자궁근종 치료를 위한 질경유 초음파 유도하 고주파 자궁근종용해술의 장기간 효과에 대한 임상적 연구

이우석,이일한,김동호,이상훈,Lee, Woo-Seok,Lee, Il-Han,Kim, Dong-Ho,Lee, Sang-Hun 대한생식의학회 2008 Clinical and Experimental Reproductive Medicine Vol.35 No.1

목 적: 질경유 초음파 유도하 고주파 자궁근종용해술의 임상적인 효과 및 안정성에 대해 분석해 보고자 하였다. 연구방법: 2004년 12월부터 2007년 3월사이에 질경유 초음파 유도하 고주파 자궁근종용해술을 시행받은 109명을 대상으로 하였다. 환자의 평균나이는 $42.8{\pm}5.8$세였고 모두 자궁을 보존하기 원하였다. 시술 전에 이학적 검사와 초음파를 이용한 병변의 크기 측정이 이루어졌다. 추적검사는 시술 후 1주일, 1개월, 3개월, 6개월 후 시행되었으며 동일 의사에 의해 크기 및 부피변화를 측정하였고, 방문 때마다 생리과다, 생리통 등의 근종 특이증상의 호전 유무를 추적 관찰하였다. 결 과: 근종의 평균 최대직경은 $6.1{\pm}0.5\;cm$ 이었고, 고주파용해술에 소요된 시간은 평균 $16.3{\pm}8.5$분이었다. 유의 할만한 크기와 부피의 감소는 시술 1개월 이후부터 발생하였으며 근종의 평균 최대직경은 시술 후 1주일, 1개월, 3개월, 6개월에 각각 $29.9{\pm}4.8%$ (p<0.001), $41.5{\pm}1.5%$ (p=0.05), $46.2{\pm}3.9%$ (p=0.003), $54.6{\pm}6.1%$ (p<0.001)의 감소율을 보였으며 평균 부피는 각각 $44.4{\pm}8.3%$ (p=0.001), $68.1{\pm}4.2%$ (p=0.035), $73.9{\pm}4.8%$ (p=0.042), $84.5{\pm}5.1%$ (p<0.001)의 부피 감소를 보였다. 일시적인 하복통과 출혈의 지속이 각각 3명씩 있었으나 모두 교정되었고 위중한 합병증은 발생되지 않았다. 생리통과 생리과다 등의 증상은 시술 3개월 후 유의하게 감소하였다. 결 론: 질경유 고주파 자궁근종용해술은 자궁을 보존하면서 좋은 효과와 조기 회복이 가능한 안전하고 효과적인 시술법이다. Objective: This study was performed to investigate the efficacy and safety of radiofrequency (RF) myolysis under transvaginal ultrasound guidance. Methods: Transvaginal RF myolysis had been performed in one hundred nine women with uterine leiomyoma at Chung-Ang University hospital between Dec. 2004 and Mar. 2007. All patients, mean aged $42.8{\pm}5.8$ years, desired their uterine conservation. Patients underwent physical examination, transvaginal pelvic ultrasound for measurement of the lesions preoperatively. Follow up was done at 1 week, 1 month, 3 months, 6 months after RF myolysis by same physician and measurement of size and volume of myoma and improvement of myoma specific symptoms such as menorrhagia and dysmenorrhea were checked at each visit. Results: The mean maximal diameter of myomas treated by RF myolysis was $6.1{\pm}0.5\;cm$ and average time of the procedure was $16.3{\pm}8.5$ minutes. A significant decrease of myoma size and volume was observed at 1 month after myolysis. Mean reduction in maximal diameter was $29.9{\pm}4.8%$ at 1 week (p<0.001), $41.5{\pm}1.5%$ at 1 month (p=0.05), $46.2{\pm}3.9%$ at 3 months (p=0.003), $54.6{\pm}6.1%$ at 6 months (p<0.001) after RF myolysis respectively. Mean reduction in volume was $44.4{\pm}8.3%$ (p=0.001), $68.1{\pm}4.2%$ (p=0.035), 73.9$73.9{\pm}4.8%$ (p=0.042), $84.5{\pm}5.1%$ (p<0.001) at the same follow up period respectively. Significant improvement of symptom was observed at 3 months after RF myolysis. Transient low abdominal pain and prolonged vaginal bleeding were detected in 3 patients each but spontaneously resolved and no serious complication has been noticed or found. Conclusion: This study shows transvaginal RF myolysis could be a safe and effective method to treat uterine leiomyoma, allowing uterine conservation with significant volume reduction and rapid return to normal activity.

