방사선과 폐수산자원을 이용한 하수 농축슬러지 처리에 관한 연구

유대현,이재광,이면주,강호,Yoo Dae-Hyun,Lee Jae-Kwang,Lee Myun-Joo,Kang Ho 한국자원리싸이클링학회 2004 資源 리싸이클링 Vol.13 No.4

본 연구는 하수처리장에서 발생되는 농축슬러지의 처리방법에 대해 진행하였다. 방사선을 15 kGy 조사하였을 때 농축슬러지에 존재하는 일반세균 및 대장균을 99% 이상 제거, 유기물 분해등 소화조에서 일어나는 공정을 대체 할 수 있다. 폐수산자원인 불가사리를 가공하여 제조한 물리개량제를 첨가하여 응집공정의 효율을 높이고 아울러 함수율 10% 이상의 저감효과를 얻을 수 있다. This study was focused on the treatment of thickened sewage sludge. General bacteria and E. coli were disinfected over 99% and organic compounds were decomposed after irradiation. It was suggested that this process can be an alternative for digestion Process. The moisture content in sludge was decreased over 10% (w/w) and the coagulation of sludge particles was enhanced by irradiation at the dose of 15 kGy and addition of sea waste resource (star-fish) as a dewatering aid.

하이개부에 발생한 모기질종

유대현,최문기,오승환,권대근,전인철,손도경,박성원,Yoo, Dae-Hyun,Choi, Moon-Ki,Oh, Seung-Hwan,Kwon, Dae-Keun,Jun, In-Chul,Son, Do-Kyoung,Park, Sung-Won 대한악안면성형재건외과학회 2010 Maxillofacial Plastic Reconstructive Surgery Vol.32 No.6

Pilomatricoma or calcifying epithelioma is a benign tumor of hair follicle origin. Pilomatricoma presents a slowly enlarged and asymptomatic mass that located dermal or subdermal area. It showed mostly on face and upper limb and head and neck represents 50% of all case. And it developed almostly in the first 2 decade of life. Histologically, encapsulated mass composed of solid small basophilic cells and eosinophilic ghost cells. Surgical excision is the treatment choice and rarely recurs. The purpose of this article is to represent of pilomatricoma on subauricular region that treated with mass excision and local transpositional flap. Althrough the presurgical diagnosis of pilomatricoma may be difficult, clinicians must keep in mind the differential of head and neck masses that located subdermal layers.

류마토이드 관절염에 대한 Thymopentin 의 치료효과에 관한 임상적 연구

유대현(Dae Hyun Yoo),배상철(Sang Cheol Bae),박찬현(Chan Hyun Park),김성윤(Seong Yoon Kim) 대한내과학회 1991 대한내과학회지 Vol.41 No.4

N/A Thymopentin is a synthetic pentapeptide corresponding to residues of 32-36 of the parent thymic hormone, thymopoietin, and has been shown to have some immunomodulating actions, especially on T lymphocytes. Thymopentin was used in the treatment of rheumatoid arthritis, and its clinical efficacy was noted by a few investigators. We experienced the antirheumatic effect and side reaction of thymopentin in 20 patients with active rheumatoid arthritis. The results were as follow; 1) Eleven out of the 20patients studied were classified as responders. 2) With thymopentin treatment, clinical rheumatic activity improved moderately in 2patients, minimally in 9patients, uchanged in 7patients, and worsened in 2patients. 3) ESR was changed after the 10th and 12th week but not changed during thymopentin therapy. 4) The Ritchie articular index, swollen joint score, the number of painful joints on motion and rest, and the patients self-assessment of pain improved between the 6th and 8th week, but the grip strength of both hands and the duration of morining stiffness were not changed significantly. 5) Side reactions were found in only 3 patients and eliminated without specific medical intervention. In summary, thymopentin could be administered without serious side effects for 8weeks. Although the clinical effect was noted after 6weeks of treatment, the antirheumatic effect of thymopentin was not significant. It may be necessary to conduct further studies regarding a more simple method of administration, combination therapy with conventianal I)MARD, and maintenance therapy of thympentin.

