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이경근(Kyoung Keun Lee),안해선(Hae Sun Ahn),이광만(Kwang Man Lee) 대한두경부종양학회 2000 대한두경부 종양학회지 Vol.16 No.1
Thyroglossal duct cyst is common midline mass, which is related to hyoid bone and may show signs of inflammation. Carcinoma arising in the thyroglossal duct cyst is rare, occuring in less than 1% of thyroglossal duct cyst. Papillary adenocarcinoma is the most common histologic type(75-85%). The initial treatement of choice is wide excision of the tumor bearing tissue(Sistrunk procedure), resection of associated lymph node alone is enough when they are small and isolated, but a modified neck dissection must be done if regional involvement is more extensive. Its prognosis is excellent(the incidence of regional lymph node metastasis is 7% compare to 89% for papillary cancer of thyroid gland proper).
재생형 블로워에서 발생하는 비정상 유동과 유동 소음 특성에 관한 연구
전완호(Wan-Ho Jeon),임태균(Tae-Gyun Lim),이경근(Kyoung-Keun Lee),장춘만(Choon-Man Jang),이상문(Sang-Moon Lee) 한국소음진동공학회 2015 한국소음진동공학회 학술대회논문집 Vol.2015 No.4
This paper shows the characteristics of the unsteady flow field and aeroacoustic noise of a regenerative blower. Three-dimensional Navier-Stokes equations were applied as a numerical solution to analyze the unsteady flow field with static pressure fluctuation on the impeller and an the casing. For computational study, it was predicted that the upper part of outlet region and the tips of blades are dominant aeroacoustic noise sources in the regenerative blower. The measurement data of sound camera indicates that the dominant noise source of the regenerative blower appears in the outlet region. In this study, the position of noise source and the characteristic of noise by using numerical solution were predicted and validated through comparison between experimental data and computational ones. It is represented as fundamental data which are able to be used to reduce the noise in a regenerative blower.
이정균,이경근,안진홍 圓光大學校 醫科學硏究所 1999 圓光醫科學 Vol.15 No.2
Background: In 1983, Warren and Marshall presented the evidence that H. pylori was associated with gastritis and peptic ulcer. Thereafter, H. pylori infection is thought to be a important factor in the pathogenesis of gastric cancer and peptic ulcer. The aim of study was to investigate the relationships between CLO positivity and clinico-pathologic features in gastic cancers and peptic ulcer which was surgically resected. Methods: Retrospective clinics-pathologic study was performed in 80 patients from 1998 to 1999. We performed the CLO tests in 63 patients with resected gastric cancer. Biopsy was done in 17 operative patients with peptic ulcer. Two specimens was taken from body and antrum of stomach. Results: 1) The CLO positivity was 63.5% in resected gastric cancers and 64.7% in peptic ulcer which biopsy was done among the operation. But, there was no significant difference between two groups. 2) There was no significant difference of clinical features and CLO positivity in gastric cancers groups. 3) There was no significant difference of TNM classification and stage in CLO(+)(-)patients in gastric cancers group. 4) There was no significant difference of clinical features and CLO positivity in peptic ulcer groups. Conclusions: The positive CLO tests was 64.7% in gastric ulcer, 87.5% in duodenal ulcer, and 63.5% in stomach cancer. There was no difference of CLO positive ratio in stomach cancer and peptic ulcer. There was no clinico-pathologic difference between CLO(+) and (-) gastric cancer.
화상을 입은 백서에서 식이의 성분이 세균전위에 미친 영향
이광만,이경근,조지현 圓光大學校 醫科學硏究所 1997 圓光醫科學 Vol.13 No.1-2
Bacterial translocation means the passage of viable bacteria from the gastrointestinal tract to normally sterile tissues such as the mesenteric lymph nodes and other internal organs. It is now clear that translocation is increased in bums and in injury including hemorrhagic shock. Total parenteral nutrition and elemental enteral diets are thought to be associated with atrophy of the intestinal mucosa and increased translocation. The purpose of this study was to determine whether or not the composition of nutrients effects on bacterial translocation in normal and burned rats. 54 male Sprague-Dawley rats were randomized to 3 groups of 18 animals each. Group Ⅰ was non-burned control rats, and group Ⅱ and Ⅲ were burned rats. Rats in group Ⅱ and Ⅲ were subjected to contact dermal bum of 10% and 20% each of their body surface area. All 3 groups were re-randomized to 3 subgroups of 6 animals each; subgroup 1 fed rat chow, subgroup 2 fed elemental diet(Energen®) and subgroup 3 fed oral TPN solution. Animals were fed respective diets ad libitum for 2 weeks, and then mesenteric lymph nodes, portal vein blood, and cecal content were aseptically obtained for culture. Bacterial count in mesenteric lymph nodes(MLN) of burned rats was significantly increased than that of non-burned rats(p=0.033). In burned rats, MLN bacterial count was the highest in the rats fed oral TPN (566.1±870.5/g vs. 270.1±382.4/g in the rats fed elemental diet and 164.9±184.7/g in the rats fed chow). Cecal culture in burned rats revealed a statistically significant increase in the cecal anaerobic count in the rats fed oral TPN when compared to the rats fed chow or elemental diet(p=0.003). There was close correlation between MLN bacterial count and cecal aerobes count(r=0.843, p=0.001). In conclusion, the type of nutrients had influence on bacterial translocation in burned animals partly by increasing the cecal bacterial population.
안진홍,이정균,이경근 圓光大學校 醫科學硏究所 1999 圓光醫科學 Vol.15 No.2
Primary retroperitoneal mucinous cystic tumors are very rare. In the world wide literature, only 20 cases have been reported. We report a case of retroperitoneal mucinous tumor found at laparotomy. The mass was uniloculated and 20×20 ㎝ in size. Pathologically examination revealed a mucinous cystadenoma with borderline malignancy, low grade. Preoperative diagnosis in patient was ovarian carcinoma based on clinical and computerized tomography findings. Similar previously reported cases and their possible pathogenetic mechanisms are discussed.
건 황색종의 가족력과 관상동맥질환을 갖는 이형집합 가족성 고 콜리스테롤혈증 1례
백승훈,형근영,김경년,조정구,이경근 圓光大學校 醫科學硏究所 1997 圓光醫科學 Vol.13 No.1-2
Familial hypercholesterolemia is a common autosomal dominant disorder with serious health consequences such as the coronary heart disease, in western area affecting approximately 1 in 500 persons in the heterozygous form, is caused by a mutation in the gene for the LDL(low density lipoprotein) receptor. A-45-years old male came to the hospital because of tendon xanthomas on both elbows, knees, and ankles. He also has retrosternal chest pain intermittently since 5 years ago. 4 kindreds of the patient have tendon xanthomas according to autosomal dominant inheritance. Serum levels of total cholesterol and triglyceride were 359 ㎎/dL, 103 ㎎/dL respectively. Lipoprotein electrophoresis showed type Ⅱa pattern. Treadmill exercise test revealed angina pectoris. The case of familial hypercholesterolemia who has familial inheritance of tendon xanthoma is rarely reported in Korea. We report this case with a review of the related literature