4가지 각막곡률측정 시스템을 이용한 굴절교정수술 후 인공수정체도수계산법 비교

이우석,문상정,이경헌,이동준,Woo Seok Lee,Sang Jeong Moon,Kyung Heon Lee,Dong Jun Lee 대한안과학회 2013 대한안과학회지 Vol.54 No.12

Purpose: To report the evaluation and comparison of true corneal power after corneal refractive surgery through ARK, Orbscan II<SUP>®, Pentacam and IOL master. <br /> Methods: Target IOL (Intraocular lens) power calculated with the SRK/T formula using SMK (Sungmo Eye Hospital keratometry), which is a new method for measuring corneal refractive power, was compared with the back-calculated ideal IOL power after cataract surgery for 30 eyes that required cataract surgery and had previously undergone refractive surgery. Target IOL powers calculated using 4 systems were compared with IOL power calculated using the clinical history method for 64 eyes that had undergone refractive surgery. <br /> Results: Using SMK with the SRK/T formula, the actual refraction was within ±0.5 diopter (D) of the intended refraction for 63.8% of eyes and within ±1.0 D for 90.9% of eyes. Compared with target IOL power calculated with the clinical history method, target IOL power calculated by SMK with the SRK/T formula had a difference of 1.95 ± 0.86 D, which was similar to the results calculated by the Haigis-L formula and by TNP with Haigis. <br /> Conclusions: The difference in characteristics of intraocular lenses subtly affects the vision quality as measured by values such as MTF cut-off and Strehl ratio after cataract surgery. OQAS based on the double-pass technique is considered useful in more objective estimates of the real retinal image quality after cataract surgery which is difficult to explain simply by measuring visual acuity.<br /> J Korean Ophthalmol Soc 2013;54(12):1818-1823

LDPE-나노 TiO₂ 복합 필름의 기능성 및 재질안정성 평가

이우석,고성혁,Lee, Wooseok,Ko, Seonghyuk 한국포장학회 2017 한국포장학회지 Vol.23 No.2

In this work, the effects of nano $TiO_2$ on functionality and stability of low density polyethylene (LDPE) composite films were investigated for food packaging application. LDPE-nano $TiO_2$ composite films were prepared with various $TiO_2$ contents (0, 0.5, 1.0, 3.0 and 5.0wt%) by melt-extrusion and their basic properties such as crystallinity, chemical bonds and surface morphology were examined by XRD, FTIR and SEM. Ultraviolet (UV) light barrier property of as-prepared LDPE-nano $TiO_2$ composite films was also studied and the presence of nano $TiO_2$ resulted in significant improvement of UV light barrier compared to the pure LDPE film. To evaluate influence of nano $TiO_2$ on LDPE properties required as packaging material, thermal, mechanical, gas barrier and optical properties of LDPE-nano $TiO_2$ composite films were characterized with various analytical techniques including TGA, UTM, OTR, WVTR and UV-vis spectroscopy. As a result, except optical property of LDPE, no significant effects were found in other properties. Opacity of pure LDPE was greatly increased with increasing concentration of nano $TiO_2$.

습식배연탈황공정에서 석회석의 조성이 용해속도에 미치는 영향

이우석,이형근,조항대,김인원 ( W . S . Lee,H . K . Lee,H . D . Jo,I . W . Kim ) 한국화학공학회 1995 화학공학의이론과응용 Vol.1 No.2

상안검에 국한되어 발생한 Merkel 세포 종양 1예

이우석,김상원,노주헌.Woo Seok Lee. MD. Sang Won Kim. MD. Joo Heon Roh. MD. PhD 대한안과학회 2012 대한안과학회지 Vol.53 No.6

Purpose: To report a case of Merkel cell carcinoma on the left upper eyelid without metastasis and its immunohistochemical features. The carcinoma was successfully treated with excisional surgery and prophylactic radiation therapy. Case summary: A 76-year-old woman presented to the hospital complaining of a 0.6 × 0.9-cm-sized painless and purplish- red colored mass that had grown rapidly on her left upper eyelid margin over the previous two months. An excisional biopsy was performed. On immunohistochemical examination of the lesion, the tumor cells expressed immunoreactivity for synaptophysin and were negative for LAC and cytokeratin, confirming the diagnosis of Merkel cell carcinoma. Additional surgery was performed because the surgical margins were positive. No other primary or metastatic lesions were found. The patient was treated with local prophylactic irradiation and remained disease-free at her 10-month follow-up visit. J Korean Ophthalmol Soc 2012;53(6):856-860

LDPE-나노 ZnO 복합필름의 기능성 및 재질안정성 평가

이우석,고성혁,Lee, Wooseok,Ko, Seonghyuk 한국포장학회 2018 한국포장학회지 Vol.24 No.1

In this work, nano ZnO was introduced into low density poly ethylene (LDPE) composites films with various contents (0, 0.5, 1.0, 3.0 and 5.0 wt%) by melt-extrusion. Their basic properties such as crystallinity, chemical bonds and surface morphology were examined by XRD, FTIR and SEM. XRD patterns and FTIR peaks intensity were increased in proportion to the ZnO contents. SEM images showed well dispersed nano ZnO in LDPE composite films. Antimicrobial functionality of LDPE-nano ZnO composite films was also studied and the presence of nano ZnO resulted in significant improvement of antimicrobial functionality compared to the pure LDPE film. To evaluate influence of nano ZnO on LDPE properties required as packaging material, thermal, mechanical, gas barrier and optical properties of LDPE-nano ZnO composite films were characterized with various analytical techniques including TGA, UTM, OTR, WVTR and UV-Vis spectroscopy. As a result, except optical and mechanical properties of LDPE, no significant effects were found in other properties. Opacity of pure LDPE was greatly increased with increasing concentration of nano ZnO and tensile strength was also improved at 0.5wt% ZnO content.