직류출력과 교류출력을 갖는 단상 Z-소스 전자변압기

유대현(Dae-Hyun Yoo),엄준현(Jun-Hyun Eom),정영국(Young-Gook Jung),임영철(Young-Cheol Lim) 전력전자학회 2013 전력전자학술대회 논문집 Vol.2013 No.11

류마티스 관절염과 퇴행성 관절염의 활액막조직에서 VLA 항원의 발현에 관한 연구

유대현(Dae Hyun Yoo),정성수(Sung Soo Jung),이인홍(In Hong Lee),배상철(Sang Cheol Bae),김성윤(Seong Yoon Kim),김목현(Mok Hyun Kim),정현기(Hyun Kee Chung),최일용(Il Yong Choi) 대한내과학회 1994 대한내과학회지 Vol.46 No.5

N/A Objective: The adhesion molecule that mediate cell-cell and cell-extracellular matrix provides very important role in various physiologic and pathologic conditions, VLA integrin is heterodimeric transmembrane glycoprotein which participate in cell-cell and cell-extracellular matrix, especially collagen, laminin and fibronectin. Rheumatoid arthritis is important prototype of chronic inflammatory disease. Continuous emigration and anchorage of chronic inflammatory cells are prerequisite for the perpetuation of disease. Transient episode of inflammatory synovitis could be found in osteoarthritis also. Although the notion that VLA-integrin play a major role in the initiation and perpetuation of arthritis would be possible, distribution of VLA integrin in synovial tissue of rheumatoid arthritis and osteoarthritis was investigated by immunohistochemistry. Methods: Immunohistochemical analysis of synovial tissue utilizing avidin-biotin complex method was con- ducted. Applied monoclonal antibodies were CD49a-f, CD29, CD51, and CD61. The pattern of expression was scored by semiquantitative grading system. Results: 1) The expression of CD29 was diffuse and intense at synovial lining cells, endothelium and infiltrating inflammatory cells. Endothelial stain was evident with VLA-1, 6, CD51 and negative with VLA-4. Inflammatory cells expressed VLA-4, 5 intesively and synoviocytes expressed VLA-3, 5, 6 and CD51 as ligand for fibronectin and laminin. 2) CD29 expression of inflammatory cells were prominent around small blood vessles which showed strong stain of CD29 and located just beneath the synovial lining cells. 3) VLA-integrin expression in synvoium of osteoarthritis was smimilar to that of rheumatoid arthritis except little inflammatory cell infiltratilon and little proliferation of microvasculature. Conclusion: It was able to presume from above findings that VLA-integrin has been doing some role in the development and perpetuation of synovitis. Future perspectives in field of VLA-integrin may be exact process of intracellular signalling, functional aspect of integrin and regulation of expression by some cytokines and growth factors.

다발성 폐결절로 나타난 Behcet 씨병의 폐동맥염 1 예

유대현(Dae Hyun Yoo),정성수(Sung Soo Jung),최영춘(Young Chun Choi),이진(Jin Lee),안종훈(Jong Hoon Ahn),김성윤(Seong Yoon Kim),박성수(Sung Soo Park),이정희(Jung Hee Lee) 대한내과학회 1989 대한내과학회지 Vol.36 No.5

N/A Behcet's disease is known as a multisystemic disease caused by nonspecific vasculitis of obscure origin. Among the systemic manifestations, pulmonary involvement is know to be very rare and only a few cases have been documented. The most important features of pulmonary lesions in Behcet's disease are the fleeting nature of the pulmonary infiltrate and recurrent hemoptysis, which is often massive and fatal. We report a case of Behcet's disease manifested as multiple pulmonary nodules which was caused by pulmonary infarction as a result of pulmonary arteritis.

γ-ray 조사를 통한 하수처리장 배출수내 미생물살균에 관한 연구

유대현(Dae Hyun Yoo),박상욱(Sang Wook Park),정영도(Young Do Jung),김종배(Jong Bae Kim),이면주(Myun Joo Lee),강준원(Joon Wun Kang) 大韓環境工學會 1999 대한환경공학회지 Vol.21 No.4

Hadoop 기반 분산 컴퓨팅 환경에서 네트워크 I/O의 성능개선을 위한 TIPC의 적용과 분석

유대현(Dae Hyun Yoo),정상화(Sang Hwa Chung),김태훈(Tae Hun Kim) 한국정보과학회 2009 정보과학회논문지 : 시스템 및 이론 Vol.36 No.5

