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      • SCISCIESCOPUSKCI등재
      • 급성전골수성백혈병에서 백혈구성분채집술에 이은 치명적인 뇌출혈 2예

        오윤정,박소윤,김윤정,한동석,김현수,최진혁,남동기,임호영,김효철,주희재 아주대학교 의과학연구소 1998 아주의학 Vol.3 No.1

        The aim of this study is to report 2 cases of acute promyelocytic leukemia who died from intracranial hemorrhage following leukapheresis and to provide proper preventive measures against hemorrhage following leukapheresis. From 1994 to 1997, a total of twenty-six patients with leukemia underwent leukapheresis to control hyperleukocytosis at Ajou University Hospital. Two patients with acute promyelocytic leukemia received all-trans retinoic acid but developed drug-induced hyperleukocytosis. Shortly after leukapheresis, they died from intracranial hemorrhage. The risk factors for fatal hemorrhage are thought to be coexisting disseminated intravascular coagulation(DIC), thrombocytopenia aggravated by leukapheresis, exacerbated coagulopathy related to mechanical trauma through leukapheresis and the excess use of citrate during leukapheresis. To reduce the risk of the bleeding associated with leukapheresis, it is necessary to replace platelet sufficiently before and after leukapheresis and to give calcium to correct coagulopathy induced by excess citrate which is used as anticoagulant as well as the correction of disseminated intravascular coagulation.

      • KCI등재

        Cr, Co, Cu, Ni와 Ca의 첨가에 따른 지하매설배관의 전기화학적 특성에 관한 연구

        최윤석,신동호,심재주,김정구 대한금속재료학회 2005 대한금속·재료학회지 Vol.43 No.1

        Aqueous corrosion characteristics of low carbon steel with small amounts of Cr, Co, Cu, Ni and Ca, in synthetic groundwater was studied by electrochemical corrosion tests (potentiodynamic test and electrochemical impedance spectroscopy (EIS) measurements) and analytical techniques. Neither carbon steel nor newly alloyed steels showed passive behavior in this synthetic groundwater. Newly alloyed steels, containing Cr-Co, Cr-Cu-Ni and Cr-Cu-Ni-Ca showed higher corrosion resistance than carbon steel in the potentiodynamic tests. EIS measurements showed that the Nyquist plot presented two time constants. The high frequency resistance component (R_(rsut)) and low frequency resistance component (R_(et)) were affected by the alloying elements. The polarization resistance (RP= R_(et) +Ra) of steels could be clearly ranked as Cr-Cu-Ni-Ca steel >> Cr-Cu-Ni steel > Cr-Co steel > carbon steel. Results of surface analyses (XPS and EPMA) showed that Cr and Cu were concentrated in the inner region of rust. However, Co and Ni were uniformly distributed all over the rust layer. These alloying elements improved corrosion resistance of low alloy steel in synthetic groundwater. Especially, Cr-Cu-Ni-Ca steel had the lowest corrosion rate due to the inner rust film formation during the initial stage of corrosion, which suggested a potential for substituting carbon steel in soil environment (Received October 29, 2004)

      • 노인의 영적 간호요구

        최미혜,김경희,김귀옥,김기숙,김수강,김정신,김춘숙,노흥진,박지연,성혜연,오명선,이선희,이원옥,이윤영,이현수,장명재,차혜경,채정선,홍상희 중앙대학교 의과대학 간호학과 간호과학연구소 2001 중앙간호논문집 Vol.5 No.1

        This study was designed to exam the aged's needs for spiritual nursing care. The purpose was to serve as a basis for the development of spiritual nursing practice. The major findings are as follows : 1. The degree of needs for spiritual nursing care as area was that needs of love and relationship mean 22.0, needs of meaning and object mean 28.2, needs of forgiving mean 13.5. Total needs for spiritual nursing care mean 63.7, which was on the upper middle level. The needs of meaning and object was rated highest. 2. Among the general characteristics of the subjects, needs of love and relatiohship wasn't significanlty different. 3. Among the general characteristics of the subjects, needs of meaning and object was significantly different according to two factors : age(F=7.260, p=0.001), religion(F=5.275, p=0.001). Higher needs of meaning and object was possessed by the older than the younger, by the one who have religion than the other. 4. Among the general characteristics of the subjects, four factors made a significantly difference to needs of forgiving : sex(t=-2.851, p=0.006), age(F=8.201, p=0.001), religion(F=6.928, p=0.000), disease(t=2.327, p=0.024). Higher needs of forgiving was possessed by man than woman, by the older than the younger, by the one who have religion than the other, by the one who have disease than the other.