탄소.유황 함유량 분석장치

이우석,Lee, Woo-Seok 한국화재보험협회 2008 방재기술 Vol.45 No.-

전산화 단층 모의치료기(Computed Tomography Simulator)의 영상을 이용한 TBI(Total Body Irradiation) 자세 잡이 및 보상체 제작의 유용성에 관한 고찰

이우석,박성호,윤인하,백금문,김정만,김대섭,Lee Woo-Suk,Park Seong-Ho,Yun In-Ha,Back Geum-Mun,Kim Jeong-Man,Kim Dae-Sup 대한방사선치료학회 2005 대한방사선치료학회지 Vol.17 No.2

Purpose : We should use a computed tomography-simulator for the body measure and compensator manufacture process was practiced with TBI's positioning in process and to estimate the availability.,Materials and Methods : Patient took position that lied down. and got picture through computed tomography-simulator. This picture transmitted to Somavision and measured about body measure point on the picture. Measurement was done with skin, and used the image to use measure the image about lungs. We decided thickness of compensator through value that was measured by the image. Also, We decided and confirmed position of compensator through image. Finally, We measured dosage with TLD in the treatment department.,Results : About thickness at body measure point. we could find difference of $1{\sim}2$ cm relationship general measure and image measure. General measure and image measure of body length was seen difference of $3{\sim}4$ cm. Also, we could paint first drawing of compensator through the image. The value of dose measurement used TLD on head, neck, axilla, chest(lungs inclusion), knee region were measured by $92{\sim}98%$ and abdomen, pelvis, inquinal region, feet region were measured by $102{\sim}109%$.,Conclusion : It was useful for TBI's positioning to use an image of computed tomography-simulator in the process. There was not that is difference of body thickness measure point, but measure about length was achieved definitely. Like this, manufacture of various compensator that consider body density if use image is available. Positioning of compensator could be done exactly. and produce easily without shape of compensator is courted Positioning in the treatment department could shortened overall $15\{sim}20$ minute time. and reduce compensator manufacture time about 15 minutes.

수위-유량곡선의 보정기법 소개

이우석,Lee, U-Seok 한국수자원학회 2009 물과 미래(한국수자원학회지) Vol.42 No.7

슬관절 관절경 수술시 세척액 - 생리 식염수와 Lactated Ringer 용액의 비교

이우석,배인탁,허윤무,박원기,오병학,정환용,Lee, Woo-Suk,Bae, In-Tak,Hur, Yun-Moo,Park, Won-Ki,Oh, Byung-Hak,Chung, Whan-Yong 대한관절경학회 2008 대한관절경학회지 Vol.12 No.2

목적: 슬관절 관절경하 반월상 연골 수술 시 생리 식염수와 Lactated Ringer 용액을 세척액으로 사용하여 임상적인 결과를 분석하고자 하였다. 대상 및 방법: 내측 반월상 연골 파열로 관절경하 내측 반월상 연골 부분 절제술을 시행한 64예를 대상으로 하였다. 제 I 군은 세척액으로 생리 식염수를 사용한 군으로, 제 II 군은 세척액으로 Lactated Ringer 용액을 사용한 군으로 분류 하였다. 수술 후 1일째의 visual analogue scale, 능동적 슬관절 굴곡 각도 및 슬관절 둘레의 증가율를 측정하여 비교 분석하였다. 결과: 수술 후 1일째의 visual analogue scale 및 능동적 슬관절 굴곡 각도의 비교는 통계학적으로는 두군 간에 유의성은 없었다. 그러나 수술 후 슬관절 둘레의 증가는 Lactated Ringer 용액을 사용한 군에서 생리 식염수를 사용한 군에 비해 통계학적으로 유의하게 적었다. 결론: 슬관절 반월상 연골 수술 시 Lactated Ringer 용액이 수술 후 부종의 감소에 생리 식염수보다 좋을 것으로 사료된다. Purpose: The object of this study is to compare the clinical results of noraml saline and Lactated Ringer's solution in the arthroscopic meniscus surgery on the knee. Materials and Methods: The study group included 64 patients who had an medial meniscus tear and received arthroscopic partial medial meniscectomy. The group I was normal saline group, which was used as an irrigation solution during operation. The group II was Lactated Ringer's solution group. We measured the visual analogue scale, painless active knee flexion angle, and the ratio of the knee swelling at postoperative one day for all patients. Results: The visual analogue scale and the painless active knee flexion angle were no significant differences in comparing with normal saline and Lactated Ringer's solution group. The ratio of the knee swelling in Lactated Ringer's solution group was significantly less than those of noraml saline group. Conclusion: Lactated Ringer's solution has an advantage of decreasing the knee swelling in the arthroscopic meniscus surgery on the knee.