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      • KCI등재

        한국 노동법의 규범력 위기

        채호일(Chae Ho Il) 한국노동연구원 2003 노동정책연구 Vol.3 No.1

        오늘날 노동법은 ‘정규직만을 보호하는 법’으로서, ‘노동귀족법’이라는 혹평을 받고 있다. 지금까지는 노동법이 ‘근로자보호’라는 하나의 도그마를 가지고, 기업내부에서 ‘노사관계’를 중심으로 구성되어 왔다. 그러나 오늘날은 노사간의 문제도 중요하지만, 정규직과 비정규직, 실업자 등 노노간의 차별과 경쟁관계도 중요한 과제로 등장하고 있다. 그러나 노동법은 그냥 속수무책으로 있다. 이것은 노동법의 규범력 상실을 의미한다. 앞으로의 노동법은 노사관계를 규율하는 ‘보호의 원리’와 노노관계를 규율하는 ‘경쟁의 원리’가 서로 조화를 이루도록 해야 한다. 노동법이 정상적인 규범력을 회복하기 위해서는 노동시장 전체의 관점에서 노사관계뿐만 아니라 근로자들 상호간의 이해관계도 공정하게 반영하는 노동법으로 다시 태어나야 한다. These days, labor law has received as much criticism as the labor-aristocracy law because it only protects full-time workers. Until now, inside companies, labor law has been formed around labor-management relations, with a dogma to protect labor. However, though the labor-management relations problem has remained important, the partiality between labor-labor relations and the competition between full-time and temporary workers (and the unemployed) has also emerged as an important issue. Yet labor law is still quite at a loss as to what to do. Essentially, this shows the loss of its normative power. In the future, labor law has to concern itself with promoting harmony between 'the principle of protection' in labor-management relations and 'the principle of competition' in regulating labor-labor relations. In order for labor law to recover its normative power, once again there must appear in the whole point of view of the labor market--not only in labor-management but also labor-labor relations--a great concern for each other.

      • KCI등재

        우골에서 추출한 골형성단백을 이용한 백서 두개골 결손부 치유에 관한 연구

        윤필(Yun Pil Chae),이종호(Jong Ho Lee),김수경(Soo Kyung Kim),여환호(Hwan Ho Yeo) 대한구강악안면외과학회 1997 대한구강악안면외과학회지 Vol.23 No.2

        Bovine BMP had been partially purified by guanidine HCI extraction and heparin affinity chromatography. It had distinct 3 bands between 20kDa and 30kDa in SDS-polyacrylamide gel electrophoresis. The critical size defect of rat calvaria, 8mm size in diameter, was used to establish osteoinductive activity of BMP and other bone graft materials. Bovine BMP plus IBM(inactivated bone matrix) as a carrier, allogenic demineralized freeze-dried bone (DFDB) and autogenous cortico-cancellous bone were implanted into the 12 rat skull defect of each group in order to evaluate repairing capacity The animals were sacrificed at the week of 2nd, 4th, 6th and 8th after operation The results were as follows 1. In the BMP-IBM complex Implantation group, the defect has been repaired completely by the 8th postoperative week. At 2 week, duster of chondroblast and cartilage appeared around the BMP-coated implant matrix. Calcification began at 6 week. At 8 week, the woven bone changed lamella bone with hematopoietic marrow and it has been bridged the both end of skull defect. 2. The repairing speed and quantity of new bone formation of BMP-IBM complex implant were superior to those of autogenous bone graft and DFDB implant. The defect which was filled with DFDB healed not only by new bone but also by retained implanted bone. The inflammatory and immune reaction of DFDB graft were more apparent than those of BMP implant and autogenous bone graft. 3. It has been assumed that the bovine BMP could be effectively used for the treatment of complicated bone defects in oral and maxillofacial region.

