질산용액에서 Nitroaniline 류에 의한 Al-brass의 부식억제에 관한 연구

주석복,김면섭,이성하 漢陽大學校 環境科學硏究所 1992 環境科學論文集 Vol.13 No.-

0.1M 질산용액에서 nitroaniline류에 의한 Al-brass의 부식억제에 대하여 무게감량 실험, 분극실험, SEM사진 분석 등을 행하였다. Al-brass의 부식속도는 부식계의 온도와 억제제의 농도 그리고 부식억제제의 형태 등에 의존한다. 무게갈량실험과 분극실험을 통해 알아낸 부식억제 효율은 2-nitroaniline>3-nitroaniline>4-nitroaniline의 순이었다. 분극실험의 결과로부터 억제제의 농도가 증가할수록 부식전위는 noble한 방향으로 이동하며 양극 Rafel slope는 일정한 반면 음극 Tafel slope는 증가하여 전류밀도를 감소시키는 것으로 보아 억제제인 nitroaniline는 Al-brass의 음극반응을 억제하는 것을 알 수 있었다. SEM사진 분석에서는 Al-brass의 표면상태를 확인함으로써 각 억제제가 부식반응을 상당히 억제하고 있음을 알 수 있었다. 또한, Flory-Huggins adsorption isotherm의 도입으로 구한 열역학적 특성치로부터 억제제의 흡착형태 등을 알 수 있었다. The inhibition effect of nitroanilines of corrosion of Al-brass in 0.1M nitric acid has been studied by weight loss measurement, polarization method and scanning electron microphotographs. Corrosion rate of Al-brass was depended on concentration of inhibitor and and temperature. The order of inhibitor efficiency according to the position of the substitued group was 2-nitroaniline>3-nitroaniline>4-nitroaniline. The results obtained from weight loss measurements were agreed to those obtaind from polarization studies. Thermodynamic parameters obtained form Flory-Huggins adsorption isotherm showed strong interaction between inhibitor molecules and Al-brass surface.

전자선과 불가사리 분말을 이용한 하수슬러지 탈수능 향상

유대현,이재광,이면주 한국환경과학회 2004 한국환경과학회지 Vol.13 No.7

This study was focused on the manufacturing method of a dewatering aid, which would reduce the water content of the sludge cake by enhancing the dewaterability of sewage sludge. The pretreatment technology for sludge by using radiation and among diverse discarded resources were starfish selected as the material to manufacture the dewatering aid. Starfish went through the process of washing, drying, and pulverizing. The starfish powder made in this process was applied to the digested sludge generated at the sewage treatment plant of D City, and its effects were investigated. The starfish powder that was 300 ㎛ in particle size was added to the irradiated digested sludge. After the application of the condensation process, the sludge with the starfish powder added was dewatered using the belt press and centrifuge, which were the traditional pressure dewatering devices. As the result, it reduced the water content of the sludge 20% higher than the dewatered cake with no dewatering aid added and irradiation. When the powder was added, it contributed to less use of the coagulant added. The more irradiation dose, the lower water content did the dewatered cake have and the more coagulant was needed for condensation, which seems to be a disadvantage that can be compensated for by the starfish dewatering aid. A small-scaled treatment of the study to a radiation technology and dewatering aid using a discarded resource confirmed the potential of dewaterability. Based on the results saying that the dewatering aid and radiation technology can improve dewatering effects using the traditional dewatering devices, this pretreatment technology will be expected to be applied to sewage treatment plants.

추간판 응력분포에 대한 광탄성 해석

신현국,이재창,안면환,안종철,인주철 영남대학교 의과대학 1989 Yeungnam University Journal of Medicine Vol.6 No.2

