위 (胃) 내시경 (內視鏡) 검사 (檢査) 14 , 389 예에 대한 임상 (臨床) 연구

함준수(Joon Soo Hahm),박경남(Kyung Nam Park),이민호(Min Ho Lee),이성준(Seong Joon Lee),오수철(Soo Chun Oh),한덕호(Duck Ho Han),이종철(Jong Chul Lee),기춘석(Chun Suhk Kee) 대한소화기학회 1985 대한소화기학회지 Vol.17 No.1

N/A Clinical studies were carried out on 14,389 cases who had taken gastrofiberscopic examination, biopsy and X-ray from May, 1969 to May, 1984 in Han-Yang University Hospital. The results obtained were as follows; 1) Of total 14,389 cases, 7,916 were male and 6,473 were female. 55.1%, of the cases were in the 3rd and 4th decade. 2) Of total 14, 389 cases, 13, 615 showed abnormal endoscopic findings. In abnormal cases, male to female ratio was l.2: l.3) The incidence of single organ involved was 84.8% and multiple organs involved was In single organ involved cases, the most common site of disease was stomach and in multiple organ involved cases, the prevalent sites of lesions were stomach and duodenum. 4) The most frequent disease of stomach was gastritis followed by gastric ulcer. In the cases of duodenum, the most common disease was duodenal ulcer and the next was duodenitis. 5) The most prevalent disease was the chronic gastritis, and the frequency of the other upper gastrointestinal diseases was acute gastritis, gastric ulcer, stomach cancer and duodenal ulcer in orders. 6) The most frequent type of chronic gastritis was superficial gastritis. 7) Among the total cases which had been taken blood-typing, the incidence of most upper gastrointestinal diseases was not related to each blood type. But blood group 0 was common in peptic ulcer disease and blood group A in stomach cancer. 8) The clinical symptoms and signs were of no significant aid for the differential diagnosis of the various upper gastrointestinal diseases.

연속생산설비의 최적 예방보전주기 결정

한철수,김경모 금오공과대학교 산업기술개발연구원 2001 産業技術開發硏究 Vol.17 No.-

For years industrial engineers have been concerned with the design and operation of production system. As the time to repair plant facility is greater than that of the expected and the malfunction of the system is usually resulting in the failure to meet some delivery date, the importance of the efficient maintenance policy in a process plant cannot be underestimated. We develop a preventive maintenance model for the situation, where there are not enough data for regular models previously developed for preventive maintenance, and the effectiveness of the preventive maintenance model proposed in this study is presented with the aid of case problem.

교뇌출혈 환자의 생존에 영향을 미치는 인자에 관한 연구

황선철,김범태,임수빈,신원한 순천향대학교 의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.2

..

1920年代「治安維持法」의 制定ㆍ適用과 '植民地 支配'

韓南濟,金哲秀 경북대학교 평화문제연구소 1995 평화연구 Vol.20 No.-

포항 석병연안에서 삼중자망에 의해 채집된 어류의 종조성 및 양적변동

한경호,손종철,황동식,최수하 한국어류학회 2002 韓國魚類學會誌 Vol.14 No.2

경상북도 포항시 석병 연안에서 삼중자망 5폭을 사용, 1998년 1월부터 12월까지 총 12회에 걸쳐 어류를 포획하여, 어류의 종조성 및 양적변동을 조사하였다. 포획된 어류는 총 1網 7目 27科 58種, 607개체, 93,427g으로 쏨뱅이 目(Scorpaeniformes)과 쏨뱅이 目(Scorpaeniformes) 어류가 총 41種으로 전체 출현종 수의 70.7%를 차지하여 우점하는 분류군이었으며, 科별로는 양볼락 科(Scorpaenidae) 어류가 8種 출현하여, 가장 많은 種이 출현하였다. 개체수에서 우점종은 망상어, 노래미, 쥐노래미, 용치놀래기, 쥐치, 볼락, 개볼락, 멸치 및 임연수어로 이들 9種이 전개체수의 62.9%를 차지하였다. 생체량에서 우점종은 망상어, 쥐노래미, 임연수어, 노래미, 볼락 및 용치놀래기로 이들 6種이 전생체량의 58.4%를 차지하였다. 출현 개체수와 생체량은 수온이 상승하는 4월과, 고수온기인 7월 및 10월에 높게 나타났으며, 저수온기인 1월에는 낮게 나타나, 수온과 밀접한 관계가 있었다. 월별 출현종수는 수온이 낮은 1월에 10種이 출현하여 가장 적었고, 수온의 상승폭이 큰 5월에 24種으로 가장 많았다. 종 다양도지수는 1.640~2.594의 범위로 경월변화가 적고, 인근 해역에 비해서 높은 지수를 나타내고 있어, 다양한 어종과 안정된 군집구조를 형성하고 있는 것으로 나타났다. 본 조사해역에서 연 중 출현한 어종은 망상어, 노래미, 쥐노래미, 볼락 등이며, 체형이 크고 성장도가 양호할 뿐만 아니라 주거종으로서 경제성있는 어종으로 평가된다. Fishes were collected by trammel net to determine seasonal species composition and biomass in coastal waters of Seokbyeong, Pohang, Gyeongsangbuk-do from January to December, 1998. A total of 607 fishes(93,427g) was sampled and classified into 58 species belonging to 27 families and 7 orders. The most dominant orders were Scorpaeniformes and Perciformes, which together accounted for 70.7% of the total. The most dominant family Scorpaenidae was represented by eight species. The dominant species were Ditrema temmincki, Hexagrammos agrammus, H. otakii, Halichoeres poecilopterus, Stephanolepis cirrhifer, Sebastes inermis, Sebastes pachycephalus, Engraulis japonicus and Pleurogrammus azonus; they accounted for 62.9% of the total fishes collected. The dominant species in biomass were Ditrema temmincki, Hexagrammos agrammus, H. otakii, Halichoeres poecilopterus, Sebastes inermis and Pleurogrammus azonus. Those species accounted for 58.4% of the total biomass. The number of individuals and the biomass were much higher in summer and autumn than in winter and spring, and closely correlated with water temperature. Monthly number of species was highest in May, with 24 species and lowest in January, with 10 species. The highest diversity index was in June(H'=2.594), and lowest in January(H'=1.640). The diversity index was 1.640~2.594, with little monthly fluctuation. The diversity index in coastal waters of Seokbyeong was higher than that in other coastal waters. It suggest that the cluster structure may be stable.

