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Yuan-yuan Jiang,Lian Sun,Hua Wang,Chun-yang Zhao,Wei-Bing Zhang 대한치과교정학회 2020 대한치과교정학회지 Vol.50 No.2
Objective: To propose a three-dimensional (3D) method for evaluating temporomandibular joint (TMJ) changes during Twin-block treatment. Methods: Seventeen patients with Class II division 1 malocclusion treated using Twinblock and nine untreated patients with a similar malocclusion were included in this research. We collected their cone beam computed tomography (CBCT) data from before and 8 months after treatment. Segmentations were constructed using ITK-SNAP. Condylar volume and superficial area were measured using 3D Slicer.The 3D landmarks were identified on CBCT images by using Dolphin software to assess the condylar positional relationship. 3D models of the mandible and glenoid fossa of the patients were constructed and registered via voxel-based superimposition using 3D Slicer. Thereafter, skeletal changes could be visualized using 3DMeshMetric in any direction of the superimposition on a color-coded map. All the superimpositions were measured using the same scale on the distance color-coded map, in which red color represents overgrowth and blue color represents resorption. Results: Significant differences were observed in condylar volume, superficial area, and condylar position in bothgroups after 8 months. Compared with the control group (CG), the Twin-block group exhibited more obvious condyle-fossa modifications and joint positional changes. Moreover, on the color-coded map, more obvious condyle-fossa modifications could be observed in the posterior and superior directions in the Twin-block group than in the CG. Conclusions: We successfully established a 3D method for measuring and evaluating TMJ changes caused by Twin-block treatment. The treatment produced a larger condylar size and caused condylar positional changes. [Korean J Orthod 2020;50(2):86-97]
Effect of Global Warming on Chloride Ion Erosion Risks for Offshore RC Bridges in China
Hui-bing Xie,Yuan-Feng Wang,Jian Gong,Ming-hui Liu,Xiao-Yuan Yang 대한토목학회 2018 KSCE JOURNAL OF CIVIL ENGINEERING Vol.22 No.9
Chloride ion penetration, which leads to corrosion of steel reinforcement, is the leading cause of offshore reinforced concrete bridge deterioration. Global warming would accelerate the process of chloride ion penetration and then structural degradation. In China, durability design code for concrete structures has been issued in 2008, and some thresholds of design parameters have been specified to mitigate corrosion in concrete bridge. However, influence of global warming on structure durability was not considered in the issued code. This would overestimate the durability of concrete structures. In this paper, a reliability based method was adopted to evaluate the influence of climate change on the durability of offshore RC bridges considering the acceleration of chloride ion penetration caused by temperature rise. Two climate change scenarios according to IPCC report were considered to define the global warming. A baseline scenario, in which the mean average temperature equals to that of the year 2000, were defined. It is found that the amount of chloride ion on the surface of reinforcing steel bar in the global warming scenarios are 6%-15% higher than that of structure in the baseline scenario. Meanwhile, the probability of corrosion initiation and corrosion damage increased also. In 2100, structures in environmental categories III-C and III-F, designed according to Chinese codes, can no longer adapt the impact of climate change on structure. Comparison of reliability of improved and pre-improved structure was conducted to verify the effectiveness of the proposed improvement measures.
Numerical simulations of motion behaviors of pan mechanism in a cooking robot with granular cuisine
Yuan Chen,Zongquan Deng,Bing Liang 대한기계학회 2011 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.25 No.3
A discrete element method (DEM) model under a specific movement of wall is developed to simulate the motion behaviors of pan mechanism in a cooking robot with granular cuisine. Two performance indices describing the featured motion in Chinese cuisine are proposed to determine the main influential factors on motion behaviors. A series of simulation experiments is conducted under various conditions, and simulation results are presented to establish the relationship between the performance indices and the main influential factors. A few cuisine experiments are carried out to verify the effectiveness of these simulation results, which provide the theoretical basis and practical guideline for the design, optimization, and application of pan mechanism.
Yuan Li,Wen Liang,Bing Zhao 한국원예학회 2020 Horticulture, Environment, and Biotechnology Vol.61 No.3
Rhododendrons ( Rhododendron ) are ornamental plants that exhibit poor thermotolerance. To provide a theoretical basis forthe production and application of Rhododendron in summer, effects of high temperature and low light stress on the growth,physiological characteristics (including photosynthesis), and leaf structure of Rhododendron were explored. Two Rhododendroncultivars, Rh. ‘Fen Zhenzhu’ and Rh. ‘Zhuangyuan Hong’, were selected. Rhododendron plants were subjected tostress in 6-day intervals in an artifi cial climate box with 37.5, 75, 112.5, and 150 μmol m −2 s −1 photosynthetic photon fl uxat 38 °C. The leaf anatomical parameters and physiological indexes, including gas exchange parameters, relative water content,relative conductivity, chlorophyll and osmotic substance contents, malondialdehyde and hydrogen peroxide levels, andenzyme activity, of Rhododendron under high temperature and diff erent low light levels were measured. The results showedthat the combined stressors of high temperature and low light caused damage to leaves, such as loss of water, cell membranedamage, decreased net photosynthetic rate, and changes in leaf structure. Additionally, with the decreased light intensitycaused more damage, and diff erent damage mechanisms were found in diff erent cultivars and treatments.
Modeling and representation of a computer-aided conceptual design system
Bing Liang,Yuan Chen,Ju-Fan Zhang,Ying Hu 대한기계학회 2012 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.26 No.11
A novel hierarchical function action behavior mechanism (FABM) modeling framework is proposed to conduct intelligent mapping from the overall function to the principle solution, according to the requirements of customers. Based on the hierarchical modeling framework, an object-oriented representation method is developed to express the inheritance and the interconnecting characteristics between any two objects. In addition, the rules of expansion and modification in demand behavior are proposed to solve the combinational explosion problem, and the combinational rules in the mechanism behavior are developed to extend the innovation of the principle solution. A case study on the pan mechanism design for a cooking robot is presented to demonstrate the implementation of intelligent reasoning based on the FABM model.
Yuan, Jun-Bin,Yang, Luo-Yan,Tang, Zheng-Yan,Zu, Xiong-Bing,Qi, Lin Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.12
Although enhancer of zeste homolog 2 (EZH2) has been reported as an independent prognostic factor in renal cell carcinoma (RCC), little is known about the exact mechanism of EZH2 in promoting the genesis of RCC. However, several studies have shown that dysregulation of the Wnt/${\beta}$-catenin signaling pathway plays a crucial role. Therefore, we determined whether EZH2 could affect ACHN human RCC cell proliferation and invasion via the Wnt/${\beta}$-catenin pathway. In the present study, we investigated the effects of short interfering RNA (siRNA)-mediated EZH2 gene silencing on Wnt/${\beta}$-catenin signaling in ACHN cells. EZH2-siRNA markedly inhibited the proliferation and invasion capabilities of ACHN, while also reducing the expression of EZH2, Wnt3a and ${\beta}$-catenin. In contrast, cellular expression of GSK-$3{\beta}$ (glycogen synthase kinase-$3{\beta}$), an inhibitor of the Wnt/${\beta}$-catenin pathway, was conspicuously higher after transfection of EZH2 siRNA. These preliminary findings suggest EZH2 may promote proliferation and invasion of ACHN cells via action on the Wnt/${\beta}$-catenin signaling pathway.