혈행화된 두개골 피판을 이용한 안와저 및 안와하연의 재건술 치험례

정윤규,이훈범,김석원,봉정표,김균태,김주봉 大韓成形外科學會 1998 Archives of Plastic Surgery Vol.25 No.5

A number of methods have been introduced for support the orbital floor following a maxillectomy without orbital exenteration or severe facial trauma. These methods including skin graft and muscular sling provided the unsatisfactory results, like as diplopia, orbital ptosis, enophthalmos and severe facial deformity. Therefore the bone and soft tissue reconstructions using microvascular free flaps were performed recently by many surgeons, but long time operation, donor site morbidity, postoperative large scar, and ptosis of the flap were pointed out as disadvantages of free flap reconstruction. Vascularized calvarial bone flap, a modified method of free calvarial bone graft, was adequate for reconstruction of the orbital floor and the infraorbital rim as a horizontal buttress, especially in case of poor vascular bed and postradiated state. The authors introduced the vascularized calvarial bone flap for the orbital floor and the infraorbital rim reconstruction in 3 cases of maxillectomy, and could be obtained satisfactory results aesthetically and functionally.

고장성 식염수를 이용한 실험적 근육통에서의 통증 양상

손민균,김태민,서정수,김봉옥,윤승호 大韓再活醫學會 2000 Annals of Rehabilitation Medicine Vol.24 No.3

폐결핵치료 중인 환자에서 Rifampicin에 의해 유발된 위막성 대장염 2예

김봉진,권균홍,임창섭,김자영,홍정범,옥미선,배용목,김지연 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.4

Pseudomembranous colitis (PMC) is a disease caused by Clostridium difficile proliferation. The causative drugs are clindamycin, third-generation cephalosporins, flouroquinolone and so on. Rifampicin has been reported as a cause of PMC in the 1980s, and the frequency of PMC is increasing because rifampicin is a first line drug for anti-tuberculosis therapy. Two patients were recently admitted to our hospital due to watery diarrhea for 1 month and they were diagnosed with PMC by sigmoidoscopy. Their onset age were 74, 72 years old and latent period of symptoms were 60, 129 days, respectively. In one case, the patient displayed coexisting hypertension and diabetes. The clinical symptoms improved after discontinuing the rifampicin and then administering oral metronidazole. We report here on two cases presumed to be rifampicin-induced PMC.

척수손상 환자의 합병증

김봉옥,박상균,남명호,윤승호 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.2

To evaluate the rehabilitative care needs of the patients with spinal cord injury in this regional area, the complications which were seen in the department of rehabilitation medicine in Chungnam National University Hospital during the 1st year since the opening of the isolated rehabilitation medicine ward in September 1989 were analyzed. The study population was consisted of 25 men and 2 women. Nine cases (33.3%) were in the 20-29 age group and 11 cases (40.8%) were injured by traffic accident, the most common cause of traumatic spinal cord injury in this study. Sixteen cases(59.2%) were paraplegics and eleven cases(40.8%) were quardriplegics. The duration from the onset of injury to admission to the department of rehabilitation medicine ranged from 21 days to 14 years with mean of 18 months. The complications seen in this study were as follows. 1. Urinary tract infections, most common complication, were found in 14 cases (51.6%) followed by decubitus ulcers (44.4%), edema of leg (22.2%), spasticity (18.5%). 2. The most common organism of urinary tract infection was E.coli(43.0%). 3. Among the 22 cases which underwent IVP and VCUG, 2 cases showed hydronephrosis in IVP and 4 cases showed vesicoureteral reflux in VCUG. 4 The most common site of pressure sores was sacrum(53.3%). 5. The mean duration of pressure sore healing with non-surgical treatment was 18 days in Grade II and 42 days in Grade III. With the above results, it is concluded that most frequent complications of patients with spinal cord injury were urinary tract infection and pressure sores, with most of them being occurred before the admission to department of rehabilitation medicine and being treated completely during the stay in the department of rehabilitatiom medicine, and that the comprehensive rehabilitation treatment for the prevention of complications is necessary from the onset of injury.