결핵의 진단법으로서 중합효소 연쇄반응 검사의 가치

서상철,은상진,김한길,송경은,서장수,최성만,이원길,김재식,김중명 慶北大學校 醫科大學 1994 慶北醫大誌 Vol.35 No.1

목적 : 결핵균 동정을 위한 중합효소 연쇄반응을 임상병리검사로서 적용하기 위한 기초 실험으로 분석학적 예민도와 특이도를 알아보고 검토된 조건에 의한 중합효소 연쇄반응을 실제 임상 가검물에 적용하기 위함이다. 재료 및 방법 : Ziehl-Neelsen염색 양성인 객담, 뢰벤스타인-젠센(Loewenstein-Jensen) 배지에서 분리된 결핵균 및 M. tuberculosis H37Rv를 비롯한 항산균 표준균주 11주와 비항산균 10주를 사용하여 2가지 DNA의 분리법, 3set 프라이머, 3종류 중합효소, 2가지 미량 원심시험관 및 Easy-Cycler^R(Ericomp사, 미국)와 수조형으로 검사를 시행하여 DNA 증폭 산물을 비교하였다. 또한 이미 지일-닐슨 염색법에 의한 선별검사에서 음성을 나타낸 객담 53예, 소변 101예, 삼출액 128예, 뇌척수액 54예 등 총 370예의 임상가검물을 대상으로 하여 위에서 검토된 중합효소 연쇄반응 조건으로 검사한 성적과 지일-닐슨 염색법, 배양법 성적과 비교하였다. 결과 : DNA분리방법 2가지와 3가지 중합효소는 분석학적 예민도와 5fg로 나타나 차이를 발견할 수 없었으며, 프라이머 P1, P2쌍은 예민도가 5fg, 프라이머 INS1, INS2쌍과 프라이머 Pt3, Pt6쌍의 예민도는 0.5fg이었다. Easy-Cycler^R가 수조형에 비해 높고, 미량 원심시험관은 Robbins사 제품이 Sarstedt사 제품에 비해 높은 분석학적 예민도를 나타냈다. 프라이머 P1, P2쌍과 프라이머 INS1, INS2와 Pt3, Pt6 2쌍의 프라이머의 특이도에 있어서는 항산균 표준균주 중 M. tuberculosis H37Rv, M. tuberculosis ATCC 27294, M. bovis ATCC 29312의 3주에서 특이 증폭 띠를 관찰할 수 있었다. 그러나 비결핵성 항산균 8주에는 특이 증폭 띠를 나타내지 않았다. 또 비항산균 10주에도 특이 증폭 띠가 관찰되지 않았다. 따라서 Robbins사의 미량 원심시험관과 proteinase-K법에 의한 DNA분리방법에 Easy-Cycler^R를 사용하여 프라이머 INS1, INS2쌍으로 일차 중합효소 연쇄반응을 시행한 후 프라이머 Pt3, Pt6쌍으로 이차중합효소 연쇄반응을 시행하는 방법을 370예의 임상가검물에 시행하였고 지일-닐슨 염색법과 결핵균배양검사도 동시에 시행한 결과 중합효소 연쇄반응 양성은 106예(28.6%), 배양 양성은 27예(7.3%) 및 염색 양성은 18예(4.9%)였으며, 결핵환자는 141명(38.1%)였다. 370예의 임상 가검물로 시행한 중합효소 연쇄반응의 진단학적 예민도와 특이도, 양성결과 예측치 및 음성결과 예측치는 68.8%, 96.1%, 91.5% 및 83.3%로 각각 나타났다. 결론 : 결핵균 동정을 위한 중합효소 연쇄반응은 배양검사에 비해 신속하며, 분석학적인 예민도와 특이도가 뛰어나므로 결핵 진단을 위한 임상병리검사로서 유용하다고 사료됨. In this study, We investigated the optimal conditions of polymerase chain reaction(PCR) assay for the rapid identification of Mycobacterium tuberculosis in clinical specimens as routine laboratory test. So we have compared two DNA isolation methods, 3 polymerases, 2 set of primer, 2 kinds of thermocycler and 2 microtubes. We evaluated two DNA isolation methods, bead-beating method and proteinase-K method, the latter was more sensitive than the former. In comparision of two sets of primers, P1 and P2 primers detecting 123-base pair fragment of IS6110 made from Biosnthesis(U. S. A.) and INS1 and INS2 primers detecting 245-base pair fragment of IS986 showed equally sensitive results ie. 5fg. Specificity of primers were tested and INS1 and INS2 primers gave 245-base pair product from M. tuberculosis H37Rv, M. tuberculosis ATCC 27294 and Mycobacterium bovis ATCC 29312 but not from 8 nontuberculous mycobacterial strains such as M. kansasii ATCC 12478, M. terrae ATCC 15755, M. intracellurae ATCC 13950, M. avium ATCC 25281, M. gordonae ATCC 14470, M. fortuitum ATCC 6841, M. smegmatis ATCC 19420, M. scrofulaceum ATCC 19981. Coagulase-positive staphylococcus, coagulase-negative staphylococcus, streptococcus, Esccherichia coli, Serra-tia marcescens, Klebsiella pneumoniae, Enlerobacter aerogenes, Enterobacter cloacae, Acinetobacter calcoaceticus, Pseudomonas aerugonosa showed no 245-base pair amplification