      • KCI등재

        Peroxisome proliferator-activated receptor γ 배위자의 간암 세포에 대한 항암 효과

        명종 ( Myung Jong Chae ),심재준 ( Jae Jun Shim ),김병호 ( Byung Ho Kim ),황보영 ( Bo Young Hwang ),이영주 ( Young Ju Lee ),하승형 ( Seung Hyung Ha ),장재영 ( Jae Young Jang ),동석호 ( Seok Ho Dong ),김효종 ( Hyo Jong Kim ),장영 대한내과학회 2008 대한내과학회지 Vol.75 No.3

        목적: PPARγ는 핵 수용체의 일종으로 혈당 조절과 지방세포의 분화에 작용하는 것뿐만 아니라 각종 암세포에 대한 항암 작용과도 연관되어 있다고 알려져 있다. 대표적인 합성 PPARγ 배위자인 thiazolidinediones계 혈당 강하제와 내인성 배위자인 15-deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2)가 간세포암(이하 간암)에도 항암 효과가 있는지 조사하였다. 방법: 간암 세포주로는 HepG2, Hep3B, PLC/PRF5를 사용하였는데, 이들 세포주에서 PPARγ 유전자 발현은 역전사-중합효소연쇄반응으로 확인하였다. Thiazolidinediones계 약물인 troglitazone (TGZ), pioglitazone (PGZ) 그리고 rosiglitazone (RGZ)을 각각 25~100 μM의 농도로 각 세포주에 투여하였고, 15d-PGJ2는 20~80 μM의 농도로 투여하였다. MTT assay를 이용하여 세포 생존률을 72시간까지 대조군과 비교하였다. 세포 주기 분석은 flow cytometry를 이용하였고, 세포자멸사는 ELISA kit를 이용하였다. Caspase-3와 caspase-8 그리고 caspase-9의 활성도를 caspase colorimetric assay를 이용하여 분석하였다. Caspase 억제제를 투여하여 PPARγ 배위자에 의한 세포자멸사가 억제되는지 조사하였다. 결과: 사용된 PPARγ 배위자 중 TGZ과 15d-PGJ2가 HepG2, Hep3B 그리고 PLC/PRF/5에 뚜렷한 성장 억제를 나타냈다. 반면에 PGZ과 RGZ은 TGZ에 비해 거의 효과가 없었다. 세포 주기분석에서도 TGZ과 15d-PGJ2가 G0/G1 arrest와 세포자멸사를 일으킨 반면 PGZ과 RGZ은 효과가 없었다. 세포 주기 및 세포자멸사 분석에서 TGZ과 15d-PGJ2의 항암효과는 세포주에 따라 서로 다르게 나타났다. TGZ은 HepG2에서 G0/G1 arrest를 일으켰고 PLC/PRF5의 세포자멸사를 유도한 반면 15d-PGJ2는 HepG2에서 세포자멸사를 일으키고 PLC/PRF5에서는 뚜렷한 세포자멸사를 일으키지 못하였다. TGZ과 15d-PGJ2은 caspase-3 활성도를 크게 증가시켰으며 (p<0.01) caspase-9의 활성도도 증가시켰다. TGZ과 15d-PGJ2에 의해 유도된 세포자멸사는 pancaspase 억제제와 caspase-3 특이 억제제에 용량 의존적으로 억제되었다. 결론: Troglitazone과 15d-PGJ2는 간암 세포에서 세포자멸사를 유도하여 항암 작용을 나타내는데, PPARγ 이외의 다른 기전이 작용하는 것으로 보이며 항암 기전도 서로 다른 것으로 생각한다. Background/Aims: Thiazolidinediones, which are synthetic insulin sensitizers, are known activators of peroxisome proliferator-activated receptor gamma (PPARγ). PPARγ ligands, including endogenous 15-deoxy-Δ12,14-prostaglandin J2(15d-PGJ2), are thought to elicit antineoplastic effects in various cancer cells. In this study, the antineoplastic effects of PPARγ ligands against hepatocellular carcinoma (HCC) cells were investigated. Methods: HepG2, Hep3B, and PLC/PRF5 cells were cultured with troglitazone (TGZ), pioglitazone (PGZ), rosiglitazone (RGZ), or 15d-PGJ2 at concentrations of 20-100 μM.. Cell viability, cell cycle arrest, apoptosis, and caspase activity were measured using the MTT assay, flow cytometry, enzyme-linked immunosorbent assay (ELISA), and colorimetric assays, respectively. The effects of various caspase inhibitors were also measured using a cell death detection ELISA. Results: All three cell lines expressed the PPARγ gene. TGZ and 15d-PGJ2 strongly inhibited growth in HepG2, Hep3B, and PLC/PRF5 cells. In contrast, PGZ and RGZ showed a much weaker effect in all cell lines. In terms of cell cycle arrest and apoptosis, TGZ induced G0/G1 arrest in HepG2 cells and increased the apoptotic fraction in Hep3B and PLC/PRF5 cells. In contrast, 15d-PGJ2 induced apoptosis only in HepG2 and Hep3B cells. TGZ and 15d-PGJ2 increased caspase-3 activity significantly and increased caspase-9 activity slightly. TGZ- and 15d-PGJ2-induced apoptoses were inhibited by a pancaspase inhibitor (Z-VAD-FMK) and a caspase-3 specific inhibitor (Z-DEVD-FMK) in a dose-dependent manner. Conclusions: TGZ and 15d-PGJ2 elicit antineoplastic effects in various HCC cells via caspase-dependent apoptotic induction. Their differential effects on similar cell types suggest that another antineoplastic mechanism, most likely a PPARγ-independent pathway, is involved. (Korean J Med 75:288-299, 2008)

