同軸 對向제트의 亂流特性 硏究 : 동축 대향제트의 난류특성 연구

이상수 釜山大學校 工科大學 1980 機械技術硏究所 硏究報告 Vol.2 No.-

K11 RNA 중합효소의 Cloning 및 발현

이상수,Lee, Sang-Soo 배재대학교 자연과학연구소 1997 自然科學論文集 Vol.9 No.1

PCR 방법을 이용하여 K11 RNA 중합효소를 coding하는 Klebsiella phage gene 1을 cloning 하였고 lac 전사촉진제 조절 하에 발현시켰다. K11 RNA 중합효소는 DAEA-sephacel과 Affigel blue column chromatographies를 사용하는 상용 방법으로 분리하였다. DAEA-sephacel의 0.2-0.3 M $NH_4Cl$ 분획에서 K11 RNA 중합효소의 활성을 보였고, 다음 단계의 Affigel blue column에서 SDS-polyacryl amide gel 상의 단일 band로 분리되었다. K11 RNA 중합효소는 T7 그룹 phage RNA 중합효소로 다른 T7 그룹phage RNA 중합효소와 많은 상동성을 보인다. (대장균 phage T7, T3과 Salmonella tyhimurium phage SP6 RNA 중합효소). 이미 우리는 T7과 SP6 전사촉진제 변이체를 제조한 바 있고 T7과 SP6 RNA 중합효소의 전사촉진제 특이성을 연구한 바 있다 (이상수와 강창원, 1993). K11 RNA 중합효소의 전사촉진제 특이성을 알아보기 위해 SP6 전사촉진제 변이체를 사용하여 in vitro K11 RNA 중합효소의 활성을 측정하였다. 이 변이체 중 K11 전사촉진제와 가장 유사한 것이 가장 높은 K11 RNA 중합효소 활성을 보였다. Using the PCR(polymerase chain reaction method), gone 1 of phage K11 coding for K11 phage RNA polymerase has been cloned and expressed under the control of lac promoter. K11 phage RNA polymerase was conventionally purified through the DEAE-sephacel and Affigel blue column chromatographies. The 0.2-0.3 M $NH_4Cl$ fractions of DAEA-sephacel column chromatography showed K11 phage RNA polymerase activity and further purification with Affigel blue column chromatography showed nearly single protein band on SDS-polyacryl amide gel. K11 phage RNA polymerase, which is one of the T7 group phage RNA polymerase (E. coil phage T7, T3 and Salmonella tyhimurium phage SP6 RNA polymerase), shares high degrees of homology with the other T7 group phage RNA polymerase. Previously we constructed T7 and SP6 promoter variants and revealed promoter specificity of T7 and SP6 RNA polymerase (Lee and Kang, 1993). To investigate the promoter specificity of K11 RNA polymerase in vitro K11 promoter activity was measured with SP6 promoter variants. The SP6 promoter variant share highest degrees of sequence homology with K11 promoter sequence show strongest promoter activity.

The UN’s Human Rights Policy towards North Korea: The Limit of the Neoliberal Approach

이상수 사단법인 한국평화연구학회 2012 평화학연구 Vol.13 No.2

This paper argues that North Korea needs an outside “Two-track engagement” to enhance Human Rights for its people because the regime has a systemic limit. The Democratic People’s Republic of Korea (DPRK) takes advantage of repression and violence as an instrument to secure the regime’s stability. Major North Korea’s Human Rights issues which are reflected in the UN Human Rights Resolutions are related to the Neoliberals’ way of exhortation over the matters of reunion of separated family members, abduction, food control, freedom of speech, arbitrary detention, and human trafficking etc. In North Korea, domestic societal opposition is too weak and/or too oppressed to present a significant challenge to the wayward regime. Human Rights issues can be addressed by the international community in three phases. First, establish an atmosphere through a process of adaptation and strategic bargaining, establishing a transnational Human Rights network in order to enhance North Korean Human Rights. Second, promote cooperation through a process of moral consciousness-raising, “shaming,” argumentation, dialogue, and persuasion thereby offering Human Rights education and training in order to revise ‘Our Style’’ Human Rights of North Korea. Third, develop full-scale cooperation through a process of institutionalization and habitualization, providing incentives for institutionalization of international norms for Human Rights by spreading shared values for Human Rights and mobilizing all-out support for Human Rights from member states of the international community. Political and economic incentives to North Korea can be offered if the regime tries to solve major Human Rights issues including public executions, repatriation of POWs, and elimination of torture and inhuman treatment without due process of law in correctional centers.