product. PCR by the P1 and P2 primers showed 123-base pair amplification product from M. tuberculosis H37Rv, M. tuberculosis ATCC 27294 and Mycobacterium bovis ATCC 29312 but not from 8 nontuberculous mycobacterial strains such as M. kansasii ATCC 12478, M. terrae ATCC 15755, M. intracellularae ATCC 13950, M. avium ATCC 25281, M. gordonae ATCC 14470, M. fortuitum ATCC 6841, M. smegmatis ATCC 19420, M. scrofulaceum ATCC 19981. Coagulase-postive staphylococcus, coagulase-negative staphylococcus, streptococcus, Escherichia coli, Serratia marcescens, Klebsiella pneumoniae, Enlerobacter aerogenes, Enterobacter cloacae, Acinelobacler calcoaceticus, Pseudomonas aeruginosa showed no 123-base pair amplification product. In comparision of polymerase, Taq DNA polymerase^R(Promega Co., U. S. A.) was more cost effective than Ampli Tag^R(Perkin-Elmer Cetus, U. S. A.), but these two were equally sensitive and specific in the detection of M. tuberculosis-specific DNA. Tac polymerase (Korea'Biotech, Korea) showed many nonspecific bands. In comparision of thermocycler, Easy-Cycler^R(Ericomp, U. S. A.) was more sensitive than water-bath type and in that of microtubes Robbin's were more sensitive than Sarstedt's PCR results were compared with results of culture for M. tuberculosis and Ziehl-Neelsen stain in 370 clinical specimens that were negative by initial Ziehl-Neelsen stain. There were 27 specimens(7.3%) that were positive for M. tuberculosis by culture, 18(4.9%) specimens that were positive by Ziehl-Neelsen stain, and 106 specimens(28.6%) that were positive for PCR and 141 cases that were positive for tuberculosis. Overall sensitivity, specificity, positive predictive value and negative predictive value were 68.8, 96.1, 91.5 and 83.3% respectively, for PCR; 19.1, 100, 100, and 66.8%, respectively for culture; and 12.8, 100, 100, and 59.0% respectively for Ziehl-Neelsen stain.

工場現地化戰略에 관한 硏究

梁漢洙,朴徹敏,朴光日 慶南大學校 産業經營硏究所 1996 産業經營 Vol.19 No.-

MRP II 시스템의 適用方案에 관한 硏究

朴徹敏,梁漢洙 慶南大學校 産業經營硏究所 1989 産業經營 Vol.12 No.-

외상에 의한 지연성 뇌경색 2예 : Case Reports

김수일,김헌주,한용표,홍순기,허철 대한신경외과학회 1989 Journal of Korean neurosurgical society Vol.18 No.5

Delayed traumatic cerebral infarction appears to occur more frequently than previously expected. We have experienced two cases of this clinical entity whose initial neurological condition were good except headache and/or mental confusion. However, their initial Brain CT scans showed no specific abnormalities. The detailed neurological examination and follow up Brain CT scans were prerequisite choices of strategy against this type of lesion. However, additional studies regarding intracranial pressure(ICP), cerebral blood flow(CBF), multimodality evoked potential(MMEP) and magnetic resonance imaging(MRI) should be considered as an alternative armamentarium for further elucidation of vascular insults to already injured brain.

집파리(Musaca domestica L)에 對한 防疫用 殺蟲劑의 毒性效力에 對한 評價

沈載澈,李鍾秀,李漢一,蔡和秉 國立保健硏究院 1977 국립보건연구원보 Vol.14 No.-