      • 고추 비가림 시설에 적합한 환경관리, 재식거리 및 육묘방법 구명

        수영 ( Soo Young Chae ),박동금 ( Dong Kum Park ),이호진 ( Ho Jin Lee ),곽정호 ( Jung Ho Kwak ),이우문 ( Woo Moon Lee ),조명철 ( Myeong Cheoul Cho ),전희 ( Hee Chun ),양은영 ( Eun Young Yang ) 전북대학교 농업과학기술연구소 2014 농업생명과학연구 Vol.45 No.2

        The pepper cultivation in rain shelter greenhouses was advantageous to the increased yield and quality by preventing soil loss and infection by various pathogens. However, it also has the risk of over-growth, and flower and fruit abscission, by high temperature in the rain shelter. Beside, powdery mildew can occur due to the high-temperature and low relative humidity in the facility. This study was conducted to evaluate the proper environmental condition, nursery method and planting distance for pepper in the rain shelter. The use of mesh-net and ventilation fan increased the yield by 30% in ``Supermanitta`` cultivar in the rain shelter. The rain shelter enclosed by mesh-net increased the yield of pepper, presumably by preventing the inflow of aphids. To determine the optimum planting density of pepper plants in the rain-shelter cultivation, plants were grown in the 30, 35 and 40cm between plants. Although there was no significant difference among different planting density, the highest yield was observed in planting density of 40cm between plants. Considering the yield per unit area that is reduced by low planting density, the planting density of 35cm is appropriate for the pepper production in rain shelter. The numbers of fruits from 60, 70 and 80 day-old transplants were higher than those from 90 day-old transplants in all growth stages and no significant difference was observed among 60, 70 and 80 day-old transplants in late growth stage (100 days after transplanting). Among 32, 50, 72 and 105-cell plug trays, pepper seedlings grown in 32-cell plug trays showed highest leaf number, plant height, stem diameter, plant fresh weight and root fresh weight but these growth characteristics decreased as the number of cells increase. Seedlings from 32-cell plug trays, which showed best growth performance, bore the highest number of fruits than other cell trays. However, no difference was observed in the number of fruits in the later growth stage (100 days after transplanting) among 32, 50 and 72-cell plug trays. Considering the economic feasibility of pepper seedling nurseries, pepper seedlings grown in 72-cell plug trays for 60∼70 days may be appropriate for the pepper cultivation in rain shelters.

