위하여 임시표본점 138개를 설치하였으며, 임상, 경급, 수종분포 현황을 조사. 분석하였다. 그 결과 임상의 경우 활엽수림이 126개(91.3 %)로 가장 많은 것으로 나타났으며, 혼효림과 침엽수림은 각각 8개(5.8%)와 4개(2.9%)로 나타났다. 흉고직경의 경우 소경목(흉고직경 6~18 cm)과 중경목(흉고직경 18~30 cm)이 각각 83.5 %, 15.1%로 대부분을 차지하는 것으로 나타났으며, 대경목(흉고직경 30 cm 이상)은 1.5 %로 나타났다. 한편, 임상별 평균임목재적을 살펴보면, 침엽수가 109.7 ㎥/㏊으로 가장 높게 나타났으며, 혼효림은 96.4 ㎥/㏊, 활엽수는 92.7 ㎥/㏊으로 가장 낮게 나타났다. 이는 임상별 직경분포에서 나타난 바와 같이 중경목과 대경목의 비율이 침엽수림>혼효림>활엽수림으로 나타난 것과 일치하고 있다. 표본점의 입목 수를 바탕으로 출현수종을 산출한 결과 총 41개의 수종을 확인 할 수 있었으며, 상위 10개 수종은 신갈나무, 물푸레나무, 소나무, 신나무, 아까시나무, 박달나무, 가래나무, 버드나무, 느릅나무, 물박달나무로서 전체의 69.7%를 차지하였다. This study was carried out to establish the data base for forest management plan of DMZ region of Inje-gun and Yanggu-gun, Kangwon province through inventoring the forest resources of the region. A total of 138 temporary plots were installed to inventory and analyze forest type, dbh class and species distribution. The result showed that broad leaved forests ccurred the most at 91,3%, followed by mixed forests (5.8%) and coniferous forests (2.9%). mall dbh class trees (6 cm≤dbh≤18 cm) consisted of 83.5% of the total, middle dbh class(18cm≤dbh≤30 cm) 15.1% and large dbh class(dbh≥30 cm) 1.5%. In terms of growing stock per ha by forest type coniferous forest was the highest of 109.7 ㎥/㏊, followed by mixed forest (96.4 ㎥/ ㏊) and broad leaved forest (92.7 ㎥/㏊). This result consist with the fact that the proportion of middle dbhclass and large dbh class was coniferous>mixed>broad leaved. A total of 41 tree species appeared in the region and the top 10 species were Quercus mongolica, Fraxinus rhychophylla, Pinus densiflora, Acer ginnala, Robinia pseudoacacia, Betula schmidtii, Juglans mandshurica, Salix pseudolasiogyne, Ulmus davidiana, and Betula davurica, which account for 69.7% of the total.

      • SCOPUSKCI등재
      • SCISCIESCOPUS

        Enhanced Neurite Outgrowth by Intracellular Stimulation

        Kim, Ilsoo,Lee, Hye Yeong,Kim, Hyungsuk,Lee, Eungjang,Jeong, Du-Won,Kim, Ju-Jin,Park, Seung-Han,Ha, Yoon,Na, Jukwan,Chae, Youngcheol,Yi, Seong,Choi, Heon-Jin American Chemical Society 2015 NANO LETTERS Vol.15 No.8

        <P>Electrical stimulation through direct electrical activation has been widely used to recover the function of neurons, primarily through the extracellular application of thin film electrodes. However, studies using extracellular methods show limited ability to reveal correlations between the cells and the electrical stimulation due to interference from external sources such as membrane capacitance and culture medium. Here, we demonstrate long-term intracellular electrical stimulation of undamaged pheochromocytoma (PC-12) cells by utilizing a vertical nanowire electrode array (VNEA). The VNEA was prepared by synthesizing silicon nanowires on a Si substrate through a vapor–liquid–solid (VLS) mechanism and then fabricating them into electrodes with semiconductor nanodevice processing. PC-12 cells were cultured on the VNEA for 4 days with intracellular electrical stimulation and then a 2-day stabilization period. Periodic scanning via two-photon microscopy confirmed that the electrodes pierced the cells without inducing damage. Electrical stimulation through the VNEA enhances cellular differentiation and neurite outgrowth by about 50% relative to extracellular stimulation under the same conditions. VNEA-mediated stimulation also revealed that cellular differentiation and growth in the cultures were dependent on the potential used to stimulate them. Intracellular stimulation using nanowires could pave the way for controlled cellular differentiation and outgrowth studies in living cells.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/nalefd/2015/nalefd.2015.15.issue-8/acs.nanolett.5b01810/production/images/medium/nl-2015-01810h_0007.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nl5b01810'>ACS Electronic Supporting Info</A></P>