사법부에 바란다

이상수 한국사법행정학회 1988 사법행정 Vol.29 No.8

Vein & Office-based Surgery

이상수 대한외과학회 2019 대한외과학회 학술대회 초록집 Vol.2019 No.5

골용해에서 마모면(wear debris)에 의한 생물학적 반응

이상수,유제현,장준동 대한고관절학회 2007 Hip and Pelvis Vol.19 No.3

간세포암 환자에서 경간동맥 화학색전술후 발생한 허혈성 담도 합병증

이상수,김혜경,서동진,윤현기,이승규,정영화,이영상,양수현,성규보,이경노,황재철,유은실,송병철 대한간학회 1999 Clinical and Molecular Hepatology(대한간학회지) Vol.5 No.3

Background/Aims: Transarterial chemoembolization (TACE) has been reported to be one of the useful palliative treatments in patients with unresectable hepatocelluar carcinoma. However, Bile duct injuries following TACE have been reported occasionally. In this study, we intended to clarify the incidence, pathogenic mechanisms and clinical implications of bile duct injuries following TACE. Methods: A total of 950 consecutive patients with hepatocellular carcinoma (HCC) were subjected. 807 patients were treated with TACE. The remaining 143 were treated with transarterial chemoinfusion (TACI) of cisplatin. Results: None of 143 HCC patients treated with TACI revealed to have any ischemic biliary injury radiologically. In contrast, out of 807 with TACE, 17 (2%) appeared to have biliary complications. Twelve out of 17 (71%) had bilomas at subcapsular area, three out of 17 (18%) had focal strictures at common hepatic duct or common bile duct with marked dilatation of intrahepatic bile ducts and two out of 17 (11%) had diffuse mild dilatation of intrahepatic bile ducts. Interestingly, two (17%) out of 12 bilomas were found at the lobe which was not embolized with Gelfoam. The median sessions of TACE to the occurrences of focal strictures tended to be longer compared with those of bilomas (median: 6 vs. 2.5; p=0.08). All three patients with focal strictures and four (33%) out of 12 patients with bilomas were associated with serious bacterial infections at presentation. Conclusions: Biloma seems to be caused by lipiodol rather than Gelfoam; focal strictures of large bile ducts by Gelfoam. It is suggested that adjustments of the amounts of lipiodol or Gelfoam and the sites or embolization may be required to reduce the ischemic biliary injuries following TACE. (Korean J Hepatol 1999;5:217-226)