牧丹皮가 Collagen 誘發 關節炎에 미치는 影響

金東赫,宋峰根,金炯均 한국전통의학연구소 1997 한국전통의학지 Vol.7 No.2

류마티스관절염은 활막관절 부위의 만성 염증을 특징으로하며 병이 진행될에 따라 이환된 관절의 연골 및 골과 관절주위 연체조직의 파괴를 초래하는 전신성 자가면역질환이다. 전세계에 걸쳐서 주로 젊은층에서 발병하며 전 인구의 약 2-4%가 이환되는 것으로 알려진 류마티스관절염의 병인에 대하여는 아직도 완전히 규명되지 못하고 있으며,이 질병을 완치 시키거나 질병의 질행을 막을 수 있은 치료법이 정리되지 않은 실정이다. 牧丹皮는 淸熱凉血 活血祛瘀의 효능이 있어 임상적으로 발열,도한,월경불순등 이나 급성충수염 또는 跌打瘀血 등에 응용되어 왔으며 최근에는 진정,최면,진통작용과 항염 및 항알레르기 작용 등이 보고되고 있고 adjuvant 관절염에서 염증반응을 억제하는 것으로 보고되고 있다. 목단피가 콜라겐유발관절염(CIA)에 미치는 영향을 알아보기 위하여 bovine type II collagen을 랫트의 꼬리에 주사하고 목단피를 투여하여 CIA의 유발과정중의 면역학적 변화에 미치는 영향에 대하여 관찰하였다. 그 결과 목단피는 생체내와 생체외에서 담식세포에 의한 탐식능을 증가시켰으며 활막세포에 의한 반응산소중간물질 생성능을 감소시켰다. 또한 목단피는 림프구의 증식을 억제하였고,CD4+세포의 비율을 증가시키고 CD8+세포의 비율을 감소시켰다. 아울러 목단피는 요증 미tric oxide(NO)의 분비를 억제시켰고, 활막세포에서의 NO생성을 약간 증가시키는 효과를 보였으나 고농도의 목단피를 투여할 경우 다시 감소하는 결과를 보였다. 이상의 결과로 볼 때 collagen에 의한 관절염의 진행시 목단피의 투여는 면역반응을 조절하여 ROI와 NO의 생성을 억제하고 탐식능을 증가시켜 외부 항원에 대한 탐식을 효과적으로 하여 관절염의 진행을 완화시킨 것으로 생각되며,따라서 목단피는 류마티스관절염의 치료에 임상적으로 활용할 수 있을 것으로 사료된다. Rheumatoid arthritis(RA) is an autoimmune disorder characterized by a chronic inflammatory, proliferative polyarthritis with joint destruction. The disease occurs throughout the world. Most cases are common in young adult age, and 2-4% of the population are affected with female predominance. However the curative therapy of RA is not yet available, so the development of successful management is required. Moutan Cortex is an herb drug applied for such disease as fever, sweating, menstrual irregularity, acute appendicitis and trauma. Recently it is reported that Moutan Cortex has the antiinflammatory, antimicrobial and antihypertensive actions. It also has analgesic, sedative, and anticonvulsant effects. And it is reported to inhibil swelling of rat's paw and reduce arthritic joint swelling. So as to investigate the effects of Moutan Cortex on collagen-induced arthritis, its water extract was administered in the rat immunized by collagen and the immune responses were measured. The phagocytosis was increased in vivo and in vitro after administration of Moutan Cortex, which was strikingly increased after secondary immunization in vivo. Moutan Cortex decreased lhe reactive oxygen intermediate(ROI) formation and nitric oxide(NO) secretion in urine. While formation of reactive nitrogen intermediate was slightly increased after administration, it showed tendency of decrement in high dose. Moutan Cortex also inhibit lymphocytes proliferation. The ratio of CD4+ T cell was decreased and CD8+ T cell was increased. These results suggest that Moutan Cortex might inhibit arthritic changes by regulating immune response, inhibiting ROI and NO formation and increasing phagocytosis. So Moutan Cortex could be applied for the treatment of RA.