      • 해킹기법을 응용한 침입자역추적 시스템

        연주(Youn-Ju Chae),서진철(Jin-Cheol Seo),채호(Chae-Ho Lim),원유헌(Yoo-Hun Won) 한국정보과학회 2000 한국정보과학회 학술발표논문집 Vol.27 No.2Ⅲ

        인터넷에서 해커 등 침입자를 추적하기 위한 방안들이 연구되고 있으나 아직 실용적인 연구성과가 거의 드문 실정이다. 지금까지는 침해사고대웅팀(CERT)간의 협력과 상호 정보교류를 통한 대웅체계를 통하여 이루어지고 있으나 실제 역추적으로서는 효과적인 방법이 아니며, 에이전트를 이용한 분석 방법(AIAA)와 같은 경우도 에이전트의 수동적인 이동이 전제되어야 하는 것이다. 최근 해킹공격에 대한 적극적인 대웅 방안으로 역공격 등의 적극적인 방법들이 고려되고 자신의 시스템에 대한 보호 방법의 하나로서 받아들여지고 있는 경향이 있으므로 이러한 역공격 방법을 추적시스템에 접목하여 개량된 AIAA 모델로서 침입자 역추적방법을 설계하고 구현하였다. 여기에는 침입자 역공격 모듈과 침입자 미행모듈, AIAA 파견모듈등을 구현하여 자동적인 침입자 추적을 실현하였다.

      • KCI등재

        청력에 대한 연령과 소음 노출의 영향에 관한 5년간 청력역치 변화

        창호 ( Chang Ho Chae ),김자현 ( Ja Hyun Kim ),손준석 ( Jun Seok Son ) 한국산업보건학회 2015 한국산업보건학회지 Vol.25 No.4

        Objectives: This study was carried out to evaluate the effect of noise exposure and aging on changes in hearing threshold level and the relationship between age and noise. Materials: The author selected 274 male shipyard and assembly line workers as the noise exposed group and 582 males not exposed to noise as the general population group. Data were collected from five years of consecutive annual audiometric tests performed from 2008 to 2012. Results: In the general population and noise exposed groups, there was a reverse phenomenon that hearing threshold level for 2009 was lower than that of 2008, which seemed to be due to the learning effect, but from 2010 hearing threshold level increased. In the noise exposed group, the mean hearing threshold level in the left ear was significantly higher than that for right ear. In the general population group, the older was the age, the higher was the hearing threshold level, especially at 4000 Hz. In the general population and noise exposed groups, frequency, age group and noise exposure independently affected hearing threshold level, and there was no relationship between age and noise exposure. Over all frequencies, the change of hearing threshold level was larger in the noise exposed group than in the general population group. In the noise exposed group below thirty years old, the change at 4000 Hz was remarkable. Conclusions: Age and noise exposure seem to affect hearing threshold level independently and contribute to an additive effect on hearing threshold level.

      • 준직교 차등 시공간 변조에 대한 새로운 차등 복조 기법

        창현 ( Chang Hyeon Chae ),김준호 ( Jun Ho Kim ),김호준 ( Ho Jun Kim ),정태진 ( Tae Jin Jung ) 전남대학교 전자통신기술연구소 2009 전자통신기술논문지 Vol.12 No.1

        본 논문은 4개의 송신안테나를 사용하는 QO-STBC(quasi-orthogonal space-time block code)를 기반으로 한 준직교 DSTM(differential space-time modulation)에 대한 새로운 준직교 차등 복조 기법을 제안한다. 제안된 복조 기법은 준직교 DSTM에 대한 기존의 준직교 차등 복조 기법처럼 2개의 송신 심벌 쌍을 각각 독립적으로 복호할 수 있어 ML(maximum likelihood) 복호에 비해 수신단 복호 복잡도를 크게 낮출 수 있다. 더욱이 제안된 복조 기법은 기존의 준직교 복조 기법에 비해 고려된 모든 변조방식에서 성능 향상을 보여주며 또한 ML 복호에 비해 4-QAM에서는 거의 동일한 성능과 16-QAM에서는 약 0.5dB 이내의 성능을 보여준다. In this paper, we propose a new quasi-orthogonal differential detection method for differential space-time modulation (DSTM) based on quasi-orthogonal space-time block code (QO-STBC) with 4 transmit antennas. Because the proposed detection can independently decode two transmitted symbol pairs like conventional QO differential detection, it dramatically reduces the decoding complexity compared to maximum likelihood (ML) detection. Computer simulation results show that the proposed detection exhibits improved average error performance compared to the conventional QO differential detection and also shows almost the identical performance for 4-QAM and within 0.5dB for 16-QAM, respectively.

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