      • 항암제(Adriamycin, Cyclophosphamide, 5-Fluorouracil)로 유발된 흰쥐의 간독성에 대한 Squalene의 효과

        최영복,김종세,윤중식 조선대학교 기초과학연구소 1998 自然科學硏究 Vol.21 No.1

        The objective of the present study was to investigate the cytotoxicity of Adriamycin〔ADM〕. Cyclophosphamide〔CP〕, 5-Fluorouracil〔5-FU〕 in mouse liver cells (group A, B, c), and the protective effect of squalene to the hepatocytes to which ADM, CP, and 5-Fu-induced cytotoxicity(group A-1, B-1, C-1) was examined by transmission electron microscope. In the group A, The cisternae of rough endolplasmic reticulum(RER) and smooth endoplasmic reticulum(SER) are dilated/disoriented at 24 hours and 48 hours. The inner and outer membrane of mitochondria are detached or destructed, and attached ribosomes of RER are diminished in number. The cisternae of the SER are dilated, and the cristae of mitochondria are disrupted at 72 hours and 96 hours. In the group A-1, the cisternae of the RER and the SER are dilated at 24 hours. The cisternae of the SER are dilated at 48 hours. The cell organelles of hepatocytes are recovered from cytotoxicity at 72 hours. At 96 hours, hepatocytes were simillar to those of normal hepatocytes. In the group B, the cisternae of RER were partially destructed and attached ribosomes were remarkable decreased at 24 hours. A number of the mitochondria were dilated and increased in number, the filamentous materials also detected at 72 hours. In the group B-1, the difference between the normal and the treated groups were not detected at 24 hours, but the few mitochondria were expanded at the 72 hours. In the group C, the nucleus was destroyed at 24 hours and 48 hours group, however, somewhat repaired at 72 hours group. The dilated inner cavity and the irregular lamellae of the RER were observed continually until 72 hours group. The inner cavity of the SER were dilated in all groups. However, the destroyed and the normal membrane were observed simultaneously at 72 hours group. The inner membrane of the mitochondria were almost repaired at 96 hours group. In the group C-1, the nucleus was a little finfluenced by the toxicity of 5-Fu at 24 hours and 48 hours, RER were observed to keep the typical lamella structure of cisternae from 24 to 72 hours group, but inner cavity kept on dilating. In SER, inner cavity were also observed to flatten from 24 to 72 hours group. Mitochondria were always shown normal. All cell organelles were similar to those of normal at 96 hours. Accordingly, it can be said that the treatment of SQ prevents the cytotoxicity of ADM, CP, 5-FU on cell organelles of liver cell and that is concerned with the formation of membrane system of cell organelles.

      • KCI등재

        SJO¨GREN'S SYNDROME 환자에게 즉시 임프란트 술식을 행한 치험례

        최정환,손동석,이지연,이윤서,안선희,이재목 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.5

        The old edentulous patients experience xerostomia commonly. They have considerable difficulty in wearing tissue-supported prosthesis and high risk rate of caries. One of them is Sj□gren's syndrome patient. Sj□gren's syndrome is a chronic inflammatory autoimmune disorder that results in a lymphocyte-mediated destruction of exocrine glands. We planned to place implants immediately after extraction in this case of autoimmune disease. The advantages of immediate implant placement include considerable decrease in time from tooth extraction to placement of the final prosthesis, fewer surgical procedures, and better acceptance of the overall treatment plan. We present a case of Sj□gren's syndrome patient treated with immediate implant placement & immediate loading in anterior region and immediate implant placement in posterior region.

