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식도정맥류 출혈의 치료에 대한 비용 대비 효과 - Modified Sugiura Procedure와 내시경적 치료의 비교 -
배병노 ( Byung Noe Bae ),양근호 ( Keun Ho Yang ),김홍용 ( Hong Yong Kim ),김기환 ( Ki Hwan Kim ),한세환 ( Se Hwan Han ),김홍주 ( Hong Joo Kim ),김영덕 ( Young Duck Kim ),신원창 ( Won Chang Shin ) 대한소화기학회 2003 대한소화기학회지 Vol.41 No.4
Background/Aims: According to current studies, the patients treated with modified Sugiura procedure show lower rebleeding rates compared with endoscopic therapy. The aim of this case-control study was to compare modified Sugiura procedure (transabdominal esophageal transection plus esophagogastric devascularization plus splenectomy) with endoscopic therapy for the prevention of recurrent variceal bleeding. Methods: Twenty patients were treated with surgery and 22 patients were treated with endoscopic therapy. We compared their outcomes. Measured main outcomes were mortality, variceal rebleeding, post-interventional changes of liver function, total hospital days, and total hospital charges. Results: Overall mortality in this series was not different. Bleeding related mortality and encephalopathy in the endoscopic therapy group were slightly higher than those in the surgery therapy group. However, these differences were not statistically significant. In patients treated with the modified Sugiura procedure, the liver function was remarkably improved after the operation. Rates of rebleeding (p<0.001), requiring additional endoscopy (p=0.016) and rehospitlalizations (p=0.008) were higher in endoscopic therapy group. In spite of initial lower cost, the overall costs of endoscopic therapy were higher than those of surgery if the costs for the prevention of variceal rebleeding was included. Conclusions: These results indicate that modified Sugiura procedure for esophageal variceal bleeding could improve therapeutic efficiency and quality of life of the patient, especially in the patients with good liver reservoir function. (Korean J Gastroenterol 2003;41:302-308)
림프관 침윤이 있는 stage II 대장암 환자와 국소림프절 전이가 N1인 stage III 환자의 보조적 항암요법의 결과 및 예후
박재현(Jae Hyun Park),배병노(Byung Noe Bae),안훈(Hoon An),박인석(In Seok Park),조현진(Hyun Jin Cho),곽금희(Geum Hee Gwak),양근호(Keun Ho Yang),김기환(Ki Whan Kim),한세환(Sehwan Han),김홍주(Hong Ju Kim),김영덕(Young Duk Kim) 대한종양외과학회 2013 Korean Journal of Clinical Oncology Vol.9 No.2
Purpose: Guideline of stage II colon cancer chemotherapy is controversial issue. This study aims to assist in making proper guideline of stage II colorectal cancer chemotherapy. Methods: We retrospectively analyzed the medical records of 137 patients who had colorectal cancer surgery and chemotherapy at Sanggye Paik Hospital, Surgical Department from 2008 to February 2013. We analyzed disease-free survival rate (DFS), characteristics and relationship of stage II (II), stage II with lymphatic invasion (IIL), stage III with N1 (lymph mode involvement number under 3). Results: We found new metastasis in 23 patients (liver 11, lung 5, peritoneum 6, bone 1). There is no difference in DFS between II and IIL (P=0.064). But recurrence more frequently appeared with lymatic invasion group. There is no difference in DFS between IIL and III (P=0.083). But cancer stage had not effect to recurrence (P=0.153). In IIL patients, statistically difference did not be shown between oral and intravenous chemotherapy group (P=0.500). But chemotherapy completion group had higher DFS (P=0.001). Conclusion: Between II and IIL, DFS did not have difference but low P-value. In consideration of correlation analysis result and DFS between IIL and III, we think their prognosis is not same and completion of chemotherapy influence on good outcome in stage II with lymphatic invasion colon cancer.