요추의 중립위, 굴곡위 및 신전위에서의 응력 분포의 차이와 수핵의 유무에 따른 응력 분포의 변화를 관찰하기 위해 본 연구를 시행 하였으며 등색선의 양상을 관찰하고 그 응력을 해석하여 다음과 같은 결론을 얻었다. 1. 기립 중립위에서는 수핵이 있는 경우는 전방 부위보다 후방부위에 고응력이 집중되었으며, 전후방 모두 내측부와 중간부위가 고응력이고 외측부로 이동할수록 적응력이 관찰되었다. 수핵이 없는 경우는 후방보다 전방부에 고응력이 집중되었으며 국소적으로 응력이 집중되는 양상을 보이고 있다. 2. 최대 굴곡위에서는 수핵의 존재에 관계없이, 전방보다 후방부에 고응력이 집중되었으며, 수핵 유무 비교시 수핵이 있는 경우가 없는 경우보다 전방이 저응력, 후방은 거의 동등한 응력 분포를 나타냈었다. 응력 분포도의 분석에 의하면 전반적으로 균등한 응력 분포 양상을 나타냈다. 3. 최대 신전위에서는 수핵 유무에 관계없이 전방부에 고응력, 후방부에 저응력, 내측에 고응력, 외측은 저응력을 나타내었으며, 수핵이 있는 경우 없는 경우보다 고응력을 나타냈다. 4. 기립 중립위와 최대 굴곡위의 비교에서는 기립 중립위보다 굴곡시 수핵의 유무에 관계없이 전반적으로 후방부 응력이 2차 정도 현저히 감소하는 양상을 보이면서 비교적 균등한 응력 분포를 나타냈다. 5. 최대 신전위와 최대 굴곡위의 비교에서는 수핵 존재시 최대 신전위보다 최대 굴곡위에서 응력 분포가 전후방 모두 2차 정도 감소되고 수핵이 없는 경우는 최대 신전위가 굴곡위보다 응력이 전후방 0.5차 정도 감소되었다. To observe the change in the status of stresses according to three different postural angulation of an intervertebral disc with or without nucleus pulposus, 6 specimens of a 3-dimensional photoelastic model of the spine were made of epoxy. The nucleus pulposus portion was replaced with silicon in three models, and the three were made without silicon. Through axial application of a vertical compressive load of 8㎏, the peculiar patterns of the isochromatic fringes were observed, Stresses on the intervertebral disc were analyzed according to three different postural angulations of the intervertebral disc with the nucleus pulposus and without the nucleus pulposus. The results of these study are as follow : 1. In an erect neutral posture with the nucleus pulposus, the stress concentration was much increased at the posterior portion rather than at the anterior portion. Also, the high stress was concentrated at the medial and central portion. In an erect neutral posture without the nucleus pulposus, the stress concentration was much increased at the anterior portion rather than at the posterior portion and the stress distribution seemed to be locally concentrated. 2. In a maximal flexed posture, the stress concentration was much increased at the posterior portion rather than at the anterior portion. Comparing the presence of the nucleus pulposus with the absence of the nucleus pulposus, the stress concentration was lower at the anterior portion in the presence of the nucleus pulposus than in the absence of the nucleus pulposus. However, the stress distribution at the posterior portion was nearly same in the two groups. According to the analysis of the stress distribution diagram, as a whole, the stress pattern around the disc was evenly distributed. 3. In a maximal extended posture, the higher concentration of the stress distribution at the anterior and medial portion rather than in the posterior and lateral portion was observed. The stress concentration was higher in the presence of the nucleus pulposus than in the absence of the nucleus pulposus. 4. Comparing the maximal flexed posture with the erect neutral posture, the stress concentration in the flexed posture was much decreased in the posterior portion rather than in the erect neutral posture, and an even distribution of the stress pattern in the flexed posture was observed. 5. In the absence of the nucleus pulposus, at the anterior and posterior portion, the stress concentration in the extended posture was much decreased compared with the flexed posture. In the absence of the nucleus pulposus, at the anterior and posterior portion, the stress concentration in the extended posture was much decreased compared with the flexed posture.

한국성인 남성의 골밀도에 관한 연구

朴泰永,柳錫柱,李聖喆,金明昊 단국대학교 1995 論文集 Vol.29 No.-

Authors has analysed bone mineral density(BMD) of spine and proximal femur of 55 normal male patients who visited Dankook University hospital, college of medicine from may 1994 to February 1995. The aims of the study is the investigation of correlation between BMD and age distribution and the change of the BMD. 1. The ages of maximal BMD from the 2nd lumbar spine to the 4th lumbar spine exist between 26 years old and 30 years old. The average decrease rate of BMD is 5% per 10 years from the age the maximal BMD. 2. Te BMD of the 12th thoracic spine and 1st lumbar spine is lower than that of the average BMD from the 2nd. to 4th lumbar spine. 3. The correlation cofficient of the lateral projection with anteroposterior projection is 0.632 at the 2nd lumbar spine and 0.500 at the 3rd lumbar spine. 4. The ages of maximal BMD of proximal femur exist between 21 years old and 25 years old. The average decrease rate of BMD is 7% per 10 years from the age of maximal BMD.