      • 서울 및 경기지역 노인의 신체적 건강 및 기능적 건강 실태 조사

        최윤정;박유신;이상선 한양대학교 2010 韓國 生活 科學 硏究 Vol.30 No.2

        This study was performed to assess anthropometric status, functional health and physical fitness among the elderly in Seoul and Kyunggi-do. Four hundred forty free-living elderly people(127 male, 331 female), aged 65 or more were interviewed by trained interviewers using structured questionnaires including demographic information, activities of daily living(ADL), instrumental activities of daily living(IADL), physical activity. And they measured anthropometic status and physical fitness. All the data were analyzed by student t-test, chi-square analysis using SPSS 9.0 version at p<0.05. The results can be summarized as follow : Of all the subjects, 46.3% were obesity, especially 92.4% of female were abdominal obesity. In functional health status, ADL score was 6.62±1.54, and IADL score was 25.94±6.92. Most of the subjects were difficult to walk and run. Female was a significantly higher flexibility and body fat than male(p<0.001), whereas female was a significantly lower muscular endurance than male(p<0.001).

      • KCI등재

        아파트 전면발코니의 실내환경 조절효과 및 공간기능

        최윤정 대한가정학회 2004 Family and Environment Research Vol.42 No.5

        The purpose of this study is to make clear the indoor envirwunental efficiency and spatial function of the front balcony in apartments using responses from residents'. An interview survey carried out during the l4th ~24th of January 2003, and a questionnaire survey was given during the 17th-29th of January. Intervhwes consisted of 31 residents living in renovated apartments, which had the front &ny added onto the living mom. The respondents of the questionnaire survey consisted of 37 residents living in ordinary apartments with an existing front balcony. The residents living in o r d i i apartments show relatively positive responses on the indoor thermal environment during winter, glare by daylight, and outdoor noise. The average heating cham of the renovated apartments came out to be more expensive than the ordinary apartments. In most renovated apartments, rhe living area converted from front balcony was used as the same functions ('space for dying the laundry', 'storage space', or 'space for cultivating of flower pots') of ordinary front balcony. From the results of this study, it is undesimbie to renovate the front balmy as an addition to the Ikringroom.

      • 서울지역 복지회관의 결식아동의 영양적 건강상태

        최윤정;박유신;장유경 한양대학교 2004 韓國 生活 科學 硏究 Vol.- No.24

        This study was carried out to investigated the growth development and nutritional health of poorly-fed children in Seoul Welfare Center. All subjects underwent a structured interview for general characteristics, anthropometric measurement and nutritional status. The results are as follows : The subjects were 30(male : 14, female : 16), among 7 to 12 years old. In higher grade boy, physical growth and development were decreased. Among the subjects, 37.7% were skipped the breakfast. In food group frequencies, subjects had animal protein such as meats(82.1%), fish(58.6%), and vegetable protein such as legumes(73.3%) 2 times and less a week. The average intakes of energy, vitamin B2, calcium were below 75% of the recommended dietary allowance. More than half of the subjects were under-nutrition (deficient of RDA, below 75%) in energy, vitamin A, vitamin B2, niacin, calcium and iron. Consequently, for balanced growth and development, it is necessary for school or community based nutritional support to supply dairy products that are major source of vitamin B2 and calcium for poorly-fed children.

      • KCI등재

        How Young Consumers Perceive Firms’ Environment, Social, and Governance (ESG)

        Choi,Woo Jin,Yoon,Ho-Jung 한국상품학회 2021 商品學硏究 Vol.39 No.6

        Demand for ESG is surging. However, not many are known regarding how consumers perceive firms’ ESG. To fill this gap in the literature, the current research seeks to explore how firms’ ESG is perceived by the young generation as well as to explore how the young generation perceive South Korean firms from the ethical perspective. For this purpose, we surveyed ninety-two respondents (35.8% male; Mage=23.5) and they completed the survey. In the survey, respondents indicated their perception regarding South Korean firms’ ethical business management and South Korean firms’ ESG management. Most respondents said ESG would be important (88%) and helpful to achieve competitive advantage (81.5%). However, interestingly, almost of respondents (46.7%) said that ESG would be helpful to maximize productivity. Rather, 92.4% of respondents perceived that ESG would be helpful to enhance firms’ images. In addition, they also perceived that the importance of ESG would become great in the future (85.9%) enough to make a significantly positive impact on firms’ productivity (72.8%). In addition to these findings about ESG, we further investigated how this young generation perceived the ethical business climate among South Korean companies. The results show that only 17.3% of respondents said South Korean business is ethical and 70.6% thought ethical problems would be a problem in the future. While the investigation for South Korean consumers’ perception of ESG and ethical business is not many, our work makes a significant theoretical contribution by providing empirical evidence on this issue. Our results are also managerially meaningful by being a reference to South Korean companies as well as global companies who are interested in the Korean market.

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