考古資料를 통해 본 悉直國

이상수 한국이사부학회 2014 이사부와 동해 Vol.8 No.-

강원 동해안지역에 존재했던 고대 정치세력의 대표적인 집단은 濊國과 悉直國으로서, 이들은 濊[東濊]계의 일원으로 파악되고 있다. 지금까지 실직국에 대한 연구는 문헌사적, 역사고고학적, 순수고고학적 측면에서 다양하게 이루어졌다. 그러나 실직국의 실체에 대한 보다 구체적이고 합리적 이해는 현재 충분하지 않다. 본 연구는 삼척·동해지역으로 공간적 범위를 제한하여 최근까지 조사된 철기시대 유적·유물을 검토하여 실직국의 문화 양상과 그 변천과정의 일면을 살펴보았다. 실직국 관련 철기시대 유적들은 영동지방에서와 같이 해안사구지대에 입지하는 呂자형·凸자형 주거지와 중도식토기를 공반하고 있어, 소위 中島類型文化를 공유하는 동예와 동일한 문화권에 속하는 것으로 파악된다. 실직국 관련 철기시대 주거지들은 대체로 呂자형·凸자형 주거지가 시기적으로 선행하고, (장)방형계 주거지가 후행하는 양상을 보이지만, 일부 凸자형 주거지와 (장)방형계 주거지가 늦은 시기까지 함께 공존하는 양상도 파악된다. 실직국 관련 유적 중, 동해 송정동유적은 지금까지 영동지방에서 최대 규모의 마을유적으로 확인된 점, 최고의 위계를 상징하는 유물과 주변지역(한군현, 진한, 변한, 마한 등)과의 활발한 대외교섭 행위를 시사하는 외래적인 유물들이 다수 출토된 점, 철기생산과 직접 관련된 공방지가 존재하는 점 등에서 실직국과 관련된 강력한 집단세력이 거주했던 것으로 이해된다. 실직국의 장례문화는 종족상으로 보아 옥저와 같은 가족장을 위한 지상식 대형목곽묘를 공유했을 것으로 추정되어, 오늘날까지 지상에 남아 있을 가능성은 매우 희박한 것으로 이해된다. 실직국에 거주했던 예의 종족들이 남긴 물질문화를 통해서, 실직국은 적어도 기원 1세기부터 기원 4세기 무렵까지 동예사회의 공통적인 물질문화를 유지하였으며, 한군현과 진변한 등 주변 세력과의 대외관계를 통해 선진문물을 적극 수용했던 것으로 이해된다. 최근까지 확인된 실직국 관련 고고자료를 통해서, 실직국은 대체로 강릉의 예국사회와 같이 대동소이한 문화변동의 단계를 거쳐 전통문화가 점차 해체되면서, 신라와의 밀접한 관계 속에서 신라화 과정을 겪었던 것으로 추정된다. 이러한 과정에서 실직국은 적어도 4세기 후반 또는 5세기 초에 신라문물이 유입되고 확산되면서 이후 토착문화를 대신하여 신라 영역화에 따른 신라문화권으로 완전히 변화되었던 것으로 이해된다. Yaeguk and Shiljikguk are the representative groups of political power that existed in eastern coast of Gangwon during ancient times. These groups seem to come from Yae (Dongyae). Up to date, various studies have been performed on Shiljikguk from the perspectives of literature, historical archaeology, and pure archaeology. However, detailed and rational understanding concerning the true identity of Shiljikguk is not sufficient at present. This study reviewed the relics and remains of the Iron Age that were investigated until recently by limiting the spatial cope to the areas of Samcheok and Donghae (eastern coast), and examined the culture as well as transition process of Shiljikguk. The remains of the Iron Age related to Shiljikguk include earthenware of Joongdo type as well as dwelling of 呂 shape and 凸 shape that can be found in the area of Coastal Dune that are similar to the area of Yongdong. This leads to assume that it belongs to the same cultural area as Dongyae that shares "Joongdo type culture). Dwellings related to Shiljikguk of the Iron Age shows a pattern of which 呂 shape and 凸 shape dwellings precede, followed by rectangular shape in general, but in certain cases, both types of 凸 and rectangular dwellings appear to have coexisted until the late period. The facts that the remains of Songjeongdong, Donghae were found to be the largest village remain in Yeongdong area until now among the remains related to Shiljikguk, that relics symbolizing the highest hierarchy as well as various foreign relics have been excavated demonstrating active foreign trade activities with surrounding areas (Hangunhyeon, Jinhan, Byeonhan, Mahan, etc.), and that workshop site related to iron production existed, all lead to the conclusion that powerful group related to Shiljikguk resided. Taking the characteristics of tribe, funeral culture of Shiljikguk appears to have consisted of large wooden chamber tomb on the ground for family like Okjeo, and it is unlikely that it still remains at present. From the culture left by the tribe of Yae who resided in Shiljikguk, it can be understood that Shiljikguk maintained material culture common to Dongyae at least from 1st to 4th century, and that Shiljikguk actively accepted advanced culture through foreign relationship with surrounding powers such as Hangunhyeon, Jinhan and Byeonhan, etc.Through the recent archaeological evidences, it can be assumed that traditional culture Shiljikguk disappeared gradually through cultural change identical to Yaeguk society of Gangneung, and experienced of becoming like Shilla through close relationship with Shilla. Through such process, Shiljikguk seems to have become absorbed completely to Shilla culture instead of maintaining traditional culture since Shilla culture came in and expanded at least in the late 4th century or early 5th century.

A New Option for Development of Human Security in East Asia: Reforming the ASEAN Regional Forum

이상수 사단법인 한국평화연구학회 2011 평화학연구 Vol.12 No.2

This paper argues that a reformed ASEAN Regional Forum (ARF) can promote human security in East Asia. The promotion of ARF-centered human security requires a definition that accords with the respective cultures and values of its member states. The sources of human insecurity that plague the region include: the proliferation of weapons of mass destruction (WMD), terrorism, traffickingin illicit drugs, persons, and arms, North Korean ‘famine refugees,’ health insecurity, HIV/epidemics, , various forms of economic crime, environmental insecurity, domestic threats, political insecurity, ethnopolitical conflict, poverty and economic inequity, food security, acid rain, and yellow dust. Human security issues can be addressed in the ARF by three phases. First, Establishing atmosphere: Creating norms for human security in East Asia, and Establishing a human security academy or research center. Second, promoting cooperation: Establishing an independent secretariat at ARF, creating a human security promotion center under the secretariat, raising funds for human security, cultivating human security culture through education. Third, Full-scale cooperation: Spreading shared values for human security and mobilizing all-out support for human security from member states are prerequisite to promoting human security in East Asia.Even though ARF member states have different ideas and interpretations of human security, their enhanced cooperation and openness may improve the human security situation in East Asian region

10Gbps 신호의 아이 마진 특성 ( Eye Margin Characteristics of 10Gb/s Signal )

이상수,한정희,김민규,이동호,주무정 한국통신학회 1998 한국통신학회 기타 간행물 Vol.- No.-