Efficiency of Hydroxyl Radical Production of Gamma irradiated TiO₂

Myun Joo Lee,Jin Ho Jung 대한환경공학회 2001 대한환경공학회 학술발표논문집 Vol.2001 No.12

MRP1 Polymorphisms Associated With Citalopram Response in Patients With Major Depression

Lee, Sung Hee,Lee, Min-Soo,Lee, Ji Hyun,Kim, So Won,Kang, Rhee-Hun,Choi, Myoung-Jin,Park, Sang Jin,Kim, Se Joo,Lee, Jae Myun,Cole, Susan P.C.,Lee, Min Goo Lippincott Williams Wilkins, Inc. 2010 JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY Vol.30 No.2

Multidrug resistance protein 1 (MRP1, ABCC1) transports antidepressive agents in the endothelial cells of the blood-brain barrier. Therefore, polymorphisms in the MRP1 gene may affect the treatment response of antidepressants. This study was aimed to identify the association between genetic variations in MRP1/ABCC1 and the therapeutic response to the antidepressant citalopram. One hundred and twenty-three patients who had been treated with citalopram monotherapy to control their major depressive disorder were recruited, and genotype data from 64 patients who had completed their 8-week follow-up were evaluated together with those from 100 controls. Nine MRP1 single nucleotide polymorphisms (SNPs) showing more than 5% allele frequency in the Korean population were analyzed. The c.4002G>A, a synonymous SNP in exon 28, showed a strong association with the remission state at 8 weeks (P = 0.005, odds ratio [OR], 4.7, 95% confidence interval [CI], 1.5∼14.7). The c.4002G>A forms a linkage disequilibrium block with 3 other SNPs including c.5462T>A in the 3' untranslated region. Accordingly, the haplotype showed a significant association with the remission state (P = 0.014). Subsequent molecular studies also supported the association between these MRP1 polymorphisms and the citalopram response. Thus, kinetic studies using MRP1-enriched membrane vesicles revealed that citalopram is a substrate of MRP1 (Km = 1.99 μM, Vmax = 137 pmol/min per milligram protein). In addition, individuals with c.4002G>A or c.5462T>A polymorphisms showed higher MRP1 mRNA levels in peripheral blood cells. These results suggest that MRP1 polymorphisms may be a predictive marker of citalopram treatment in major depression.

오존을 이용한 tert - 부틸알코올의 분해에 있어서 감마선 조사영향

이면주(Myun Joo Lee),진준하(Joon Ha Jin) 大韓環境工學會 1994 대한환경공학회지 Vol.16 No.7

감마선 조사에 의한 TNT 분해에 용존산소가 미치는 영향에 관한 연구

이병진 ( Byung Jin Lee ),유대현 ( Dae Hyun Lee ),이재광 ( Jae Kwang Lee ),이면주 ( Myun Joo Lee ),김유리 ( Yu Ri Kim ),한범수 ( Bum Soo Han ) 한국물환경학회 2004 한국물환경학회·대한상하수도학회 공동 춘계학술발표회 Vol.2004 No.-

Mitochondrial oxidative phosphorylation system is recruited to detergent-resistant lipid rafts during myogenesis

Kim, Bong-Woo,Lee, Joong-Won,Choo, Hyo-Jung,Lee, Chang Seok,Jung, Soon-Young,Yi, Jae-Sung,Ham, Young-Mi,Lee, Joo-Hyung,Hong, Jin,Kang, Min-Ju,Chi, Sung-Gil,Hyung, Seok-Won,Lee, Sang-Won,Kim, Hwan Myun WILEY-VCH Verlag 2010 Proteomics Vol.10 No.13

<P>Since detergent-resistant lipid rafts play important roles in the signal transduction for myogenesis, their comprehensive proteomic analysis could provide new insights to understand their function in myotubes. Here, the detergent-resistant lipid rafts were isolated from C2C12 myotubes and analyzed by capillary RPLC/MS/MS. Among the 327 proteins (or protein groups) identified, 28% were categorized to the plasma membrane or raft proteins, 29% to mitochondria, 20% to microsomal proteins, 10% to other proteins, and 13% to unknown proteins. The localization of oxidative phosphorylation (OXPHOS) complexes in the sarcolemma lipid rafts was further confirmed from C2C12 myotubes by cellular fractionation, surface-biotin labeling, immunofluorescence, and lipid raft fractionation. After adding exogenous cytochrome c, the sarcolemma isolated from myotubes had an ability to consume oxygen in the presence of NADH or succinate. The generation of NADH-dependent extracellular superoxide was increased by inhibiting or downregulating OXPHOS I, III, and IV in myotubes, indicating that OXPHOS proteins are major sources for extracellular ROS in skeletal muscle. With all these data, we can conclude that OXPHOS proteins are associated with the sarcolemma lipid rafts during C2C12 myogenesis to generate extracellular ROS.</P>

포스터발표 : 하폐수처리 ; 감마선 조사에 의한 TNT 분해에 용존산소가 미치는 영향에 관한 연구

이병진 ( Byung Jin Lee ),유대현 ( Dae Hyun Lee ),이재광 ( Jae Kwang Lee ),이면주 ( Myun Joo Lee ),김유리 ( Yu Ri Kim ),한범수 ( Bum Soo Han ) 대한상하수도학회 2004 공동춘계 학술발표회 논문집 Vol.2004 No.-