加味牛膝湯이 實驗動物의 鎭痛에 미치는 影響

金炯均,權文鉉,오로사,金成宰,李彦政,李峰根 圓光大學校 韓醫學硏究所 1996 원광한의학 Vol.6 No.1

急性特發性心囊炎의 1例

金星潤,孫宜錫,李禎均,許鳳烈,咸駿洙,金鮮宙 대한의학협회 1977 대한의학협회지 Vol.20 No.9

편도절제술을 받는 소아에서 수술 후 오심 및 구토에 대한 Propofol과 Ondansetron의 예방적 효과

김영재,구봉근,이정한,이근무,정순호,최영균,신치만 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Objective: To examine the prophylactic effect of ondansetron and propofol against postoperative nausea and vomiting(PONV) in children undergoing tonsill ectomy Methods and Materials: Sixty children(aged 3-11 years) who underwent tonsillectomy received antiemetics (ondansetron group; ondansetron 0.1mg/kg, propofol group; propofol 0.5mg/kg) or not (control group) at the end of surgery. Anesthesia was induced with ketamine(1mg/kgiv) and rocuronium(0.5mg/kg) and maintained by inhalation anesthesia with 2-3vol% sevoflurane in 50% N_(2)O/O_(2). Premedication was given as atropine 0.01mg/kg iv. Ketorolac(1mg/kg) was injected for postoperative analgesia immediate after induction. They were monitored the incidence of PONV at operation room, postanesthetic care unit(PACU) and admission room. Results: No significant differences were observed in the total incidence of PONV among the groups. But ondansetron and propofol group made a difference(p<0.05) in the incidence of PONV at operation room compared with control group. Conclusion: In children undergoing tonsillectomy, ondansetron(0.1mg/kg) and propofol(0.5mg/kg) may have a prophylactic effect against PONV at operation room.

대전·충남 지역 재가 척수장애인의 재활실태 조사

김봉옥,박상균,방덕영 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

The purposes of this study were to evaluate the status of rehabilitation of spinal cord injured patients and to obtain baseline data for their comprehensive rehabilitation in Taejon and Chungnam area by questionnaire to the spinal cord injured in this area who suffered for 1 year or longer. The study population was consisted of 79 men, and 3 women. The results were as follows. 1. In age distribution, 33 cases(40.2%) were in their fourth decade and 19 cases(23.2%) were in the fifth decade. The causes of the injury were traffic accidents, hit by flying object, falls, and diseases in the order of frequency. 2. Twelve cases(14.6%) were quadriplegics, 70 cases(85.4%) were paraplegics, and 49 cases(59.87%) were job-related injury. 3. Most of the patients experienced various complications such as pain in paralyzed area, spasticity, and urinary tract infections in the order of frequency. 4. Sixty-seven cases(81.7%) were not supported by the goverment's plan to provide orthoses for the disabled with low income. 5. Among architecturaa barriers, the most common limitation to the patients was toilet(51.2%) accessibility. 6. In men responders, 34 cases(75.4%) were unable to pursue sexual intercourse. 7. The most common cause of dependency in ADL was bowel and bladder problem. With the above results, we conclude that 1) establishment of the comprehensive spinal cord injury center, 2) provision of opportunity of the continuous formal education, 3) assistance of productive activities, 4) removal of architectural barriers at home and community, and 5) obligation of registration of the disabled are necessary for the comprehensive rehabilitation of spinal cord injured patients is Taejon and Chungnam region.

積層複合材料의 모우드 Ⅰ層間破壞靭性에 對한 두께의 影響

金載勳,金奉謙 麗水水産大學校 産業技術硏究所 1993 産業基術硏究所 論文集 Vol.2 No.-

This study aimed to provide an energy release rate for carbon/epoxy composite DCB specimen with bending effect. The specimen is used 8mm and 3mm thickness for measuring the Mode I interlaminar fracture toughness. The energy release rate is evaluated by compliance method, area method, beam theory and corrective equation. The average energy release rate is equal to 0.022KJ/mm² when compliance method is applied to 8mm DCB specimen. The average G?? considered bending effect is equal to 0.026 KJ/mm² when the corrective energy release rate equation is applied to 3mm DCB specimen.