      • KCI등재

        Adrenaline-Cocaine gel의 국소마취 효과

        김옥준,최옥경,이경룡,장석준,구홍두,정성필,하영록,박인철,김승환,심호식 대한응급의학회 1994 대한응급의학회지 Vol.5 No.2

        Lidocaine is commonly used in children as well as adults as a local anesthetics for dermal laceration repair. Local infiltration of wounds with lidocaine(local anesthetics) inflicts pain on pain, particularly distressing in children. To avoid this pain, the use of topical tetracaine-adrenaline-cocaine(TAC) solution and adrenalin-cocaine(AC) gel is proposed. We have evaluated the anesthetic effect of AC gel for minor dermal laceration repair. For three months(Jul to Oct, 1994), the residents of emergency medicine have sutured minor dermal laceration patients who were treated at to the Department of Emergency Medicine, Severance Hospital Yonsei University College of Medicine. The patients population ranged from 9 months to 46 years with an average of 10.2 years. Thirty of the patients were younger than 10 years of age. Lacerations were located on the face in 33 patients and on the scalp in 4 patients. Larger lacerations were encountered in 4 patients. The average dose of AC gel applied per laceration was 0.45 mL(containing 81.9mg cocaine). Two hundred thirty four sutures of total 240 (97.5%) were placed without eliciting any pain. The average anesthetic induction time was 123 seconds. There were no observed adverse reactions with AC gel application or reported complications of wound healing in any patient. Our results support the use of AC gel is an excellent anesthetic effect for dermal laceration.

      • KCI등재

        항파상풍 면역 글로부린의 효과

        김옥준,하영록,최옥경,심호식,장석준,정성필,이경룡,박인철,김승환,구홍두,이정운 대한응급의학회 1994 대한응급의학회지 Vol.5 No.2

        Despite the progress in treatment modality, tetanus still has a high mortality rate. However, the morbidity of tetanus can be decreased through proper prophylactic measures. Although Center for Disease Control(CDC) recommands Td or Td/TIG injection depending on prior immunization state and wound character, TIG alone is being injected to patient with open wound for tetanus prophylaxis in Korea. Therefore, we studied antitetanus antibody titers after injecting 250IU of TIG to evaluate TIG's duration of immunization effect, in vivo. TIG 250IU was injected to 42 healthy adult volunteers and their antitetanus antibody titers were measured at prior to TIG injection, 1 week and 4 weeks after infection. Antibody titers were measured by using ELISA assay with IMMUNOZYM-TETANUS and their results were verified by using the standard t-test. Mean antitetanus antibody titers were 0.167±0.031IU/mL, 0.211±0.031IU/mL and 0.186±0.031IU/mL at before injection, 1 week and 4 weeks after injection, respectively. Antibody titers showed significant difference between values at before injection and 1 week after injection. However, no difference was found between the values before injection and 4 weeks after injection. The practice of injecting TIG 250IU alone for prophylaxis has little effect on maintaining an increased antitetanus antibody titer until 4 weeks after injection.

      • KCI등재

        유아 숲체험교육의 운영실태와 개선방안

        최인화 ( In Hwa Choi ),정영은 ( Yeong Eun Jeong ),허성아 ( Seong Ah Heo ),차두송 ( Du Somg Cha ) 한국사진지리학회 2014 한국사진지리학회지 Vol.24 No.3

        본 연구는 유아 숲체험교육의 운영현황을 살펴보고 이를 활성화하기 위한 개선방안을 파악하기 위하여 학 부모와 교사를 대상으로 자체 숲체험형, 위탁 숲체험형, 일반유치원의 세 집단으로 구분하여 숲체험교육 프로그램에 대한 설문조사를 실시하였다. 설문 분석 결과, 유아 숲체험 프로그램은 복합형 숲체험(자체+위탁형)이 가장 높게 나 타났으며 숲체험 연령은 만3세에서 시작하는 것이 적정한 것으로 조사되었다. 숲체험의 적당한 시간은 2시간이 가장 많았다. 또한 유아 숲체험교육의 개선방안에 대해서는 유아숲지도사 등 전문인력 및 보조인력의 확대와 유아숲체험 장소의 제공 및 체험원의 확대가 많았다. This study suggested the promoting plan through examining the current status of the forest experience education programs for little children. We conducted questionnaire survey for kindergarten parents and teachers on two typical type of forest experience education programs (self forest experience program, entrusted forest experience program, no forest experience program). The results showed that little children are suitable to start forest experience education programs at the age of three years. Also, Two hours were proper times for forest experience education programs for them. The current forest experience programs are necessary to strengthen certified educators and develop improved idea on various type of forest experience programs and places.

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