Recently with increase of data in the Internet, platform technologies that can process huge data effectively such as Google platform and Hadoop are regarded as worthy of notice. In this kind of platform, there exist network I/O overheads to send task outputs due to the MapReduce operation which is a programming model to support parallel computation in the large cluster system. In this paper, we suggest applying of TIPC (Transparent Inter-Process Communication) protocol for reducing network I/O overheads and increasing network performance in the distributed computing environments. TIPC has a lightweight protocol stack and it spends relatively less CPU time than TCP because of its simple connection establishment and logical addressing. In this paper, we analyze main features of the Hadoop-based distributed computing system, and we build an experimental model which can be used for experiments to compare the performance of various protocols. In the experimental result, TIPC has a higher bandwidth and lower CPU overheads than other protocols. 최근 인터넷 서비스 기반의 데이터는 대용량화되고 있으며 대용량 데이터를 효과적으로 처리할 수 있는 구글 플랫폼, Apache Hadoop과 같은 플랫폼 기술이 각광받고 있다. 이러한 플랫폼에서는 분산 프로그래밍을 위한 기법으로 MapReduce가 수행되며, 이 과정에서 각 태스크의 결과를 전달하기 위한 네트워크 I/O의 부하 문제가 발생한다. 본 논문에서는 구글 플랫폼, Hadoop과 같은 대규모 PC 클러스터 상의 분산 컴퓨팅 환경에서 네트워킹 부하를 경감하고 성능을 향상시키는 방안으로 TIPC(Transparent Inter-Process Communication)의 적용을 제안한다. TIPC는 경량화된 연결설정 및 스택 크기, 계층적 주소체계로 인해 TCP보다 가볍고 CPU 부하가 적은 장점을 가지고 있다. 본 논문에서는 Hadoop 기반 분산컴퓨팅 환경의 특징을 분석하여 그와 유사한 실험환경을 모델화하고 다양한 프로토콜의 비교실험을 수행하였다. 실험결과 평균 전송률에서 CUBIC-TCP, SCTP와 비교해 TIPC의 성능이 가장 우수하였으며, TIPC는 CPU 점유율 측면에서 TCP와 비교해 최대 15%의 낮은 CPU 점유율을 보였다.

전신성 홍반성 루푸스와 Apoptosis

유대현 ( Dae Hyun Yoo ) 대한류마티스학회 1997 대한류마티스학회지 Vol.4 No.1

Systemic lupus erythematosus is a prototype of systemic autoimmune disease which is characterized by polyclonal B cell activation and production of various autoantibodies, especially antibodies against nucleosome. The pathogenesis of lupus does not depend on a single gene defect but depend on multiple genetic and environmental factors. Lately defects of apoptosis have been focused as a potential etiologic factor of systemic autoimmune diasease. Apoptosis is an active programmed cell death which removes unwanted cells without any inflammatory sequelae. Cells of immune system are programmed to be deleted unless recruited into appropriate immune response. The fate of certain cell may be controlled by the balance between cell death signals and survival signals for each cells. The importance of these pathways in maintaining tolerance is highlighted by the development of lupus-like disease in three different mouse strains that have spontaneous mutations in the Fas or its ligand. We have a lot of reports on the relationship between apoptosis and systemic lupus erythematosus in terms of pathogenesis after then. We need to review all information on apoptosis and lupus and find appropriate direction toward research and clinical aspect, even though we don`t have complete knowledge on signal transduction and regulators of apoptosis. Here relationships between systemic lupus erythematosus and apoptosis were reviewed on a few different viewpoints: 1) too little apoptosis of immune cell, 2) accelerated spontaneous apoptosis and nucleosome secretion, 3) defective phagocytosis of macrophage, 4) relationship between antiphospholipid antibody and apoptosis.

연골표면에 침착한 면역물질의 양상에 관한 연구

유대현(Dae Hyun Yoo),정성수(Sung Soo Jung),이인홍(In Hong Lee),배상철(Sang Cheol Bae),김성윤(Seong Yoon Kim),김신규(Think You Kim),정현기(Hyun Kee Chung),최일용(Il Yong Choi) 대한내과학회 1993 대한내과학회지 Vol.45 No.6

N/A Background: Immune deposits were found on the articular surface of rheumatoid arthritis and osteoarthritis even though the prevalence and pattern of immune deposits were differnt between rheumatoid arthritis and osteoarthritis. Authors conducted this study to compare the pattern and positive rate of immune deposits on surface of articular cartilage between rheumatoid arhtritis and osteorthritis. Methods: Articular cartilages were obtained from patients who were conducted total joint replacement surgery at knee or hip joint. Selected cases were 15cases of rheumatoid arthritis, 45cases of osteoarthritis. Immune deposits were searched using direct immunofluorescent technique with FITC conjugated anti-IgG, IgA, IgM, C, antibody. Results: 1) Positive rate of immune deposits on articular cartilage was 66.7% in rheumatoid arthrtis and 26.7% in osteoarthritis. 2) Granular staining pattern was found in only 6patients out of 10positive patients with rheumatoid arthritis. In osteoarthritis, the pattern of immune deposits was not granular but nongranular pattern such as intermittent linear or linear pattern. 3) Positive rate in primary osteoarthrits and secondary arthritis was 32%, and 26.7% respectively. 4) Rheumatoid factor was reactive not only in 6cases with granular pattern but also in 3cases without immune deposits and in 2cases with nongranular pattern. Coclusion: Immune deposits was found more frequently in rheumatoid arthritis than osteoarthritis and granular pattern was noted in cases with rheumatoid arthritis only. The differences in prevalence and pattern of immune deposits between rheumatoid arthritis and osteoarthritis may be due t different antigen, mechanism of immune deposition or another unknown factors. Further investigation have to be conducted in these respects.